The nature of the differential inhibition of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes by the Phytolacca americana protein.

abstract：:Toll-like receptors (TLRs) constitute a multi-gene family, which plays a pivotal role in sensing invading pathogens by virtue of conserved microbial patterns. TLR repertoire of chicken and zebra finch has been well studied. However TLR family of other avian species is yet to be characterized. In the present study, we ...

journal_title：Molecular biology reports

authors： Ramasamy KT,Reddy MR,Verma PC,Murugesan S

更新日期：2012-08-01 00:00:00

abstract：:Yellow lupin seeds (Lupinus luteus) cytoplasmic tRNAGlu was isolated and the primary structure was determined to be: (sequence in text) AGU CCCGGCGACGGAACCAOH. It is 76 nucleotides long and contains 8 modified nucleosides: 2 residues of pseudouridine, ribothymidine, 3 dihydrouridines, 5-methylcytosine and 1-methyladen...

journal_title：Molecular biology reports

authors： Barciszewska M,Barciszewski J

更新日期：1988-01-01 00:00:00

abstract：:The programmed cell death (PCD) is important in maintaining the cell number homoeostasis of tissues and organs in metazoan. This process is regulated by the inhibitors of apoptosis proteins (IAPs). The function and mechanism of IAPs have been well studied in animal embryonic development and human cancers. However, the...

journal_title：Molecular biology reports

authors： He HJ,Hou L,Wang JX,Zhao XF

更新日期：2012-02-01 00:00:00

abstract：:Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium lat...

journal_title：Molecular biology reports

authors： Sinha VB,Grover A,Singh S,Pande V,Ahmed Z

更新日期：2014-09-01 00:00:00

abstract：:LNX (Ligand of Numb-protein X) was originally isolated as a binding partner to the cell-fate Determinant Numb during development, and then identified to act as a RING finger-type E3 ubiquitin ligase for the ubiquitylation and degradation of Numb. LNX contains 4 PDZ domains which are proved to play a central role in or...

journal_title：Molecular biology reports

authors： Zheng D,Sun Y,Gu S,Ji C,Zhao W,Xie Y,Mao Y

更新日期：2010-06-01 00:00:00

abstract：:The degeneration of retinal pigment epithelium (RPE) cells in the sub retinal pigment epithelial space and choroid is an initial pathological characteristic for the age-related macular degeneration which is the leading cause of severe vision loss in old people. Moreover, oxidative stress is implicated as a major induc...

journal_title：Molecular biology reports

authors： Li DD,Zhong BW,Zhang HX,Zhou HY,Luo J,Liu Y,Xu GC,Luan CS,Fang J

更新日期：2016-10-01 00:00:00

abstract：:Recent Genome-Wide Association Studies have identified several single nucleotide polymorphisms (SNPs) associated with breast cancer (BC) among women of Asian, European, and African-American ancestry. Nevertheless, the contribution of these variants in the South American population is unknown. Furthermore, there is lit...

journal_title：Molecular biology reports

authors： Elematore I,Gonzalez-Hormazabal P,Reyes JM,Blanco R,Bravo T,Peralta O,Gomez F,Waugh E,Margarit S,Ibañez G,Romero C,Pakomio J,Roizen G,Di Capua GA,Jara L

更新日期：2014-06-01 00:00:00

abstract：:Because of the importance of androgens to prostate cancer (PCa) development, several candidate genes along androgen pathway have been under intensive study. Given the role of the molecular chaperone HSP70 in the regulation of the androgen receptor (AR) transactivation function, we first chose to explore the associatio...

journal_title：Molecular biology reports

authors： Sfar S,Saad H,Mosbah F,Chouchane L

更新日期：2008-09-01 00:00:00

abstract：:Membrane-bound Δ9 desaturase perform oxygenated desaturation reactions to insert the first double bonds within fatty acyl chains between C9 and C10 positions of most saturated substrates. Arthrospira platensis, a blue green microalga, is an important source of polyunsaturated fatty acids (PUFA) such as oleic, linoleic...

journal_title：Molecular biology reports

authors： Ben Amor F,Ben Hlima H,Abdelkafi S,Fendri I

更新日期：2018-12-01 00:00:00

abstract：:Heterogeneous nuclear ribonucleoprotein particles (HnRNP) were separated in metrizamide density gradients, into two fractions migrating to 1.31 g ml-1 and 1.18 g ml-1, respectively. Proteins associated with each of these fractions were analysed by SDS-acrylamide gel electrophoresis. It is shown that the whole proteins...

journal_title：Molecular biology reports

authors： Houssais JF

更新日期：1977-03-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:Free cytoplasmic mRNPs were isolated from human placenta. An activity of RNase was associated with these particles but was mostly inhibited by a labile protein inhibitor. Both RNase and RNase inhibitor were extractable from mRNPs by 0.5 M KCl. The nature of the association of the RNase-RNase inhibitor complex with mRN...

journal_title：Molecular biology reports

authors： Gileadi O,Lorberboum H,de Groot N,Hochberg AA

更新日期：1984-01-01 00:00:00

abstract：:Nuclear magnetic resonance (NMR) spectroscopy is a useful biophysical technique to study the ligand-protein interaction. In this report, we have used bacterially produced ERβ and its domains for studying the functional analysis of ligand-protein interaction. Briefly, ERβ and its transactivation domain (TAD) and ligand...

journal_title：Molecular biology reports

authors： Paramanik V,Thakur MK

更新日期：2011-10-01 00:00:00

abstract：:The protease activity of gp63 from L. major was studied in relation to tunicamycin induced N-deglycosylation. It was found that after tunicamycin treatment, a N-deglycosylated product of gp63 with protease activity is present at the cell surface of Leishmania promastigote. ...

journal_title：Molecular biology reports

authors： Hernandez C,Manenti S,Hernandez AG

更新日期：1992-05-01 00:00:00

abstract：:The lily-of-the-valley Convallaria (Asparagaceae) consists of three herbaceous perennial species. The plants are commonly found in northern hemisphere, and are best-known for their ornamental and pharmaceutical value. In order to assess the genetic structure, diversity and demographic history of Convallaria species, 1...

journal_title：Molecular biology reports

authors： Lu QX,Gao J,Wu JJ,Zhou X,Wu X,Li MD,Wei YK,Wang RH,Qi ZC,Li P

更新日期：2020-04-01 00:00:00

abstract：:Histone H1 is know to play a role in the formation and maintenance of higher-order chromatin structure. It has been recently suggested that the linker histone might be also involved in the regulation of the activity of individual genes. If H1 is a regulatory factor in eukaryotic gene transcription, it should possess s...

journal_title：Molecular biology reports

authors： Zlatanova J,Yaneva J

更新日期：1991-02-01 00:00:00

abstract：:ERBB2/HER2/NEU, a member of the epidermal growth factor receptor family, is overexpressed in more than 25 % of non-small cell lung cancer and is considered to be a significant and independent prognostic factor in lung cancer. Here we generated a lung specific HER2 overexpressing transgenic mouse model. In this model, ...

journal_title：Molecular biology reports

authors： Zeng S,Yang Y,Tan Y,Lu C,Pan Y,Chen L,Lu G

更新日期：2012-08-01 00:00:00

abstract：:An extensive study on spontaneous and 5-Fluorodeoxyuridine induced fragile sites identified Xq31 in cattle (Bos taurus) and (Xq24, Xq26) in sheep (Ovis aries) in addition to several autosomal fragile sites (under publication). A ZOO-FISH study using three cloned human fragile-X probes with CCG/CGG(n) trinucleotide rep...

journal_title：Molecular biology reports

authors： Ali A,Thomsen PD,Babar ME

更新日期：2009-03-01 00:00:00

abstract：:70S RNA has been prepared from mouse mammary tumor virus (MMTV) produced by the GR tumor cell line. After denaturation for 3 min at 60 degrees C the RNA was applied to a sucrose gradient and molecules sedimenting between 10-16S were selected and passed over an oligo-dT cellulose column. The poly A containing RNA fract...

journal_title：Molecular biology reports

authors： Klemenz R,Reinhardt M,Diggelmann H

更新日期：1981-05-22 00:00:00

abstract：:Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. Direct exposure of human hepatoma cell line SMMC-7221 to hydrogen peroxide (H2O2) can induce apoptosis characterized by morphological evidence and fragmentation of DNA assayed by terminal deoxynucleotidyl transferase ...

journal_title：Molecular biology reports

authors： Huang C,Li J,Zheng R,Cui K

更新日期：2000-03-01 00:00:00

abstract：:Hepatitis B virus (HBV) as the main prevalent infectious agent, play important roles in inducing severe liver diseases. Previous studies demonstrated that during prolonged forms of hepatitis B infection including chronic, asymptomatic and occult forms, patients are unable to eradicate HBV from hepatocytes completely. ...

journal_title：Molecular biology reports

authors： Karimi-Googheri M,Arababadi MK

更新日期：2014-05-01 00:00:00

abstract：:p53 helps in maintaining genomic stability by undergoing cellular arrest, DNA repair or cellular apoptosis during DNA damage. So, as to find the association of p53Arg 72 Pro towards lung carcinogenesis and overall survival of North Indian lung cancer patients, single nucleotide polymorphic variant (rs1042522) was anal...

journal_title：Molecular biology reports

authors： Kumari A,Bahl C,Singh N,Behera D,Sharma S

更新日期：2016-12-01 00:00:00

abstract：:Macroautophagy is a regulated bulk degradation process of cellular components, mainly long-lived proteins or cytoplasmic organelles. Nutrient depletion is a classic inducer of macroautophagy. In this report, we have induced heat-mediated macroautophagy in several cell lines in the absence of nutrient depletion. Heat t...

journal_title：Molecular biology reports

authors： Zhao Y,Gong S,Shunmei E,Zou J

更新日期：2009-11-01 00:00:00

abstract：:The oriental melon (Cucumis melo var. makuwa), called 'chamoe' in Korean, is a popular fruit crop cultivated mainly in Asia and a high-market value crop in Korea. To provide molecular breeding resources for chamoe, we developed and characterized genomic SSR markers from the preliminary Illumina read assemblies of Gotg...

journal_title：Molecular biology reports

authors： Park I,Kim J,Lee J,Kim S,Cho O,Yang K,Ahn J,Nahm S,Kim H

更新日期：2013-12-01 00:00:00

abstract：:Variants of the transcription factor 7-like 2 gene (TCF7L2) have been associated with type 2 diabetes and cardiovascular disease in different populations. Here we investigated the potential association of the rs7903146 polymorphism in the TCF7L2 gene with clinical profile of end-stage renal disease (ESRD) patients. We...

journal_title：Molecular biology reports

authors： Buraczynska M,Zukowski P,Ksiazek P,Kuczmaszewska A,Janicka J,Zaluska W

更新日期：2014-06-01 00:00:00

abstract：:Acute and chronic viral hepatitis infections are corresponding to increase the risk of different types of hematological malignancies especially with leukemia. In this study the serological and molecular markers of hepatitis viruses were evaluated in patients with different types of leukemia in comparing with control g...

journal_title：Molecular biology reports

authors： Mirzaee M,Yaghobi R,Ramzi M,Roshan Nia M

更新日期：2012-02-01 00:00:00

abstract：:This study was designed to identify the differential expression of the canonical transient receptor potential (TRPC) channels in the left ventricle of spontaneously hypertensive rats (SHR). Echocardiography studies were performed to compare the left ventricular function in SHR vs. Wistar-Kyoto rats (WKY), and the mRNA...

journal_title：Molecular biology reports

authors： Liu FF,Ma ZY,Li DL,Feng JB,Zhang K,Wang R,Zhang W,Li L,Zhang Y

更新日期：2010-07-01 00:00:00

abstract：:Substantial evidence has demonstrated that platelet-derived growth factor-D (PDGF-D) is tightly associated with the development and progression of tumors. However, its biological functions in esophageal squamous cell carcinoma (ESCC) remain to be delineated. In this study, we found that expressions of PDGF-D mRNA and ...

journal_title：Molecular biology reports

authors： Han Y,Guo XH,Zheng QF,Zhu YL,Fan YY,Zhang XY

更新日期：2013-03-01 00:00:00

abstract：:Recently, differentiated somatic cells had been reprogrammed to pluripotential state in vitro, and various tissue cells had been elicited from those cells. Epigenetic modifications allow differentiated cells to perpetuate the molecular memory needed for the cells to retain their identity. DNA methylation and histone d...

journal_title：Molecular biology reports

authors： Zhang XM,Li QM,Su DJ,Wang N,Shan ZY,Jin LH,Lei L

更新日期：2010-03-01 00:00:00

abstract：:The aim of this study was to explore whether the cytotoxic T lymphocyte antigen-4 (CTLA-4) +49 A/G polymorphism confers susceptibility to rheumatoid arthritis (RA). A meta-analysis was conducted on the associations between CTLA-4 +49 A/G polymorphism and RA using; 1) allele contrast, 2) the recessive model, 3) the dom...

journal_title：Molecular biology reports

authors： Lee YH,Bae SC,Choi SJ,Ji JD,Song GG

更新日期：2012-05-01 00:00:00