Induction of macroautophagy by heat.

abstract：:Rice production in recent years is highly affected by rapidly increasing temperatures in the tropical and sub-tropical countries, which threatens the sustainable production in near future. Hence, understanding the heat tolerance mechanism and evolving tolerant varieties is an immense need in the staple crop rice. An e...

journal_title：Molecular biology reports

authors： Wahab MMS,Akkareddy S,Shanthi P,Latha P

更新日期：2020-03-01 00:00:00

abstract：:Recombinant plasmids carrying a highly curved DNA structure are sometimes unstable in Escherichia coli. In order to know the underlying mechanism, several plasmids carrying one or two highly bent DNA segment(s) from the human adenovirus type 2 (Ad2) enhancer and/or origin region of phage lambda replication were system...

journal_title：Molecular biology reports

authors： Ohyama T,Miyano M,Sakuma S

更新日期：1999-12-01 00:00:00

abstract：:Myocilin (MYOC) gene is expressed in many ocular tissues, including the trabecular meshwork, a specialized eye tissue essential in regulating intraocular pressure. Many mutations in MYOC have been detected in primary open-angle glaucoma (POAG). We investigated whether MYOC mutations contributed to the susceptibility t...

journal_title：Molecular biology reports

authors： Qu X,Zhou X,Zhou K,Xie X,Tian Y

更新日期：2010-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs that function in transcriptional and post-transcriptional regulation of gene expression. Several miRNAs have been implicated in regulating prostate cancer (PCa) progression. Deregulations of miRNA regulatory networks have been reported in ERG positive PCa, which accounts fo...

journal_title：Molecular biology reports

authors： Bakkar A,Alshalalfa M,Petersen LF,Abou-Ouf H,Al-Mami A,Hegazy SA,Feng F,Alhajj R,Bijian K,Alaoui-Jamali MA,Bismar TA

更新日期：2016-04-01 00:00:00

abstract：:Fluorescent proteins related to and derived from green fluorescent protein (GFP) are widely used as tools for investigating a wide range of biological processes. In particular, GFP and its relatives have been used extensively as qualitative reporters of gene expression in many different organisms, but relatively few s...

journal_title：Molecular biology reports

authors： Lissemore JL,Bayes J,Calvey M,Reineke L,Colagiavanni A,Tscheiner M,Mascotti DP

更新日期：2009-05-01 00:00:00

abstract：:The response of glycolysis to exposure of glucose in non-growing S. cerevisiae cells from diauxic shift was monitored. The result was compared to a kinetic model of glycolysis with branches to glycogen, trehalose, glycerol, and succinate. Experimental data at steady-state concentrations of metabolites in the upper par...

journal_title：Molecular biology reports

authors： Albers E,Bakker BM,Gustafsson L

更新日期：2002-01-01 00:00:00

abstract：:The complete mitochondrial genome 15,650 bp in size of the Deracantha onos has been determined. The gene content, base composition and codon usage of D. onos are coincident to typical hexapods mitochondrial genomes. Genes arrangement of D. onos is identical to Gryllotalpa orientalis, Ruspolia dubia and Anabrus simplex...

journal_title：Molecular biology reports

authors： Zhou Z,Huang Y,Shi F,Ye H

更新日期：2009-01-01 00:00:00

abstract：:Helicteres hirsuta Lour. (H. hirsuta) has been considered as a herbal medicine for the treatment of malaria and diabetes but limited studies have been conducted on its anticancer and antibacterial properties. In this study, the in vitro antibacterial and anticancer properties of the leaf and stem extracts and their tw...

journal_title：Molecular biology reports

authors： Pham HNT,Sakoff JA,Bond DR,Vuong QV,Bowyer MC,Scarlett CJ

更新日期：2018-12-01 00:00:00

abstract：:Macrophage activation is modulated by both environmental cues and endogenous programs. In the present study, we investigated the role of a PAQR family protein, monocyte to macrophage differentiation-associated (MMD), in macrophage activation and unveiled its underlying molecular mechanism. Our results showed that whil...

journal_title：Molecular biology reports

authors： Liu Q,Zheng J,Yin DD,Xiang J,He F,Wang YC,Liang L,Qin HY,Liu L,Liang YM,Han H

更新日期：2012-05-01 00:00:00

abstract：:The melanocortin-4 receptor (MC4R) plays an important role in weight and energy homeostasis and it is associated with lower risk to develop obesity and lower body mass index. The contribution of MC4R mutation to obesity in Vojvodina (Northern Province of Serbia), known as a region with the largest number of overweight...

journal_title：Molecular biology reports

authors： Stokić E,Djan M,Vapa Lj,Djan I,Plećas A,Srdić B

更新日期：2010-01-01 00:00:00

abstract：:microRNAs are short, non-coding RNAs, that exert a posttranscriptional control on protein synthesis by mRNA interference. They are involved in normal and pathological embryologic development, as well as in adult life pathology, from myocardial infarction to cancer. There are several brain-specific species of microRNA,...

journal_title：Molecular biology reports

authors： Enciu AM,Popescu BO,Gheorghisan-Galateanu A

更新日期：2012-03-01 00:00:00

abstract：:Through the process of alternative splicing, proteins with distinct biological functions and localisations are generated from a single gene. The mitochondrial folate metabolism enzyme methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) has been receiving attention in recent years as one of the most frequently upregulat...

journal_title：Molecular biology reports

authors： Nicolaidou V,Papaneophytou C,Koufaris C

更新日期：2020-09-01 00:00:00

abstract：:Responses of plants to salinity stress and the development of salt tolerance are extremely complex. Proteomics is a powerful technique to identify proteins associated with a particular environmental or developmental signal. We employed a proteomic approach to further understand the mechanism of plant responses to sali...

journal_title：Molecular biology reports

authors： Fatehi F,Hosseinzadeh A,Alizadeh H,Brimavandi T,Struik PC

更新日期：2012-05-01 00:00:00

abstract：:We investigated phenotypic variations for pod shattering, pod length and number of seeds per pod in large germplasm collections of Brassica juncea (2n = 36; AABB) and its progenitor species, B. rapa (2n = 20; AA) and B. nigra (2n = 16; BB). Pod shatter resistance was measured as energy required for rupturing a mature ...

journal_title：Molecular biology reports

authors： Kaur J,Akhatar J,Goyal A,Kaur N,Kaur S,Mittal M,Kumar N,Sharma H,Banga S,Banga SS

更新日期：2020-04-01 00:00:00

abstract：:The fat mass and obesity associated gene (FTO) has been widely reported to be associated with fat mass or fat deposition in different species. In the present study, we cloned both promoter and coding regions of the gene in pigs with over 5 Kb of sequence for the former region and 1,596 bp for the latter region. Compar...

journal_title：Molecular biology reports

authors： Huang J,Yang Y,Liu G,Zhang J,Dong X,Bai Y,Fang M

更新日期：2011-04-01 00:00:00

abstract：:Severe malaria (SM) caused by Plasmodium falciparum (Pf) infection has been associated with life-threatening anemia, metabolic acidosis, cerebral malaria and multiorgan dysfunction. It may lead to death if not treated promptly. RNASE 3 has been linked to Pf growth inhibition and its polymorphisms found associated with...

journal_title：Molecular biology reports

authors： Mukhi B,Gupta H,Wassmer SC,Anvikar AR,Ghosh SK

更新日期：2020-11-01 00:00:00

abstract：:The response of the respiratory subsystem of oxidative phosphorylation to the environmental pollutant, 2,2',5,5'-tetrachlorobiphenyl (2,2',5,5'-TCB) was investigated by modular kinetic approach. The effects of 20 microM 2,2',5,5'-TCB on the activity of the respiratory chain modules in rat liver mitochondria oxidizing ...

journal_title：Molecular biology reports

authors： Mildaziene V,Nauciene Z,Krab K

更新日期：2002-01-01 00:00:00

abstract：:The Follicle stimulating hormone beta polypeptide (FSHβ) gene has been investigated as a candidate gene for litter size because of its role in maturation of small and medium follicles into ovulating large follicles. Genes coding follicle stimulating hormone have been found to have significant effects on litter size in...

journal_title：Molecular biology reports

authors： Magotra A,Naskar S,Das B,Ahmad T

更新日期：2015-02-01 00:00:00

abstract：:The cell cycle is a complex and strictly controlled process, consisting of different phases. Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the dereg...

journal_title：Molecular biology reports

authors： Caglar HO,Biray Avci C

更新日期：2020-04-01 00:00:00

abstract：:Emergence of MDR 'superbugs' inflamed a severe sense of urgency amongst scientists aiming at the discovery of novel potential drug molecules. Bacteria of the genus Streptomyces are really worth investigating for their immense potential to produce natural compounds of pharmaceutical importance. In the present study, th...

journal_title：Molecular biology reports

authors： Kumar P,Chauhan A,Kumar M,Kuanr BK,Solanki R,Kapur MK

更新日期：2020-09-01 00:00:00

abstract：:The aim of this study was to develop microsatellite markers as a tool to study population structure, genetic diversity and effective population size of Echinopsis chiloensis, an endemic cactus from arid and semiarid regions of Central Chile. We developed 12 polymorphic microsatellite markers for E. chiloensis using ne...

journal_title：Molecular biology reports

authors： Ossa CG,Larridon I,Peralta G,Asselman P,Pérez F

更新日期：2016-12-01 00:00:00

abstract：:This study aims to investigate the apoptotic and anti-angiogenic effect of Zoledronic acid on hormone-refractory prostate cancer cell lines. XTT cell proliferation assay used to assess cytotoxicity. Caspase 3/7 activity and DNA fragmentation were measured to verify apoptosis. Angiogenic cytokine profiles investigated ...

journal_title：Molecular biology reports

authors： Gokalp C

更新日期：2020-10-01 00:00:00

abstract：:Ribosomal protein S3 (RPS3) is a component of the 40S ribosomal subunit. It is known to function in ribosome biogenesis and as an endonuclease. RPS3 has been shown to be over expressed in colon adenocarcinoma but its role in colon cancer is still unknown. In this study, we aim at determining the expression levels of R...

journal_title：Molecular biology reports

authors： Alam E,Maaliki L,Nasr Z

更新日期：2020-08-01 00:00:00

abstract：:Schistosomiasis, a disease caused by helminth parasites of genus Schistosoma. Its treatment intensively depends on single drug, praziquantel which increases the risk of development of drug-resistant parasite. Inhibitors of human HDAC are profoundly reported as novel anti-cancer drugs and used as new anit-parasitic age...

journal_title：Molecular biology reports

authors： Singh R,Pandey PN

更新日期：2015-03-01 00:00:00

abstract：:Quercus acutissima is native to eastern Asia. It has a wide distribution in China and China is an important component in understanding the ecology and genetic structure of this species. Q. acutissima attained high economic value for hardwood product and can be managed as an energy tree species. To investigate the gene...

journal_title：Molecular biology reports

authors： Zhang YY,Fang YM,Yu MK,Li XX,Xia T

更新日期：2013-06-01 00:00:00

abstract：:The Rv3203 (LipV) of Mycobacterium tuberculosis (Mtb) H37Rv, is annotated as a member of Lip family based on the presence of characteristic consensus esterase motif ‘GXSXG’. In vitro culture studies of Mtb H37Ra indicated that expression of Rv3203 gene was up-regulated during acidic stress as compared to normal wherea...

journal_title：Molecular biology reports

authors： Singh G,Arya S,Narang D,Jadeja D,Singh G,Gupta UD,Singh K,Kaur J

更新日期：2014-01-01 00:00:00

abstract：:Adequate metabolic adaptation of key tissues playing an essential role for bioenergetic homeostasis and lactogenesis is critical in cows to adapt to changes in energy requirements and physiological processes during the lactation period. Mitochondria are recognized as central to meet energy needs and maintaining of met...

journal_title：Molecular biology reports

authors： Weikard R,Kuehn C

更新日期：2018-10-01 00:00:00

abstract：:Schizophrenia is one of the neuropathological disorders, which are associated with dopamine and its receptors. In recent years, it has been shown that mRNA of D3, D4 and D5 dopamine receptor (DRD3, DRD4, DRD5) subtypes is expressed in human peripheral blood lymphocytes (PBL). A total 55 schizophrenic patients and 51 h...

journal_title：Molecular biology reports

authors： Urhan-Kucuk M,Erdal ME,Ozen ME,Kul S,Herken H

更新日期：2011-04-01 00:00:00

abstract：:Sheep are valuable resources for the wool industry. Wool growth of Aohan fine wool sheep has cycled during different seasons in 1 year. Therefore, identifying genes that control wool growth cycling might lead to ways for improving the quality and yield of fine wool. In this study, we employed Agilent sheep gene expres...

journal_title：Molecular biology reports

authors： Liu N,Li H,Liu K,Yu J,Cheng M,De W,Liu J,Shi S,He Y,Zhao J

更新日期：2014-08-01 00:00:00

abstract：:Abiotic stresses such as salinity and drought have adverse effects on plants. In the present study, a Na(+)/H(+) antiporter gene homologue (LfNHX1) has been cloned from a local halophyte grass (Leptochloa fusca). The LfNHX1 cDNA contains an open reading frame of 1,623 bp that encodes a polypeptide chain of 540 amino a...

journal_title：Molecular biology reports

authors： Rauf M,Shahzad K,Ali R,Ahmad M,Habib I,Mansoor S,Berkowitz GA,Saeed NA

更新日期：2014-03-01 00:00:00