Ribosomal protein S3 selectively affects colon cancer growth by modulating the levels of p53 and lactate dehydrogenase.

abstract：:Genetic analyses have contributed to improvements of economically important traits derived from adipose tissue such as fatty acid composition in beef. Elongation of very long chain fatty acids (ELOVL) genes encode for the enzymes that play an important role in elongation of long-chain fatty acids. In this study, we ai...

journal_title：Molecular biology reports

authors： Matsumoto H,Shimizu Y,Tanaka A,Nogi T,Tabuchi I,Oyama K,Taniguchi M,Mannen H,Sasazaki S

更新日期：2013-04-01 00:00:00

abstract：:The cytotoxic T lymphocyte-associated antigen 4 gene (CTLA4) has a crucial role in regulation of T cell proliferation and mediates T cell apoptosis by encoding the T cell receptor. Schizophrenia (SCZ) patients often have abnormalities in terms of the function and development of the immune system. The aim of the presen...

journal_title：Molecular biology reports

authors： Kordi-Tamandani DM,Vaziri S,Dahmardeh N,Torkamanzehi A

更新日期：2013-08-01 00:00:00

abstract：:This study investigated the role of the mevalonate pyrophosphate decarboxylase gene in the triterpene biosynthetic pathway of Ganoderma lucidum. The mevalonate pyrophosphate decarboxylase gene (mvd) was isolated using a degenerate primer-PCR technique. An analysis of the Gl-mvd transcription profile revealed a positiv...

journal_title：Molecular biology reports

authors： Shi L,Qin L,Xu Y,Ren A,Fang X,Mu D,Tan Q,Zhao M

更新日期：2012-05-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:This meta-analysis was performed to evaluate the relationships between promoter DNA methylation in tumor suppressor gene p16 and gastric carcinogenesis. The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library and CBM databases were searched for relevant articles published before November 1s...

journal_title：Molecular biology reports

authors： Wang HL,Zhou PY,Liu P,Zhang Y

更新日期：2014-07-01 00:00:00

abstract：:Two calcium carbonate crystal polymorphs, aragonite and calcite, are the main inorganic components of mollusk shells. Some fossil evidences suggest that aragonite shell is more ancient than calcite shell for the Bivalvia. But, the molecular biology evidence for the above deduction is absent. In this study, we searched...

journal_title：Molecular biology reports

authors： Wang X,Li L,Zhu Y,Song X,Fang X,Huang R,Que H,Zhang G

更新日期：2014-11-01 00:00:00

abstract：:Previous data on association between CYP2E1 Rsa I/Pst I polymorphism and oral cancer risk were controversial. To investigate the association between CYP2E1 Rsa I/Pst I polymorphism and oral cancer risk. We performed a meta-analysis to assess the relationship between oral cancer and genotype with English language until...

journal_title：Molecular biology reports

authors： Niu Y,Hu Y,Wu M,Jiang F,Shen M,Tang C,Chen N

更新日期：2012-01-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00

abstract：:Serotonin receptor (5-HT) is a biogenic amine acting as a neurotransmitter and neuromodulator that mediates various aspects of reproduction and gametogenesis. The full-length nucleotide sequence of Haliotis discus hannai encodes a protein of 417 amino acids with a predicted molecular mass of 46.54 kDa and isoelectric ...

journal_title：Molecular biology reports

authors： Sharker MR,Sukhan ZP,Kim SC,Lee WK,Kho KH

更新日期：2020-01-01 00:00:00

abstract：:It has been demonstrated that ACSL3 and ACSL5 play important roles in fat metabolism. To investigate the primary functions of ACSL3 and ACSL5 and to evaluate their expression levels during goose fatty liver development, we cloned the ACSL3 and ACSL5 coding domain sequences (CDSs) of geese using RT-PCR and analyzed the...

journal_title：Molecular biology reports

authors： He H,Liu HH,Wang JW,Lv J,Li L,Pan ZX

更新日期：2014-01-01 00:00:00

abstract：:Hereditary hearing loss is a genetically heterogeneous disorder. Mutations in connexin 26 (CX26), are a major cause in many countries and are largely dependent on ethnic groups. The purpose of our study was to evaluate the prevalence of GJB2 mutations among affected individuals from south of Iran. Fifty patients prese...

journal_title：Molecular biology reports

authors： Hashemi SB,Ashraf MJ,Saboori M,Azarpira N,Darai M

更新日期：2012-12-01 00:00:00

abstract：:The full length cDNA sequence of the Tpt1/TCTP (Tumor protein, Translationally-controlled1) gene was identified from Common Carp (Cyprinus carpio, Cyprinidae), and was designated as CcTpt1 gene. The CDS is 510 bp and encodes a 170-amino acid peptide with a typical Tpt1 signature 2 domain, and is a typical Tpt1 protein...

journal_title：Molecular biology reports

authors： Jiang L,Wang Y,Cheng A,Zhang B,Ma L,Liu Y,Sun X

更新日期：2013-10-13 00:00:00

abstract：:Prostaglandin E1 has been used clinically for improving heart diseases. In this study, we examined the effect of Prostaglandin E1 on blood lipid levels, heart protein and genes expression in coronary heart disease (CHD) rats. Female rats were fed either a control diet or hypercholesterolemic diet for 14 weeks. The fee...

journal_title：Molecular biology reports

authors： Liu HJ,Ma JW,Qiao ZY,Xu B

更新日期：2013-12-01 00:00:00

abstract：:The suppressors of cytokine signaling (SOCS) proteins are originally identified as negative regulators of cytokine-activated Janus kinase/signal transducers and activators of transcription signaling pathway, but increasing evidence reveals that SOCS proteins play an important role in the development of type 2 diabetes...

journal_title：Molecular biology reports

authors： Feng X,Tang H,Leng J,Jiang Q

更新日期：2014-01-01 00:00:00

abstract：:Echinococcus granulosus is a parasitic helminth which affects both man and animals. During infection with larval stage of the organism secretory and membrane-bound (S/M) proteins play a meaningful role for evasion of immune system. Antigen B (AgB) is one of them. Present investigation has defined sequence diversity of...

journal_title：Molecular biology reports

authors： Pan D,Bera AK,Bandyopadhyay S,Das S,Rana T,Das SK,Bandyopadhyay S,Manna B,Bhattacharya D

更新日期：2011-03-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) has been investigated extensively at the molecular level. Nevertheless, genome wide study on the temporal and spatial dynamics of the virus is non-existed. To explore this topic, we determined complete coding genome sequences for four PRRSV isolates and analy...

journal_title：Molecular biology reports

authors： Yoon SH,Kim H,Kim J,Lee HK,Park B,Kim H

更新日期：2013-10-12 00:00:00

abstract：:A full length spermidine synthase (PgSPD) cDNA was isolated and characterized from the root of Panax ginseng C. A. Meyer. The cDNA was 1,188 nucleotides long and had an open reading frame of 1,002 bp with a deduced amino acid sequence of 333 residues. The calculated molecular mass of the matured protein is approximate...

journal_title：Molecular biology reports

authors： Parvin S,Kim YJ,Pulla RK,Sathiyamoorthy S,Miah MG,Kim YJ,Wasnik NG,Yang DC

更新日期：2010-02-01 00:00:00

abstract：:The majority of familial breast and ovarian cancers arise from mutations in the BRCA1 and BRCA2 genes. Amplification at the 11q13.5 locus is commonly observed in breast and ovarian cancers. In 2003, Hughes-Davies et al. identified a novel gene (EMSY) at this locus which binds BRCA2 within a region deleted in some canc...

journal_title：Molecular biology reports

authors： Altinisik J,Karateke A,Coksuer H,Ulutin T,Buyru N

更新日期：2011-01-01 00:00:00

abstract：:De novo assemblies of transcriptome sequence of F(1) interspecies hybrids between Mandarin fish Siniperca chuatsi (Basilewsky) (♀) and Golden mandarin fish Siniperca scherzeri Steindachner (♂) were generated using Illumina sequencing. In the present study, 64 microsatellite primer pairs were designed on basis of the t...

journal_title：Molecular biology reports

authors： Huang W,Liang X,Qu C,Cao J,Zhao C,Cao L

更新日期：2013-02-01 00:00:00

abstract：:The cell divisions cycle 42 (Cdc42) gene has been characterized in the fungi, such as Candida albicans, Penicillium marneffei, and Wangiella (Exophiala) dermatitidis, which plays important roles during growth and development. The partial cDNA sequence of Cdc42 of Fonsecaea monophora (F. monophora), designated FmCdc42,...

journal_title：Molecular biology reports

authors： Xie Z,Feng P,Zhang J,Li X,Sun J,Lu C,Huang H,Xi L

更新日期：2012-02-01 00:00:00

abstract：:The association between vitamin D receptor (VDR) gene polymorphisms and risk of benign prostatic hyperplasia (BPH) has been investigated in numerous publications, but published results remain inconclusive. Hence, we conducted this meta-analysis to derive a more precise conclusion. Four polymorphisms (Taq-I, Bsm-I, Apa...

journal_title：Molecular biology reports

authors： Zeng XT,Yao QS,Weng H,Li S,Huang JY,Wang XH

更新日期：2014-10-01 00:00:00

abstract：:J The [Ca2+] regulation of contractile ATPase flux, Jp, in skeletal muscle was analysed by computation of the Response R(Jp) Ca2+ for a 10 Hz range of electrical stimulation frequencies. Results of our analysis of the kinetic controls in ATP free energy metabolism in a network model of contracting muscle (J.A.L. Jenes...

journal_title：Molecular biology reports

authors： Jeneson JA

更新日期：2002-01-01 00:00:00

abstract：:A full-length cDNA encoding common bean (Phaseolus vulgaris L.) sucrose synthase (designated as Pv_BAT93 Sus), which catalyses the synthesis and cleavage of sucrose, was isolated from seeds at 15 days after pollination (DAP) by rapid amplification of cDNA ends (RACE). The full-length cDNA of Pv_BAT93 Sus had a 2,418 b...

journal_title：Molecular biology reports

authors： Abid G,Muhovski Y,Jacquemin JM,Mingeot D,Sassi K,Toussaint A,Baudoin JP

更新日期：2012-02-01 00:00:00

abstract：:The stem cells in freshwater flatworms (planarian) are called neoblasts. Neoblasts are capable of proliferation and differentiation into every cell type, including the gametes. For the investigation of the mechanisms of stem cells proliferation and differentiation the proper evaluation of changes in the cell cycle of ...

journal_title：Molecular biology reports

authors： Ermakov AM,Ermakova ON,Kudravtsev AA,Kreshchenko ND

更新日期：2012-03-01 00:00:00

abstract：:Current study was conducted to investigation of effect of magnetic field on cell dedifferentiation and follow it callus induction derived from mature embryo culture in bread wheat genotypes. For this purpose, a factorial experiment based on completely randomized design was carried out with two wheat genotypes and thre...

journal_title：Molecular biology reports

authors： Kahrizi D,Cheghamirza K,Akbari L,Rostami-Ahmadvandi H

更新日期：2013-02-01 00:00:00

abstract：:Beta(2)-microglobulin (beta(2)m), a protein necessary for proper folding, peptide binding, and surface display of class I antigens plays an important role in immune response. The full-length cDNA containing beta(2)m was cloned from the spleen cDNA library of large yellow croaker Pseudosciaena crocea (Pscr-beta ( 2 ) m...

journal_title：Molecular biology reports

authors： Yu S,Chen X,Ao J

更新日期：2009-09-01 00:00:00

abstract：:Myopalladin (MYPN) and titin (TTN) play key roles in skeletal muscle structural organisation and for this reason they may be functional candidates for meat production traits in pigs. We analysed by PCR-RFLP two polymorphisms previously identified and described in the 3'UTR of MYPN and TTN genes in a group of Italian L...

journal_title：Molecular biology reports

authors： Braglia S,Davoli R,Zappavigna A,Zambonelli P,Buttazzoni L,Gallo M,Russo V

更新日期：2013-12-01 00:00:00

abstract：:Porcine MYOD1 gene has been mapped to swine chromosome (SSC) 2p14-p17, which is involved in the regulation of the proliferation and differentiation of skeletal muscle cells. The LDHA (lactate dehydrogenase A) and COPB1 (coatomer protein complex, subunit beta 1) genes, which map close to MYOD1, are involved in energy m...

journal_title：Molecular biology reports

authors： Qiu H,Xu X,Fan B,Rothschild MF,Martin Y,Liu B

更新日期：2010-01-01 00:00:00

abstract：:The lysyl oxidase-like 2 (LOXL2) protein is a human paralogue of lysyl oxidase (LOX) that functions as an amine oxidase for formation of lysine-derived cross-links found in collagen and elastin. In addition to the C-terminal domains characteristic to the LOX family members, LOXL2 contains four scavenger receptor cyste...

journal_title：Molecular biology reports

authors： Kim YM,Kim EC,Kim Y

更新日期：2011-01-01 00:00:00