Abstract：
:The complete mitochondrial genome 15,650 bp in size of the Deracantha onos has been determined. The gene content, base composition and codon usage of D. onos are coincident to typical hexapods mitochondrial genomes. Genes arrangement of D. onos is identical to Gryllotalpa orientalis, Ruspolia dubia and Anabrus simplex, in that the relative locations of tRNA(Lys) and tRNA(Asp) was different to that of Locusta migratoria. All tRNAs could be folded into the typical cloverleaf secondary structure, excluding tRNA(Ser(AGN)) which forms another structure according to the Steinberg-Cedergren tertiary structure. Sequence analysis of the A + T-rich region with Dot-plot did not find any conspicuous repeat clusters. Two poly-thymine (poly-T) nucleotide stretches of 20 bp and 11 bp in size, which may involved in the recognition of replication origin, were found on the H-strand and L-strand in the A + T-rich region of the D. onos mitogenome, respectively. One open reading frame (ORF) 87 amino acids in size was found on the H-strand, but Protein Blast searches analysis indicated that it was a nonfunctional ORF.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Zhou Z,Huang Y,Shi F,Ye Hdoi
10.1007/s11033-007-9145-8subject
Has Abstractpub_date
2009-01-01 00:00:00pages
7-12issue
1eissn
0301-4851issn
1573-4978journal_volume
36pub_type
杂志文章abstract：:'Molecular sandwiches' composed of two aromatic amino acids separated by a hydrophilic one were found on eleven subspecies of human interferon alpha, on murine interferon alpha 2, and human interferon beta 1. In addition, another type of the sandwiches was found on several species of interferon. This confirms and exte...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/BF00417593
更新日期：1986-01-01 00:00:00
abstract：:Several studies have examined the effects of the tumor necrosis factor-α (TNF-α) -308 A/G and lymphotoxin-α (LT-α) +252 A/G polymorphisms on susceptibility to sarcoidosis, showing mixed results. The purpose of this study was to examine whether the TNF-α -308 A/G and LT-α +252 A/G polymorphisms confer susceptibility to...
journal_title：Molecular biology reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11033-013-2859-x
更新日期：2014-01-01 00:00:00
abstract：:Human Papillomavirus infection is considered as the main etiological factor of cervical cancer (ICC), although, the role of host genetic factors in ICC susceptibility has been increasing. Immunological response is crucial for the prevention of viral associated diseases. Interleukin 1 receptor antagonist (IL-1RN) is co...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-1979-z
更新日期：2012-12-01 00:00:00
abstract：:Common bacterial blight (CBB), incited by Xanthomonas axonopodis pv. phaseoli (Xap), is a serious seed-borne disease of common bean (Phaseolus vulgaris L.) in both temperate and tropical production zones. The line HR45 is highly resistant to Xap infection on leaves and pods in both field and greenhouse. To understand ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-010-0079-1
更新日期：2011-01-01 00:00:00
abstract：:Nerve growth factor (NGF) is required for the differentiation and maintenance of sympathetic and sensory neurons. In the present study, the recombinant expression of human nerve growth factor beta (hNGF-β) gene in rabbit bone marrow mesenchymal stem cells (rMSCs) was undertaken. Recombinant vector containing hNGF-β wa...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-010-0068-4
更新日期：2010-12-01 00:00:00
abstract：:Spermiogenesis is a developmental process undergoing continuous differentiation to drive a diploid spermatogonium towards a haploid sperm cell. This striking transformation from spermatogonium to spermatozoa is made possible by the stage-specific adaption of cytoskeleton and associated molecular motor proteins. KIFC1 ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-1593-0
更新日期：2012-07-01 00:00:00
abstract：:To investigate mechanisms of rat glutathione S-transferase P1 gene (rGSTP1) expression regulation during chemical carcinogenesis. we studied enhancer elements located in the region between -2.5 kb to -2.2 kb. The region was upstream from the start site of transcription and was divided into two major fragments, GPEI an...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1023/a:1011993604051
更新日期：2001-03-01 00:00:00
abstract：:Chrysanthemum indicum L. is a traditional oriental medicinal herb prepared as a tea from flowers that have been used in China and South Korea since ancient times. It has a long history in the treatment of hypertension, inflammation, and respiratory diseases. Among Chrysanthemum species, C. indicum has more active chem...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-020-05844-2
更新日期：2020-10-01 00:00:00
abstract：:Evidence indicates that both S-adenosylmethionine (SAMe) metabolism and intramuscular fat are associated with insulin resistance and type II diabetes. However, it is still unknown whether SAMe have effects on intramuscular adipogenesis. The present study investigated the roles of SAMe in the adipogenic differentiation...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-009-9893-8
更新日期：2010-10-01 00:00:00
abstract：:The aim of this work was to study β-defensin 1 (SBD1) and β-defensin 2 (SBD2) genes in Valle del Belice dairy sheep in order to identify polymorphisms that can be utilized as markers of the analyzed genes, and search for the functional effects and roles of the identified polymorphisms (variation of the amino acid sequ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-011-0694-5
更新日期：2011-11-01 00:00:00
abstract：:Anti-EGFR monoclonal antibodies (anti-EGFR MoAbs) in metastatic colorectal cancer (mCRC) treatment are still not effective in all patients. This study aimed to evaluate the relationship between BRAF V600E mutation and the tumor response of anti-EGFR MoAbs for first-line treatment in mCRC patients. We searched the MEDL...
journal_title：Molecular biology reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11033-013-2974-8
更新日期：2014-03-01 00:00:00
abstract：:Despite the progress on development of new culture media, in vitro-produced embryos still display lower quality when compared to the in vivo-produced counterparts. Coculture has been reconsidered as an alternative to improve embryo quality. Mesenchymal stem cells (MSC) and murine embryonic fibroblasts (MEF) have been ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-018-4329-y
更新日期：2018-12-01 00:00:00
abstract：:Insect molting is an important developmental process of metamorphosis, which is initiated by molting hormone. The molting process includes the activation of dermal cells, epidermal cells separation, molting fluid secretion, the formation of new epidermis and old epidermis excoriation etc. Polyphenol oxidases (PPOs), d...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-2428-8
更新日期：2013-05-01 00:00:00
abstract：:DNA repair capacity (DRC) can be altered based on sequence variations in DNA repair genes, which may result in cancer susceptibility. The current study was to evaluate the association between genetic polymorphisms, including associated haplotypes of xeroderma pigmentosum complementary group D (XPD), and individual sus...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-010-0258-0
更新日期：2011-03-01 00:00:00
abstract：:PaeI, a new restriction endonuclease from Pseudomonas aeruginosa clinical strain was isolated and characterized. It recognizes and cleaves the sequence 5'-GCATG reduced C-3' generating DNA fragments with 3'-tetranucleotide sticky ends. DNAs of pBR322, SV40 and bacteriophage lambda have one, two and six PaeI recognitio...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/BF00778522
更新日期：1985-04-01 00:00:00
abstract：:The tertiary structure of nucleic acids results from an equilibrium between electrostatic interactions of phosphates, stacking interactions of bases, hydrogen bonds between polar atoms and water molecules. Water interactions with ribonucleic acid play a key role in its structure formation, stabilization and dynamics. ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-1452-z
更新日期：2012-05-01 00:00:00
abstract：:Curcumin is a polyphenolic bioactive compound found in the spice turmeric endowed with diverse pharmacological and biological activities. In this study, fluorescence spectroscopy in combination with UV-Vis absorbance spectroscopy was employed to investigate the high affinity binding of curcumin to herring sperm DNA (h...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-013-2530-6
更新日期：2013-07-01 00:00:00
abstract：:Selenium compounds have been widely investigated as novel anticancer agents due to high efficacy and selectivity against cancer cells in recent years. This study aimed to research the potential inhibitory effects of seleno-β-lactoglobulin (Se-β-Lg) on HepG2 cells in vitro. MTT results demonstrated that the synthetized...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-019-04953-x
更新日期：2019-10-01 00:00:00
abstract：:The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-1915-2
更新日期：2012-12-01 00:00:00
abstract：:Mouse U26 has been defined as a 2-aminoadipic 6-semialdehyde dehydrogenase. It was speculated to be a PQQ-dependent AAS dehydrogenase due to the research of demonstrating PQQ as a new B vitamin. We isolated a novel human cDNA from the human fetal brain cDNA library we constructed. Its deduced protein was most related ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-003-2716-4
更新日期：2005-03-01 00:00:00
abstract：:Heavy metals pollution affects the nutritive value of fish. This study examined if the inclusion of dietary hempseed (HS) and hempseed oil (HO) in the diet of the fish could revert the copper-induced toxic effects on muscle fatty acid profile of rohu (Labeo rohita) and mrigal (Cirrhinus mrigala). Fingerlings of both s...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-018-4483-2
更新日期：2019-02-01 00:00:00
abstract：:Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that plays an important role in breast cancer pathophysiology and risk definition, since it regulates the bioavailable fraction of circulating estradiol. Epidemiological studies have evaluated the association between SHBG Asp327Asn polymorphism and breast ca...
journal_title：Molecular biology reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11033-012-1680-2
更新日期：2012-08-01 00:00:00
abstract：:Hepatitis B virus (HBV) as the main prevalent infectious agent, play important roles in inducing severe liver diseases. Previous studies demonstrated that during prolonged forms of hepatitis B infection including chronic, asymptomatic and occult forms, patients are unable to eradicate HBV from hepatocytes completely. ...
journal_title：Molecular biology reports
pub_type： 杂志文章,评审
doi：10.1007/s11033-014-3190-x
更新日期：2014-05-01 00:00:00
abstract：:Toll-like receptors (TLRs) constitute a multi-gene family, which plays a pivotal role in sensing invading pathogens by virtue of conserved microbial patterns. TLR repertoire of chicken and zebra finch has been well studied. However TLR family of other avian species is yet to be characterized. In the present study, we ...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-012-1709-6
更新日期：2012-08-01 00:00:00
abstract：:The myocyte enhancer factor 2C (MEF2C) is a member of the MEF2 family of transcription factors, involved in skeletal muscle development. In this study we report the cDNA sequence and isolate the 5' upstream region of the mef2c gene from porcine genomic DNA using PCR-based GenomeWalker. The open reading frame of porcin...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-010-0609-x
更新日期：2011-10-01 00:00:00
abstract：:Spata34 is a testis-specific-expressed gene which exerts diverse functions in testis development. This study intends to examine the expression profiles of Spata34 in postnatal rat testis, and explore its potential roles in cell proliferation in vitro. We found that the mRNA and protein expression levels of Spata34 wer...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-018-4439-6
更新日期：2018-12-01 00:00:00
abstract：:The lily-of-the-valley Convallaria (Asparagaceae) consists of three herbaceous perennial species. The plants are commonly found in northern hemisphere, and are best-known for their ornamental and pharmaceutical value. In order to assess the genetic structure, diversity and demographic history of Convallaria species, 1...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-020-05376-9
更新日期：2020-04-01 00:00:00
abstract：:In vivo and in vitro expressed N-terminal sequence of EWS (EAD) and hsRPB7 (subunit of human RNA polymerase II) were probed for protein-protein interactions using pull-down assays. In result, it was found that the proteins 57Z (residues 1-57 of EAD) and hsRPB7 interact in vitro forming a stable complex. The direct int...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-008-9308-2
更新日期：2009-07-01 00:00:00
abstract：:The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies ha...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-010-9955-y
更新日期：2011-06-01 00:00:00
abstract：:The conserved M2 protein of influenza A virus is considered as a promising candidate target for a broad-spectrum, recombinant influenza A vaccine. In the present study, the open reading frame (ORF) of avian influenza A/chicken/Iran/101/1998 (H9N2) M2 gene was amplified then cloned in pAED4, prokaryotic expression vect...
journal_title：Molecular biology reports
pub_type： 杂志文章
doi：10.1007/s11033-009-9851-5
更新日期：2010-07-01 00:00:00
