Phenol oxidase is a necessary enzyme for the silkworm molting which is regulated by molting hormone.

abstract：:Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence, this study evaluated the cardioprotective mechanism(s) of Morin against isoproterenol induced myocardial necrosis in rats. Male albino Wistar rats were divided ...

journal_title：Molecular biology reports

authors： Verma VK,Malik S,Narayanan SP,Mutneja E,Sahu AK,Bhatia J,Arya DS

更新日期：2019-02-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diagnoses seen by primary care providers and gastroenterologists. Proinflammatory cytokines interleukin (IL)-6 and IL-8 have been found increased in IBS patients. Cytokine gene single nucleotide polymorphisms (SNPs) of IL-8 and IL-10 have not be...

journal_title：Molecular biology reports

authors： Romero-Valdovinos M,Gudiño-Ramírez A,Reyes-Gordillo J,Martínez-Flores WA,Ramírez-Miranda ME,Maravilla P,Olivo-Díaz A

更新日期：2012-09-01 00:00:00

abstract：:The beta class of the carbonic anhydrase (CA) enzyme family has been found in plants, yeast, bacteria and algae, but not in animals. Also, little is known concerning the CAs of C. elegans. Genes possibly encoding beta-CAs were revealed by in silico analysis of the C. elegans genome. Amino acid sequence and 3D structur...

journal_title：Molecular biology reports

authors： Fasseas MK,Tsikou D,Flemetakis E,Katinakis P

更新日期：2010-07-01 00:00:00

abstract：:Molluscs are an extraordinarily diverse group of animals and to discriminate them based on one molecular marker/gene is very difficult because of the too fast or slow rate of nucleotide substitution. In the study, the tropomyosin cds (coding sequences) of 43 animal species were analyzed, the results of which suggested...

journal_title：Molecular biology reports

authors： Wang X,Li L,Xu F,Zhang G

更新日期：2011-10-01 00:00:00

abstract：:The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice. The tumor xenograft models were established and randomly assigned to 4 groups: control group, Endostar group (1.5 mg/kg day, once daily for 3 weeks), chemotherap...

journal_title：Molecular biology reports

authors： Chang L,Guo F,Lv Y,Wang Y,Huo B,Wang L,Liu W

更新日期：2013-01-01 00:00:00

abstract：:TopBP1 protein displays structural as well as functional similarities to BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expression of TopBP1 may lead to genomic instability and can have pathological consequences. In this study we aimed to investigate e...

journal_title：Molecular biology reports

authors： Forma E,Krzeslak A,Bernaciak M,Romanowicz-Makowska H,Brys M

更新日期：2012-07-01 00:00:00

abstract：:Osteocytic potentiality of human CD34+ stem cells explored in the present study by generating in vitro agarose gel 3D model to understand the bone ossification process. The G-CSF and IL-3 mobilized human CD34+ stem cells isolated apheretically from donor peripheral blood and purity of the cells was assessed by FACS an...

journal_title：Molecular biology reports

authors： Srikanth L,Sunitha MM,Kumar PS,Chandrasekhar C,Vengamma B,Sarma PV

更新日期：2016-11-01 00:00:00

abstract：:Our previous study revealed that CRB3 protein expression was reduced in clear cell renal cell carcinoma (ccRCC) and was associated with TNM stage, pathological grade, and poor prognosis of ccRCC. This study aimed to investigate if DNA methylation of CRB3 decreases its expression, subsequently leading to the progressio...

journal_title：Molecular biology reports

authors： Li P,Liu J,Li J,Liu P

更新日期：2019-08-01 00:00:00

abstract：:The human COX-2 promoter contains a direct repeat 1 (DR1) which was shown to confer responsiveness to PPARs. We found that in AN(3)CA and F9 cells, this hCOX-2 DR1 mediates responsiveness to all-trans-retinoic acid (tRA) or 9-cis-retinoic acid (9cRA), but this effect was suppressed by PPARδ. Truncated PPARδ lacking th...

journal_title：Molecular biology reports

authors： Han K,Moon I,Lim HJ

更新日期：2011-02-01 00:00:00

abstract：:This meta-analysis was performed to assess the relationships between the PON1 Q192R (rs662 T>C) polymorphism and the clinical outcome of antiplatelet treatment after percutaneous coronary intervention (PCI). A range of electronic databases were searched: Web of Science (1945-2013), the Cochrane Library Database (Issue...

journal_title：Molecular biology reports

authors： Li P,Bu SH,Lu XT,Li LX,Xu AJ,Tang YN,Zhang J

更新日期：2014-09-01 00:00:00

abstract：:Low levels of coenzyme Q10 (CoQ10) have been reported in the circulation of patients with breast cancer, particularly in metastatic features. Our objective was to study the correlation between plasma levels of CoQ10 and the tumoral expression levels of AMPK, PFKFB3, VEGF, and VEGFR2. This study was a part of consecuti...

journal_title：Molecular biology reports

authors： Abdi S,Montazeri V,Garjani A,Shayanfar A,Pirouzpanah S

更新日期：2020-04-01 00:00:00

abstract：:We performed PCR of many DNA fragments of 6-32 nucleotides in length. Some of the fragments expanded into kilobase lengths even in the absence of the complementary strand. The dramatic expansion was observed for (CA)8, (TG)8, (CA)4, (CA)6, (CA)12, (TG)4, (TG)6, (TG)12, (TC)10, (GA)10 and other single strands. Similar ...

journal_title：Molecular biology reports

authors： Reichová N,Kypr J

更新日期：2003-09-01 00:00:00

abstract：:A double-stranded RNA-specific nuclease (ds RNase) has been isolated and partially purified from human placenta by DEAE-cellulose and DNA-cellulose column chromatography. Denatured DNA-cellulose retained most of the single-stranded RNA-specific nuclease (ss RNase) activity, whereas the ds RNase came out in the void vo...

journal_title：Molecular biology reports

authors： Kalyanaraman S,Maran A,Shanmugam G

更新日期：1983-08-01 00:00:00

abstract：:In the present study, we investigated the differentially expressed proteins associated with ulcerative colitis (UC) using proteomic methods. Two-dimensional electrophoresis (2-DE) technology was performed to separate the total proteins of ulcerative tissues from those of the normal tissues of UC patients. PDQuest soft...

journal_title：Molecular biology reports

authors： Li N,Wang X,Zhang Y,Zhai J,Zhang T,Wei K

更新日期：2012-05-01 00:00:00

abstract：:The 1,044 bp endo-1,4-β-xylanase gene of a hyperthermophilic Eubacterium, "Thermotoga petrophila RKU 1" (T. petrophila) was amplified, from the genomic DNA of donor bacterium, cloned and expressed in mesophilic host E. coli strain BL21 Codon plus. The extracellular target protein was purified by heat treatment followe...

journal_title：Molecular biology reports

authors： ul Haq I,Hussain Z,Khan MA,Muneer B,Afzal S,Majeed S,Akram F

更新日期：2012-07-01 00:00:00

abstract：:In this study we are presenting the development of technetium-99m (99mTc) labeled ibuprofen for the imaging of aseptic inflammation. 99mTc-Ibuprofen complex was developed by optimizing the radiolabeling conditions such as reaction time, ligand and reducing agent concentration, pH, reaction time and temperature. Follow...

journal_title：Molecular biology reports

authors： Khan NU,Naqvi SAR,Sohail H,Roohi S,Jamal MA

更新日期：2019-06-01 00:00:00

abstract：:Start codon targeted (SCoT) polymorphic markers were used to assess genetic relationships among 64 grape varieties. Seventeen informative primers were selected from 36 SCoT primers based on their ability to produce clear and repeatable polymorphic and unambiguous bands among the varieties. A total of 131 bands were pr...

journal_title：Molecular biology reports

authors： Guo DL,Zhang JY,Liu CH

更新日期：2012-05-01 00:00:00

abstract：:Common bean is gaining acceptance as one of the most valuable major food consumed worldwide owing to innumerable nutritional and therapeutic benefits. Comparatively less productivity in underdeveloped countries encouraged us to proceed for QTL mining of yield traits in common bean. Heretofore, multiple yield associate...

journal_title：Molecular biology reports

authors： Gupta N,Zargar SM,Singh R,Nazir M,Mahajan R,Salgotra RK

更新日期：2020-09-01 00:00:00

abstract：:To determine the plasma lipid and lipoprotein profiles and their possible association with the type of β-thalassemia mutation we studied 103 major β-thalassemia patients including 71 children and 32 young adults compared to 102 healthy subjects consisted of 90 children and 12 young healthy adults. The plasma lipid and...

journal_title：Molecular biology reports

authors： Madani H,Rahimi Z,Manavi-Shad M,Mozafari H,Akramipour R,Vaisi-Raygani A,Rezaei M,Malek-Khosravi S,Shakiba E,Parsian A

更新日期：2011-04-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:The small molecules already existing on the earth can be assembled to biological macromolecules in the presence of the suitable tool. A workman must sharpen his tools if he is to do his work well. The tool must be specific, delicate and automatic. Obviously, it is enzyme. Therefore, to explore the origin of life we mu...

journal_title：Molecular biology reports

authors： Yin X,Yuan Z

更新日期：2009-02-01 00:00:00

abstract：:Flavonoids are the main flavor components and functional ingredients in tea, and the shikimic acid pathway is considered as one of the most important pathways in flavonoid biosynthesis, but little was known about the function of regulatory genes in the metabolism phenolic compounds in tea plant (Camellia sinensis), es...

journal_title：Molecular biology reports

authors： Zhu XJ,Zhao Z,Xin HH,Wang ML,Wang WD,Chen X,Li XH

更新日期：2016-10-01 00:00:00

abstract：:Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. The aim of this study was to quantify the expression of angiogenic (VEGF, HIF-1α, Angiopiotein-2) and anti-angiogenic (endostatin, angiostatin and Thrombospondin-1) factors and to discern their cl...

journal_title：Molecular biology reports

authors： Sharma BK,Srinivasan R,Kapil S,Singla B,Chawla YK,Chakraborti A,Saini N,Duseja A,Das A,Kalra N,Dhiman RK

更新日期：2013-10-01 00:00:00

abstract：:The majority of familial breast and ovarian cancers arise from mutations in the BRCA1 and BRCA2 genes. Amplification at the 11q13.5 locus is commonly observed in breast and ovarian cancers. In 2003, Hughes-Davies et al. identified a novel gene (EMSY) at this locus which binds BRCA2 within a region deleted in some canc...

journal_title：Molecular biology reports

authors： Altinisik J,Karateke A,Coksuer H,Ulutin T,Buyru N

更新日期：2011-01-01 00:00:00

abstract：:Here, we document changes in cell motility and organization of the contractile apparatus of human umbilical cord Wharton's jelly mesenchymal stem cells (MSCWJ-1) in the process of replicative senescence. Colocalization dynamics of F-actin and actin-binding proteins (myosin-9, α-actinin-4, RhoA) were examined in the MS...

journal_title：Molecular biology reports

authors： Bobkov D,Polyanskaya A,Musorina A,Lomert E,Shabelnikov S,Poljanskaya G

更新日期：2020-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) incidence is fast-growing especially in countries highly prevalent with viral hepatitis. Its poor prognosis has driven the research toward the discovery of sensitive markers for early detection. We investigated the usefulness of serum Transforming growth factor-beta1 (TGF-β1), Glypican-3...

journal_title：Molecular biology reports

authors： Ibrahim GH,Mahmoud MA,Aly NM

更新日期：2013-12-01 00:00:00

abstract：:Body measurement and meat quality traits which play important roles in the assessment of productivity and economy in cattle were influenced by genes and environmental factors. Latest studies showed that LYR motif containing 1 (LYRM1) may be involved in influencing fatness deposition in animals. The objective of this s...

journal_title：Molecular biology reports

authors： Li Y,Gao J,Yang N,Fu C,Cheng G,Wang H,Zan L

更新日期：2013-02-01 00:00:00

abstract：:Vascular endothelial growth factor B (VEGF-B) was reported to be angiogenic, and it was considered as a neuroprotective agent in mouse retinal ganglion cells following optic nerve crush. Thus, it was necessary to investigate whether VEGF-B contributes to the process of retinal and choroidal neovascularization. We aime...

journal_title：Molecular biology reports

authors： Zhang GH,Qin R,Zhang SH,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:Recent evidence supports a role of Toll-like receptor (TLR) signaling in the development of atherosclerotic lesions. It was confirmed that the presence of functional TLR4 promotes a proinflammatory phenotype and proliferation of vascular smooth muscle cells (VSMCs). Here we tested whether designed TLR4 small interferi...

journal_title：Molecular biology reports

authors： Li H,Xu H,Liu S

更新日期：2011-02-01 00:00:00

abstract：:Transcriptional factors are the major regulators of plant signaling pathways in response to environmental stresses i.e., drought, salinity and cold. Hereby, the GhMYB108-like was characterized to determine whether it regulate these stresses. The GhMYB108-like cDNA consisted of 1107 base pairs (bp) with 807 open readin...

journal_title：Molecular biology reports

authors： Ullah A,Ul Qamar MT,Nisar M,Hazrat A,Rahim G,Khan AH,Hayat K,Ahmed S,Ali W,Khan A,Yang X

更新日期：2020-03-01 00:00:00