DNA methylation of CRB3 is a prognostic biomarker in clear cell renal cell carcinoma.

abstract：:Ribosomal protein S3 (RPS3) is a component of the 40S ribosomal subunit. It is known to function in ribosome biogenesis and as an endonuclease. RPS3 has been shown to be over expressed in colon adenocarcinoma but its role in colon cancer is still unknown. In this study, we aim at determining the expression levels of R...

journal_title：Molecular biology reports

authors： Alam E,Maaliki L,Nasr Z

更新日期：2020-08-01 00:00:00

abstract：:One mutant transgenic line displaying homeotic conversion of sepals to petals with other phenotypic aberrations was selected and characterized at molecular level. The increased transcript level of gene encoding anthocyanidin synthase and petal specific class B genes, GLOBOSA and DEFECIENS in sepals of mutant line may ...

journal_title：Molecular biology reports

authors： Mahajan M,Yadav SK

更新日期：2014-02-01 00:00:00

abstract：:It is necessary that genetic markers or biomarkers can be used to predict resistance towards a wide range of infectious diseases. In the present study, we estimated the potential markers and measured their relationship with heritabilities of a wide range of immune traits. Polymorphisms in exon 13 of Mx1, intron 25 of ...

journal_title：Molecular biology reports

authors： Wang SJ,Liu WJ,Sargent CA,Zhao SH,Liu HB,Liu XD,Wang C,Hua GH,Yang LG,Affara NA,Zhang SJ

更新日期：2012-03-01 00:00:00

abstract：:India has a rich heritage of rearing cattle where farmers selected native cattle suitable to their local agro-ecological conditions for centuries. It is reflected in 50 indigenous breeds of cattle, besides many lesser known populations not explored so far. It is the need of the hour to characterize such populations to...

journal_title：Molecular biology reports

authors： Sharma R,Ahlawat S,Sharma H,Bhagat RL,Singh PK,Tantia MS

更新日期：2020-08-01 00:00:00

abstract：:Cordyceps sinensis (CS) is an entomogenous fungus used as a tonic food and Chinese medicine to replenish health. This study investigated the protective effects of CS in rats post-renal ischemia-reperfusion (I/R) sequence by analyzing the influence on stromal cell-derived factor-1α (SDF-1α and chemokine (C-X-C motif) r...

journal_title：Molecular biology reports

authors： Wang HP,Liu CW,Chang HW,Tsai JW,Sung YZ,Chang LC

更新日期：2013-03-01 00:00:00

abstract：:Identifying patients at high risk of metastasis is a major challenge in lung adenocarcinoma (ADC) therapy, therefore discovery of noninvasive biomarkers and therapeutic targets is urgent. We found significant differences between the secretomes of differentially expressed proteins in lung ADC cell lines, clinical tissu...

journal_title：Molecular biology reports

authors： Liu Z,Gao Y,Hao F,Lou X,Zhang X,Li Y,Wu D,Xiao T,Yang L,Li Q,Qiu X,Wang E

更新日期：2014-11-01 00:00:00

abstract：:Recent Genome-Wide Association Studies have identified several single nucleotide polymorphisms (SNPs) associated with breast cancer (BC) among women of Asian, European, and African-American ancestry. Nevertheless, the contribution of these variants in the South American population is unknown. Furthermore, there is lit...

journal_title：Molecular biology reports

authors： Elematore I,Gonzalez-Hormazabal P,Reyes JM,Blanco R,Bravo T,Peralta O,Gomez F,Waugh E,Margarit S,Ibañez G,Romero C,Pakomio J,Roizen G,Di Capua GA,Jara L

更新日期：2014-06-01 00:00:00

abstract：:The aim of this study was to elucidate the effects of sex hormones on activity of the ABCG2 promoter in different cell lines. T47D cells and BeWo cells were used as models for ABCG2-expressing cell lines, and luciferase assays using ABCG2 promoter-luciferase constructs were performed. It was shown that progesterone in...

journal_title：Molecular biology reports

authors： Yasuda S,Kobayashi M,Itagaki S,Hirano T,Iseki K

更新日期：2009-09-01 00:00:00

abstract：:HSG1 (Heat shock-induced gene 1) is one of the high-temperature-induced proteins in grapevine. Sequence analysis has demonstrated that HSG1 is a grape Bcl-2-associated athanogene (BAG) that contains IQ and BAG domains in its sequence. HSG1 expression was not detected in leaves without heat treatment, while tendrils, s...

journal_title：Molecular biology reports

authors： Kobayashi M,Takato H,Fujita K,Suzuki S

更新日期：2012-04-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:The swine fatty acid binding protein gene (FABP3) has been screened with 4 primer sets for 270 purebred Yorkshire pigs from National Institute of Animal Science. The selection of primers was based on the swine cDNA sequence (AJ416019), and primer sets (FABP3-2 and FABP3-3) amplified target segments in real time PCR to...

journal_title：Molecular biology reports

authors： Cho KH,Kim MJ,Jeon GJ,Chung HY

更新日期：2011-03-01 00:00:00

abstract：:Previous report showed that Estrogen related receptor α (ERRα) knockout mice had a significant reduction in adipose tissue deposition. Although it was reported that ERRα could promote adipogenesis in several immortalized preadipocytes cell lines, the mechanism behind which is still unclear to date. Besides, the expres...

journal_title：Molecular biology reports

authors： Ju D,He J,Zhao L,Zheng X,Yang G

更新日期：2012-03-01 00:00:00

abstract：:The MinION is a miniaturized high-throughput next generation sequencing platform of novel conception. The use of nucleic acids derived from formalin-fixed paraffin-embedded samples is highly desirable, but their adoption for molecular assays is hurdled by the high degree of fragmentation and by the chemical-induced mu...

journal_title：Molecular biology reports

authors： Vacca D,Cancila V,Gulino A,Lo Bosco G,Belmonte B,Di Napoli A,Florena AM,Tripodo C,Arancio W

更新日期：2018-02-01 00:00:00

abstract：:Type 2 diabetes is one of the most prevalent diseases, which increases resistance to insulin in target tissues. The measurement of miRNAs quantity is a molecular approach for diagnosis of diabetes. miRNAs are small non-coding RNA strings of 21-23 long nucleotides that act as inhibitors in proteins translation. Several...

journal_title：Molecular biology reports

authors： Andoorfar S,Hosseini Tafreshi SA,Rezvani Z

更新日期：2019-10-01 00:00:00

abstract：:microRNAs are short, non-coding RNAs, that exert a posttranscriptional control on protein synthesis by mRNA interference. They are involved in normal and pathological embryologic development, as well as in adult life pathology, from myocardial infarction to cancer. There are several brain-specific species of microRNA,...

journal_title：Molecular biology reports

authors： Enciu AM,Popescu BO,Gheorghisan-Galateanu A

更新日期：2012-03-01 00:00:00

abstract：:Studies of the refractive properties of Gramicidin A in absolute ethanol and in ethanol water mixtures showed that this peptide in solution undergoes a conformational transition resulting in species with different refractivity. Accordingly, the folded form of this peptide shows a lower specific refractive index increm...

journal_title：Molecular biology reports

authors： Derechin M,Jordan BE

更新日期：1975-07-01 00:00:00

abstract：:Emergence of MDR 'superbugs' inflamed a severe sense of urgency amongst scientists aiming at the discovery of novel potential drug molecules. Bacteria of the genus Streptomyces are really worth investigating for their immense potential to produce natural compounds of pharmaceutical importance. In the present study, th...

journal_title：Molecular biology reports

authors： Kumar P,Chauhan A,Kumar M,Kuanr BK,Solanki R,Kapur MK

更新日期：2020-09-01 00:00:00

abstract：:The interaction between ovalbumin (OVA) and three purine alkaloids (caffeine, theophylline and diprophylline) was investigated by the aid of intrinsic and synchronous fluorescence, ultraviolet-vis absorbance, resonance light-scattering spectra and three-dimensional fluorescence spectra techniques. Results showed that ...

journal_title：Molecular biology reports

authors： Wang RQ,Yin YJ,Li H,Wang Y,Pu JJ,Wang R,Dou HJ,Song CJ,Wang RY

更新日期：2013-04-01 00:00:00

abstract：:Bud dormancy in perennial plants adapts to environmental and seasonal changes. Bud dormancy is of ecological interest because it affects forest population growth characteristics and is of economical interest because it impacts wood production levels. To understand Pinus sylvestris L. var. mongolica litv. bud-dormancy ...

journal_title：Molecular biology reports

authors： Bi YD,Wei ZG,Shen Z,Lu TC,Cheng YX,Wang BC,Yang CP

更新日期：2011-02-01 00:00:00

abstract：:The majority of familial breast and ovarian cancers arise from mutations in the BRCA1 and BRCA2 genes. Amplification at the 11q13.5 locus is commonly observed in breast and ovarian cancers. In 2003, Hughes-Davies et al. identified a novel gene (EMSY) at this locus which binds BRCA2 within a region deleted in some canc...

journal_title：Molecular biology reports

authors： Altinisik J,Karateke A,Coksuer H,Ulutin T,Buyru N

更新日期：2011-01-01 00:00:00

abstract：:Approximately 90% of patients with advanced breast cancer develop bone metastases; an event that results in severe decrease of quality of life and a drastic deterioration in prognosis. Therefore, to increase the survival of breast cancer patients, the development of new therapeutic strategies to impair metastatic proc...

journal_title：Molecular biology reports

authors： Vashum Y,Premsingh R,Kottaiswamy A,Soma M,Padmanaban A,Kalaiselvan P,Samuel S

更新日期：2020-12-08 00:00:00

abstract：:Low levels of coenzyme Q10 (CoQ10) have been reported in the circulation of patients with breast cancer, particularly in metastatic features. Our objective was to study the correlation between plasma levels of CoQ10 and the tumoral expression levels of AMPK, PFKFB3, VEGF, and VEGFR2. This study was a part of consecuti...

journal_title：Molecular biology reports

authors： Abdi S,Montazeri V,Garjani A,Shayanfar A,Pirouzpanah S

更新日期：2020-04-01 00:00:00

abstract：:Development of a rapid and accurate quantification method for the detection of microRNAs (miRNAs) has been desired, in particular, when they are differently expressed in normal and pathological conditions. However, various methods for the quantification of small non-coding RNAs as well as miRNAs have been described. T...

journal_title：Molecular biology reports

authors： Mohammadi-Yeganeh S,Paryan M,Mirab Samiee S,Soleimani M,Arefian E,Azadmanesh K,Mostafavi E,Mahdian R,Karimipoor M

更新日期：2013-05-01 00:00:00

abstract：:In plants, stomata play a pivotal role in the regulation of gas exchange and are distributed throughout the aerial epidermis. SDD1, a gene isolated from Arabidopsis thaliana has been demonstrated to specialize in stomatal density and distribution. In our present study, a comprehensive survey of global gene expression ...

journal_title：Molecular biology reports

authors： Xiao Y,Yu X,Chen J,Di P,Chen W,Zhang L

更新日期：2010-02-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diagnoses seen by primary care providers and gastroenterologists. Proinflammatory cytokines interleukin (IL)-6 and IL-8 have been found increased in IBS patients. Cytokine gene single nucleotide polymorphisms (SNPs) of IL-8 and IL-10 have not be...

journal_title：Molecular biology reports

authors： Romero-Valdovinos M,Gudiño-Ramírez A,Reyes-Gordillo J,Martínez-Flores WA,Ramírez-Miranda ME,Maravilla P,Olivo-Díaz A

更新日期：2012-09-01 00:00:00

abstract：:The transforming growth factor-β (TGF-β) signaling pathway is conserved across animals, and knowledge of its roles during the molt cycle in crustaceans is presently very limited. This study investigates the roles of the TGF-β receptor in molting-related muscle growth in Eriocheir sinensis. Using the RT-PCR and RACE te...

journal_title：Molecular biology reports

authors： Tian Z,Peng H,Deng W,Jiao C

更新日期：2020-01-01 00:00:00

abstract：:In autoimmune disease body's own immune system knows healthy cells as undesired and foreign cells. Over 80 types of autoimmune diseases have been recognized. Currently, at clinical practice, treatment strategies for autoimmune disorders are based on relieving symptoms and preventing difficulties. In other words, there...

journal_title：Molecular biology reports

authors： Rad F,Ghorbani M,Mohammadi Roushandeh A,Habibi Roudkenar M

更新日期：2019-02-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs24...

journal_title：Molecular biology reports

authors： Sun R,Huang Y,Zhang H,Liu R

更新日期：2013-11-01 00:00:00

abstract：:Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) are common syndromes characterized by diffuse, acute injury to the alveolar epithelium and pulmonary vascular endothelial cells, with high mortality rate for there are no effective pharmacological therapies. Peroxisome proliferators-activated recept...

journal_title：Molecular biology reports

authors： Xiao B,Xu J,Wang G,Jiang P,Fang F,Huang J,Wang J

更新日期：2011-11-01 00:00:00

abstract：:Growing data supported that epigenetic modifications, including altered DNA methylation have a potential role in the pathogenesis of autoimmune thyroid diseases (AITD). In the present study we aimed to investigate the methylation status of ICAM-1 gene promoter in patients with AITD. Forty patients with Graves' disease...

journal_title：Molecular biology reports

authors： Shalaby SM,Mackawy AMH,Atef DM,Atef RM,Saeed J

更新日期：2019-10-01 00:00:00