Abstract:
:Studies of the refractive properties of Gramicidin A in absolute ethanol and in ethanol water mixtures showed that this peptide in solution undergoes a conformational transition resulting in species with different refractivity. Accordingly, the folded form of this peptide shows a lower specific refractive index increment than the unfolded form. In addition, the occurrence of a strong pressure dependence of the transition is documented.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Derechin M,Jordan BEdoi
10.1007/BF00357540subject
Has Abstractpub_date
1975-07-01 00:00:00pages
107-12issue
2eissn
0301-4851issn
1573-4978journal_volume
2pub_type
杂志文章abstract::The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies ha...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-9955-y
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abstract::The binding of acridine orange and ethidium bromide to rat liver chromatin increases by 30% one hour after partial hepatectomy, returns to the control level by the second hour and increases again by the sixth hour. The changes described were found in investigations carried out on whole cells, on isolated nuclei, and o...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00777513
更新日期:1978-10-16 00:00:00
abstract::Insect molting is an important developmental process of metamorphosis, which is initiated by molting hormone. The molting process includes the activation of dermal cells, epidermal cells separation, molting fluid secretion, the formation of new epidermis and old epidermis excoriation etc. Polyphenol oxidases (PPOs), d...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2428-8
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abstract::Random amplified polymorphic DNA (RAPD) and microsatellite markers were applied to evaluate the genetic variation in endemic and endangered yellow catfish, Horabagrus brachysoma sampled from three geographic locations of Western Ghat, South India river systems. In RAPD, of 32 10-mer RAPD primers screened initially, 10...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-008-9381-6
更新日期:2009-09-01 00:00:00
abstract::HMG proteins were extracted with 5% PCA or 0.35 M NaCl from whole tissue, nuclei or chromatin of the liver of young (19 weeks) and old (118 weeks) male rats. They were resolved on acetic acid-urea polyacrylamide gel. The electrophoretic patterns of the major HMG proteins 1, 2, 14 and 17 of both ages are similar. The i...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00369896
更新日期:1991-02-01 00:00:00
abstract::Genetic analyses have contributed to improvements of economically important traits derived from adipose tissue such as fatty acid composition in beef. Elongation of very long chain fatty acids (ELOVL) genes encode for the enzymes that play an important role in elongation of long-chain fatty acids. In this study, we ai...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2398-x
更新日期:2013-04-01 00:00:00
abstract::Proto-oncogen Ahi-1 is closely related to a lot of human and mouse diseases. Ahi-1 mutation will lead to leukemia in mice and Joubert syndrome in human beings. We have cloned the full cDNA sequence of Ahi-1 homologous in zebrafish, and RT-PCR results of ZAhi-1 in different tissues reveal that ZAhi-1 expressed highest ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-006-0005-8
更新日期:2006-06-01 00:00:00
abstract::Rheumatoid arthritis (RA) is considered as a long-term autoimmune disorder. Gene polymorphism and oxidative stress might be involved in the pathogenesis of the disease. We aimed to determine the association between PON-1L55M polymorphism and its effects on inflammatory markers such as anti-cytroline circulated-peptide...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-018-4530-z
更新日期:2019-02-01 00:00:00
abstract::The sterol regulatory element binding factor 1 (SREBP1) gene plays an important role in the biosynthesis of fatty acids. The aim of this study was to investigate the association between SNPs within SREBP1 gene and fatty acid composition of muscle fat and marbling score in a commercial population of Korean cattle. Amon...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2055-4
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abstract::Cardiomyocytes possess the ability to respond to mechanical stimuli by reprogramming their gene expression. This study investigated the effects of different loading protocols on signaling and expression responses of myogenic, anabolic, inflammatory, atrophy and pro-apoptotic genes in cardiomyocyte-like H9C2 cells. Dif...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-06112-z
更新日期:2021-01-04 00:00:00
abstract::In a meritorious effort H. de Rothschild compiled in 1899 all publications on mammary gland development and milk--a grand total of 8375 [1]. In the preface to this publication Duclaux states: 'Such a discrepancy between the tremendous efforts and the paltriness of the results--hundreds of scientists and thousands of r...
journal_title:Molecular biology reports
pub_type: 杂志文章,评审
doi:10.1023/a:1006851531360
更新日期:1997-08-01 00:00:00
abstract::Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3489-7
更新日期:2014-09-01 00:00:00
abstract::20S proteasomes are large (700 kDa) proteinase complexes which form the central catalytic core of larger complexes (26S proteasomes or PA28-20S complexes) formed by association with regulatory particles. These larger complexes are involved in diverse regulatory processes in the cell including cyclin breakdown, proteol...
journal_title:Molecular biology reports
pub_type: 杂志文章,评审
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更新日期:1999-04-01 00:00:00
abstract::There is an increasing body of evidence that a brief exposure to anesthesia induces ischemic tolerance in rat brain (anesthetic preconditioning). However, it is unknown whether preconditioning with sevoflurane, a commonly used volatile anesthetic in current clinical practice, produces a delayed window of neuroprotecti...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1290-4
更新日期:2012-05-01 00:00:00
abstract::The immunity and health status of ornamental fish is an important aspect, as they are kept in a confined environment and various stressful conditions which lead to depletion of overall colourful appearance and mortality. The carotenoids can act as immunity boosters in captive aquarium system and may be supplemented in...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05027-8
更新日期:2019-12-01 00:00:00
abstract::We have previously shown that angiotensin-converting enzyme (ACE) gene D allele is an independent risk factor for early onset coronary artery disease (CAD). Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. Regarding the high...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1027-4
更新日期:2012-03-01 00:00:00
abstract::Differential display (DD) is a novel PCR-based technique, very commonly used to study differentially expressed genes at the mRNA level. In this paper we report a modified version of this technique that we have used to study the differences between the mRNA population from brain tissue of adult and old rats. We have mo...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-006-9010-1
更新日期:2007-03-01 00:00:00
abstract::DNA repair capacity (DRC) can be altered based on sequence variations in DNA repair genes, which may result in cancer susceptibility. The current study was to evaluate the association between genetic polymorphisms, including associated haplotypes of xeroderma pigmentosum complementary group D (XPD), and individual sus...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0258-0
更新日期:2011-03-01 00:00:00
abstract::Low levels of coenzyme Q10 (CoQ10) have been reported in the circulation of patients with breast cancer, particularly in metastatic features. Our objective was to study the correlation between plasma levels of CoQ10 and the tumoral expression levels of AMPK, PFKFB3, VEGF, and VEGFR2. This study was a part of consecuti...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05310-z
更新日期:2020-04-01 00:00:00
abstract::The glutathione S-transferase (GST) family of enzymes is known to play a pivotal role in phase II of biotransformation of xenobiotics, environmental carcinogens and pharmacological drugs. The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstru...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0287-8
更新日期:2011-03-01 00:00:00
abstract::Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05042-9
更新日期:2019-12-01 00:00:00
abstract::Methicillin resistant Staphylococcus aureus (MRSA) is one of the challenging bacterial pathogen due to its acquired resistance to the β lactam antibiotics. The Sortase A is an enzyme of Gram-positive bacteria including S. aureus to anchor surface proteins to the cell wall. Sortase A is well studied enzyme and consider...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3384-2
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abstract::Blood and liver from curimbata (Prochilodus lineatus) acclimated at pH 4.5, 7.0 and 8.0 and at 20 and 30 °C were exposed in vitro to different concentrations of copper (Cu): 98 ± 0.8 μg Cu L-1 at pH 4.5 and 16 ± 0.2 μg Cu L-1 at pH 8.0 at 20 °C; 88 ± 0.8 μg Cu L-1 at pH 4.5 and 14 ± 0.5 μg Cu L-1 at pH 8.0 at 30 °C an...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-04944-y
更新日期:2019-10-01 00:00:00
abstract::Berberine (BBR), an effective compound of Chinese traditional herbal medicine, has preventive effects on diabetes and its complications. In this study, we investigated the therapeutic effects and underlying molecular mechanisms of BBR in rats with high-fat diet and streptozotocin (STZ)-induced diabetic nephropathy mod...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2321-5
更新日期:2013-03-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3386-0
更新日期:2014-08-01 00:00:00
abstract::The phosphoenolpyruvate (PEP) carboxylase is regulated at the levels of transcription and post-translation in C4 plants in light and abundantly accumulates in leaf mesophyll cells. We report here developmental and photosynthetic regulation of stably accumulated Bacillus thuringiensis δ-endotoxin under the control of P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0369-7
更新日期:2011-04-01 00:00:00
abstract::Our previous study revealed that CRB3 protein expression was reduced in clear cell renal cell carcinoma (ccRCC) and was associated with TNM stage, pathological grade, and poor prognosis of ccRCC. This study aimed to investigate if DNA methylation of CRB3 decreases its expression, subsequently leading to the progressio...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-04892-7
更新日期:2019-08-01 00:00:00
abstract::MicroRNAs (miRNAs) may play important roles in SLE, but genetic polymorphisms of miRNAs and their relationships with various autoantibodies present in SLE patients remain unclear. Here, we report that 213 SLE patients and 209 healthy individuals of Chinese had been taken into this case-control studies, which had been ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0252-6
更新日期:2011-03-01 00:00:00
abstract::The phenylalanine and the phenylalanyl-tRNAPhe binding sites on the subunits of phenylalanyl-tRNA synthetase from E. coli MRE-600 were localized using p-azidoanilidate of [14C]phenylalanine and N-bromoacetyl-[14C]phenylalanyl-tRNAPhe. The phenylalanine recognizing site was shown to be situated on the alpha subunit of ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00778515
更新日期:1982-03-31 00:00:00
abstract::F-box proteins play important roles in the regulation of various developmental processes in plants. Approximately 1796 F-box genes have been identified in the wheat genome, but details of their functions remain unknown. Moreover, not much was known about the roles of kelch repeat domain-containing F-box genes (TaKFBs)...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05210-x
更新日期:2020-02-01 00:00:00