Effects of selected genetic polymorphisms in xeroderma pigmentosum complementary group D on gastric cancer.

abstract：:Adipocyte death is important in obesity development. Understanding and prevention of adipocyte deaths may be a molecular approach in the treatment. In the study, we aimed to understand role of Niban gene, which acts as an anti-apoptotic molecule as a response to stress conditions, in adipocytes. 3T3-L1 adipocytes were...

journal_title：Molecular biology reports

authors： Cevik M,Gunduz MK,Deliorman G,Susleyici B

更新日期：2020-12-01 00:00:00

abstract：:Putatively functional polymorphisms of one-carbon and xenobiotic metabolic pathways influence susceptibility for wide spectrum of diseases. The current study was aimed to explore gene-gene interactions among these two metabolic pathways in four diseases i.e. breast cancer, systemic lupus erythematosus (SLE), coronary ...

journal_title：Molecular biology reports

authors： Naushad SM,Vijayalakshmi SV,Rupasree Y,Kumudini N,Sowganthika S,Naidu JV,Ramaiah MJ,Rao DN,Kutala VK

更新日期：2015-07-01 00:00:00

abstract：:A chromosomal fragment containing purA, the nearest marker from the replication origin of the Bacillus subtilis chromosome, was highly purified as a complex containing at least proteins and being solubilized easily during cell lysis. The complex had a markedly higher sedimentation rate (70-120S) than the bulk of the s...

journal_title：Molecular biology reports

authors： Yamaguchi K,Yoshikawa H

更新日期：1976-07-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:Here, we document changes in cell motility and organization of the contractile apparatus of human umbilical cord Wharton's jelly mesenchymal stem cells (MSCWJ-1) in the process of replicative senescence. Colocalization dynamics of F-actin and actin-binding proteins (myosin-9, α-actinin-4, RhoA) were examined in the MS...

journal_title：Molecular biology reports

authors： Bobkov D,Polyanskaya A,Musorina A,Lomert E,Shabelnikov S,Poljanskaya G

更新日期：2020-05-01 00:00:00

abstract：:The lysyl oxidase-like 2 (LOXL2) protein is a human paralogue of lysyl oxidase (LOX) that functions as an amine oxidase for formation of lysine-derived cross-links found in collagen and elastin. In addition to the C-terminal domains characteristic to the LOX family members, LOXL2 contains four scavenger receptor cyste...

journal_title：Molecular biology reports

authors： Kim YM,Kim EC,Kim Y

更新日期：2011-01-01 00:00:00

abstract：:The round-leaf sundew (Drosera rotundifolia L.) is a carnivorous plant expressing a wide range of chitinolytic enzymes playing role in many different processes. In this study the intact plants were analyzed for the presence of chitinase transcripts and chitinolytic activities in different organs. In situ hybridization...

journal_title：Molecular biology reports

authors： Libantová J,Kämäräinen T,Moravcíková J,Matusíková I,Salaj J

更新日期：2009-05-01 00:00:00

abstract：:To determine the plasma lipid and lipoprotein profiles and their possible association with the type of β-thalassemia mutation we studied 103 major β-thalassemia patients including 71 children and 32 young adults compared to 102 healthy subjects consisted of 90 children and 12 young healthy adults. The plasma lipid and...

journal_title：Molecular biology reports

authors： Madani H,Rahimi Z,Manavi-Shad M,Mozafari H,Akramipour R,Vaisi-Raygani A,Rezaei M,Malek-Khosravi S,Shakiba E,Parsian A

更新日期：2011-04-01 00:00:00

abstract：:Adenylosuccinate lyase (ADSL) is a bifunctional enzyme acting in de novo purine synthesis and purine nucleotide recycling. In the present study, we have constructed a grass carp (Ctenopharyngodon idella) intestinal cDNA library that has over 2.3 × 10(5) primary clones. An expressed sequence tag (EST) of grass carp ade...

journal_title：Molecular biology reports

authors： Yuan T,Gu JR,Gu WB,Wu J,Ge SR,Xu H

更新日期：2011-03-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Increases of oxidatively modified protein in the cell have been associated with the aging process. Such an accumulation of damaged protein may be the result of increase in the rate of protein oxidation and/or decrease in the rate of degradation of oxidized protein. The multicatalytic proteinase or proteasome is known ...

journal_title：Molecular biology reports

authors： Conconi M,Friguet B

更新日期：1997-03-01 00:00:00

abstract：:Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. Direct exposure of human hepatoma cell line SMMC-7221 to hydrogen peroxide (H2O2) can induce apoptosis characterized by morphological evidence and fragmentation of DNA assayed by terminal deoxynucleotidyl transferase ...

journal_title：Molecular biology reports

authors： Huang C,Li J,Zheng R,Cui K

更新日期：2000-03-01 00:00:00

abstract：:Myocilin (MYOC) gene is expressed in many ocular tissues, including the trabecular meshwork, a specialized eye tissue essential in regulating intraocular pressure. Many mutations in MYOC have been detected in primary open-angle glaucoma (POAG). We investigated whether MYOC mutations contributed to the susceptibility t...

journal_title：Molecular biology reports

authors： Qu X,Zhou X,Zhou K,Xie X,Tian Y

更新日期：2010-01-01 00:00:00

abstract：:HIV/AIDS remains to be one of the killing diseases of mankind. Host genetic response is one of the factor which determine susceptibility to HIV and disease progression to AIDS. The aim of the present study was to evaluate the impact of ERCC2 Lyc ( 751 ) Gln (excision repair cross complementing rodent repair deficiency...

journal_title：Molecular biology reports

authors： Sobti RC,Berhane N,Mahdi SA,Kler R,Hosseini SA,Kuttiat V,Wanchu A

更新日期：2011-06-01 00:00:00

abstract：:An RNA polymerase III transcript, 7SK nuclear RNA, was found to bear sequence homology to the B2 class of highly repeated elements in the mouse genome. Northern blot hybridizations between the small RNAs and two B2 clones showed that only one of them (p49C8) hybridized to 7SK RNA. Both clones, however, hybridized to 4...

journal_title：Molecular biology reports

authors： Gallant J,Lovely J,Krause M

更新日期：1987-01-01 00:00:00

abstract：:Random amplified polymorphic DNA (RAPD) and microsatellite markers were applied to evaluate the genetic variation in endemic and endangered yellow catfish, Horabagrus brachysoma sampled from three geographic locations of Western Ghat, South India river systems. In RAPD, of 32 10-mer RAPD primers screened initially, 10...

journal_title：Molecular biology reports

authors： Abdul Muneer PM,Gopalakrishnan A,Musammilu KK,Mohindra V,Lal KK,Basheer VS,Lakra WS

更新日期：2009-09-01 00:00:00

abstract：:Tall fescue is a perennial cool-season grass with economic importance especially in temperate regions of the northern hemisphere. This study was done to assess the genetic diversity and population structure of 90 tall fescue populations and cultivars using ISSR and EST-SSR markers in order to categorize valuable popul...

journal_title：Molecular biology reports

authors： Shahabzadeh Z,Mohammadi R,Darvishzadeh R,Jaffari M

更新日期：2020-01-01 00:00:00

abstract：:Interindividual variability exists in statin lipid-lowering response, partially attributed to genetic factors. Organic anion-transporting polypeptide 1B1 (OATP1B1) encoded by SLCO1B1 gene (solute carrier organic anion transporter family member 1B1) facilitates hepatic uptake of simvastatin and atorvastatin. SLCO1B1 po...

journal_title：Molecular biology reports

authors： Giannakopoulou E,Ragia G,Kolovou V,Tavridou A,Tselepis AD,Elisaf M,Kolovou G,Manolopoulos VG

更新日期：2014-07-01 00:00:00

abstract：:Maize is one of the world's most important crops and a model for grass genome research. Long terminal repeat (LTR) retrotransposons comprise most of the maize genome; their ability to produce new copies makes them efficient high-throughput genetic markers. Inter-retrotransposon-amplified polymorphisms (IRAPs) were use...

journal_title：Molecular biology reports

authors： Ghonaim M,Kalendar R,Barakat H,Elsherif N,Ashry N,Schulman AH

更新日期：2020-03-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...

journal_title：Molecular biology reports

authors： Wang W,Gao J,Wang J,Liu C,Meng Y

更新日期：2012-12-01 00:00:00

abstract：:Proton beam therapy is widely used for treating brain tumor. Despite the efficacy of treatment, the use of this therapy has met some limitations associated with possible damage to normal brain tissues located beyond the tumor site. In this context, the exploration of the harmful effects of protons on the normal brain ...

journal_title：Molecular biology reports

authors： Abdullaev S,Bulanova T,Timoshenko G,Gaziev AI

更新日期：2020-06-01 00:00:00

abstract：:A cDNA encoding an O-methyltransferase (namely FGCOMT1) was identified from the medicinal plant Trigonella foenum-graecum L. The FGCOMT1 enzyme is a functional caffeic acid O-methyltransferase (COMT) and is localized in the cytosol. Kinetic analysis indicated that FGCOMT1 protein exhibited the highest catalyzing effic...

journal_title：Molecular biology reports

authors： Qin JC,Zhang YM,Lang CY,Yao YH,Pan HY,Li X

更新日期：2012-02-01 00:00:00

abstract：:Previous studies from our group have brought forward the concept of angiogenic regeneration during radiotherapy (RT), as a major cause of RT failure. This process was examined herein in rectal cancer patients undergoing preoperative chemo-radiotherapy. Out of 25 patients with stage II/III rectal adenocarcinoma, 15 had...

journal_title：Molecular biology reports

authors： Koukourakis MI,Koukourakis IM,Arelaki S,Kouroupi M,Domoxoudis S,Giatromanolaki A

更新日期：2019-04-01 00:00:00

abstract：:The purpose of this research is to identify the probable mitochondrial factor associated with cytoplasmic male sterility (cms) by comparative analysis of cms and its isogenic maintainer lines in stem mustards. Dramatic variations in the morphology of floral organs were observed in cms stem mustard. Mitochondrial atpA ...

journal_title：Molecular biology reports

authors： Yang JH,Huai Y,Zhang MF

更新日期：2009-02-01 00:00:00

abstract：:The Follicle stimulating hormone beta polypeptide (FSHβ) gene has been investigated as a candidate gene for litter size because of its role in maturation of small and medium follicles into ovulating large follicles. Genes coding follicle stimulating hormone have been found to have significant effects on litter size in...

journal_title：Molecular biology reports

authors： Magotra A,Naskar S,Das B,Ahmad T

更新日期：2015-02-01 00:00:00

abstract：:Autoantibodies to SS-A/Ro are among the most common found in sera of patients with systemic rheumatic diseases. These autoimmune diseases can affect various organ systems of the body and are variable in their manifestations and presentation. One of the autoimmune targets is the 60 kDa SS-A/Ro protein known to be assoc...

journal_title：Molecular biology reports

authors： Wang D,Buyon JP,Chan EK

更新日期：1996-01-01 00:00:00

abstract：:Silky Fowl is a natural mutant with hyperpigmentation of various internal tissues. Although the mechanism of hyperpigmentation remains unclear, recent studies have shown that the abnormal migration of melanoblast and the absence of environmental barrier molecules are responsible for the hyperpigmentation in Silky Fowl...

journal_title：Molecular biology reports

authors： Li Y,Zhu X,Yang L,Li J,Lian Z,Li N,Deng X

更新日期：2011-02-01 00:00:00

abstract：:The Phytophthora genus is composed, mainly, of plant pathogens. This genus belongs to the Oomycete class, also known as "pseudo-fungi", within the Chromista Kingdom. Phytophthora spp. is highlighted due to the significant plant diseases that they cause, which represents some of the most economically and cultural losse...

journal_title：Molecular biology reports

authors： de Andrade Lourenço D,Branco I,Choupina A

更新日期：2020-11-01 00:00:00

abstract：:Penicillin V is a bacteriolytic β-lactam antibiotic drug. In the present work, we investigated the inhibitory effect of Penicillin V on the activity of mushroom tyrosinase for the first time. The molecular mechanism for the inhibition of tyrosinase by Penicillin V was investigated by means of kinetics analysis, fluore...

journal_title：Molecular biology reports

authors： Dong X,Wang S,Xu L,Lin J,Xu X

更新日期：2020-02-01 00:00:00