Molecular cloning, characterization and expression analysis of adenylosuccinate lyase gene in grass carp (Ctenopharyngodon idella).

abstract：:Many case-control studies have investigated the role of TGF-β1 gene +869C/T promoter polymorphism in autoimmune diseases, but the results are inconsistent. To clarify this point, we performed a meta-analysis based on all available studies in Pubmed, Elsevier Science Direct, Google Searching, Chinese Biomedical Literat...

journal_title：Molecular biology reports

authors： Zhang L,Yan JW,Wang YX,Wan YN,Li JP,Liu P,Xu B,Wang BX,Peng WJ,Pan FM,Wang J

更新日期：2013-08-01 00:00:00

abstract：:Cold stress adversely affects the growth and development of seedling of spring soybean. Revealing responses in seedling to cold stress at proteomic level will help us to breed cold-tolerant spring soybean cultivars. In this study, to understand the responses, a proteomic analysis on the leaves of seedlings of one cold...

journal_title：Molecular biology reports

authors： Tian X,Liu Y,Huang Z,Duan H,Tong J,He X,Gu W,Ma H,Xiao L

更新日期：2015-03-01 00:00:00

abstract：:Overexpression of ATP-binding cassette (ABC) transporters causing multidrug resistance (MDR) in cancer cells is one of the major obstacles in cancer chemotherapy. The 5-FU resistant subclone (HL-60/5FU) of the human HL-60 promyelocytic leukemia cell line was selected by the conventional method of continuous exposure o...

journal_title：Molecular biology reports

authors： Długosz-Pokorska A,Pięta M,Janecki T,Janecka A

更新日期：2019-12-01 00:00:00

abstract：:CD40 signaling plays a critical role in the survival rate of gastric cancer patients. Tumour samples were collected from 73 patients with who were diagnosed as gastric cancer in general surgery department in the 1st affiliated hospital of Suzhou University between September 2002 and July 2003. All patients had not rec...

journal_title：Molecular biology reports

authors： Li R,Chen WC,Pang XQ,Tian WY,Wang WP,Zhang XG

更新日期：2012-09-01 00:00:00

abstract：:To investigate whether Annexin 1 can protect a retinal ganglion cells line (RGC-5) from apoptosis as induced by serum deprivation. Annexin 1 location in RGC-5 cells was determined using an indirect immunofluorescent assay. Expression of Annexin 1 in RGC-5 cultures deprived of serum for 0, 2 days was semi-quantified by...

journal_title：Molecular biology reports

authors： Sun J,Shao Z,Yang Y,Wu D,Zhou X,Yuan H

更新日期：2012-05-01 00:00:00

abstract：:The protease activity of gp63 from L. major was studied in relation to tunicamycin induced N-deglycosylation. It was found that after tunicamycin treatment, a N-deglycosylated product of gp63 with protease activity is present at the cell surface of Leishmania promastigote. ...

journal_title：Molecular biology reports

authors： Hernandez C,Manenti S,Hernandez AG

更新日期：1992-05-01 00:00:00

abstract：:Movement assisted by muscles forms the basis of various behavioural traits seen in Drosophila. Myogenesis involves developmental processes like cellular specification, differentiation, migration, fusion, adherence to tendons and neuronal innervation in a series of coordinated event well defined in body space and time....

journal_title：Molecular biology reports

authors： Dubey M,Ain U,Firdaus H

更新日期：2020-12-01 00:00:00

abstract：:Schistosomiasis, a disease caused by helminth parasites of genus Schistosoma. Its treatment intensively depends on single drug, praziquantel which increases the risk of development of drug-resistant parasite. Inhibitors of human HDAC are profoundly reported as novel anti-cancer drugs and used as new anit-parasitic age...

journal_title：Molecular biology reports

authors： Singh R,Pandey PN

更新日期：2015-03-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the main cause of blindness among the people in productive age. The purpose of this literature review is to highlight recent achievements in the genetics of diabetic retinopathy with particular focus on candidate gene studies. We...

journal_title：Molecular biology reports

authors： Priščáková P,Minárik G,Repiská V

更新日期：2016-12-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Mucopolysaccharidosis IV A (MPS IV A) is a lysosomal storage disease produced by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme. Although genotype-phenotype correlations have been reported, these approaches have not enabled to establish a complete genotype-phenotype correlation, and they ha...

journal_title：Molecular biology reports

authors： Olarte-Avellaneda S,Rodríguez-López A,Alméciga-Díaz CJ,Barrera LA

更新日期：2014-11-01 00:00:00

abstract：:The aim of this study was to determine whether the Fcγ receptors (FCGRs) polymorphisms confer susceptibility to periodontitis in ethnically different populations. We did a literature search using PubMed and Embase, and conducted a meta-analysis on the associations between the FCGR2A H131R (rs1801274), FCGR3A F158V (rs...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:The myocyte enhancer factor 2C (MEF2C) is a member of the MEF2 family of transcription factors, involved in skeletal muscle development. In this study we report the cDNA sequence and isolate the 5' upstream region of the mef2c gene from porcine genomic DNA using PCR-based GenomeWalker. The open reading frame of porcin...

journal_title：Molecular biology reports

authors： Liu M,Xu DQ,Peng J,Zheng R,Li F,Jiang SW

更新日期：2011-10-01 00:00:00

abstract：:Methyltransferases play essential roles in modulating important cellular and metabolic processes. A mouse putative N6-DNA methyltransferase gene (GenBank No AY456393) is a novel gene named mN6amt1(mN6A1). To investigate its function in cell fate and protein translation, RNA interference (RNAi)-mediated knock-down meth...

journal_title：Molecular biology reports

authors： Liu Y,Nie D,Huang Y,Lu G

更新日期：2009-04-01 00:00:00

abstract：:Staudtia kamerunensis (Myristicaceae) or 'Niové' is an evergreen tree widespread in Central African moist forests. The bark and seeds are used in traditional medicine, yet the tree is mainly harvested for its high quality, multi-purpose timber. To facilitate sustainable harvesting and conservation of the species, we a...

journal_title：Molecular biology reports

authors： Vanden Abeele S,Hardy OJ,Janssens SB

更新日期：2018-10-01 00:00:00

abstract：:Beta(2)-microglobulin (beta(2)m), a protein necessary for proper folding, peptide binding, and surface display of class I antigens plays an important role in immune response. The full-length cDNA containing beta(2)m was cloned from the spleen cDNA library of large yellow croaker Pseudosciaena crocea (Pscr-beta ( 2 ) m...

journal_title：Molecular biology reports

authors： Yu S,Chen X,Ao J

更新日期：2009-09-01 00:00:00

abstract：:Accurate normalization of gene expression with qRT-PCR depends on the use of appropriate reference genes (RGs) for the species under a given set of experimental conditions. Multiple RGs for gene expression analysis of soybean exposed to heavy metal stress treatment have not been reported in the literature. In this stu...

journal_title：Molecular biology reports

authors： Wang Y,Yu K,Poysa V,Shi C,Zhou Y

更新日期：2012-02-01 00:00:00

abstract：:Phage display procedure was applied to the N-terminal domain of human topoisomerase I. The consensus sequence identified for clones binding to the N-terminal domain was found in 35 human proteins that are either permanently or temporarily located in the nucleus. They are in majority involved in the DNA repair, transcr...

journal_title：Molecular biology reports

authors： Trzcińska AM,Girstun A,Piekiełko A,Kowalska-Loth B,Staroń K

更新日期：2002-12-01 00:00:00

abstract：:Chemerin, as a new member of adipokines family, is highly expressed in adipose tissue in rodent and its expression increases with obesity. Moreover, chemerin has been reported to have significant relationship with metabolic syndrome and insulin sensitivity. Here, the gene encoding chemerin from Xiang pig was cloned. T...

journal_title：Molecular biology reports

authors： Yang H,Li F,Kong X,Yuan X,Lian G,Geng M,Li T,Yin J,Yin Y

更新日期：2012-02-01 00:00:00

abstract：:Sperm-mediated gene transfer (SMGT) has been long heralded as a faster and cheaper alternative to more commonly used methods of producing transgenic animals. In this study, the capra semen ejaculates were pooled together and then incubated in vitro with DIG-labeled DNA. The binding and internalizing rates were observe...

journal_title：Molecular biology reports

authors： Zhao Y,Yu M,Wang L,Li Y,Fan J,Yang Q,Jin Y

更新日期：2012-03-01 00:00:00

abstract：:Fusarium head blight (FHB), predominantly caused by Fusarium graminearum, is a destructive disease that poses a serious threat to wheat (Triticum aestivum L.) production around the world. A suppression subtractive hybridization (SSH) cDNA library was constructed from F. graminearum infected spikes of a resistant Belgi...

journal_title：Molecular biology reports

authors： Muhovski Y,Batoko H,Jacquemin JM

更新日期：2012-10-01 00:00:00

abstract：:A pattern recognition protein (PRP), lipopolysaccharide and beta-1,3-glucan binding protein (LGBP) cDNA was cloned from the haemocyte of Chinese shrimp Fenneropenaeus chinensis by the techniques of homology cloning and RACE. Analysis of nucleotide sequence revealed that the full-length cDNA of 1,275 bp has an open rea...

journal_title：Molecular biology reports

authors： Liu F,Li F,Dong B,Wang X,Xiang J

更新日期：2009-03-01 00:00:00

abstract：:Salvia lachnostachys is an herbaceous plant with anti-inflammatory, analgesic and cytotoxic properties. This study investigated the antitumor effect of an ethanolic extract of Salvia lachnostachys leaves (EES) in a solid Ehrlich carcinoma model. Ehrlich cells were inoculated subcutaneously in the right pelvic member (...

journal_title：Molecular biology reports

authors： Corso CR,Stipp MC,Adami ER,da Silva LM,Mariott M,de Andrade SF,de Souza Ramos EA,Klassen G,Beltrame OC,Queiroz-Telles JE,de Oliveira CS,Stefanello MÉA,Acco A

更新日期：2019-10-01 00:00:00

abstract：:Caspases have been demonstrated to possess important functions in apoptosis and immune system in vertebrate. But there is less information reported on the oyster larval development. In the present work, two full-length molluscan caspase genes, named Cacaspase-2 and Cacaspase-3, were characterized for the first time fr...

journal_title：Molecular biology reports

authors： Yang B,Li L,Pu F,You W,Huang H,Ke C

更新日期：2015-05-01 00:00:00

abstract：:Substantial epidemiological studies have shown an association of obesity with the common gynecological malignancy, endometrial cancer. The relevant interactions and contribution of estradiol and the adipose cytokine, leptin, in endometrial lesions are not completely understood. Suitable animal models to understand the...

journal_title：Molecular biology reports

authors： Shetty A,Venkatesh T,Tsutsumi R,Suresh PS

更新日期：2020-01-01 00:00:00

abstract：:Fluorescent quantum dots (QDs) have been widely applied in biological and biomedical areas, but relatively little is known about the interaction of QDs with some natural enzymes. Herein, the interactions between 3-mercaptopropionic acid-capped CdTe QDs (MPA-QDs) and papain were systematically investigated by UV-Vis ab...

journal_title：Molecular biology reports

authors： Xiao Q,Qiu H,Huang S,Huang C,Su W,Hu B,Liu Y

更新日期：2013-10-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERP...

journal_title：Molecular biology reports

authors： An L,Yang T,Zhang Y,Lin Y,Zhang H,Jiao X,Hua L,Dai H,Wang C

更新日期：2012-02-01 00:00:00

abstract：:According to the stem cell theory for cancer, hepatocellular carcinomas are sustained by a group of cancer stem cells (CSCs) which are responsible for resistance to chemotherapy. In the present study we aimed to examine lipid metabolism in cancer stem cells induced by long-term treatment with sorafenib and its relatio...

journal_title：Molecular biology reports

authors： Bort A,Sánchez BG,de Miguel I,Mateos-Gómez PA,Diaz-Laviada I

更新日期：2020-04-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:The association between vitamin D receptor (VDR) gene polymorphisms and risk of benign prostatic hyperplasia (BPH) has been investigated in numerous publications, but published results remain inconclusive. Hence, we conducted this meta-analysis to derive a more precise conclusion. Four polymorphisms (Taq-I, Bsm-I, Apa...

journal_title：Molecular biology reports

authors： Zeng XT,Yao QS,Weng H,Li S,Huang JY,Wang XH

更新日期：2014-10-01 00:00:00