Meta-analysis of vitamin D receptor gene polymorphisms and benign prostatic hyperplasia risk.

abstract：:TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin processing recently, enzymes encoded by PCSK1 and PCSK2 are reported to play an important role in the process of proinsulin conversion. To investigate whether the single nucleotide polymorphisms...

journal_title：Molecular biology reports

authors： Zheng X,Ren W,Zhang S,Liu J,Li S,Li J,Yang P,He J,Su S,Li P

更新日期：2012-01-01 00:00:00

abstract：:The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...

journal_title：Molecular biology reports

authors： Zhang XM,Jing YP,Jia MY,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:Interferon gamma (IFN-γ) is an important immunoregulatory cytokine that has a central role against viral and bacterial infections. In this study, the cDNA encoding 141 amino acids of mature IFN-γ from mice splenocytes was cloned in a prokaryotic expression vector pQE 30. Optimization of expression conditions resulted ...

journal_title：Molecular biology reports

authors： Kumar M,Singh M,Singh SB

更新日期：2014-10-01 00:00:00

abstract：:Mitochondrial disorders are a frequent cause of neurological disability affecting children and adults. Traditionally, molecular diagnosis of mitochondrial diseases was mostly accomplished by the use of Sanger sequencing and PCR-RFLP. However, there are particular drawbacks associated with the use of these methods. Rec...

journal_title：Molecular biology reports

authors： Kauffman MA,Gonzlez-Morón D,Consalvo D,Westergaard G,Vazquez M,Mancini E,Taratuto AL,Rey R,Kochen S

更新日期：2012-06-01 00:00:00

abstract：:Infection with mycobacterium tuberculosis (MTB) can cause different outcomes in hosts with variant genetic backgrounds. Previously, we identified an intracellular pathogen resistance 1 (Ipr1) gene with the role of resistance of MTB infection in mice model. However, until now, its binding proteins have been little know...

journal_title：Molecular biology reports

authors： Cai L,Pan H,Trzciński K,Thompson CM,Wu Q,Kramnik I

更新日期：2010-12-01 00:00:00

abstract：:The interaction between ovalbumin (OVA) and three purine alkaloids (caffeine, theophylline and diprophylline) was investigated by the aid of intrinsic and synchronous fluorescence, ultraviolet-vis absorbance, resonance light-scattering spectra and three-dimensional fluorescence spectra techniques. Results showed that ...

journal_title：Molecular biology reports

authors： Wang RQ,Yin YJ,Li H,Wang Y,Pu JJ,Wang R,Dou HJ,Song CJ,Wang RY

更新日期：2013-04-01 00:00:00

abstract：:Molecular abnormalities in the 11p15.5 imprinted gene cluster lead to two different growth diseases: Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS). They are mainly caused by epigenetic alterations in one of the two imprinting 11p15 control regions (ICR1 and ICR2). These CpG-rich regions are diffe...

journal_title：Molecular biology reports

authors： Lukova M,Todorova A,Todorov T,Mitev V

更新日期：2013-01-01 00:00:00

abstract：:We report here cloning and characterization of a novel human gene, termed VMP, which is a vesicular membrane protein. RT-PCR analysis shows that VMP is expressed exclusively in brain of the 16 tissues examined, suggesting that it is a neuron-specific membrane protein. The cDNA encodes 195 amino acid with a putative mo...

journal_title：Molecular biology reports

authors： Cheng C,Xu J,Ye X,Dai J,Wu Q,Zeng L,Wang L,Zhao W,Ji C,Gu S,Xie Y,Mao Y

更新日期：2002-09-01 00:00:00

abstract：:Two DREB-like genes, designated as DmDREBa and DmDREBb, were isolated from chrysanthemum by RACE approach. The DmDREBa and DmDREBb genes encoded proteins of 191 and 185 amino acid residues with the predicted molecular mass of 21.66 and 20.99 kDa, respectively. Both DmDREBs proteins comprised a typical EREBP/AP2 domain...

journal_title：Molecular biology reports

authors： Yang Y,Wu J,Zhu K,Liu L,Chen F,Yu D

更新日期：2009-01-01 00:00:00

abstract：:An important alternative source of fish oil is its production by plants through metabolic engineering. To produce eicosapentaenoic acid (EPA, 20:5n-3) in peanut through the alternative Δ8-pathway, a plant expression vector containing five heterologous genes driven by the constitutive 35S promoter respectively, namely,...

journal_title：Molecular biology reports

authors： Wang C,Qing X,Yu M,Sun Q,Liu F,Qi B,Li X

更新日期：2019-02-01 00:00:00

abstract：:We performed PCR of many DNA fragments of 6-32 nucleotides in length. Some of the fragments expanded into kilobase lengths even in the absence of the complementary strand. The dramatic expansion was observed for (CA)8, (TG)8, (CA)4, (CA)6, (CA)12, (TG)4, (TG)6, (TG)12, (TC)10, (GA)10 and other single strands. Similar ...

journal_title：Molecular biology reports

authors： Reichová N,Kypr J

更新日期：2003-09-01 00:00:00

abstract：:The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Previous study showed that most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskele...

journal_title：Molecular biology reports

authors： Xu J,Gu S,Wang S,Dai J,Ji C,Jin Y,Qian J,Wang L,Ye X,Xie Y,Mao Y

更新日期：2003-12-01 00:00:00

abstract：:Sperm-mediated gene transfer (SMGT) has been long heralded as a faster and cheaper alternative to more commonly used methods of producing transgenic animals. In this study, the capra semen ejaculates were pooled together and then incubated in vitro with DIG-labeled DNA. The binding and internalizing rates were observe...

journal_title：Molecular biology reports

authors： Zhao Y,Yu M,Wang L,Li Y,Fan J,Yang Q,Jin Y

更新日期：2012-03-01 00:00:00

abstract：:There is an increasing body of evidence that a brief exposure to anesthesia induces ischemic tolerance in rat brain (anesthetic preconditioning). However, it is unknown whether preconditioning with sevoflurane, a commonly used volatile anesthetic in current clinical practice, produces a delayed window of neuroprotecti...

journal_title：Molecular biology reports

authors： Ye Z,Huang YM,Wang E,Zuo ZY,Guo QL

更新日期：2012-05-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) could infect porcine alveolar macrophages (PAM), and the CD169 and CD163 are identified as critical receptors on the surface of PAM, but whether the single nucleotide polymorphisms (SNPs) of these genes could influence the infection is remain unclear. In this...

journal_title：Molecular biology reports

authors： Ren YW,Zhang YY,Affara NA,Sargent CA,Yang LG,Zhao JL,Fang LR,Wu JJ,Fang R,Tong Q,Xiao J,Li JL,Jiang YB,Chen HC,Zhang SJ

更新日期：2012-11-01 00:00:00

abstract：:The blue swimming crab (Portunus pelagicus) is a valuable marine fishery resource in Indo-West Pacific Ocean. So far, rare genetic resource of this species is available. In this report, the restriction-site associated DNA (RAD) approach was employed to mine the genomic information and identify molecular markers in P. ...

journal_title：Molecular biology reports

authors： Wu Q,Miao G,Li X,Liu W,Ikhwanuddin M,Ma H

更新日期：2018-12-01 00:00:00

abstract：:Ventricular assist devices may function as a bridge to recovery or heart transplantation, however, little is known about its mechanisms. This study examined the role of matrix metalloproteinases (MMP)-tissue inhibitors of metalloproteinases (TIMP) axis in the process of recovery after unloading in a rat ischemic-induc...

journal_title：Molecular biology reports

authors： Wang WJ,Meng ZL,Mo YC,Liu JW,Sun CC,Hu SS,Zhang H

更新日期：2012-01-01 00:00:00

abstract：:The programmed cell death (PCD) is important in maintaining the cell number homoeostasis of tissues and organs in metazoan. This process is regulated by the inhibitors of apoptosis proteins (IAPs). The function and mechanism of IAPs have been well studied in animal embryonic development and human cancers. However, the...

journal_title：Molecular biology reports

authors： He HJ,Hou L,Wang JX,Zhao XF

更新日期：2012-02-01 00:00:00

abstract：:The relationship between genetic polymorphisms of glutathione S-transferase (GST) and the development of glioma has been investigated in several epidemiologic studies. However these studies report inconsistent results. In order to quantitatively summarise the evidence for such a relationship, a meta-analysis is conduc...

journal_title：Molecular biology reports

authors： Fan Z,Wu Y,Shen J,Zhan R

更新日期：2013-02-01 00:00:00

abstract：:Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an ex...

journal_title：Molecular biology reports

authors： Gismondi A,Nanni V,Monteleone V,Colao C,Di Marco G,Canini A

更新日期：2021-01-01 00:00:00

abstract：:Cellular cholesterol homeostasis is controlled by the sterol-regulatory element binding transcription factors (SREBFs) that are activated by an SREBF cleavage-activating protein (SCAP). SREBF-2 1784G > C single nucleotide polymorphism (SNP, rs2228314) and SCAP 2386A > G variant (rs12487736) are associated with early o...

journal_title：Molecular biology reports

authors： Chen Z,Ding Z,Ma G,Liu N,Qian Q

更新日期：2011-06-01 00:00:00

abstract：:Ethylene responsive factor (ERF) proteins play important roles in plant growth and development and regulate biotic and abiotic stress responses. In this study, a full length mRNA encoding a novel ERF-type transcription factor namely Ceratoides arborescens ERF protein (CeERF) was isolated from C. arborescens. The deduc...

journal_title：Molecular biology reports

authors： Dong J,Wang X,Wang K,Wang Z,Gao H

更新日期：2012-02-01 00:00:00

abstract：:One of the major limitations when attempting to obtain detailed biochemical, biophysical and immunological characterization of plant DNA mismatch repair proteins is their extremely low abundance in vivo under normal growth conditions. An initial analysis of PMS1 transcript level in various Arabidopsis thaliana tissues...

journal_title：Molecular biology reports

authors： Galles C,Gomez RL,Spampinato CP

更新日期：2011-02-01 00:00:00

abstract：:As initial steps to define how the 26S proteasome degrades ubiquitinated proteins in plants, we have characterized many of the subunits that comprise the proteolytic complex from Arabidopsis thaliana. A set of 23 Arabidopsis genes encoding the full complement of core particle (CP) subunits and a collection encoding 12...

journal_title：Molecular biology reports

authors： Fu H,Girod PA,Doelling JH,van Nocker S,Hochstrasser M,Finley D,Vierstra RD

更新日期：1999-04-01 00:00:00

abstract：:Various investigations have been so far performed for extraction of genomic DNA from plant tissues, in which the extracted intact DNA can be exploited for a diverse range of biological studies. Extraction of high quality DNA from leathery plant tissues (e.g., coniferous organs) appears to be a critical stage. Moreover...

journal_title：Molecular biology reports

authors： Barzegari A,Vahed SZ,Atashpaz S,Khani S,Omidi Y

更新日期：2010-02-01 00:00:00

abstract：:Amerindians immigrated to Madrid (Spain) region are about 10% of the present day population. Amerindians are believed to be the first American inhabitants, before Na-Dene speakers, Aleuts and Eskimo. They may initially have arrived to America from Siberia and also from other parts of Pacific Sea (South Asia, Polynesia...

journal_title：Molecular biology reports

authors： Parga-Lozano C,Rey-Medrano D,Gomez-Prieto P,Areces C,Moscoso J,Abd-El-Fatah-Khalil S,Moreno E,Arnaiz-Villena A

更新日期：2011-04-01 00:00:00

abstract：:Metabolic syndrome is an agglomeration of disorders including obesity, diabetes and cardiovascular diseases and characterized as chronic mild inflammation which elevates the circulatory inflammatory markers. This could be due to mitochondrial dysfunction, oxidative stress and hypoxia as a consequence of high fat diet ...

journal_title：Molecular biology reports

authors： Jha D,Mitra Mazumder P

更新日期：2019-04-01 00:00:00

abstract：:1-aminocyclopropane-1-carboxylic acid oxidase (ACO) enzyme is a member of the Fe II-dependent family of oxidases/oxygenases which require Fe(2+) as a cofactor, ascorbate as a cosubstrate and CO(2) as an activator. This enzyme catalyses the terminal step in the plant signaling of ethylene biosynthetic pathway. A 948 bp...

journal_title：Molecular biology reports

authors： Jafari Z,Haddad R,Hosseini R,Garoosi G

更新日期：2013-02-01 00:00:00

abstract：:Hepatitis B virus X protein (HBx) is closely involved in the development of hepatocellular carcinoma (HCC). Tumor suppressor p53 was reported to induce HBx degradation and repress its oncogenic function recently, but the molecular mechanism is unknown. In this study, we attempted to identify the underlying mechanism. ...

journal_title：Molecular biology reports

authors： Xian L,Zhao J,Wang J,Fang Z,Peng B,Wang W,Ji X,Yu L

更新日期：2010-07-01 00:00:00

abstract：:The lysyl oxidase-like 2 (LOXL2) protein is a human paralogue of lysyl oxidase (LOX) that functions as an amine oxidase for formation of lysine-derived cross-links found in collagen and elastin. In addition to the C-terminal domains characteristic to the LOX family members, LOXL2 contains four scavenger receptor cyste...

journal_title：Molecular biology reports

authors： Kim YM,Kim EC,Kim Y

更新日期：2011-01-01 00:00:00