Cloning, expression and characterization of a novel human VMP gene.

abstract：:Apolipoprotein AV (apoAV) modulates plasma triglyceride levels, which is an independent risk factor for cardiovascular disease. ApoAV is also involved in atherosclerosis lesion formation. In order to systematically evaluate the apolipoprotein-related gene profile in tree shrew, a model for its insusceptibility to athe...

journal_title：Molecular biology reports

authors： Li G,Luo H,Sun G,Wu G,Wu G,Wang Y,Man Y,Wang S,Li J,Chen B

更新日期：2013-09-01 00:00:00

abstract：:Transcriptional factors are the major regulators of plant signaling pathways in response to environmental stresses i.e., drought, salinity and cold. Hereby, the GhMYB108-like was characterized to determine whether it regulate these stresses. The GhMYB108-like cDNA consisted of 1107 base pairs (bp) with 807 open readin...

journal_title：Molecular biology reports

authors： Ullah A,Ul Qamar MT,Nisar M,Hazrat A,Rahim G,Khan AH,Hayat K,Ahmed S,Ali W,Khan A,Yang X

更新日期：2020-03-01 00:00:00

abstract：:LNX (Ligand of Numb-protein X) was originally isolated as a binding partner to the cell-fate Determinant Numb during development, and then identified to act as a RING finger-type E3 ubiquitin ligase for the ubiquitylation and degradation of Numb. LNX contains 4 PDZ domains which are proved to play a central role in or...

journal_title：Molecular biology reports

authors： Zheng D,Sun Y,Gu S,Ji C,Zhao W,Xie Y,Mao Y

更新日期：2010-06-01 00:00:00

abstract：:Sheep are valuable resources for the wool industry. Wool growth of Aohan fine wool sheep has cycled during different seasons in 1 year. Therefore, identifying genes that control wool growth cycling might lead to ways for improving the quality and yield of fine wool. In this study, we employed Agilent sheep gene expres...

journal_title：Molecular biology reports

authors： Liu N,Li H,Liu K,Yu J,Cheng M,De W,Liu J,Shi S,He Y,Zhao J

更新日期：2014-08-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-α) and interleukin 1 beta (IL-1β) genetic variants which resulting in TNF-α and IL-1 overproduction may increase susceptibility to autoimmune diseases such as atherosclerosis. We have studied the association of TNF-α G308A and IL-1β (+3953) C/T polymorphism with myocardial infarction i...

journal_title：Molecular biology reports

authors： Zeybek U,Toptas B,Karaali ZE,Kendir M,Cakmakoglu B

更新日期：2011-11-01 00:00:00

abstract：:We have cloned two full-length cDNAs from two ferritin genes (Aifer1 and Aifer2) of the bay scallop, Argopecten irradians (Lamarck 1819). The cDNAs are 1,019 and 827 bp in length and encode proteins of 171 and 173 amino acids, respectively. The 5' UTR of each contains a conserved iron response element (IRE) motif. Seq...

journal_title：Molecular biology reports

authors： He X,Zhang Y,Wu X,Xiao S,Yu Z

更新日期：2011-03-01 00:00:00

abstract：:BURP domain-containing genes comprise a large plant-specific family, yet the functions are very poorly understood, especially in maize (Zea mays) and sorghum (Sorghum vulgare). In this study, 26 BURP family genes in maize (ZmBURP01-15) and sorghum (SbBURP01-11) were identified including the gene structure, phylogeneti...

journal_title：Molecular biology reports

authors： Gan D,Jiang H,Zhang J,Zhao Y,Zhu S,Cheng B

更新日期：2011-10-01 00:00:00

abstract：:Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor sup...

journal_title：Molecular biology reports

authors： de Lourdes Perim A,Guembarovski RL,Oda JM,Lopes LF,Ariza CB,Amarante MK,Fungaro MH,de Oliveira KB,Watanabe MA

更新日期：2013-07-01 00:00:00

abstract：:The response of glycolysis to exposure of glucose in non-growing S. cerevisiae cells from diauxic shift was monitored. The result was compared to a kinetic model of glycolysis with branches to glycogen, trehalose, glycerol, and succinate. Experimental data at steady-state concentrations of metabolites in the upper par...

journal_title：Molecular biology reports

authors： Albers E,Bakker BM,Gustafsson L

更新日期：2002-01-01 00:00:00

abstract：:Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indic...

journal_title：Molecular biology reports

authors： Hayashida K,Kohno S

更新日期：2009-07-01 00:00:00

abstract：:Methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism shows considerable heterogeneity in its distribution in humans worldwide. The current study was conducted to investigate whether this polymorphism exhibited adaptive developmental plasticity in the control of the TT-genotype frequency. We screened 1,818 S...

journal_title：Molecular biology reports

authors： Naushad SM,Krishnaprasad C,Devi AR

更新日期：2014-05-01 00:00:00

abstract：:Identifying patients at high risk of metastasis is a major challenge in lung adenocarcinoma (ADC) therapy, therefore discovery of noninvasive biomarkers and therapeutic targets is urgent. We found significant differences between the secretomes of differentially expressed proteins in lung ADC cell lines, clinical tissu...

journal_title：Molecular biology reports

authors： Liu Z,Gao Y,Hao F,Lou X,Zhang X,Li Y,Wu D,Xiao T,Yang L,Li Q,Qiu X,Wang E

更新日期：2014-11-01 00:00:00

abstract：:The lipoprotein lipase (LPL) gene can be considered a functional candidate gene that regulates fatty acid composition. In this study, genetic associations between fatty acid composition and exonic single nucleotide polymorphisms (SNPs) in the LPL gene were examined using 612 Korean cattle. We investigated the relation...

journal_title：Molecular biology reports

authors： Oh D,La B,Lee Y,Byun Y,Lee J,Yeo G,Yeo J

更新日期：2013-04-01 00:00:00

abstract：:Sulfonamide derivatives, such as sulfadiazine (SD) are used as antibiotics and, very recently, anti-amyloid properties of these have been reported. We have evaluated binding of SD with bovine serum albumin (BSA) followed by unfolding of protein. Studies were accomplished at physiological conditions of temperature (37 ...

journal_title：Molecular biology reports

authors： Al-Lohedan HA,Sajih Ali M

更新日期：2013-11-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the main cause of blindness among the people in productive age. The purpose of this literature review is to highlight recent achievements in the genetics of diabetic retinopathy with particular focus on candidate gene studies. We...

journal_title：Molecular biology reports

authors： Priščáková P,Minárik G,Repiská V

更新日期：2016-12-01 00:00:00

abstract：:Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...

journal_title：Molecular biology reports

authors： Vasconcelos GM,Gonçalves BA,Montalvão-de-Azevedo R,Thuler LC,Braga FH,Pombo-de-Oliveira MS,de Camargo B,Brazilian Embryonal Tumor Group.

更新日期：2014-09-01 00:00:00

abstract：:In clinical practice, most patients with non small cell lung cancer (NSCLC) who respond to tyrosine kinase inhibitors eventually progress because of an acquired resistance mutation, T790M, in epidermal growth factor receptor (EGFR). Thus, it is important to identify a new drug to reduce resistance. The aim of this stu...

journal_title：Molecular biology reports

authors： Zhu H,Cheng H,Ren Y,Liu ZG,Zhang YF,De Luo B

更新日期：2012-04-01 00:00:00

abstract：:Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there is no study investigating the role of the genes in paranasal sinus carcinomas. The aim of the study was to assess the role of the PI3K/AKT/mTOR ...

journal_title：Molecular biology reports

authors： Biray Avci C,Sezgin B,Goker Bagca B,Karci HB,Gode S

更新日期：2020-05-01 00:00:00

abstract：:The cell cycle is a complex and strictly controlled process, consisting of different phases. Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the dereg...

journal_title：Molecular biology reports

authors： Caglar HO,Biray Avci C

更新日期：2020-04-01 00:00:00

abstract：:Steroid administration, which is commonly performed for the treatment of autoimmune inflammatory diseases, cancers or organ transplantation, has been a leading cause of nontraumatic osteonecrosis of the femoral head (ONFH). Single nucleotide polymorphisms (SNPs) of the adenosine triphosphate-binding cassette B1 (ABCB1...

journal_title：Molecular biology reports

authors： Zhang Y,Kong X,Wang R,Li S,Niu Y,Zhu L,Chen W,Lin N

更新日期：2014-05-01 00:00:00

abstract：:It is well known that transcriptionally inactive rRNA genes are correlated with DNA hyper-methylation and histone hypo-methylation and there is clear evidence in humans that DNA and histone modification which alter chromatin structure are related to chromosome fragility. Very little is known about the biological cause...

journal_title：Molecular biology reports

authors： Singh M,Barman AS

更新日期：2013-01-01 00:00:00

abstract：:Current surgical reconstruction for soft tissue replacement involves lipotransfer to restore soft tissue replacements but is limited by survival and longevity of the fat tissue. Alternative approaches to overcome these limitations include using biodegradable scaffolds with stem cells with growth factors to generate so...

journal_title：Molecular biology reports

authors： Naderi N,Griffin MF,Mosahebi A,Butler PE,Seifalian AM

更新日期：2020-03-01 00:00:00

abstract：:Responses of plants to salinity stress and the development of salt tolerance are extremely complex. Proteomics is a powerful technique to identify proteins associated with a particular environmental or developmental signal. We employed a proteomic approach to further understand the mechanism of plant responses to sali...

journal_title：Molecular biology reports

authors： Fatehi F,Hosseinzadeh A,Alizadeh H,Brimavandi T,Struik PC

更新日期：2012-05-01 00:00:00

abstract：:Infection with mycobacterium tuberculosis (MTB) can cause different outcomes in hosts with variant genetic backgrounds. Previously, we identified an intracellular pathogen resistance 1 (Ipr1) gene with the role of resistance of MTB infection in mice model. However, until now, its binding proteins have been little know...

journal_title：Molecular biology reports

authors： Cai L,Pan H,Trzciński K,Thompson CM,Wu Q,Kramnik I

更新日期：2010-12-01 00:00:00

abstract：:Syndecan-1 has been implicated in tumorigenesis and progression of various human malignancies. Recent studies have demonstrated that syndecan-1 may have a different function and biological activity depending on the specific tumor type. Therefore, the aim of this study was to investigate the clinical significance of sy...

journal_title：Molecular biology reports

authors： Xu Y,Yuan J,Zhang Z,Lin L,Xu S

更新日期：2012-09-01 00:00:00

abstract：:Due to being stable in the circulatory system plasma miRNAs have been detected in various diseases including coronary artery disease (CAD) which is the major cause of mortality and morbidity worldwide. Atherosclerosis is the major cause of CAD. The first and most important event in the progression of atherosclerosis i...

journal_title：Molecular biology reports

authors： Gorur A,Celik A,Yildirim DD,Gundes A,Tamer L

更新日期：2019-02-01 00:00:00

abstract：:F-box proteins play important roles in the regulation of various developmental processes in plants. Approximately 1796 F-box genes have been identified in the wheat genome, but details of their functions remain unknown. Moreover, not much was known about the roles of kelch repeat domain-containing F-box genes (TaKFBs)...

journal_title：Molecular biology reports

authors： Hong MJ,Kim DY,Choi HI,Seo YW,Kim JB

更新日期：2020-02-01 00:00:00

abstract：:Members of the methyl binding domain (MBD) protein family are known for binding to methylated DNA by recognizing methylated cytosines. Their original function is to regulate protein biosynthesis by recruitment of transcriptional repression complexes to silence gene expression. The aim of the presented work was to dete...

journal_title：Molecular biology reports

authors： Födermayr M,Pröll J,Zach O,Wechselberger C,Lutz D

更新日期：2009-09-01 00:00:00

abstract：:In the present study, we characterized an evolutionarily conserved non-transmembrane ATP-binding cassette protein: hABCF3. Subcellular immunofluorescence staining demonstrated that hABCF3 localizes preferentially in cytoplasm, unlike its paralog protein hABCF1, which localizes in both cytoplasm and nucleus. Quantitati...

journal_title：Molecular biology reports

authors： Zhou J,Lin Y,Shi H,Huo K,Li Y

更新日期：2013-10-01 00:00:00

abstract：:Published data on the association of vascular endothelial growth factor (VEGF) -1154G>A polymorphism with cancer risk is inconclusive. To derive a more precise estimation of association between VEGF -1154G>A polymorphism and the risk of cancer, we performed a meta-analysis of 7,071 cancer cases and 7,693 controls from...

journal_title：Molecular biology reports

authors： Hong TT,Zhang RX,Wu XH,Hua D

更新日期：2012-05-01 00:00:00