Candidate gene studies of diabetic retinopathy in human.

abstract：:The interaction between benzophenone (BP) and bovine serum albumin (BSA) was investigated by the methods of fluorescence spectroscopy combined with UV-Vis absorption and circular dichroism (CD) measurements under simulative physiological conditions. The experiment results showed that the fluorescence quenching of BSA ...

journal_title：Molecular biology reports

authors： Zhang YZ,Zhang J,Li FF,Xiang X,Ren AQ,Liu Y

更新日期：2011-04-01 00:00:00

abstract：:Many studies have examined the association between the GSTP1 Ile105Val (rs 1695) gene polymorphism and lung cancer risk in various populations, but their results have been inconsistent. To assess this relationship more precisely, a meta-analysis was performed. The PubMed and CNKI database was searched for case-control...

journal_title：Molecular biology reports

authors： Xu CH,Wang Q,Zhan P,Qian Q,Yu LK

更新日期：2014-07-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:The plasticity of the central nervous system helps form the basis for the neurobiology of learning and memory. Long-term potentiation (LTP) is the main form of synaptic plasticity, reflecting the activity level of the synaptic information storage process, and provides a good model to study the underlying mechanisms of...

journal_title：Molecular biology reports

authors： Peng S,Zhang Y,Zhang J,Wang H,Ren B

更新日期：2011-01-01 00:00:00

abstract：:α-Synuclein is a presynaptic neuronal protein that is abundant in the human brain and is linked genetically and neuropathologically to Parkinson's disease (PD). The E46K mutation of the α-synuclein gene has been linked to autosomal dominant early-onset of PD. Crocin is a carotenoid chemical compound of saffron that ha...

journal_title：Molecular biology reports

authors： Ghasemi Tigan M,Ghahghaei A,Lagzian M

更新日期：2019-08-01 00:00:00

abstract：:Covalent modification/demodification cycles are common in metabolism. When the modification and demodification steps are carried out by two independent enzymes, the degree of modification can be ultrasensitive to the total concentration of either catalyst. We recently showed that the degree of modification of a target...

journal_title：Molecular biology reports

authors： Ortega F,Ehrenberg M,Acerenza L,Westerhoff HV,Mas F,Cascante M

更新日期：2002-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease in which numerous cells and mediators affect inflammatory conditions and disease severity. To compare the serum levels of adiponectin, vitamin D, copper, and zinc in patients with RA and to investigate the relationship between these parameters and RA severity...

journal_title：Molecular biology reports

authors： Khajoei S,Hassaninevisi M,Kianmehr N,Seif F,Khoshmirsafa M,Shekarabi M,Samei A,Haghighi A

更新日期：2019-04-01 00:00:00

abstract：:Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium lat...

journal_title：Molecular biology reports

authors： Sinha VB,Grover A,Singh S,Pande V,Ahmed Z

更新日期：2014-09-01 00:00:00

abstract：:Many studies have been performed to identify regulatory circuit underlying plant stress tolerance. However, the reliability of some findings has been criticized because of exclusive use of stress sensitive plant species such as Arabidopsis thaliana. Sensitive plant species often harbor narrow defensive mechanisms and ...

journal_title：Molecular biology reports

authors： Shamloo-Dashtpagerdi R,Razi H,Ebrahimie E,Niazi A

更新日期：2018-10-01 00:00:00

abstract：:Overexpression of ATP-binding cassette (ABC) transporters causing multidrug resistance (MDR) in cancer cells is one of the major obstacles in cancer chemotherapy. The 5-FU resistant subclone (HL-60/5FU) of the human HL-60 promyelocytic leukemia cell line was selected by the conventional method of continuous exposure o...

journal_title：Molecular biology reports

authors： Długosz-Pokorska A,Pięta M,Janecki T,Janecka A

更新日期：2019-12-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:Current study was conducted to investigation of effect of magnetic field on cell dedifferentiation and follow it callus induction derived from mature embryo culture in bread wheat genotypes. For this purpose, a factorial experiment based on completely randomized design was carried out with two wheat genotypes and thre...

journal_title：Molecular biology reports

authors： Kahrizi D,Cheghamirza K,Akbari L,Rostami-Ahmadvandi H

更新日期：2013-02-01 00:00:00

abstract：:It has been suggested that the estrogen receptor alpha (ERα) and vitamin D receptor (VDR) genes as possibly implicated in reduced bone mineral density (BMD) in osteoporosis. The present study investigated the relation of ERα PvuII/XbaI polymorphisms and VDR FokI/TaqI polymorphisms with BMD in Turkish postmenopausal wo...

journal_title：Molecular biology reports

authors： Kurt O,Yilmaz-Aydogan H,Uyar M,Isbir T,Seyhan MF,Can A

更新日期：2012-06-01 00:00:00

abstract：:Methicillin resistant Staphylococcus aureus (MRSA) is one of the challenging bacterial pathogen due to its acquired resistance to the β lactam antibiotics. The Sortase A is an enzyme of Gram-positive bacteria including S. aureus to anchor surface proteins to the cell wall. Sortase A is well studied enzyme and consider...

journal_title：Molecular biology reports

authors： Uddin R,Saeed K

更新日期：2014-08-01 00:00:00

abstract：:Folate is crucial for various cellular functions. Several transport mechanisms allow folate to enter the intracellular compartment with folate receptor-α being the major high-affinity receptor. Rare genetic variations in exons of the FR-α gene, FOLR1, were recently shown to cause severe folate deficiency accompanied b...

journal_title：Molecular biology reports

authors： Nilsson TK,Laanpere M,Altmäe S,Serra-Majem L,Salumets A

更新日期：2012-04-01 00:00:00

abstract：:Overexpression of differentiated embryo chondrocyte 1 (DEC1) has been reported to contribute to the cellular differentiation, proliferation, and apoptosis of various cancers. Our previous studies have shown that DEC1 was highly expressed in gastric cancer (GCa) tissues. However, there is no report about the expression...

journal_title：Molecular biology reports

authors： Zheng Y,Shi X,Wang M,Jia Y,Li B,Zhang Y,Liu Q,Wang Y

更新日期：2012-04-01 00:00:00

abstract：:Common bacterial blight (CBB), incited by Xanthomonas axonopodis pv. phaseoli (Xap), is a serious seed-borne disease of common bean (Phaseolus vulgaris L.) in both temperate and tropical production zones. The line HR45 is highly resistant to Xap infection on leaves and pods in both field and greenhouse. To understand ...

journal_title：Molecular biology reports

authors： Shi C,Chaudhary S,Yu K,Park SJ,Navabi A,McClean PE

更新日期：2011-01-01 00:00:00

abstract：:We have chosen to test the safety of human intracerebroventricular (ICV) brain injections of autologous non-genetically-modified adipose-derived stromal vascular fraction (ADSVF). In this IRB-approved trial, 24 patients received ICV ADSVF via an implanted reservoir between 5/22/14 and 5/22/17. Seven others were inject...

journal_title：Molecular biology reports

authors： Duma C,Kopyov O,Kopyov A,Berman M,Lander E,Elam M,Arata M,Weiland D,Cannell R,Caraway C,Berman S,Scord K,Stemler L,Chung K,Khoudari S,McRory R,Duma C,Farmer S,Bravo A,Yassa C,Sanathara A,Singh E,Rapaport B

更新日期：2019-10-01 00:00:00

abstract：:Acute and chronic viral hepatitis infections are corresponding to increase the risk of different types of hematological malignancies especially with leukemia. In this study the serological and molecular markers of hepatitis viruses were evaluated in patients with different types of leukemia in comparing with control g...

journal_title：Molecular biology reports

authors： Mirzaee M,Yaghobi R,Ramzi M,Roshan Nia M

更新日期：2012-02-01 00:00:00

abstract：:The recombinant catalytic subunit of human protein kinase CK2 bas been mutagenised at the C-terminal region in an attempt to induce this tail to fold. We suppose in fact that this unstructured C-terminus just might be responsible for the high degradability of the human enzyme. On the basis of theoretical calculations ...

journal_title：Molecular biology reports

authors： Grasselli E,Noviello G,Rando C,Nicolini C,Vergani L

更新日期：2003-06-01 00:00:00

abstract：:DNA polymerase alpha from germinated wheat embryos was purified by ammonium sulphate fractionation, chromatography on DEAE-Toyopearl, followed by phosphocellulose and heparin Sepharose columns. The specific activity of the purified enzyme was more than 60,000 units/mg. It belongs to the alpha-type according to the lar...

journal_title：Molecular biology reports

authors： Balmukhanov TS,Erekenov AM,Ajtkhozhina NA

更新日期：1992-02-01 00:00:00

abstract：:A method is described which demonstrates the posibility of visualizing protein-complexed DNA by using pronase for both deproteinization and spreading of DNA for electron microscopy. The results show that proteolytic digestion is complete even under conditions of short formaldehyde fixation and pronase is an excellent ...

journal_title：Molecular biology reports

authors： Tsaneva I,Tsanev R

更新日期：1979-08-31 00:00:00

abstract：:Genes for individual domains such as CH, lim, ankyrin, PH and RhoGAP, IQ motif, Ig_FLMN, spectrin, and EF hand probably existed in early evolution before there were plants, fungi or animals so that when we examine multidomain proteins in Arabidopsis, Saccharomyces, Dictyostelium or Homo Sapiens we encounter various co...

journal_title：Molecular biology reports

authors： Friedberg F

更新日期：2011-01-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:Nerve growth factor (NGF) is required for the differentiation and maintenance of sympathetic and sensory neurons. In the present study, the recombinant expression of human nerve growth factor beta (hNGF-β) gene in rabbit bone marrow mesenchymal stem cells (rMSCs) was undertaken. Recombinant vector containing hNGF-β wa...

journal_title：Molecular biology reports

authors： Fan BS,Lou JY

更新日期：2010-12-01 00:00:00

abstract：:Long term intake of high-glucose diet (HGD) may induce many diseases such as dyslipidemia, fatty liver and diabetes disease. Most of the research for molecular mechanisms of the association between HGD and the above diseases focus on the metabolism of glucose and lipid. However, there are few studies on molecular mech...

journal_title：Molecular biology reports

authors： Du D,Shi YH,Le GW

更新日期：2010-04-01 00:00:00

abstract：:To investigate the influence of NF-κB antisense oligonucleotide on transdifferentiation of fibroblast in the pathological process of bleomycin-induced pulmonary fibrosis in mice. 6 h before molding of C57BL/6 model of pulmonary fibrosis in mice, NF-κB antisense oligonucleotide was injected from caudal vein. Then the l...

journal_title：Molecular biology reports

authors： Zhou Y,Zhang X,Tan M,Zheng R,Zhao L

更新日期：2014-06-01 00:00:00

abstract：:BACs-on-Beads (BoBs™) assay is a rapid aneuploidy test (RAT) that detects numerical chromosomal aneuploidies and multiple microdeletion/microduplication syndromes. This study was conducted to appraise the usefulness of the BoB™ assay as a complementary diagnostic tool to conventional karyotyping for the rapid detectio...

journal_title：Molecular biology reports

authors： Farra C,Nassar AH,Mirza F,Abdouni L,Souaid M,Awwad J

更新日期：2020-01-01 00:00:00

abstract：:Fluorescent proteins related to and derived from green fluorescent protein (GFP) are widely used as tools for investigating a wide range of biological processes. In particular, GFP and its relatives have been used extensively as qualitative reporters of gene expression in many different organisms, but relatively few s...

journal_title：Molecular biology reports

authors： Lissemore JL,Bayes J,Calvey M,Reineke L,Colagiavanni A,Tscheiner M,Mascotti DP

更新日期：2009-05-01 00:00:00

abstract：:Recently, differentiated somatic cells had been reprogrammed to pluripotential state in vitro, and various tissue cells had been elicited from those cells. Epigenetic modifications allow differentiated cells to perpetuate the molecular memory needed for the cells to retain their identity. DNA methylation and histone d...

journal_title：Molecular biology reports

authors： Zhang XM,Li QM,Su DJ,Wang N,Shan ZY,Jin LH,Lei L

更新日期：2010-03-01 00:00:00