Sensitivity analysis of metabolic cascades catalyzed by bifunctional enzymes.

abstract：:This study is aimed to identify polymorphic microsatellite markers and establish their potential for population genetics studies in three carp (family cyprinidae; subfamily cyprininae) species, Labeo rohita, Catla catla and Cirrhinus mrigala through use of cyprinid primers. These species have high commercial value and...

journal_title：Molecular biology reports

authors： Masih P,Luhariya RK,Das R,Gupta A,Mohindra V,Singh RK,Srivastava R,Chauhan UK,Jena JK,Lal KK

更新日期：2014-08-01 00:00:00

abstract：:The spleen plays a crucial role in innate and adaptive immunity in bony fish. Consequently, this organ is well suited to assess the immune competence of an organism and hence provides useful information for comparison and classification of production traits of food fish, such as robustness and susceptibility. To gain ...

journal_title：Molecular biology reports

authors： Köbis JM,Rebl A,Kühn C,Goldammer T

更新日期：2013-02-01 00:00:00

abstract：:Transcriptome from high throughput sequencing-by-synthesis is a good resource of molecular markers. In this study, we present utility of massively parallel sequencing by synthesis for profiling the transcriptome of red pepper (Capsicum annuum L. TF68) using 454 GS-FLX pyrosequencing. Through the generation of approxim...

journal_title：Molecular biology reports

authors： Lu FH,Cho MC,Park YJ

更新日期：2012-03-01 00:00:00

abstract：:In the present work, Site-directed mutagenesis to insert the Glu50Lys amino acid substitution was achieved by PCR using plasmid pBluescript-OPTN. Mutated human OPTN(E50K) gene-driven mouse c-kit promoter was constructed and confirmed by endonuclease digestion and sequence analysis. Transgenic mice were generated via t...

journal_title：Molecular biology reports

authors： Meng Q,Xiao Z,Yuan H,Xue F,Zhu Y,Zhou X,Yang B,Sun J,Meng B,Sun X,Cheng F

更新日期：2012-02-01 00:00:00

abstract：:We report here cloning and characterization of a novel human gene, termed VMP, which is a vesicular membrane protein. RT-PCR analysis shows that VMP is expressed exclusively in brain of the 16 tissues examined, suggesting that it is a neuron-specific membrane protein. The cDNA encodes 195 amino acid with a putative mo...

journal_title：Molecular biology reports

authors： Cheng C,Xu J,Ye X,Dai J,Wu Q,Zeng L,Wang L,Zhao W,Ji C,Gu S,Xie Y,Mao Y

更新日期：2002-09-01 00:00:00

abstract：:STAT4 is a transcription factor that has been implicated in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Recently, several reports has documented that a STAT4 haplotype is associated with RA, SLE and Sjogren's syndrome. To summarize and review these findings, we conducted a met...

journal_title：Molecular biology reports

authors： Ji JD,Lee WJ,Kong KA,Woo JH,Choi SJ,Lee YH,Song GG

更新日期：2010-01-01 00:00:00

abstract：:This study was aimed to evaluate the regulation mechanism of cortactin (CTTN) on matrix metalloproteinases 9 (MMP-9) and its relations with Exo70 in invasion of hepatoma carcinoma (HCC) cells. The expression levels of CTTN, Exo70 and MMP-9 were detected in normal hepatocytes and various HCC cells by real-time PCR. The...

journal_title：Molecular biology reports

authors： Zhao G,Zhang H,Huang Z,Lv L,Yan F

更新日期：2016-05-01 00:00:00

abstract：:Ribonuclease P (RNase P) is a key enzyme involved in tRNA biosynthesis. It catalyses the endonucleolytic cleavage of nearly all tRNA precursors to produce 5'-end matured tRNA. RNase P activity has been found in all organisms examined, from bacteria to mammals. Eubacterial RNase RNA is the only known RNA enzyme which f...

journal_title：Molecular biology reports

authors： Drainas D

更新日期：1995-01-01 00:00:00

abstract：:The influence of peptidyl-tRNA on the dissociation of yeast 80 S ribosomes into subunits was studied. For this purpose temperature-sensitive (ts) suppressor strain of yeast Saccharomyces cervisiae carrying a defect in peptide chain termination was used. It was found that peptidyl-tRNA did not influence the dissociatio...

journal_title：Molecular biology reports

authors： Surguchov AP,Fominykch ES,Lyzlova LV

更新日期：1978-06-16 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：:Three members of Brassica napus TRANSPARENT TESTA 2 (BnTT2) gene family encoding potential R2R3-MYB regulatory proteins of proanthocyanidin biosynthesis were isolated. BnTT2-1, BnTT2-2, and BnTT2-3 are 1102 bp with two introns, and have a 938-bp full-length cDNA with a 260 amino acid open reading frame. They share 98....

journal_title：Molecular biology reports

authors： Wei YL,Li JN,Lu J,Tang ZL,Pu DC,Chai YR

更新日期：2007-06-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is an aggressive BC subtype characterized by HER2 overexpression/amplification. Genomic alterations of HER2 and others have been reported to be associated with, HER2 overexpression and prediction of trastuzumab-response. Here, we aimed at ide...

journal_title：Molecular biology reports

authors： Singla H,Kaur RP,Shafi G,Vashistha R,Banipal RPS,Kumar V,Munshi A

更新日期：2019-02-01 00:00:00

abstract：:Finger millet (Eleusine coracana L.) is an important crop used for food, forage, and industrial products. Three DNA marker techniques, random amplified polymorphic DNA (RAPD), simple sequence repeat (SSR) and cytochrome P(450) gene based markers were used for the detection of genetic polymorphism in 83 accessions of f...

journal_title：Molecular biology reports

authors： Panwar P,Saini RK,Sharma N,Yadav D,Kumar A

更新日期：2010-12-01 00:00:00

abstract：:F-box proteins are key components of the ubiquitin (Ub)/26S proteasome pathway that mediates selective degradation of regulatory proteins involved in a wide variety of cellular processes affecting eukaryotic cells. In plants, F-box genes form one of the largest multigene superfamilies and control many important biolog...

journal_title：Molecular biology reports

authors： Paquis S,Mazeyrat-Gourbeyre F,Fernandez O,Crouzet J,Clément C,Baillieul F,Dorey S

更新日期：2011-06-01 00:00:00

abstract：:Insulin-like growth factor (IGF) expression plays a critical role in the endocrine regulation of proliferation, differentiation, and growth in shellfish as well as in fish. The Pacific oyster, Crassostrea gigas, is a significant aquaculture species that comprises a large percentage of the Korean shellfish industry; mo...

journal_title：Molecular biology reports

authors： Moon JS,Choi YH

更新日期：2019-02-01 00:00:00

abstract：:Scytovirin is a lectin isolated from the cyanobacterium Scytonema varium that has shown activity against HIV, SARS coronavirus and Zaire Ebola virus. Its 95 amino acids are divided into two structural domains (SD), the first spanning amino acids 1-48 (SD1) and the second 49-95 (SD2). Interestingly, the domains are nea...

journal_title：Molecular biology reports

authors： Siqueira AS,Lima ARJ,de Souza RC,Santos AS,Vianez Júnior JLDSG,Gonçalves EC

更新日期：2017-08-01 00:00:00

abstract：:Serotonin receptor (5-HT) is a biogenic amine acting as a neurotransmitter and neuromodulator that mediates various aspects of reproduction and gametogenesis. The full-length nucleotide sequence of Haliotis discus hannai encodes a protein of 417 amino acids with a predicted molecular mass of 46.54 kDa and isoelectric ...

journal_title：Molecular biology reports

authors： Sharker MR,Sukhan ZP,Kim SC,Lee WK,Kho KH

更新日期：2020-01-01 00:00:00

abstract：:Several lines of evidence indicate that inflammatory processes play pivotal role in the development of intracranial aneurysm (IA). Recently, polymorphisms in the interleukin-12 (IL-12) gene were shown to be associated with immune-mediated inflammatory disease. The aim of this study was to investigate the interactions ...

journal_title：Molecular biology reports

authors： Li LJ,Pan XM,Sima X,Li ZH,Zhang LS,Sun H,Zhu Y,Liang WB,Gao LB,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:We investigated phenotypic variations for pod shattering, pod length and number of seeds per pod in large germplasm collections of Brassica juncea (2n = 36; AABB) and its progenitor species, B. rapa (2n = 20; AA) and B. nigra (2n = 16; BB). Pod shatter resistance was measured as energy required for rupturing a mature ...

journal_title：Molecular biology reports

authors： Kaur J,Akhatar J,Goyal A,Kaur N,Kaur S,Mittal M,Kumar N,Sharma H,Banga S,Banga SS

更新日期：2020-04-01 00:00:00

abstract：:It is well-established that an impaired adipose tissue function and morphology caused by a dysregulated gene expression contribute substantially to obesity. Nowadays, animal model studies and in vitro surveys provide evidence for possible roles of HDACs as emerging epigenetic players in the pathogenesis of obesity. Ho...

journal_title：Molecular biology reports

authors： Jannat Ali Pour N,Meshkani R,Toolabi K,Mohassel Azadi S,Zand S,Emamgholipour S

更新日期：2020-05-01 00:00:00

abstract：:Potato (Solanum tubersosum L.) is relatively vulnerable to abiotic stress conditions such as drought, but the tolerance mechanisms to such stress in potato are largely unknown. To gain insight into the transcriptome dynamics that are associated with drought stress, genome-wide gene expression profile was conducted by ...

journal_title：Molecular biology reports

authors： Zhang N,Liu B,Ma C,Zhang G,Chang J,Si H,Wang D

更新日期：2014-01-01 00:00:00

abstract：:The cytotoxic T lymphocyte-associated antigen 4 gene (CTLA4) has a crucial role in regulation of T cell proliferation and mediates T cell apoptosis by encoding the T cell receptor. Schizophrenia (SCZ) patients often have abnormalities in terms of the function and development of the immune system. The aim of the presen...

journal_title：Molecular biology reports

authors： Kordi-Tamandani DM,Vaziri S,Dahmardeh N,Torkamanzehi A

更新日期：2013-08-01 00:00:00

abstract：:The complete mitochondrial genome of Pseudochauhanea macrorchis was determined and compared with other monogenean mitochondrial genomes from GenBank. The circular genome was 15,031 bp in length and encoded 36 genes (12 protein-coding genes, two ribosomal RNAs, and 22 transfer RNAs) typically found in flatworms. Struct...

journal_title：Molecular biology reports

authors： Zhang J,Wu X,Xie M,Li A

更新日期：2012-08-01 00:00:00

abstract：:Overexpression of differentiated embryo chondrocyte 1 (DEC1) has been reported to contribute to the cellular differentiation, proliferation, and apoptosis of various cancers. Our previous studies have shown that DEC1 was highly expressed in gastric cancer (GCa) tissues. However, there is no report about the expression...

journal_title：Molecular biology reports

authors： Zheng Y,Shi X,Wang M,Jia Y,Li B,Zhang Y,Liu Q,Wang Y

更新日期：2012-04-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:To gain genetic insights into the protein-rich microalga, the transcriptome of Arthrospira platensis was sequenced using Illumina technology and de novo assembly was carried out. A total of 6023 transcripts were present in the transcriptome among which 4616 transcripts were annotated with specific functions. Gene onto...

journal_title：Molecular biology reports

authors： Kumaresan V,Sannasimuthu A,Arasu MV,Al-Dhabi NA,Arockiaraj J

更新日期：2018-10-01 00:00:00

abstract：:The complete sequence of mitochondrial genome of Siamensis Crocodile (Crocodylus siamensis) is determined by using PCR amplification, clone and primer-walking sequencing methods. The genome is 16836 bp in size, containing 13 protein-coding, 2 ribosomal and 22 transfer RNA genes. The mtDNA genome of Siamensis Crocodile...

journal_title：Molecular biology reports

authors： Ji X,Wu X,Yan P,Amato G

更新日期：2008-06-01 00:00:00

abstract：:Safe harbor loci allow predicable integration of a transgene into the genome without perturbing endogenous gene activity and for decades have been exploited in the mouse to investigate gene function, generate humanised models and create tissue specific reporter and Cre recombinase expressing lines. Herein, we show tha...

journal_title：Molecular biology reports

authors： Browning J,Rooney M,Hams E,Takahashi S,Mizuno S,Sugiyama F,Fallon PG,Kelly VP

更新日期：2020-02-01 00:00:00

abstract：:Resistin is an obesity-related adipokine which has also been implicated in bone metabolism. Therefore, we designed a study to investigate the possible role of resistin gene variation in both obesity and bone mineral density. We included 1,155 individuals from the Odense Androgen Study (663 young subjects and 492 older...

journal_title：Molecular biology reports

authors： Beckers S,Zegers D,Van Camp JK,Boudin E,Nielsen TL,Brixen K,Andersen M,Van Hul W

更新日期：2013-03-01 00:00:00

abstract：:Acute and chronic viral hepatitis infections are corresponding to increase the risk of different types of hematological malignancies especially with leukemia. In this study the serological and molecular markers of hepatitis viruses were evaluated in patients with different types of leukemia in comparing with control g...

journal_title：Molecular biology reports

authors： Mirzaee M,Yaghobi R,Ramzi M,Roshan Nia M

更新日期：2012-02-01 00:00:00