Abstract:
:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate in the process of plant detoxification and morphogenesis. The genome-wide analysis of the MATE genes in potato genome was conducted. At least 48 genes were initially identified and classified into six subfamilies. The chromosomal localization of MATE gene family showed that they could be distributed on 11 chromosomes except chromosome 9. The number of amino acids is 145-616, the molecular weight of proteins is 15.96-66.13 KD, the isoelectric point is 4.97-9.17, and they were located on the endoplasmic reticulum with having 4-13 transmembrane segments. They contain only two parts of the exons and UTR without introns. Some members of the first subfamily of potato MATE gene family are clustered with At2g04070 and they may be related to the transport of toxic compounds such as alkaloids and heavy metal. The function of the members of the second subfamily may be similar to that of At3g23560, which is related to tetramethylammonium transport. Some members of the third subfamily are clustered with At3g59030 and they may be involved in the transport of flavonoids. The fifth subfamily may be related to the transport of iron ions. The function of the sixth subfamily may be similar to that of At4g39030, which is related to salicylic acid transport. There are three kinds of conserved motifs in potato MATE genes, including the motif 1, motif 2, and motif 3. Each motif has 50 amino acids. The number of each motif is different in the gene sequence, of which 45 MATE genes contain at least a motif, but there is no motif in ST0015301, ST0045283, and ST0082336. These results provide a reference for further research on the function of potato MATE genes.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Li Y,He H,He LFdoi
10.1007/s11033-018-4487-ysubject
Has Abstractpub_date
2019-02-01 00:00:00pages
403-414issue
1eissn
0301-4851issn
1573-4978pii
10.1007/s11033-018-4487-yjournal_volume
46pub_type
杂志文章abstract::Evidence is presented to suggest that in chick liver, xanthine dehydrogenase and aldehyde oxidase activities are associated with only one protein species. The results of SDS electrophoresis of the purified material indicate a subunit MW of 120 000. ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00357585
更新日期:1973-08-01 00:00:00
abstract::Spata34 is a testis-specific-expressed gene which exerts diverse functions in testis development. This study intends to examine the expression profiles of Spata34 in postnatal rat testis, and explore its potential roles in cell proliferation in vitro. We found that the mRNA and protein expression levels of Spata34 wer...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-018-4439-6
更新日期:2018-12-01 00:00:00
abstract::Several mechanisms are involved in the loss of cellular integrity and tissue destructions in various brain regions during ischemic insult. The affected brain employs various self-repair mechanisms during the poststroke recovery. Therefore, the current study involves time course changes in different brain regions follo...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05060-7
更新日期:2019-12-01 00:00:00
abstract::The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-0794-2
更新日期:2012-01-01 00:00:00
abstract::The Follicle stimulating hormone beta polypeptide (FSHβ) gene has been investigated as a candidate gene for litter size because of its role in maturation of small and medium follicles into ovulating large follicles. Genes coding follicle stimulating hormone have been found to have significant effects on litter size in...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3789-y
更新日期:2015-02-01 00:00:00
abstract::Resistin is an obesity-related adipokine which has also been implicated in bone metabolism. Therefore, we designed a study to investigate the possible role of resistin gene variation in both obesity and bone mineral density. We included 1,155 individuals from the Odense Androgen Study (663 young subjects and 492 older...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2327-z
更新日期:2013-03-01 00:00:00
abstract::F-box proteins are key components of the ubiquitin (Ub)/26S proteasome pathway that mediates selective degradation of regulatory proteins involved in a wide variety of cellular processes affecting eukaryotic cells. In plants, F-box genes form one of the largest multigene superfamilies and control many important biolog...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0438-y
更新日期:2011-06-01 00:00:00
abstract::A full-length cDNA encoding wheat peroxisomal ascorbate peroxidase (pAPX) was cloned by Suppression Subtractive Hybridization (SSH) and in silico approach. The cDNA was 1027 bp in length and contained a complete ORF of 876 bp, which encodes a protein of 292 amino acid residues. Its deduced amino acids sequence had 84%...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-005-4536-1
更新日期:2006-09-01 00:00:00
abstract::To determine the plasma lipid and lipoprotein profiles and their possible association with the type of β-thalassemia mutation we studied 103 major β-thalassemia patients including 71 children and 32 young adults compared to 102 healthy subjects consisted of 90 children and 12 young healthy adults. The plasma lipid and...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0397-3
更新日期:2011-04-01 00:00:00
abstract::The genes of E. coli are located on a circular chromosome of 4.6 million basepairs. This 1.6 mm long molecule is compressed into a nucleoid to fit inside the 1-2 microm cell in a functional format. To examine the role of DNA supercoiling as nucleoid compaction force we modulated the activity of DNA gyrase by electroni...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1023/a:1020318705894
更新日期:2002-01-01 00:00:00
abstract::AP2/ERF transcription factors play an important role in regulation of the cross-talk between ethylene and jasmonate signaling pathways mediating defense responses of plants to biotic and abiotic stresses. In this study, an AP2/ERF transcription factor gene was isolated and characterized from laticifers of rubber tree ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1146-y
更新日期:2012-04-01 00:00:00
abstract::Haemoglobin meseenger RNA was isolated from spleen erythroïd cells of anaemic rabbits. The mRNA fraction looks quite homogeneous when analyzed by sucrose gradient centrifugation; it sediments in the 9S region. When added to an ascites cell free system, spleen 9S RNA stimulates the incorporation of radioactive leucine ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00357405
更新日期:1973-06-01 00:00:00
abstract::Heparan sulfate proteoglycans (HSPGs) located at the cell surface and in the extracellular matrix of most animal tissues are proteoglycan coreceptors that carry heparan sulfate chains, and play a vital role in infections of many diseases. HSPGs are classified as glypican, syndecan, perlecan and agrin according to diff...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-2340-2
更新日期:2013-03-01 00:00:00
abstract::Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study is...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0497-0
更新日期:2011-08-01 00:00:00
abstract::Gibberellic acid (GA) is involved in the regulation of plant growth and development. We defined GA-stimulated transcript (GAST) gene family and characterized its four members (TaGAST1, 2, 3, and 4) in wheat spikes. Triticum aestivum whole spikes were collected at ten developmental stages and dehulled spikelets were ob...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-016-4077-9
更新日期:2016-12-01 00:00:00
abstract::Mucor circinelloides is a dimorphic fungal model for studying several biological processes including cell differentiation (yeast-mold transitions) as well as biodiesel and carotene production. The recent release of the first draft sequence of the M. circinelloides genome, combined with the availability of analytical m...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3818-x
更新日期:2015-03-01 00:00:00
abstract::We report the characterization of VvIAA9, an auxin/indole-3-acetic acid (Aux/IAA) protein, in grapevine (Vitis vinifera L.). VvIAA9 was expressed abundantly in leaves and berries. VvIAA9 transcription was drastically upregulated from anthesis to onset of ripening (termed véraison), in which berry diameter rapidly incr...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1625-9
更新日期:2012-07-01 00:00:00
abstract::Osteoporosis is a degenerative disease of the skeletal system, and its major complication is fracture that severely influences the living quality of the middle-aged and the aged. The purpose of this study was to investigate the significance of sex hormones and some biochemical indicators related to bone metabolism in ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0187-y
更新日期:2011-02-01 00:00:00
abstract::Various case-control studies have shown association of single nucleotide polymorphism rs12303764(G/T) in ULK1 with crohn's disease. The techniques used in these studies were time consuming, complicated and require sophisticated/expensive instruments. Therefore, in order to overcome these problems, we have developed a ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-016-4087-7
更新日期:2017-02-01 00:00:00
abstract::Metabolic syndrome is an agglomeration of disorders including obesity, diabetes and cardiovascular diseases and characterized as chronic mild inflammation which elevates the circulatory inflammatory markers. This could be due to mitochondrial dysfunction, oxidative stress and hypoxia as a consequence of high fat diet ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-04623-y
更新日期:2019-04-01 00:00:00
abstract::Free cytoplasmic 40S mRNP particles from rat liver were treated with EDTA and separated into two populations of RNP particles with sedimentation maxima of 20S and 35S, respectively. A characteristic set of distinct scRNAs is found for 20S and 35S RNP particles. The sequences of two of the most abundant scRNAs from 20S...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00777475
更新日期:1983-05-01 00:00:00
abstract::The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1915-2
更新日期:2012-12-01 00:00:00
abstract::p53 helps in maintaining genomic stability by undergoing cellular arrest, DNA repair or cellular apoptosis during DNA damage. So, as to find the association of p53Arg 72 Pro towards lung carcinogenesis and overall survival of North Indian lung cancer patients, single nucleotide polymorphic variant (rs1042522) was anal...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-016-4072-1
更新日期:2016-12-01 00:00:00
abstract::BURP domain-containing genes comprise a large plant-specific family, yet the functions are very poorly understood, especially in maize (Zea mays) and sorghum (Sorghum vulgare). In this study, 26 BURP family genes in maize (ZmBURP01-15) and sorghum (SbBURP01-11) were identified including the gene structure, phylogeneti...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0587-z
更新日期:2011-10-01 00:00:00
abstract::Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor sup...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-013-2551-1
更新日期:2013-07-01 00:00:00
abstract::The aim of this study was to determine whether the Glutathione S-transferase M1 (GSTM1) and P1 (GSTP1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). Meta-analysis was performed on the associations between the GSTM1 and GSTP1 null genotypes and RA, and on the association between smoking or seroposit...
journal_title:Molecular biology reports
pub_type: 杂志文章,meta分析
doi:10.1007/s11033-012-1965-5
更新日期:2012-12-01 00:00:00
abstract::The present study examined partial cytochrome b gene sequence of mitochondrial DNA for polymorphism and its suitability to determine the genetic differentiation in wild Labeo rohita. The 146 samples of L. rohita were collected from nine distant rivers; Satluj, Brahmaputra, Son, Chambal Mahanadi, Rapti, Chauka, Bhagira...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1140-4
更新日期:2012-04-01 00:00:00
abstract::Using a combination of bioinformation analysis and Dot blot technique, a gene, designated hereafter as the duck enteritis virus (DEV) UL31 gene (GenBank accession number EF643559), was identified from the DEV CHv genomic library. Then, the UL31 gene was cloned and sequenced, which was composed of 933 nucleotides encod...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-009-9546-y
更新日期:2010-03-01 00:00:00
abstract::It is well-established that an impaired adipose tissue function and morphology caused by a dysregulated gene expression contribute substantially to obesity. Nowadays, animal model studies and in vitro surveys provide evidence for possible roles of HDACs as emerging epigenetic players in the pathogenesis of obesity. Ho...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05431-5
更新日期:2020-05-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERP...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-0877-0
更新日期:2012-02-01 00:00:00