Adipose tissue mRNA expression of HDAC1, HDAC3 and HDAC9 in obese women in relation to obesity indices and insulin resistance.

abstract：:This study investigated the role of the mevalonate pyrophosphate decarboxylase gene in the triterpene biosynthetic pathway of Ganoderma lucidum. The mevalonate pyrophosphate decarboxylase gene (mvd) was isolated using a degenerate primer-PCR technique. An analysis of the Gl-mvd transcription profile revealed a positiv...

journal_title：Molecular biology reports

authors： Shi L,Qin L,Xu Y,Ren A,Fang X,Mu D,Tan Q,Zhao M

更新日期：2012-05-01 00:00:00

abstract：:Circular RNA (circRNA), a novel type of non-coding RNA that consists of a circular loop, has been demonstrated to act as a "sponge" for microRNAs (miRNAs). However, the role of circRNAs in keloid remains unknown. In this study, we investigated circRNA expression profiles in keloid to identify potential diagnostic and ...

journal_title：Molecular biology reports

authors： Shi J,Yao S,Chen P,Yang Y,Qian M,Han Y,Wang N,Zhao Y,He Y,Lyu L,Lu D

更新日期：2020-01-01 00:00:00

abstract：:As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, sc...

journal_title：Molecular biology reports

authors： Chen B,Pan W,Zhang L,Liu J,Ouyang H,Nie Q,Zhang X

更新日期：2014-10-01 00:00:00

abstract：:Keratin-associated proteins (KAPs) are structural components of wool and variation in them may affect wool characteristics. In this study, we used PCR-SSCP to analyse the ovine KAP6 family which encodes glycine and tyrosine-rich KAPs. Five unique PCR-SSCP patterns were detected in the 250 sheep investigated. Between t...

journal_title：Molecular biology reports

authors： Gong H,Zhou H,Hickford JG

更新日期：2011-01-01 00:00:00

abstract：:Despite advantageous antitumor properties of doxorubicin, the considerable cytotoxicity of this chemotherapeutic agent has made it necessary to develop combination treatment strategies. The aim of the current study was to investigate the possible synergism between dendrosomal nanocurcumin (DNC) and doxorubicin in elic...

journal_title：Molecular biology reports

authors： Mahjoub MA,Bakhshinejad B,Sadeghizadeh M,Babashah S

更新日期：2017-08-01 00:00:00

abstract：:A copper(II) complex containing aspartame (APM) as ligand, Cu(APM)2Cl2·2H2O, was synthesized and characterized. In vitro binding interaction of this complex with human serum albumin (HSA) was studied at physiological pH. Binding studies of this complex with HSA are useful for understanding the Cu(APM)2Cl2·2H2O-HSA int...

journal_title：Molecular biology reports

authors： Shahabadi N,Khodaei MM,Kashanian S,Kheirdoosh F,Filli SM

更新日期：2014-05-01 00:00:00

abstract：:Mucopolysaccharidosis IV A (MPS IV A) is a lysosomal storage disease produced by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme. Although genotype-phenotype correlations have been reported, these approaches have not enabled to establish a complete genotype-phenotype correlation, and they ha...

journal_title：Molecular biology reports

authors： Olarte-Avellaneda S,Rodríguez-López A,Alméciga-Díaz CJ,Barrera LA

更新日期：2014-11-01 00:00:00

abstract：:Random amplified polymorphic DNA (RAPD) and microsatellite markers were applied to evaluate the genetic variation in endemic and endangered yellow catfish, Horabagrus brachysoma sampled from three geographic locations of Western Ghat, South India river systems. In RAPD, of 32 10-mer RAPD primers screened initially, 10...

journal_title：Molecular biology reports

authors： Abdul Muneer PM,Gopalakrishnan A,Musammilu KK,Mohindra V,Lal KK,Basheer VS,Lakra WS

更新日期：2009-09-01 00:00:00

abstract：:The interleukin (IL)-1β-511 C/T polymorphism has been shown to be functional and to contribute to the risk of gastric cancer. However, the relationship between the IL-1β-511 C/T polymorphism and gastric carcinogenesis remains inconclusive. A systematical electronic search was conducted of the MEDLINE, EMBASE, and CENT...

journal_title：Molecular biology reports

authors： Park MJ,Hyun MH,Yang JP,Yoon JM,Park S

更新日期：2015-01-01 00:00:00

abstract：:The complete mitochondrial genome of Zhikong scallop Chlamys farreri is 21,695 bp in length and contains 12 protein-coding genes (the atp8 gene is absent, as in most bivalves), 2 ribosomal RNA genes, and 22 transfer RNA genes. The heavy strand has an overall A+T content of 58.7%. GC and AT skews for the mt genome of C...

journal_title：Molecular biology reports

authors： Xu K,Kanno M,Yu H,Li Q,Kijima A

更新日期：2011-06-01 00:00:00

abstract：:Geranylgeranyl diphosphate synthase (GGPPS) [EC 2.5.1.29] catalyzes the biosynthesis of geranylgeranyl diphosphate (GGPP), which is a key precursor for diterpenes such as taxol. Herein, a full-length cDNA encoding GGPPS (designated as CgGGPPS) was cloned and characterized from hazel (Corylus avellana L. Gasaway), a ta...

journal_title：Molecular biology reports

authors： Wang Y,Miao Z,Tang K

更新日期：2010-10-01 00:00:00

abstract：:As-NUPR1, a stress-related protein, plays an important role in post-diapause during embryonic development in the brine shrimp Artemia sinica. In the present study, successful expression of As-NUPR1 from the cDNA sequence isolated from A. sinica was demonstrated using a prokaryotic expression system. The recombinant pr...

journal_title：Molecular biology reports

authors： Zhang R,Yao F,Cheng C,Chen Y,Lv Y,Li Z,Zhao N,Wang T,Xin W,Zou X,Hou L

更新日期：2014-05-01 00:00:00

abstract：:An extensive study on spontaneous and 5-Fluorodeoxyuridine induced fragile sites identified Xq31 in cattle (Bos taurus) and (Xq24, Xq26) in sheep (Ovis aries) in addition to several autosomal fragile sites (under publication). A ZOO-FISH study using three cloned human fragile-X probes with CCG/CGG(n) trinucleotide rep...

journal_title：Molecular biology reports

authors： Ali A,Thomsen PD,Babar ME

更新日期：2009-03-01 00:00:00

abstract：:Histone H1 is know to play a role in the formation and maintenance of higher-order chromatin structure. It has been recently suggested that the linker histone might be also involved in the regulation of the activity of individual genes. If H1 is a regulatory factor in eukaryotic gene transcription, it should possess s...

journal_title：Molecular biology reports

authors： Zlatanova J,Yaneva J

更新日期：1991-02-01 00:00:00

abstract：:Schizophrenia is a chronic and neuropsychiatric disease that affects about 0.5-1% of the world's population. An increase in dopamine and dopamine D2 receptor (DRD2) gene products has been well described in schizophrenic patients. Several groups have studied the relationship between dopaminergic hyperactivity and cellu...

journal_title：Molecular biology reports

authors： Kurt H,Dikmen M,Basaran A,Yenilmez C,Ozdemir F,Degirmenci I,Gunes HV,Kucuk MU,Mutlu F

更新日期：2011-02-01 00:00:00

abstract：:Endometriosis is a polygenic and multifactorial gynecology situation which might be associated with angiogenesis. In the current study we assess the role of vascular endothelial growth factor (VEGF) - 2578 A/C, and + 936 C/T polymorphisms in susceptibility to endometriosis and checking the expression of VEGF mRNA in e...

journal_title：Molecular biology reports

authors： Rashidi BH,Sarhangi N,Aminimoghaddam S,Haghollahi F,Naji T,Amoli MM,Shahrabi-Farahani M

更新日期：2019-06-01 00:00:00

abstract：:It is widely accepted that protein phosphorylation is a major control event in regulating cell cycle. In the present study, a novel M-phase phosphoprotein 6 (MPP6) was identified from black tiger shrimp Penaeus monodon (designated as PmMPP6) by cDNA library and RACE approaches. The full-length cDNA of PmMPP6 was of 69...

journal_title：Molecular biology reports

authors： Zhou J,Qiu L,Jiang S,Zhou F,Huang J,Yang L,Su T,Zhang D

更新日期：2013-02-01 00:00:00

abstract：:In plants, pathogenesis-related 1 protein (PR1) is considered as important defense protein. The production and accumulation of PR proteins in plants are one of the important responses to several biotic and abiotic stresses. In this regard, PR1 gene was isolated from Triticum turgidum ssp durum and was named as TdPR1.2...

journal_title：Molecular biology reports

authors： Ghorbel M,Zribi I,Missaoui K,Drira-Fakhfekh M,Azzouzi B,Brini F

更新日期：2020-12-13 00:00:00

abstract：:An important alternative source of fish oil is its production by plants through metabolic engineering. To produce eicosapentaenoic acid (EPA, 20:5n-3) in peanut through the alternative Δ8-pathway, a plant expression vector containing five heterologous genes driven by the constitutive 35S promoter respectively, namely,...

journal_title：Molecular biology reports

authors： Wang C,Qing X,Yu M,Sun Q,Liu F,Qi B,Li X

更新日期：2019-02-01 00:00:00

abstract：:The immunity and health status of ornamental fish is an important aspect, as they are kept in a confined environment and various stressful conditions which lead to depletion of overall colourful appearance and mortality. The carotenoids can act as immunity boosters in captive aquarium system and may be supplemented in...

journal_title：Molecular biology reports

authors： Tripathy PS,Khatei A,Parhi J,Choudhury TG,Sahoo L,Mandal SC

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to elucidate the effects of sex hormones on activity of the ABCG2 promoter in different cell lines. T47D cells and BeWo cells were used as models for ABCG2-expressing cell lines, and luciferase assays using ABCG2 promoter-luciferase constructs were performed. It was shown that progesterone in...

journal_title：Molecular biology reports

authors： Yasuda S,Kobayashi M,Itagaki S,Hirano T,Iseki K

更新日期：2009-09-01 00:00:00

abstract：:Protein profile of the skeletal muscle of Takifugu rubripes, a kind of pufferfish, was carried out with two-dimensional polyacrylamide gel electrophoresis (2-DE). Among the 112 protein spots detected in a silver-stained 2-D polyacrylamide gel, 33 were analyzed by Matrix Assisted Laser Desorption Ionisation tandem time...

journal_title：Molecular biology reports

authors： Lu J,Zheng J,Liu H,Li J,Chen H,Chen K

更新日期：2010-06-01 00:00:00

abstract：:Growth hormone-releasing hormone receptor (GHRHR) has important functions in the regulation of the growth hormone axis and the development and proliferation of pituitary somatotropes. Moreover, some mutations in mouse GHRHR can induce the dwarfism. The objective of this paper is to reveal the association of GHRHR with...

journal_title：Molecular biology reports

authors： Zhang CF,Chen H,Zhang ZY,Zhang LZ,Yang DY,Qu YJ,Hua LS,Zhang B,Hu SR

更新日期：2012-12-01 00:00:00

abstract：:Sulfonamide derivatives, such as sulfadiazine (SD) are used as antibiotics and, very recently, anti-amyloid properties of these have been reported. We have evaluated binding of SD with bovine serum albumin (BSA) followed by unfolding of protein. Studies were accomplished at physiological conditions of temperature (37 ...

journal_title：Molecular biology reports

authors： Al-Lohedan HA,Sajih Ali M

更新日期：2013-11-01 00:00:00

abstract：:In view of high mortality associated with coronary artery disease (CAD), development of an early predicting tool will be beneficial in reducing the burden of the disease. The database comprising demographic, conventional, folate/xenobiotic genetic risk factors of 648 subjects (364 cases of CAD and 284 healthy controls...

journal_title：Molecular biology reports

authors： Naushad SM,Hussain T,Indumathi B,Samreen K,Alrokayan SA,Kutala VK

更新日期：2018-10-01 00:00:00

abstract：:The circular dichroism spectra of poly(dG). poly(dC) have been studied as a function of pH in 0.15 M NaCl solution. Acid titration to pH 2.5 showed two transitions, one around pH 5, the second below pH 3. These transitions are disproportionation reactions and are not due to the dissociation of the complexes. Alkaline ...

journal_title：Molecular biology reports

authors： Thiele D,Sarocchi MT,Guschlbauer W,Marck C

更新日期：1973-10-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is an aggressive BC subtype characterized by HER2 overexpression/amplification. Genomic alterations of HER2 and others have been reported to be associated with, HER2 overexpression and prediction of trastuzumab-response. Here, we aimed at ide...

journal_title：Molecular biology reports

authors： Singla H,Kaur RP,Shafi G,Vashistha R,Banipal RPS,Kumar V,Munshi A

更新日期：2019-02-01 00:00:00

abstract：:Lipoprotein-associated phospholipase A2 (LP-PLA2) may play an important role in the pathophysiology of coronary heart disease (CHD). The polymorphism of LP-PLA2 gene caused LP-PLA2 enzyme activity depressing or lost. But there is not a definite conclusion for the association of between the LP-PLA2 gene polymorphism an...

journal_title：Molecular biology reports

authors： Zheng GH,Chen HY,Xiong SQ,Chu JF

更新日期：2011-08-01 00:00:00

abstract：:In spite of much awareness, diabetes mellitus continues to remain one of major reasons for mortality and morbidity rate all over the globe. Free radicals cause oxidative stress which is responsible for causing diabetes. The recent advancements in elucidation of ARE/keap1/Nrf2 pathway can help in better understanding o...

journal_title：Molecular biology reports

authors： Behl T,Kaur I,Sehgal A,Sharma E,Kumar A,Grover M,Bungau S

更新日期：2021-01-03 00:00:00

abstract：:Rheumatoid arthritis (RA) is considered as a long-term autoimmune disorder. Gene polymorphism and oxidative stress might be involved in the pathogenesis of the disease. We aimed to determine the association between PON-1L55M polymorphism and its effects on inflammatory markers such as anti-cytroline circulated-peptide...

journal_title：Molecular biology reports

authors： Tanhapour M,Shahmohamadnejad S,Vaisi-Raygani A,Kiani A,Shakiba Y,Rahimi Z,Bahrehmand F,Shakiba E,Vaisi-Raygani AA,Alibakhshi R,Eivazi A,Pourmotabbed T

更新日期：2019-02-01 00:00:00