Resistin polymorphisms show associations with obesity, but not with bone parameters in men: results from the Odense Androgen Study.

abstract：:A Cys2/His2-type zinc finger protein gene, DgZFP, was isolated from chrysanthemum by rapid amplification of cDNA ends (RACE) approach. The DgZFP encodes a protein of 211 amino acids residues with a calculated molecular mass of 22.9 kDa and theoretical isoelectric point is 8.59. DgZFP contains two Cys2/His2-type zinc f...

journal_title：Molecular biology reports

authors： Liu QL,Xu KD,Ma N,Zeng L,Zhao LJ

更新日期：2010-02-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:Late-embryogenesis abundant (LEA) proteins have been reported to be closely correlated with the acquisition of desiccation tolerance during seed development and response of plant to drought, salinity, and freezing, etc. In this study, a LEA gene, CarLEA4 (GenBank accession no. GU247511), was isolated from chickpea bas...

journal_title：Molecular biology reports

authors： Gu H,Jia Y,Wang X,Chen Q,Shi S,Ma L,Zhang J,Zhang H,Ma H

更新日期：2012-04-01 00:00:00

abstract：:The response of the respiratory subsystem of oxidative phosphorylation to the environmental pollutant, 2,2',5,5'-tetrachlorobiphenyl (2,2',5,5'-TCB) was investigated by modular kinetic approach. The effects of 20 microM 2,2',5,5'-TCB on the activity of the respiratory chain modules in rat liver mitochondria oxidizing ...

journal_title：Molecular biology reports

authors： Mildaziene V,Nauciene Z,Krab K

更新日期：2002-01-01 00:00:00

abstract：:Large-scale random cDNA sequencing projects have been started for several organisms and are a valuable tool for the analysis of quantitative and qualitative aspects of gene expression. However, the reliability of the obtained data is limited as most of the clones are only partially analysed on one strand. As a consequ...

journal_title：Molecular biology reports

authors： Braun HP

更新日期：1996-01-01 00:00:00

abstract：:The treatment of anaplastic astrocytoma (AA) is controversial. New chemotherapeutic approaches are needed for AA treatment. Temozolomide (TMZ) is one of the chemotherapeutic drugs for the treatment of AA. The cytotoxic effects of TMZ can be removed by the MGMT (O(6)-methylguanine-DNA methyltransferase) enzyme. Then, c...

journal_title：Molecular biology reports

authors： Ugur HC,Taspinar M,Ilgaz S,Sert F,Canpinar H,Rey JA,Castresana JS,Sunguroglu A

更新日期：2014-02-01 00:00:00

abstract：:Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an ex...

journal_title：Molecular biology reports

authors： Gismondi A,Nanni V,Monteleone V,Colao C,Di Marco G,Canini A

更新日期：2021-01-01 00:00:00

abstract：:The investigation was carried out to analyse the genetic polymorphism and gene expression of ATP1A1 gene in four different Indian goat breeds by using high resolution melting (HRM) and real time-PCR. ATPase is electro-genic ion pump which is maintains the balance of sodium and potassium ions in animal cells. The trans...

journal_title：Molecular biology reports

authors： Kaushik R,Goel A,Rout PK

更新日期：2019-10-01 00:00:00

abstract：:Complexity is one of the hallmarks that applies to C2H2 type zinc finger proteins (ZFPs). Structurally distinct clusters of zinc finger modules define an extremely large superfamily of nucleic acid binding proteins with several hundred, perhaps thousands of different members in vertebrates. Recent discoveries have pro...

journal_title：Molecular biology reports

authors： Pieler T,Bellefroid E

更新日期：1994-07-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:In the Eastern province of Saudi Arabia, thalassemia is highly common. Data on the effect of alpha globin gene variation on the concentration of iron on transfusion dependent Saudis are scanty. A total of 166 transfusions dependent β-thalassemia were included in this study to understand association between the alpha g...

journal_title：Molecular biology reports

authors： AbdulAzeez S,Almandil NB,Naserullah ZA,Al-Jarrash S,Al-Suliman AM,ElFakharay HI,Borgio JF

更新日期：2020-01-01 00:00:00

abstract：:Covalent modification/demodification cycles are common in metabolism. When the modification and demodification steps are carried out by two independent enzymes, the degree of modification can be ultrasensitive to the total concentration of either catalyst. We recently showed that the degree of modification of a target...

journal_title：Molecular biology reports

authors： Ortega F,Ehrenberg M,Acerenza L,Westerhoff HV,Mas F,Cascante M

更新日期：2002-01-01 00:00:00

abstract：:Sepsis is one of the major health problems all over the world. Early diagnostic of sepsis is an attractive strategy to decrease the mortality of septic patients. However, an effective biomarker that fulfills all the necessary requirements for the accurate characterization of sepsis is still unavailable until now. In t...

journal_title：Molecular biology reports

authors： Liu J,Li J,Deng X

更新日期：2014-05-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:We examined genetic associations of previously identified sequence variants with bone mineral density and their heterogeneity by gender. Large-scale cohort data were used including a total of 8,419 subjects (4,034 males and 4,385 females) from the Korean Association REsource (KARE) cohort. Bone speed of sound (SOS) va...

journal_title：Molecular biology reports

authors： Woo J,Kim Y,Lee C

更新日期：2012-03-01 00:00:00

abstract：:Control of polypeptide synthesis plays an important role in cell proliferation and translation rates generally reflect the growth state of the cultured eukaryotic cell. Physiological regulation of protein synthesis is almost always exerted at the level of polypeptide chain initiation, with the binding of mRNA to the s...

journal_title：Molecular biology reports

authors： Morley SJ

更新日期：1994-05-01 00:00:00

abstract：:Human Wharton's jelly mesenchymal stem cells (hWJSCs) are multipotent stem cells that could be aggregated into 3D spherules. ITGA4 and ITGA5 genes encode α4 and α5 subunits of integrins, respectively. In this study, we analyzed expression levels of ITGA4 and ITGA5 gene mRNAs in undifferentiated and 3D spherules formin...

journal_title：Molecular biology reports

authors： Mostafavi-Pour Z,Ashrafi MR,Talaei-Khozani T

更新日期：2018-06-01 00:00:00

abstract：:The binding of acridine orange and ethidium bromide to rat liver chromatin increases by 30% one hour after partial hepatectomy, returns to the control level by the second hour and increases again by the sixth hour. The changes described were found in investigations carried out on whole cells, on isolated nuclei, and o...

journal_title：Molecular biology reports

authors： Sondore OY,Fedoseeva GE,Kadyckov VA,Zelenin AV

更新日期：1978-10-16 00:00:00

abstract：:Mucor circinelloides is a dimorphic fungal model for studying several biological processes including cell differentiation (yeast-mold transitions) as well as biodiesel and carotene production. The recent release of the first draft sequence of the M. circinelloides genome, combined with the availability of analytical m...

journal_title：Molecular biology reports

authors： Valle-Maldonado MI,Jácome-Galarza IE,Gutiérrez-Corona F,Ramírez-Díaz MI,Campos-García J,Meza-Carmen V

更新日期：2015-03-01 00:00:00

abstract：:Adenylosuccinate lyase (ADSL) is a bifunctional enzyme acting in de novo purine synthesis and purine nucleotide recycling. In the present study, we have constructed a grass carp (Ctenopharyngodon idella) intestinal cDNA library that has over 2.3 × 10(5) primary clones. An expressed sequence tag (EST) of grass carp ade...

journal_title：Molecular biology reports

authors： Yuan T,Gu JR,Gu WB,Wu J,Ge SR,Xu H

更新日期：2011-03-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...

journal_title：Molecular biology reports

authors： Wang W,Gao J,Wang J,Liu C,Meng Y

更新日期：2012-12-01 00:00:00

abstract：:45S ribosomal precursor RNA and large heterogeneous RNA molecules (greater than 45S) extracted from human leukemic cells were incubated in vitro with purified RNase III, which specifically attacks double-helical RNA regions. About 50% of the ribosomal precursor was cleaved into two major fragments sedimenting at 28S a...

journal_title：Molecular biology reports

authors： Torelli UL,Ferrari S,Torelli GM,Cadossi R,Ferrari S,Montagnani G,Narni F

更新日期：1977-12-01 00:00:00

abstract：:Deprivation of cytokines induces cell cycle arrest and apoptosis in cytokine-dependent hematopoietic progenitors. Previous studies have indicated that in Baf-3, interleukin (IL)-3-dependent cells, apoptosis is caused predominantly by Bim, a BH3-only cell death activator that belongs to the Bcl-2 superfamily. Because B...

journal_title：Molecular biology reports

authors： Matsui H,Shinjyo T,Inaba T

更新日期：2005-06-01 00:00:00

abstract：:Disorders in the proliferation and apoptosis of thyrocytes may induce goitre, adenoma and carcinoma in the thyroid. The Wnt/beta-catenin pathway has been demonstrated to be involved in the regulation of cell proliferation, differentiation and apoptosis in various cell lines. The regulatory mechanism on the proliferati...

journal_title：Molecular biology reports

authors： Chen G,Jiang Q,You Z,Yao J,Mou L,Lin X,Shen X,You T,Lin Q,Wen J,Lin L

更新日期：2010-07-01 00:00:00

abstract：:BAP31 is a ubiquitously expressed integral membrane protein of the endoplasmic reticulum. BAP31 is involved in various biological and molecular processes, including protein transport, viral processing, apoptosis signaling, MHC 1 antigen processing and presentation, mitochondria and ER calcium regulation, and proteasom...

journal_title：Molecular biology reports

authors： Namusamba M,Li Z,Zhang Q,Wang C,Wang T,Wang B

更新日期：2021-01-13 00:00:00

abstract：:Interindividual variability exists in statin lipid-lowering response, partially attributed to genetic factors. Organic anion-transporting polypeptide 1B1 (OATP1B1) encoded by SLCO1B1 gene (solute carrier organic anion transporter family member 1B1) facilitates hepatic uptake of simvastatin and atorvastatin. SLCO1B1 po...

journal_title：Molecular biology reports

authors： Giannakopoulou E,Ragia G,Kolovou V,Tavridou A,Tselepis AD,Elisaf M,Kolovou G,Manolopoulos VG

更新日期：2014-07-01 00:00:00

abstract：:Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence, this study evaluated the cardioprotective mechanism(s) of Morin against isoproterenol induced myocardial necrosis in rats. Male albino Wistar rats were divided ...

journal_title：Molecular biology reports

authors： Verma VK,Malik S,Narayanan SP,Mutneja E,Sahu AK,Bhatia J,Arya DS

更新日期：2019-02-01 00:00:00

abstract：:Amerindians immigrated to Madrid (Spain) region are about 10% of the present day population. Amerindians are believed to be the first American inhabitants, before Na-Dene speakers, Aleuts and Eskimo. They may initially have arrived to America from Siberia and also from other parts of Pacific Sea (South Asia, Polynesia...

journal_title：Molecular biology reports

authors： Parga-Lozano C,Rey-Medrano D,Gomez-Prieto P,Areces C,Moscoso J,Abd-El-Fatah-Khalil S,Moreno E,Arnaiz-Villena A

更新日期：2011-04-01 00:00:00

abstract：:Complementary DNA to mouse globin mRNA was prepared using viral reverse transcriptase. Molecular hybridisation of this cDNA to Friend virus RNA demonstrates the absence of globin gene sequences. ...

journal_title：Molecular biology reports

authors： Pragnell IB,Gilmour RS

更新日期：1973-12-01 00:00:00

abstract：:Coactivator CBP (CREB-binding protein) has been implicated in the regulation of transcription for all signal transducer and activator of transcription factors (STATs); however, the mechanism remains unclear. Using yeast two-hybrid screening and immunoprecipitation techniques, we investigated the direct interaction of ...

journal_title：Molecular biology reports

authors： Zhang M,Fu Z,Tian D,Liu E,Dai J,Wang L

更新日期：2011-10-01 00:00:00