Abstract：
:45S ribosomal precursor RNA and large heterogeneous RNA molecules (greater than 45S) extracted from human leukemic cells were incubated in vitro with purified RNase III, which specifically attacks double-helical RNA regions. About 50% of the ribosomal precursor was cleaved into two major fragments sedimenting at 28S and 32S respectively. A limited number of cleavages was also introduced in about 40% of heterogeneous RNA molecules sedimenting faster than 45S, causing a partial 'shift' to a polydisperse distribution in the 10S-45S range.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Torelli UL,Ferrari S,Torelli GM,Cadossi R,Ferrari S,Montagnani G,Narni Fdoi
10.1007/BF00808381subject
Has Abstractpub_date
1977-12-01 00:00:00pages
403-11issue
6eissn
0301-4851issn
1573-4978journal_volume
3pub_type
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