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Comparative properties of rat liver chromatin in situ and in vitro at early stages after partial hepatectomy.

Abstract：

:The binding of acridine orange and ethidium bromide to rat liver chromatin increases by 30% one hour after partial hepatectomy, returns to the control level by the second hour and increases again by the sixth hour. The changes described were found in investigations carried out on whole cells, on isolated nuclei, and on chromatin preparation in vitro. Increased ligand binding disappears after the treatment of the one-hour chromatin with a 0.3 M NaCl solution, but such a treatment does not change the binding of ligands to chromatin obtained six hours after hepatectomy. The one-hour chromatin is characterized by elongation of distances between individual nucleosomes whereas the two-hour chromatin is the same as in control.

journal_name

Mol Biol Rep

journal_title

Molecular biology reports

authors

Sondore OY,Fedoseeva GE,Kadyckov VA,Zelenin AV

doi

10.1007/BF00777513

subject

Has Abstract

pub_date

1978-10-16 00:00:00

pages

137-41

issue

3

eissn

0301-4851

issn

1573-4978

journal_volume

4

pub_type

杂志文章

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