Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma.

abstract：:Kawasaki disease (KD) is a multi-systemic vasculitis which preferentially affects infants and children. A single nucleotide polymorphism (rs28493229) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) was identified to be associated with the increased risk of KD; however, in more recent studies associations have b...

journal_title：Molecular biology reports

authors： Lou J,Xu S,Zou L,Zhong R,Zhang T,Sun Y,Lu X,Liu L,Li C,Wang L,Xiong G,Wang W,Gong F,Wu J

更新日期：2012-12-01 00:00:00

abstract：:Two DREB-like genes, designated as DmDREBa and DmDREBb, were isolated from chrysanthemum by RACE approach. The DmDREBa and DmDREBb genes encoded proteins of 191 and 185 amino acid residues with the predicted molecular mass of 21.66 and 20.99 kDa, respectively. Both DmDREBs proteins comprised a typical EREBP/AP2 domain...

journal_title：Molecular biology reports

authors： Yang Y,Wu J,Zhu K,Liu L,Chen F,Yu D

更新日期：2009-01-01 00:00:00

abstract：:Histone H1 is know to play a role in the formation and maintenance of higher-order chromatin structure. It has been recently suggested that the linker histone might be also involved in the regulation of the activity of individual genes. If H1 is a regulatory factor in eukaryotic gene transcription, it should possess s...

journal_title：Molecular biology reports

authors： Zlatanova J,Yaneva J

更新日期：1991-02-01 00:00:00

abstract：:In spite of much awareness, diabetes mellitus continues to remain one of major reasons for mortality and morbidity rate all over the globe. Free radicals cause oxidative stress which is responsible for causing diabetes. The recent advancements in elucidation of ARE/keap1/Nrf2 pathway can help in better understanding o...

journal_title：Molecular biology reports

authors： Behl T,Kaur I,Sehgal A,Sharma E,Kumar A,Grover M,Bungau S

更新日期：2021-01-03 00:00:00

abstract：:The Rv3203 (LipV) of Mycobacterium tuberculosis (Mtb) H37Rv, is annotated as a member of Lip family based on the presence of characteristic consensus esterase motif ‘GXSXG’. In vitro culture studies of Mtb H37Ra indicated that expression of Rv3203 gene was up-regulated during acidic stress as compared to normal wherea...

journal_title：Molecular biology reports

authors： Singh G,Arya S,Narang D,Jadeja D,Singh G,Gupta UD,Singh K,Kaur J

更新日期：2014-01-01 00:00:00

abstract：:Autoantibodies directed to a variety of cellular antigens and organelles are a feature of autoimmune diseases. They have proven useful in a clinical setting to establish diagnosis, estimate prognosis, follow disease progression, alter therapy, and initiate new investigations. Cellular and molecular biologists have use...

journal_title：Molecular biology reports

authors： Rattner JB,Mack GJ,Fritzler MJ

更新日期：1998-07-01 00:00:00

abstract：:The aim of this study was to characterise the effects of ischemic preconditioning (IP) on heart function parameters (ΔST and ΔT), activities of serum creatine kinase (CK), lactate dehydrogenase (LDH), and levels of serum nitric oxide (NO), malondialdehyde (MDA), and myocardium Caspase-3 mRNA, SOCS-1, SOCS-3, tumor nec...

journal_title：Molecular biology reports

authors： Ma J,Qiao Z,Xu B

更新日期：2013-10-01 00:00:00

abstract：:The rapid progress made over the last 10 years in the identification of individual autoantigens and in the localization of the epitopes involved, has resulted in a parallel reduction in the complexity of the antigen required for the detection of autoantibodies. The ability to use synthetic peptides as antigens is a re...

journal_title：Molecular biology reports

authors： Elkon KB

更新日期：1992-06-01 00:00:00

abstract：:Telomeres have lately received considerable attention in the development of tree species. Normal somatic cells have limited replicative capacity and telomeres get shorten with each round of DNA replication. For broad-leaved tree species, to determine what changes happen to their somatic cells in its annual development...

journal_title：Molecular biology reports

authors： Song H,Liu D,Chen X,Ying Z,Zhang B,Li F,Lu H

更新日期：2010-02-01 00:00:00

abstract：:As a paired class homeodomain transcription factor, mutations of PROP1 (Prophet of POU1F1) are responsible for deficiencies of GH, PRL, TSH, LH and FSH. Regarding mutations of GH, PRL, and POU1F1 genes significantly associating with different production traits, PROP1 gene is a novel important candidate gene for detect...

journal_title：Molecular biology reports

authors： Lan X,Pan C,Zhang L,Zhao M,Zhang C,Lei C,Chen H

更新日期：2009-11-01 00:00:00

abstract：:Three members of Brassica napus TRANSPARENT TESTA 2 (BnTT2) gene family encoding potential R2R3-MYB regulatory proteins of proanthocyanidin biosynthesis were isolated. BnTT2-1, BnTT2-2, and BnTT2-3 are 1102 bp with two introns, and have a 938-bp full-length cDNA with a 260 amino acid open reading frame. They share 98....

journal_title：Molecular biology reports

authors： Wei YL,Li JN,Lu J,Tang ZL,Pu DC,Chai YR

更新日期：2007-06-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...

journal_title：Molecular biology reports

authors： Wang W,Gao J,Wang J,Liu C,Meng Y

更新日期：2012-12-01 00:00:00

abstract：:Schizophrenia is one of the neuropathological disorders, which are associated with dopamine and its receptors. In recent years, it has been shown that mRNA of D3, D4 and D5 dopamine receptor (DRD3, DRD4, DRD5) subtypes is expressed in human peripheral blood lymphocytes (PBL). A total 55 schizophrenic patients and 51 h...

journal_title：Molecular biology reports

authors： Urhan-Kucuk M,Erdal ME,Ozen ME,Kul S,Herken H

更新日期：2011-04-01 00:00:00

abstract：:The phosphoenolpyruvate (PEP) carboxylase is regulated at the levels of transcription and post-translation in C4 plants in light and abundantly accumulates in leaf mesophyll cells. We report here developmental and photosynthetic regulation of stably accumulated Bacillus thuringiensis δ-endotoxin under the control of P...

journal_title：Molecular biology reports

authors： Khan MS,Ali S,Iqbal J

更新日期：2011-04-01 00:00:00

abstract：:Because of the importance of androgens to prostate cancer (PCa) development, several candidate genes along androgen pathway have been under intensive study. Given the role of the molecular chaperone HSP70 in the regulation of the androgen receptor (AR) transactivation function, we first chose to explore the associatio...

journal_title：Molecular biology reports

authors： Sfar S,Saad H,Mosbah F,Chouchane L

更新日期：2008-09-01 00:00:00

abstract：:Immense body of evidence indicates that dysfunction of immune system is implicated in the etiology of schizophrenia. The immune theory of schizophrenia is supported by alterations in cytokine profile in the brain and peripheral blood. Given the strong genetic background of schizophrenia, it might be assumed that aberr...

journal_title：Molecular biology reports

authors： Frydecka D,Misiak B,Beszlej JA,Karabon L,Pawlak-Adamska E,Tomkiewicz A,Partyka A,Jonkisz A,Kiejna A

更新日期：2013-10-01 00:00:00

abstract：:Correct classification of genomic variants causing potentially aberrant splicing is of utmost importance for patient management, especially in clinically actionable genes such as BRCA1/2. In this article, we report molecular evaluation of the BRCA1 c.439T>C (rs794727800, p.Leu147=) variant based on RNA of a patient su...

journal_title：Molecular biology reports

authors： Minucci A,Mazzuccato G,D'Indinosante M,Di Nardo L,Concolino P,De Bonis M,Urbani A,Scambia G,Fagotti A,Capoluongo E

更新日期：2020-02-01 00:00:00

abstract：:ATP-binding cassette transporter A1 (ABCA1) modulates plasma levels of high density lipoprotein (HDL), a cardiovascular protecting factor. Tree shrew was considered to be an animal protected from atherosclerosis characterized by high proportion of HDL in plasma. The cDNA clones and expression of tree shrew ABCA1 was i...

journal_title：Molecular biology reports

authors： Zeng WW,Zhou B,Liu HR,Sun GT,Chen BS

更新日期：2009-03-01 00:00:00

abstract：:Breast cancer is the most common cancer type and the second cause of cancer death in women. Different mechanisms are contributed to the initiation and progression of the breast cancer. OCC-1 and APPL2 neighboring genes located in 12q.23.3 human chromosome region are related to colorectal cancer. Here, we intended to i...

journal_title：Molecular biology reports

authors： Ghalaei A,Kay M,Zarrinfam S,Hoseinpour P,Behmanesh M,Soltani BM

更新日期：2018-12-01 00:00:00

abstract：:We report here a cDNA and its deduced amino acid sequence encoding a cathepsin D-like, aspartic protease from Chlamys farreri (denoted as CfCD) by expressed sequence tag and rapid amplification of cDNA ends techniques. The cDNA of CfCD consisted of 1,810 nucleotides with a canonical polyadenylation signal sequence AAT...

journal_title：Molecular biology reports

authors： Li C,Zhang H,Li L,Song L

更新日期：2010-03-01 00:00:00

abstract：:In a meritorious effort H. de Rothschild compiled in 1899 all publications on mammary gland development and milk--a grand total of 8375 [1]. In the preface to this publication Duclaux states: 'Such a discrepancy between the tremendous efforts and the paltriness of the results--hundreds of scientists and thousands of r...

journal_title：Molecular biology reports

authors： Hennighausen L

更新日期：1997-08-01 00:00:00

abstract：:Killer cell immunoglobulin like receptor genes expressed by the natural killer cells and T cells of some subclasses are one of the very diversity and complex gene families on chromosome 19q13.4 which play key developmental role in the fight against viral infections, malignantly transformed cells and so on in the first...

journal_title：Molecular biology reports

authors： Wang HD,Jin XY,Guo YX,Zhang Q,Zhang YW,Wang X,Zhu BF

更新日期：2019-02-01 00:00:00

abstract：:The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...

journal_title：Molecular biology reports

authors： Zhang XM,Jing YP,Jia MY,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:Published data on the association of vascular endothelial growth factor (VEGF) -1154G>A polymorphism with cancer risk is inconclusive. To derive a more precise estimation of association between VEGF -1154G>A polymorphism and the risk of cancer, we performed a meta-analysis of 7,071 cancer cases and 7,693 controls from...

journal_title：Molecular biology reports

authors： Hong TT,Zhang RX,Wu XH,Hua D

更新日期：2012-05-01 00:00:00

abstract：:The small molecules already existing on the earth can be assembled to biological macromolecules in the presence of the suitable tool. A workman must sharpen his tools if he is to do his work well. The tool must be specific, delicate and automatic. Obviously, it is enzyme. Therefore, to explore the origin of life we mu...

journal_title：Molecular biology reports

authors： Yin X,Yuan Z

更新日期：2009-02-01 00:00:00

abstract：:Recently, differentiated somatic cells had been reprogrammed to pluripotential state in vitro, and various tissue cells had been elicited from those cells. Epigenetic modifications allow differentiated cells to perpetuate the molecular memory needed for the cells to retain their identity. DNA methylation and histone d...

journal_title：Molecular biology reports

authors： Zhang XM,Li QM,Su DJ,Wang N,Shan ZY,Jin LH,Lei L

更新日期：2010-03-01 00:00:00

abstract：:Tomato bacterial wilt (BW) incited by Ralstonia solanacearum is a constraint on tomato production in tropical, subtropical and humid regions of the world. In this paper, we present the results of a research aimed at the identification of PCR-based markers amplified fragment length polymorphism (AFLP) linked to the gen...

journal_title：Molecular biology reports

authors： Miao L,Shou S,Cai J,Jiang F,Zhu Z,Li H

更新日期：2009-03-01 00:00:00

abstract：:Silky Fowl is a natural mutant with hyperpigmentation of various internal tissues. Although the mechanism of hyperpigmentation remains unclear, recent studies have shown that the abnormal migration of melanoblast and the absence of environmental barrier molecules are responsible for the hyperpigmentation in Silky Fowl...

journal_title：Molecular biology reports

authors： Li Y,Zhu X,Yang L,Li J,Lian Z,Li N,Deng X

更新日期：2011-02-01 00:00:00

abstract：:Movement assisted by muscles forms the basis of various behavioural traits seen in Drosophila. Myogenesis involves developmental processes like cellular specification, differentiation, migration, fusion, adherence to tendons and neuronal innervation in a series of coordinated event well defined in body space and time....

journal_title：Molecular biology reports

authors： Dubey M,Ain U,Firdaus H

更新日期：2020-12-01 00:00:00

abstract：:DNA-, RNA- and protein synthesis have been studied in Mycobacterium smegmatis cells infected with phage I3. The macromolecular synthesis continued until the end of latent period. Early RNA and protein synthesis were necessary prior to the commencement of DNA replication. The infecting phage DNA sedimented as larger th...

journal_title：Molecular biology reports

authors： Nagaraja V,Gopinathan KP

更新日期：1981-11-30 00:00:00