Proteasomes (prosomes) inhibit the translation of tobacco mosaic virus RNA by preventing the formation of initiation complexes.

abstract：:Published data on the association of vascular endothelial growth factor (VEGF) -1154G>A polymorphism with cancer risk is inconclusive. To derive a more precise estimation of association between VEGF -1154G>A polymorphism and the risk of cancer, we performed a meta-analysis of 7,071 cancer cases and 7,693 controls from...

journal_title：Molecular biology reports

authors： Hong TT,Zhang RX,Wu XH,Hua D

更新日期：2012-05-01 00:00:00

abstract：:Micro-RNAs (miRNAs) play key roles in regulating genes of the immune system. The aim of this study was to examine the expression of miR-1, 21 and 125a in the immune cells taken from the peripheral blood of patients suffering from chronic HBV infection (CHB). This cross-sectional study was performed on 60 CHB patients ...

journal_title：Molecular biology reports

authors： Momeni M,Hassanshahi G,Arababadi MK,Kennedy D

更新日期：2014-07-01 00:00:00

abstract：:As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, sc...

journal_title：Molecular biology reports

authors： Chen B,Pan W,Zhang L,Liu J,Ouyang H,Nie Q,Zhang X

更新日期：2014-10-01 00:00:00

abstract：:Syndecan-1 has been implicated in tumorigenesis and progression of various human malignancies. Recent studies have demonstrated that syndecan-1 may have a different function and biological activity depending on the specific tumor type. Therefore, the aim of this study was to investigate the clinical significance of sy...

journal_title：Molecular biology reports

authors： Xu Y,Yuan J,Zhang Z,Lin L,Xu S

更新日期：2012-09-01 00:00:00

abstract：:In plants, stomata play a pivotal role in the regulation of gas exchange and are distributed throughout the aerial epidermis. SDD1, a gene isolated from Arabidopsis thaliana has been demonstrated to specialize in stomatal density and distribution. In our present study, a comprehensive survey of global gene expression ...

journal_title：Molecular biology reports

authors： Xiao Y,Yu X,Chen J,Di P,Chen W,Zhang L

更新日期：2010-02-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies ha...

journal_title：Molecular biology reports

authors： Yue W,Fang X,Zhang C,Pang Y,Xu H,Gu C,Shao R,Lei C,Chen H

更新日期：2011-06-01 00:00:00

abstract：:Metabolic syndrome is an agglomeration of disorders including obesity, diabetes and cardiovascular diseases and characterized as chronic mild inflammation which elevates the circulatory inflammatory markers. This could be due to mitochondrial dysfunction, oxidative stress and hypoxia as a consequence of high fat diet ...

journal_title：Molecular biology reports

authors： Jha D,Mitra Mazumder P

更新日期：2019-04-01 00:00:00

abstract：:Various case-control studies have shown association of single nucleotide polymorphism rs12303764(G/T) in ULK1 with crohn's disease. The techniques used in these studies were time consuming, complicated and require sophisticated/expensive instruments. Therefore, in order to overcome these problems, we have developed a ...

journal_title：Molecular biology reports

authors： Randhawa R,Duseja A,Changotra H

更新日期：2017-02-01 00:00:00

abstract：:Stable inheritance and expression of transgene are important parameters for successful use of a transgenic crop. We previously transformed a Bt cry1Ba3 gene into cabbage inbred line CA21-3. To evaluate the stability of our Bt cabbage lineages, transgene inheritance and expression were examined in four successive gener...

journal_title：Molecular biology reports

authors： Yi DX,Fang ZY,Yang LM

更新日期：2020-04-01 00:00:00

abstract：:Differential display (DD) is a novel PCR-based technique, very commonly used to study differentially expressed genes at the mRNA level. In this paper we report a modified version of this technique that we have used to study the differences between the mRNA population from brain tissue of adult and old rats. We have mo...

journal_title：Molecular biology reports

authors： Pathak RU,Kanungo MS

更新日期：2007-03-01 00:00:00

abstract：:In this study, the effect of aucubin on H(2)O(2)-induced apoptosis was studied by using a rat pheochromocytoma (PC12) cell line. We have analyzed the apoptosis of H(2)O(2)-induced PC12 cells, H(2)O(2)-induced apoptosis appeared to correlate with lower Bcl-2 expression, higher Bax expression and sequential activation o...

journal_title：Molecular biology reports

authors： Xue HY,Niu DY,Gao GZ,Lin QY,Jin LJ,Xu YP

更新日期：2011-06-01 00:00:00

abstract：:The Italian National Reference Center for Echinococcosis (CeNRE, Sassari, Italy) set up a diagnostic protocol of "one-step-PCR" useful for the detection of E. granulosus sensu stricto (E.g.s.s.) and the identification of its genotype (G1-G3). The purpose of this work was to perform the validation of the "PCR E.g.s.s."...

journal_title：Molecular biology reports

authors： Santucciu C,Masu G,Mura A,Peruzzu A,Piseddu T,Bonelli P,Masala G

更新日期：2019-04-01 00:00:00

abstract：:Expressed sequence tags (ESTs) provide valuable tools that can be used to predict the genes involved in primary and secondary metabolite synthesis. To the best of our knowledge, ESTs have not yet been developed for Codonopsis. lanceolata, and therefore, the EST referenced in this report is the first transcript for C. ...

journal_title：Molecular biology reports

authors： Sathiyamoorthy S,In JG,Lee OR,Lee BS,Devi SR,Yang DC

更新日期：2011-06-01 00:00:00

abstract：:The human dopamine transporter gene (hDAT) encodes the dopamine transporter in dopamine (DA) neurons to regulate DA transmission. hDAT expression varies significantly from neuron to neuron, and from individual to individual so that dysregulation of hDAT is related to many neuropsychiatric disorders. It is critical to ...

journal_title：Molecular biology reports

authors： Zhao Y,Zhou Y,Xiong N,Lin Z

更新日期：2012-05-01 00:00:00

abstract：:Many case-control studies have investigated the role of TGF-β1 gene +869C/T promoter polymorphism in autoimmune diseases, but the results are inconsistent. To clarify this point, we performed a meta-analysis based on all available studies in Pubmed, Elsevier Science Direct, Google Searching, Chinese Biomedical Literat...

journal_title：Molecular biology reports

authors： Zhang L,Yan JW,Wang YX,Wan YN,Li JP,Liu P,Xu B,Wang BX,Peng WJ,Pan FM,Wang J

更新日期：2013-08-01 00:00:00

abstract：:Recently genetics and epigenetics alterations have been found to be characteristic of malignancy and hence can be used as targets for detection of neoplasia. RAS association domain family protein 1A (RASSF1A) gene hypermethylation has been a subject of interest in recent researches on cancer breast patients. The aim o...

journal_title：Molecular biology reports

authors： Hagrass HA,Pasha HF,Shaheen MA,Abdel Bary EH,Kassem R

更新日期：2014-01-01 00:00:00

abstract：:Bacterial leaf streak (BLS) caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an important disease of rice, which is responsible for the economic losses worldwide. Functional investigation of differentially expressed protein genes (DEPGs) from rice (Oryza sativa L.) upon Xoc infection provides insight into the molec...

journal_title：Molecular biology reports

authors： Guo L,Guo C,Li M,Wang W,Luo C,Zhang Y,Chen L

更新日期：2014-01-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:MAPK kinase 1 interacting protein 1 (MAP2K1ip1) is an important scaffold proteins of the mitogen-activated protein kinase (MAPK) pathway that form an active signaling module and enhance the specificity and spatiality of MAPK signaling. In the present study, we identified and characterized a MAP2K1ip1 cDNA from tiger s...

journal_title：Molecular biology reports

authors： Yang L,Liu X,Huang J,Yang Q,Qiu L,Liu W,Jiang S

更新日期：2012-05-01 00:00:00

abstract：:Apolipoprotein AV (apoAV) modulates plasma triglyceride levels, which is an independent risk factor for cardiovascular disease. ApoAV is also involved in atherosclerosis lesion formation. In order to systematically evaluate the apolipoprotein-related gene profile in tree shrew, a model for its insusceptibility to athe...

journal_title：Molecular biology reports

authors： Li G,Luo H,Sun G,Wu G,Wu G,Wang Y,Man Y,Wang S,Li J,Chen B

更新日期：2013-09-01 00:00:00

abstract：:In attempting to produce the HAP, endoplasmic reticulum (ER) targeted apoptosis-inducing protein, as a GST-fusion protein we found that the expression of HAP, but not GST alone, induced bacterial cell death. The HAP protein inhibited the bacterial growth within 30 min after inducting HAP expression. The transmission e...

journal_title：Molecular biology reports

authors： Gan M,Qi Y,Wan Q,Kuang E,Liu Q,Liu X

更新日期：2004-09-01 00:00:00

abstract：:The Giant Panda is an endangered and valuable gene pool in genetic, its important functional gene POLR2H encodes an essential shared peptide H of RNA polymerases. The genomic DNA and cDNA sequences were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) adopting touchdown-PCR and reve...

journal_title：Molecular biology reports

authors： Du YJ,Hou YL,Hou WR

更新日期：2013-02-01 00:00:00

abstract：:In the post-genomic era, providing a detailed description of protein functions poses a formidable challenge. To gain functional insights, we have to construct many kinds of expression vectors. DNA recombination based on polymerase chain reaction (PCR) and digestion followed by ligation is the preferred method for vect...

journal_title：Molecular biology reports

authors： Pan JS,Zhang ZP,Cai JY,Dong J,Ren JL,Wang XZ

更新日期：2010-03-01 00:00:00

abstract：:The Cdx-2 polymorphism in VDR gene has been extensively investigated for association with cancer risk, however, results of different studies have been inconsistent. The objective of this study is to assess the relationship of the Cdx-2 polymorphism in VDR and cancer risk by meta-analysis. All eligible case-control stu...

journal_title：Molecular biology reports

authors： Huang J,Huang J,Ma Y,Wang H,Yang J,Xiong T,Du L

更新日期：2013-07-01 00:00:00

abstract：:The objective of this study was to estimate the impact of the polymorphism of μ-calpain (CAPN1S) gene on protein changes of the cattle muscle tissue and its tenderness during 10-day cold storage. The analysis was performed on the longest dorsal and lumbar muscles collected from 76 bulls 6 to 12 months of age. Polymorp...

journal_title：Molecular biology reports

authors： Iwanowska A,Grześ B,Mikołajczak B,Iwańska E,Juszczuk-Kubiak E,Rosochacki SJ,Pospiech E

更新日期：2011-02-01 00:00:00

abstract：:Porcine MYOD1 gene has been mapped to swine chromosome (SSC) 2p14-p17, which is involved in the regulation of the proliferation and differentiation of skeletal muscle cells. The LDHA (lactate dehydrogenase A) and COPB1 (coatomer protein complex, subunit beta 1) genes, which map close to MYOD1, are involved in energy m...

journal_title：Molecular biology reports

authors： Qiu H,Xu X,Fan B,Rothschild MF,Martin Y,Liu B

更新日期：2010-01-01 00:00:00

abstract：:Penicillin V is a bacteriolytic β-lactam antibiotic drug. In the present work, we investigated the inhibitory effect of Penicillin V on the activity of mushroom tyrosinase for the first time. The molecular mechanism for the inhibition of tyrosinase by Penicillin V was investigated by means of kinetics analysis, fluore...

journal_title：Molecular biology reports

authors： Dong X,Wang S,Xu L,Lin J,Xu X

更新日期：2020-02-01 00:00:00

abstract：:Tall fescue is a perennial cool-season grass with economic importance especially in temperate regions of the northern hemisphere. This study was done to assess the genetic diversity and population structure of 90 tall fescue populations and cultivars using ISSR and EST-SSR markers in order to categorize valuable popul...

journal_title：Molecular biology reports

authors： Shahabzadeh Z,Mohammadi R,Darvishzadeh R,Jaffari M

更新日期：2020-01-01 00:00:00

abstract：:When chromosomal proteins in chromatin or in mononucleosomes were extensively cross-linked with an imido ester, the H1-containing nonameric histone complex was revealed. In this complex, histone H1 is connected with the octamer of core histones. The cross-linking of H1 of the octamer is realized preferentially through...

journal_title：Molecular biology reports

authors： Bakayev VV,Bakayeva TG,Domansky NN

更新日期：1981-08-14 00:00:00