Mammalian apoptosis-inducing protein, HAP, induces bacterial cell death.

abstract：:The phenylalanine and the phenylalanyl-tRNAPhe binding sites on the subunits of phenylalanyl-tRNA synthetase from E. coli MRE-600 were localized using p-azidoanilidate of [14C]phenylalanine and N-bromoacetyl-[14C]phenylalanyl-tRNAPhe. The phenylalanine recognizing site was shown to be situated on the alpha subunit of ...

journal_title：Molecular biology reports

authors： Lavrik OI,Moor NA,Khodyreva SN

更新日期：1982-03-31 00:00:00

abstract：:Nijmegen Breakage Syndrome protein 1 (NBS1) is one of the most important DNA repair proteins playing important roles in maintaining the genomic stability of NDA. Previous studies regarding the association between NBS1 8360G>C (Glu185Gln) polymorphism and lung cancer reported conflicting results. To derive a more preci...

journal_title：Molecular biology reports

authors： Wang L,Cheng J,Gao J,Wang J,Liu X,Xiong L

更新日期：2013-03-01 00:00:00

abstract：:Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indic...

journal_title：Molecular biology reports

authors： Hayashida K,Kohno S

更新日期：2009-07-01 00:00:00

abstract：:TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin processing recently, enzymes encoded by PCSK1 and PCSK2 are reported to play an important role in the process of proinsulin conversion. To investigate whether the single nucleotide polymorphisms...

journal_title：Molecular biology reports

authors： Zheng X,Ren W,Zhang S,Liu J,Li S,Li J,Yang P,He J,Su S,Li P

更新日期：2012-01-01 00:00:00

abstract：:CENP-A locates at nucleosome as histone H3-like proteins, and is phosphorylated during mitosis. We investigated the dynamic distribution of p-CENP-A to explore the details of its function. We found that p-CENP-A was phosphorylated at late prophase, and the signal of p-CENP-A arranged at equatorial plate along with nuc...

journal_title：Molecular biology reports

authors： Li D,Liu R,Song L,Zhou H,Chen J,Huang X

更新日期：2008-12-01 00:00:00

abstract：:We investigated phenotypic variations for pod shattering, pod length and number of seeds per pod in large germplasm collections of Brassica juncea (2n = 36; AABB) and its progenitor species, B. rapa (2n = 20; AA) and B. nigra (2n = 16; BB). Pod shatter resistance was measured as energy required for rupturing a mature ...

journal_title：Molecular biology reports

authors： Kaur J,Akhatar J,Goyal A,Kaur N,Kaur S,Mittal M,Kumar N,Sharma H,Banga S,Banga SS

更新日期：2020-04-01 00:00:00

abstract：:It is well-established that an impaired adipose tissue function and morphology caused by a dysregulated gene expression contribute substantially to obesity. Nowadays, animal model studies and in vitro surveys provide evidence for possible roles of HDACs as emerging epigenetic players in the pathogenesis of obesity. Ho...

journal_title：Molecular biology reports

authors： Jannat Ali Pour N,Meshkani R,Toolabi K,Mohassel Azadi S,Zand S,Emamgholipour S

更新日期：2020-05-01 00:00:00

abstract：:Brucella cell surface protein (BCSP31) is potentially useful for diagnosing brucellosis. We aimed to establish a monoclonal antibody (MAb) against Brucella melitensis BCSP31 and to investigate its distribution in diagnosis. Soluble recombinant BCSP31 was successfully expressed and purified. Two MAbs (1F1 and 1E5) agai...

journal_title：Molecular biology reports

authors： Zhang L,Wu XA,Zhang FL,An CH,Sun YX,Bai WT,Xu ZK

更新日期：2012-01-01 00:00:00

abstract：:1-Deoxynojirimycin (DNJ), the main alkaloid in mulberry leaves, was recognized to treat patients with type 2 diabetes mellitus (T2DM). However, the regulatory mechanism of DNJ on glucose homeostasis was still unclear. In the present study, a safe concentration of 0.1-10 μmol/L for DNJ was incubated with mature 3T3-L1 ...

journal_title：Molecular biology reports

authors： Li Q,Wang Y,Dai Y,Shen W,Liao S,Zou Y

更新日期：2019-12-01 00:00:00

abstract：:Adequate metabolic adaptation of key tissues playing an essential role for bioenergetic homeostasis and lactogenesis is critical in cows to adapt to changes in energy requirements and physiological processes during the lactation period. Mitochondria are recognized as central to meet energy needs and maintaining of met...

journal_title：Molecular biology reports

authors： Weikard R,Kuehn C

更新日期：2018-10-01 00:00:00

abstract：:The genes of E. coli are located on a circular chromosome of 4.6 million basepairs. This 1.6 mm long molecule is compressed into a nucleoid to fit inside the 1-2 microm cell in a functional format. To examine the role of DNA supercoiling as nucleoid compaction force we modulated the activity of DNA gyrase by electroni...

journal_title：Molecular biology reports

authors： Stuger R,Woldringh CL,van der Weijden CC,Vischer NO,Bakker BM,van Spanning RJ,Snoep JL,Westerhoff HV

更新日期：2002-01-01 00:00:00

abstract：:Molecular DNA markers are used for detection of polymorphisms in individuals. As they are independent of developmental stage of the plant and environmental influences, they can be useful tools in taxonomy. The alleles of simple sequence repeat (SSR) markers (or microsatellites) are traditionally used to identify taxon...

journal_title：Molecular biology reports

authors： Tuler AC,Carrijo TT,Nóia LR,Ferreira A,Peixoto AL,da Silva Ferreira MF

更新日期：2015-11-01 00:00:00

abstract：:The mechanism by which external Bax releases cytochrome c is still controversial and may also depend on the type of mitochondria and the actual localisation of cytochrome c. Outer membrane porin acquires high binding affinity for hexokinase by interacting with the adenine nucleotide translocator (ANT) in the contact s...

journal_title：Molecular biology reports

authors： Vyssokikh MY,Zorova L,Zorov D,Heimlich G,Jürgensmeier JJ,Brdiczka D

更新日期：2002-01-01 00:00:00

abstract：:Familial Mediterranean fever is an autosomal recessive disorder characterized by recurrent attacks of abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible for the disease. The objective of this study was to identify the frequency and distribution of 12 MEFV mutations in 153 Syrian patients and ...

journal_title：Molecular biology reports

authors： Jarjour RA

更新日期：2010-01-01 00:00:00

abstract：:The response of the respiratory subsystem of oxidative phosphorylation to the environmental pollutant, 2,2',5,5'-tetrachlorobiphenyl (2,2',5,5'-TCB) was investigated by modular kinetic approach. The effects of 20 microM 2,2',5,5'-TCB on the activity of the respiratory chain modules in rat liver mitochondria oxidizing ...

journal_title：Molecular biology reports

authors： Mildaziene V,Nauciene Z,Krab K

更新日期：2002-01-01 00:00:00

abstract：:Large-scale random cDNA sequencing projects have been started for several organisms and are a valuable tool for the analysis of quantitative and qualitative aspects of gene expression. However, the reliability of the obtained data is limited as most of the clones are only partially analysed on one strand. As a consequ...

journal_title：Molecular biology reports

authors： Braun HP

更新日期：1996-01-01 00:00:00

abstract：:STAT4 is a transcription factor that has been implicated in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Recently, several reports has documented that a STAT4 haplotype is associated with RA, SLE and Sjogren's syndrome. To summarize and review these findings, we conducted a met...

journal_title：Molecular biology reports

authors： Ji JD,Lee WJ,Kong KA,Woo JH,Choi SJ,Lee YH,Song GG

更新日期：2010-01-01 00:00:00

abstract：:Overexpression of domains of a human protein using recombinant DNA technology has been challenging because individual domains intend to accumulate as non-soluble aggregate when expressed separately. Studies on identifying right sequences for a domain to be able to fold independently may help understand the folding pat...

journal_title：Molecular biology reports

authors： Tiwary M,Agarwal N,Dinda A,Yadav SC

更新日期：2016-05-01 00:00:00

abstract：:Apolipoprotein AV (apoAV) modulates plasma triglyceride levels, which is an independent risk factor for cardiovascular disease. ApoAV is also involved in atherosclerosis lesion formation. In order to systematically evaluate the apolipoprotein-related gene profile in tree shrew, a model for its insusceptibility to athe...

journal_title：Molecular biology reports

authors： Li G,Luo H,Sun G,Wu G,Wu G,Wang Y,Man Y,Wang S,Li J,Chen B

更新日期：2013-09-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a world-wide health problem and its incidence accounts for 1.9-3.5% of all malignant tumors. Transforming growth factor beta/Smads (TGF-beta/Smads) signaling pathway plays an important role in oncogenesis, but its function and molecular mechanisms in OSCC remain unclear. Expressi...

journal_title：Molecular biology reports

authors： Wang X,Sun W,Bai J,Ma L,Yu Y,Geng J,Qi J,Shi Z,Fu S

更新日期：2009-05-01 00:00:00

abstract：:Many studies have been performed to identify regulatory circuit underlying plant stress tolerance. However, the reliability of some findings has been criticized because of exclusive use of stress sensitive plant species such as Arabidopsis thaliana. Sensitive plant species often harbor narrow defensive mechanisms and ...

journal_title：Molecular biology reports

authors： Shamloo-Dashtpagerdi R,Razi H,Ebrahimie E,Niazi A

更新日期：2018-10-01 00:00:00

abstract：:Northeast of China is the main soybean production area, drought and low-temperature tolerance are both main factors involved in reducing soybean yield and limiting planting regions, the most effective way to solve this problem is to breed cultivars with drought and low-temperature tolerance. A set of the BC(2)F(3) lin...

journal_title：Molecular biology reports

authors： Zhang WB,Qiu PC,Jiang HW,Liu CY,Xin da W,Li CD,Hu GH,Chen QS

更新日期：2012-05-01 00:00:00

abstract：:The occurrence of PFD is closely related with elasticity, toughness, and functional changes of the connective tissue of the pelvic support tissue. This study aims to evaluate the effect of mechanical stretch on the differentiation of BMSCs with a co-culture with pelvic ligament fibroblasts. BMSCs was isolated and iden...

journal_title：Molecular biology reports

authors： Bing Z,Linlin L,Jianguo Y,Shenshen R,Ruifang R,Xi Z

更新日期：2012-05-01 00:00:00

abstract：:Two calcium carbonate crystal polymorphs, aragonite and calcite, are the main inorganic components of mollusk shells. Some fossil evidences suggest that aragonite shell is more ancient than calcite shell for the Bivalvia. But, the molecular biology evidence for the above deduction is absent. In this study, we searched...

journal_title：Molecular biology reports

authors： Wang X,Li L,Zhu Y,Song X,Fang X,Huang R,Que H,Zhang G

更新日期：2014-11-01 00:00:00

abstract：:Patients with β-thalassemia suffer from a lack or absence of the beta-globin chain of normal hemoglobin (Hb). Therefore, an increase in fetal Hb (HbF) levels could improve the clinical status of these patients. Downregulation of BCL11A, a key regulatory transcription factor, could ameliorate the clinical status of tha...

journal_title：Molecular biology reports

authors： Gholampour MA,Asadi M,Naderi M,Azarkeivan A,Soleimani M,Atashi A

更新日期：2020-05-01 00:00:00

abstract：:Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there is no study investigating the role of the genes in paranasal sinus carcinomas. The aim of the study was to assess the role of the PI3K/AKT/mTOR ...

journal_title：Molecular biology reports

authors： Biray Avci C,Sezgin B,Goker Bagca B,Karci HB,Gode S

更新日期：2020-05-01 00:00:00

abstract：:Tomato bacterial wilt (BW) incited by Ralstonia solanacearum is a constraint on tomato production in tropical, subtropical and humid regions of the world. In this paper, we present the results of a research aimed at the identification of PCR-based markers amplified fragment length polymorphism (AFLP) linked to the gen...

journal_title：Molecular biology reports

authors： Miao L,Shou S,Cai J,Jiang F,Zhu Z,Li H

更新日期：2009-03-01 00:00:00

abstract：:Telomeres have lately received considerable attention in the development of tree species. Normal somatic cells have limited replicative capacity and telomeres get shorten with each round of DNA replication. For broad-leaved tree species, to determine what changes happen to their somatic cells in its annual development...

journal_title：Molecular biology reports

authors： Song H,Liu D,Chen X,Ying Z,Zhang B,Li F,Lu H

更新日期：2010-02-01 00:00:00

abstract：:In plants, stomata play a pivotal role in the regulation of gas exchange and are distributed throughout the aerial epidermis. SDD1, a gene isolated from Arabidopsis thaliana has been demonstrated to specialize in stomatal density and distribution. In our present study, a comprehensive survey of global gene expression ...

journal_title：Molecular biology reports

authors： Xiao Y,Yu X,Chen J,Di P,Chen W,Zhang L

更新日期：2010-02-01 00:00:00

abstract：:We report here cloning and characterization of a novel human gene, termed VMP, which is a vesicular membrane protein. RT-PCR analysis shows that VMP is expressed exclusively in brain of the 16 tissues examined, suggesting that it is a neuron-specific membrane protein. The cDNA encodes 195 amino acid with a putative mo...

journal_title：Molecular biology reports

authors： Cheng C,Xu J,Ye X,Dai J,Wu Q,Zeng L,Wang L,Zhao W,Ji C,Gu S,Xie Y,Mao Y

更新日期：2002-09-01 00:00:00