Molecular characterization and expression profile of MAP2K1ip1/MP1 gene from tiger shrimp, Penaeus monodon.

abstract：:The objective of this study was to determine hepatic expression levels of GHR, IGF1R, IGF1 and IGF2 genes in young growing gilts at different developmental ages (60-210 days) in five pig breeds: Polish Large White (PLW), Polish Landrace (PL), Pulawska (Pul), Duroc (Dur) and Pietrain (Pie). We studied the differences a...

journal_title：Molecular biology reports

authors： Pierzchała M,Pareek CS,Urbański P,Goluch D,Kamyczek M,Różycki M,Smoczynski R,Horbańczuk JO,Kurył J

更新日期：2012-03-01 00:00:00

abstract：:Cardiomyocytes possess the ability to respond to mechanical stimuli by reprogramming their gene expression. This study investigated the effects of different loading protocols on signaling and expression responses of myogenic, anabolic, inflammatory, atrophy and pro-apoptotic genes in cardiomyocyte-like H9C2 cells. Dif...

journal_title：Molecular biology reports

authors： Zevolis E,Philippou A,Moustogiannis A,Chatzigeorgiou A,Koutsilieris M

更新日期：2021-01-04 00:00:00

abstract：:Interferon gamma (IFN-γ) is an important immunoregulatory cytokine that has a central role against viral and bacterial infections. In this study, the cDNA encoding 141 amino acids of mature IFN-γ from mice splenocytes was cloned in a prokaryotic expression vector pQE 30. Optimization of expression conditions resulted ...

journal_title：Molecular biology reports

authors： Kumar M,Singh M,Singh SB

更新日期：2014-10-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:A cDNA encoding an O-methyltransferase (namely FGCOMT1) was identified from the medicinal plant Trigonella foenum-graecum L. The FGCOMT1 enzyme is a functional caffeic acid O-methyltransferase (COMT) and is localized in the cytosol. Kinetic analysis indicated that FGCOMT1 protein exhibited the highest catalyzing effic...

journal_title：Molecular biology reports

authors： Qin JC,Zhang YM,Lang CY,Yao YH,Pan HY,Li X

更新日期：2012-02-01 00:00:00

abstract：:Micro-RNAs (miRNAs) play key roles in regulating genes of the immune system. The aim of this study was to examine the expression of miR-1, 21 and 125a in the immune cells taken from the peripheral blood of patients suffering from chronic HBV infection (CHB). This cross-sectional study was performed on 60 CHB patients ...

journal_title：Molecular biology reports

authors： Momeni M,Hassanshahi G,Arababadi MK,Kennedy D

更新日期：2014-07-01 00:00:00

abstract：:According to the stem cell theory for cancer, hepatocellular carcinomas are sustained by a group of cancer stem cells (CSCs) which are responsible for resistance to chemotherapy. In the present study we aimed to examine lipid metabolism in cancer stem cells induced by long-term treatment with sorafenib and its relatio...

journal_title：Molecular biology reports

authors： Bort A,Sánchez BG,de Miguel I,Mateos-Gómez PA,Diaz-Laviada I

更新日期：2020-04-01 00:00:00

abstract：:Two genes HPC/ELAC-2 and AAT were studied in north Indian population. HPC/ELAC-2 was studied in prostate cancer cases and AAT was studied in COPD patients. HPC/ELAC-2 is considered as an important cancer-susceptibility gene in prostate cancer. There are two common polymorphisms of this gene, i.e., Ser217Leu and Ala541...

journal_title：Molecular biology reports

authors： Sobti RC,Thakur H,Gupta L,Janmeja AK,Seth A,Singh SK

更新日期：2011-06-01 00:00:00

abstract：:In spite of much awareness, diabetes mellitus continues to remain one of major reasons for mortality and morbidity rate all over the globe. Free radicals cause oxidative stress which is responsible for causing diabetes. The recent advancements in elucidation of ARE/keap1/Nrf2 pathway can help in better understanding o...

journal_title：Molecular biology reports

authors： Behl T,Kaur I,Sehgal A,Sharma E,Kumar A,Grover M,Bungau S

更新日期：2021-01-03 00:00:00

abstract：:The blue swimming crab (Portunus pelagicus) is a valuable marine fishery resource in Indo-West Pacific Ocean. So far, rare genetic resource of this species is available. In this report, the restriction-site associated DNA (RAD) approach was employed to mine the genomic information and identify molecular markers in P. ...

journal_title：Molecular biology reports

authors： Wu Q,Miao G,Li X,Liu W,Ikhwanuddin M,Ma H

更新日期：2018-12-01 00:00:00

abstract：:The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice. The tumor xenograft models were established and randomly assigned to 4 groups: control group, Endostar group (1.5 mg/kg day, once daily for 3 weeks), chemotherap...

journal_title：Molecular biology reports

authors： Chang L,Guo F,Lv Y,Wang Y,Huo B,Wang L,Liu W

更新日期：2013-01-01 00:00:00

abstract：:Schizophrenia is a chronic and neuropsychiatric disease that affects about 0.5-1% of the world's population. An increase in dopamine and dopamine D2 receptor (DRD2) gene products has been well described in schizophrenic patients. Several groups have studied the relationship between dopaminergic hyperactivity and cellu...

journal_title：Molecular biology reports

authors： Kurt H,Dikmen M,Basaran A,Yenilmez C,Ozdemir F,Degirmenci I,Gunes HV,Kucuk MU,Mutlu F

更新日期：2011-02-01 00:00:00

abstract：:Cytokinin oxidases are involved in the regulation of plant cytokinin levels, which are important in regulating plant growth and development, and may affect the yield of cereals. Here, we report the isolation and characterization of two putative cytokinin oxidase genes, TaCKX2.1 and TaCKX2.2, from wheat. Both TaCKX2.1 ...

journal_title：Molecular biology reports

authors： Zhang J,Liu W,Yang X,Gao A,Li X,Wu X,Li L

更新日期：2011-04-01 00:00:00

abstract：:Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...

journal_title：Molecular biology reports

authors： Vasconcelos GM,Gonçalves BA,Montalvão-de-Azevedo R,Thuler LC,Braga FH,Pombo-de-Oliveira MS,de Camargo B,Brazilian Embryonal Tumor Group.

更新日期：2014-09-01 00:00:00

abstract：:Type 2 diabetes is one of the most prevalent diseases, which increases resistance to insulin in target tissues. The measurement of miRNAs quantity is a molecular approach for diagnosis of diabetes. miRNAs are small non-coding RNA strings of 21-23 long nucleotides that act as inhibitors in proteins translation. Several...

journal_title：Molecular biology reports

authors： Andoorfar S,Hosseini Tafreshi SA,Rezvani Z

更新日期：2019-10-01 00:00:00

abstract：:ColE1 DNA replication is initiated by RNA II and inhibited by RNA I. Control of the replication occurs through the interaction between RNA I and RNA II. Therefore, RNases involved in the metabolism of RNA I and RNA II are expected to play a key role in the control of the ColE1 plasmid replication. RNase H, RNase E, RN...

journal_title：Molecular biology reports

authors： Jung YH,Lee Y

更新日期：1995-01-01 00:00:00

abstract：:The aim of this study was to describe the microbial communities in the distal gut of wild wolves (Canis lupus). Fecal samples were collected from three healthy unrelated adult wolves captured at the nearby of Dalai Lake Nature Reserve in Inner Mongolia of China. The diversity of fecal bacteria was investigated by cons...

journal_title：Molecular biology reports

authors： Zhang H,Chen L

更新日期：2010-12-01 00:00:00

abstract：:Melanotransferrin (MTf), a member of the transferrin families, plays an important role in immune response. But the research about MTf in sea cucumber is limited till now. In this study, the Melanotransferrin (Aj-MTf) gene was firstly cloned and characterized from the sea cucumber Apostichoupus japonicus by reverse tra...

journal_title：Molecular biology reports

authors： Qiu X,Li D,Cui J,Liu Y,Wang X

更新日期：2014-06-01 00:00:00

abstract：:The binding of a cell nucleus stain, hematoxylin (HTL), to bovine serum albumin (BSA) was studied by spectroscopy including fluorescence spectra, UV-Visible absorption, circular dichroism (CD) spectra, synchronous and three-dimensional fluorescence spectra. The results indicated that the binding had led to static fluo...

journal_title：Molecular biology reports

authors： Zhang HX,Gao S,Xiong ZY,Liu SP

更新日期：2009-11-01 00:00:00

abstract：:To investigate the effect of ketamine administration on memory consolidation, p-CREB and c-fos expression in hippocampus of infant rats and the possible mechanism. Ninety-six SD rats of 21 days old were divided into seven groups, Y-maze was used to test the ability of learning and memory for minor rats. p-CREB and c-f...

journal_title：Molecular biology reports

authors： Peng S,Zhang Y,Ren B,Zhang J,Wang H

更新日期：2011-04-01 00:00:00

abstract：:Toll-like receptors (TLRs) constitute a multi-gene family, which plays a pivotal role in sensing invading pathogens by virtue of conserved microbial patterns. TLR repertoire of chicken and zebra finch has been well studied. However TLR family of other avian species is yet to be characterized. In the present study, we ...

journal_title：Molecular biology reports

authors： Ramasamy KT,Reddy MR,Verma PC,Murugesan S

更新日期：2012-08-01 00:00:00

abstract：:The objective of this study was to estimate the impact of the polymorphism of μ-calpain (CAPN1S) gene on protein changes of the cattle muscle tissue and its tenderness during 10-day cold storage. The analysis was performed on the longest dorsal and lumbar muscles collected from 76 bulls 6 to 12 months of age. Polymorp...

journal_title：Molecular biology reports

authors： Iwanowska A,Grześ B,Mikołajczak B,Iwańska E,Juszczuk-Kubiak E,Rosochacki SJ,Pospiech E

更新日期：2011-02-01 00:00:00

abstract：:HSG1 (Heat shock-induced gene 1) is one of the high-temperature-induced proteins in grapevine. Sequence analysis has demonstrated that HSG1 is a grape Bcl-2-associated athanogene (BAG) that contains IQ and BAG domains in its sequence. HSG1 expression was not detected in leaves without heat treatment, while tendrils, s...

journal_title：Molecular biology reports

authors： Kobayashi M,Takato H,Fujita K,Suzuki S

更新日期：2012-04-01 00:00:00

abstract：:MicroRNAs (miRNAs) may play important roles in SLE, but genetic polymorphisms of miRNAs and their relationships with various autoantibodies present in SLE patients remain unclear. Here, we report that 213 SLE patients and 209 healthy individuals of Chinese had been taken into this case-control studies, which had been ...

journal_title：Molecular biology reports

authors： Zhang J,Yang B,Ying B,Li D,Shi Y,Song X,Cai B,Huang Z,Wu Y,Wang L

更新日期：2011-03-01 00:00:00

abstract：:Fascin homologue 1 (FSCN1) has established roles in cell adhesion, motility, and cell-cell interactions. Our LongSAGE analysis suggested that FSCN1 was potentially differentially expressed in prenatal pig skeletal muscle. We have cloned the genomic DNA and mRNA sequence of FSCN1 gene and mapped it to SSC3p16-p17. The ...

journal_title：Molecular biology reports

authors： Tang ZhL,Zhang XJ,Yang ShL,Mu YL,Cui WT,Ao H,Li K

更新日期：2010-06-01 00:00:00

abstract：:P73 is a structural and functional homologue of p53, and plays an important role in regulating cell cycle and apoptosis. A potentially functional polymorphism (designated as p73 G4C14-to-A4T14) has been identified in a region in exon 2 of the p73 gene, which may theoretically form a stem-loop structure and thereby aff...

journal_title：Molecular biology reports

authors： Wang L,Gao R,Yu L

更新日期：2012-02-01 00:00:00

abstract：:Inhibitor of growth protein 3 (ING3), a new member of ING family, is involved in the regulation of various processes. In this study, a full-length cDNA of ING3 (named as RpING3) was cloned from the gill of Ruditapes philippinarum by rapid amplification of cDNA ends method for the first time. The cDNA obtained was 1442...

journal_title：Molecular biology reports

authors： Hu GW,Yan XW,Qin YJ,Nie HT

更新日期：2014-06-01 00:00:00

abstract：:Nerve growth factor (NGF) is required for the differentiation and maintenance of sympathetic and sensory neurons. In the present study, the recombinant expression of human nerve growth factor beta (hNGF-β) gene in rabbit bone marrow mesenchymal stem cells (rMSCs) was undertaken. Recombinant vector containing hNGF-β wa...

journal_title：Molecular biology reports

authors： Fan BS,Lou JY

更新日期：2010-12-01 00:00:00

abstract：:In genome engineering, sgRNAs define the genomic target to be modified in CRISPR/Cas9 system. Either for single gene editing or genome-wide screens, sgRNAs are cloned into plasmid vectors. During our performance of CRISPR/Cas9 gene knock out, we found that the central part of a sgRNA was inverted after transformation ...

journal_title：Molecular biology reports

authors： Wang G,Sukumar S

更新日期：2020-08-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) has been investigated extensively at the molecular level. Nevertheless, genome wide study on the temporal and spatial dynamics of the virus is non-existed. To explore this topic, we determined complete coding genome sequences for four PRRSV isolates and analy...

journal_title：Molecular biology reports

authors： Yoon SH,Kim H,Kim J,Lee HK,Park B,Kim H

更新日期：2013-10-12 00:00:00