Methylation status and protein expression of RASSF1A in breast cancer patients.

abstract：:Deprivation of cytokines induces cell cycle arrest and apoptosis in cytokine-dependent hematopoietic progenitors. Previous studies have indicated that in Baf-3, interleukin (IL)-3-dependent cells, apoptosis is caused predominantly by Bim, a BH3-only cell death activator that belongs to the Bcl-2 superfamily. Because B...

journal_title：Molecular biology reports

authors： Matsui H,Shinjyo T,Inaba T

更新日期：2005-06-01 00:00:00

abstract：:The purpose of this study is to investigate the effect of H2O2 on the aging of melanogenesis in human melanocytes. The staining of SA-β-galactosidase, an aging marker, was remarkably increased in the cells aged with H2O2 at 62.5 µM or more compared with young cells. The intracellular H2O2 level and melanin synthesis w...

journal_title：Molecular biology reports

authors： Ko H,Kim MM

更新日期：2019-04-01 00:00:00

abstract：:The complete coding sequences of three porcine genes-SDHB, SNRPA and CRYBB1 were amplified using the reverse transcriptase polymerase chain reaction (RT-PCR) based on the conserved coding sequence information of the mouse or other mammals and highly homologous pig ESTs. These three genes were then deposited into GenBa...

journal_title：Molecular biology reports

authors： An QC,Liu GY

更新日期：2009-04-01 00:00:00

abstract：:The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...

journal_title：Molecular biology reports

authors： Mastrangelo S,Sardina MT,Riggio V,Portolano B

更新日期：2012-01-01 00:00:00

abstract：:Interindividual variability exists in statin lipid-lowering response, partially attributed to genetic factors. Organic anion-transporting polypeptide 1B1 (OATP1B1) encoded by SLCO1B1 gene (solute carrier organic anion transporter family member 1B1) facilitates hepatic uptake of simvastatin and atorvastatin. SLCO1B1 po...

journal_title：Molecular biology reports

authors： Giannakopoulou E,Ragia G,Kolovou V,Tavridou A,Tselepis AD,Elisaf M,Kolovou G,Manolopoulos VG

更新日期：2014-07-01 00:00:00

abstract：:Bone abnormalities as a consequence of osteoblast deregulation are associated with several diseases such as diabetes and chronic kidney disease. Important role for oxidized low density lipoproteins (oxLDL) in the pathophysiology of bone disorders has been reported. However, little is known about the effects and mechan...

journal_title：Molecular biology reports

authors： Dawodu D,Patecki M,Dumler I,Haller H,Kiyan Y

更新日期：2019-06-01 00:00:00

abstract：:When chromosomal proteins in chromatin or in mononucleosomes were extensively cross-linked with an imido ester, the H1-containing nonameric histone complex was revealed. In this complex, histone H1 is connected with the octamer of core histones. The cross-linking of H1 of the octamer is realized preferentially through...

journal_title：Molecular biology reports

authors： Bakayev VV,Bakayeva TG,Domansky NN

更新日期：1981-08-14 00:00:00

abstract：:Rhodoleia Champion ex Hooker is one of the most primitive relict genera of Hamamelidaceae, a key family exploited to understand the origin and early evolution of flowering plants. Genomic simple sequence repeats (SSRs) were developed for R. championii to perform genetic diversity, phylogeographical structure or even s...

journal_title：Molecular biology reports

authors： Huang Y,Yin Q,Do VT,Meng K,Chen S,Liao B,Fan Q

更新日期：2019-12-01 00:00:00

abstract：:The freshwater true bug Aphelocheirus aestivalis (Aphelocheiridae) is widely distributed in Europe but occurs rather locally and often in isolated populations. Moreover, it is threatened with extinction in parts of its range. Unfortunately, little is known about the genetic diversity and population structure due to th...

journal_title：Molecular biology reports

authors： Kaczmarczyk-Ziemba A

更新日期：2020-12-01 00:00:00

abstract：:Expressed sequence tags (ESTs) provide valuable tools that can be used to predict the genes involved in primary and secondary metabolite synthesis. To the best of our knowledge, ESTs have not yet been developed for Codonopsis. lanceolata, and therefore, the EST referenced in this report is the first transcript for C. ...

journal_title：Molecular biology reports

authors： Sathiyamoorthy S,In JG,Lee OR,Lee BS,Devi SR,Yang DC

更新日期：2011-06-01 00:00:00

abstract：:A copper(II) complex containing aspartame (APM) as ligand, Cu(APM)2Cl2·2H2O, was synthesized and characterized. In vitro binding interaction of this complex with human serum albumin (HSA) was studied at physiological pH. Binding studies of this complex with HSA are useful for understanding the Cu(APM)2Cl2·2H2O-HSA int...

journal_title：Molecular biology reports

authors： Shahabadi N,Khodaei MM,Kashanian S,Kheirdoosh F,Filli SM

更新日期：2014-05-01 00:00:00

abstract：:Our previous studies have shown that miR-125b-5p was highly expressed and significantly upregulated during abdominal fat deposition in chickens. However, the role of miR-125b in the regulation of adipogenesis is not clear in chickens. Therefore, we evaluated the effects of miR-125b-5p on preadipocyte proliferation and...

journal_title：Molecular biology reports

authors： Li G,Chen Y,Jin W,Zhai B,Li Y,Sun G,Li H,Kang X,Tian Y

更新日期：2021-01-04 00:00:00

abstract：:MAPK cascade is an important intracellular signaling module and function as a convergent point for crosstalk during abiotic stress signaling. In this study SbMAPKK gene has been isolated from Salicornia brachiata, a highly salt tolerant plant growing in costal marshes of Gujarat, India. The SbMAPKK gene is 1,023 bp lo...

journal_title：Molecular biology reports

authors： Agarwal PK,Gupta K,Jha B

更新日期：2010-02-01 00:00:00

abstract：:Fluorescent quantum dots (QDs) have been widely applied in biological and biomedical areas, but relatively little is known about the interaction of QDs with some natural enzymes. Herein, the interactions between 3-mercaptopropionic acid-capped CdTe QDs (MPA-QDs) and papain were systematically investigated by UV-Vis ab...

journal_title：Molecular biology reports

authors： Xiao Q,Qiu H,Huang S,Huang C,Su W,Hu B,Liu Y

更新日期：2013-10-01 00:00:00

abstract：:This study aims to investigate the apoptotic and anti-angiogenic effect of Zoledronic acid on hormone-refractory prostate cancer cell lines. XTT cell proliferation assay used to assess cytotoxicity. Caspase 3/7 activity and DNA fragmentation were measured to verify apoptosis. Angiogenic cytokine profiles investigated ...

journal_title：Molecular biology reports

authors： Gokalp C

更新日期：2020-10-01 00:00:00

abstract：:Sperm-mediated gene transfer (SMGT) has been long heralded as a faster and cheaper alternative to more commonly used methods of producing transgenic animals. In this study, the capra semen ejaculates were pooled together and then incubated in vitro with DIG-labeled DNA. The binding and internalizing rates were observe...

journal_title：Molecular biology reports

authors： Zhao Y,Yu M,Wang L,Li Y,Fan J,Yang Q,Jin Y

更新日期：2012-03-01 00:00:00

abstract：:NADH:ubiquinone oxidoreductase (complex I ) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone coupled to proton translocation across the membrane. The cDNA sequence of Dunaliella salina mitochondrial NADH: ubiquinone oxidoreductase 19-kD subunit contains a 682-bp ORF en...

journal_title：Molecular biology reports

authors： Liu Y,Qiao DR,Zheng HB,Dai XL,Bai LH,Zeng J,Cao Y

更新日期：2008-09-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:Vitiligo is an acquired pigmentary disorder characterized by loss of epidermal melanocytes. A strong association at a single nucleotide polymorphism (SNP) rs11966200 within MHC region had been identified in a recent genome-wide association study of generalized vitiligo in Chinese Han population. This study aims to inv...

journal_title：Molecular biology reports

authors： Tang J,Liu JL,Zhang C,Hu DY,He SM,Zuo XB,Wang PG,Sun LD,Zhang XJ,Yang S

更新日期：2013-06-01 00:00:00

abstract：:Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a multifunctional compound, which catalyzes several essential reactions for the protection of cellular components from oxidative and free radical damage. Based on a number of in vitro and in vivo studies, various mechanisms are proposed...

journal_title：Molecular biology reports

authors： Azad GK,Tomar RS

更新日期：2014-08-01 00:00:00

abstract：:Kawasaki disease (KD) is a multi-systemic vasculitis which preferentially affects infants and children. A single nucleotide polymorphism (rs28493229) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) was identified to be associated with the increased risk of KD; however, in more recent studies associations have b...

journal_title：Molecular biology reports

authors： Lou J,Xu S,Zou L,Zhong R,Zhang T,Sun Y,Lu X,Liu L,Li C,Wang L,Xiong G,Wang W,Gong F,Wu J

更新日期：2012-12-01 00:00:00

abstract：:We studied the distribution of the D/D, I/D, and I/I genotypes of the angiotensin-converting enzyme (ACE) in a sample of healthy Lebanese individuals to assess their prevalence and compare them with other populations. ACE genotypes were determined using the Cardiovascular Disease (CVD) StripAssay, which is based on a ...

journal_title：Molecular biology reports

authors： Sabbagh AS,Otrock ZK,Mahfoud ZR,Zaatari GS,Mahfouz RA

更新日期：2007-03-01 00:00:00

abstract：:The transforming growth factor-β (TGF-β) signaling pathway is conserved across animals, and knowledge of its roles during the molt cycle in crustaceans is presently very limited. This study investigates the roles of the TGF-β receptor in molting-related muscle growth in Eriocheir sinensis. Using the RT-PCR and RACE te...

journal_title：Molecular biology reports

authors： Tian Z,Peng H,Deng W,Jiao C

更新日期：2020-01-01 00:00:00

abstract：:Infection with mycobacterium tuberculosis (MTB) can cause different outcomes in hosts with variant genetic backgrounds. Previously, we identified an intracellular pathogen resistance 1 (Ipr1) gene with the role of resistance of MTB infection in mice model. However, until now, its binding proteins have been little know...

journal_title：Molecular biology reports

authors： Cai L,Pan H,Trzciński K,Thompson CM,Wu Q,Kramnik I

更新日期：2010-12-01 00:00:00

abstract：:Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there is no study investigating the role of the genes in paranasal sinus carcinomas. The aim of the study was to assess the role of the PI3K/AKT/mTOR ...

journal_title：Molecular biology reports

authors： Biray Avci C,Sezgin B,Goker Bagca B,Karci HB,Gode S

更新日期：2020-05-01 00:00:00

abstract：:Abnormally protein aggregation and deposition are key pathological features of ALS, which may related with dysfunctional cellular autophagy. In the current study, we found that, compared with wtSOD1 cells, serum starvation treatment resulted in significant higher percentage of apoptosis in mutSOD1 cells; Lithium treat...

journal_title：Molecular biology reports

authors： Yin X,Wang S,Wang X,Yang Y,Jiang H,Wang T,Wang Y,Zhang C,Feng H

更新日期：2019-12-01 00:00:00

abstract：:Common bacterial blight (CBB), incited by Xanthomonas axonopodis pv. phaseoli (Xap), is a serious seed-borne disease of common bean (Phaseolus vulgaris L.) in both temperate and tropical production zones. The line HR45 is highly resistant to Xap infection on leaves and pods in both field and greenhouse. To understand ...

journal_title：Molecular biology reports

authors： Shi C,Chaudhary S,Yu K,Park SJ,Navabi A,McClean PE

更新日期：2011-01-01 00:00:00

abstract：:Genetics can provide invaluable tools for management and conservation of bee populations, which are declining worldwide. Among these tools, microsatellite are very useful molecular markers for population analyses. The aim of this study was to isolate and characterize microsatellites for Epicharis (Anepicharis) dejeani...

journal_title：Molecular biology reports

authors： Souza-Shibatta L,Ricardo PC,Pina WC,Flaresso-Neto V,Freiria GA,Kotelok-Diniz T,Gaglianone MC,Arias MC,Sofia SH

更新日期：2021-01-21 00:00:00

abstract：:The GRAS gene family is a family of transcription factors that regulates plant growth and development. Despite being well-studied in many plant species, little is known about this gene family in orchardgrass (Dactylis glomerata L.), one of the top four economically important perennial forage grasses cultivated worldwi...

journal_title：Molecular biology reports

authors： Xu X,Feng G,Huang L,Yang Z,Liu Q,Shuai Y,Zhang X

更新日期：2020-03-01 00:00:00

abstract：:This experiment was conducted to explore the biological functions of myogenin (MyoG) gene. MyoG gene was cloned from genome of Hu sheep by overlap extension PCR. Then, pEGFP-C1-MyoG and pcDNA3.0-MyoG fusion expression vectors was constructed and pEGFP-C1-MyoG vector had been transfected into NIH-3T3 cells by liposomes...

journal_title：Molecular biology reports

authors： Zhang Z,Xu F,Zhang Y,Li W,Yin Y,Zhu C,Du L,Elsayed AK,Li B

更新日期：2014-02-01 00:00:00