Rapid development of 56 novel microsatellite markers for the benthic freshwater bug Aphelocheirus aestivalis using Illumina paired-end sequencing data and M13-tailed primers.

abstract：:GASA-like genes form multigene families in diverse plant species and encode the proteins with a unique cysteine-rich domain (GASA domain). In our previously work, we cloned a GASA-like gene PRGL (Proline-rich GASA-like) from gerbera. Here we report the expression profiles of PRGL and the subcellular localization of PR...

journal_title：Molecular biology reports

authors： Peng J,Lai L,Wang X

更新日期：2010-10-01 00:00:00

abstract：:Actins are ubiquitous and highly conserved proteins that play key roles in cell formation and cellular activities. In this study, an actin gene was isolated from chickpea for the first time and designated as CarACT1 (for Cicer arietinum L. actin gene 1; Genbank accession no. EU529707). It encoded a putative protein wi...

journal_title：Molecular biology reports

authors： Peng H,Cheng H,Yu X,Shi Q,Zhang H,Li J,Ma H

更新日期：2010-02-01 00:00:00

abstract：:Bacterial artificial chromosome (BAC) library is an important genomic resource useful in targeted marker development, positional cloning, physical mapping and a substrate for genome sequencing for better understanding the genome organization of a species. The present manuscript elucidates the improvement in protocols ...

journal_title：Molecular biology reports

authors： Kumar R,Baisvar VS,Kushwaha B,Murali S,Singh VK

更新日期：2020-03-01 00:00:00

abstract：:Yangyin Tongnao granules (YYTNG) have been extensively applied in the treatment of brain injury, mainly due to its antioxidant effects, inhibition of apoptosis, and enhancement of blood circulation. To analyze the effect of YYTNG on the recovery of neurological function and neurogenesis in the peri-infarct area after ...

journal_title：Molecular biology reports

authors： Wang Y,Yang J,Du H,Zhang H,Wan H,He Y

更新日期：2019-08-01 00:00:00

abstract：:Studies investigating the association between glutathione S-transferase M1 (GSTM1) polymorphism and bladder cancer risk report conflicting results. The objective of this study was to quantitatively summarize the evidence for such a relationship. We performed a systematic search of the National Library of Medline and E...

journal_title：Molecular biology reports

authors： Zhang R,Xu G,Chen W,Zhang W

更新日期：2011-04-01 00:00:00

abstract：:Approximately 90% of patients with advanced breast cancer develop bone metastases; an event that results in severe decrease of quality of life and a drastic deterioration in prognosis. Therefore, to increase the survival of breast cancer patients, the development of new therapeutic strategies to impair metastatic proc...

journal_title：Molecular biology reports

authors： Vashum Y,Premsingh R,Kottaiswamy A,Soma M,Padmanaban A,Kalaiselvan P,Samuel S

更新日期：2020-12-08 00:00:00

abstract：:3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors has been shown to reduce the progression of renal disease independent of cholesterol-lowering effect, but the mechanism of potential protective effect remains unclear. Here, we investigate the effect of fluvastatin on activation of nuclear factor-κB ...

journal_title：Molecular biology reports

authors： Gao P,Wu X,Shui H,Jia R

更新日期：2012-04-01 00:00:00

abstract：:Acute and chronic viral hepatitis infections are corresponding to increase the risk of different types of hematological malignancies especially with leukemia. In this study the serological and molecular markers of hepatitis viruses were evaluated in patients with different types of leukemia in comparing with control g...

journal_title：Molecular biology reports

authors： Mirzaee M,Yaghobi R,Ramzi M,Roshan Nia M

更新日期：2012-02-01 00:00:00

abstract：:Molecular abnormalities in the 11p15.5 imprinted gene cluster lead to two different growth diseases: Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS). They are mainly caused by epigenetic alterations in one of the two imprinting 11p15 control regions (ICR1 and ICR2). These CpG-rich regions are diffe...

journal_title：Molecular biology reports

authors： Lukova M,Todorova A,Todorov T,Mitev V

更新日期：2013-01-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:Colorectal cancer (CRC) is one of the most common cancers, and rates of incidence and diagnosis of CRC have gradually increased. Carcinoembryonic antigen (CEA) is overexpressed in patients with CRC and is associated with cell adhesion, anoikis resistance, and promotion of metastasis to the liver. 5-Fluorouracil (5-FU)...

journal_title：Molecular biology reports

authors： Lee JH,Lee SW

更新日期：2019-08-01 00:00:00

abstract：:Gonadal dysgenesis (GD) is a rare cause of differences of sex development (DSD) with highly variable clinical and genetic conditions. Although identification of the causative genetic alterations can offer a clearer prognosis and personalized management to patients, more than 50% of the DSD cases still do not have an a...

journal_title：Molecular biology reports

authors： Nagy O,Kárteszi J,Hartwig M,Bertalan R,Jávorszky E,Erhardt É,Patócs A,Tornóczky T,Balogh I,Ujfalusi A

更新日期：2019-10-01 00:00:00

abstract：:Wild Solanum species are the important resources for potato improvement. With the availability of potato genome and sequencing progress, knowledge about genomic resources is essential for novel genes discovery. Hence, the aim of this study was to decipher draft genome sequences of unique potato genotypes i.e. somatic ...

journal_title：Molecular biology reports

authors： Tiwari JK,Rawat S,Luthra SK,Zinta R,Sahu S,Varshney S,Kumar V,Dalamu D,Mandadi N,Kumar M,Chakrabarti SK,Rao AR,Rai A

更新日期：2021-01-13 00:00:00

abstract：:This study investigated the role of the mevalonate pyrophosphate decarboxylase gene in the triterpene biosynthetic pathway of Ganoderma lucidum. The mevalonate pyrophosphate decarboxylase gene (mvd) was isolated using a degenerate primer-PCR technique. An analysis of the Gl-mvd transcription profile revealed a positiv...

journal_title：Molecular biology reports

authors： Shi L,Qin L,Xu Y,Ren A,Fang X,Mu D,Tan Q,Zhao M

更新日期：2012-05-01 00:00:00

abstract：:The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have been shown to be associated with carotid artery atherosclerosis. It remains unclear whether these two polymorphisms are associated with risk factors for cardiovascular disease (CVD) in hemodialysis (HD) patients. Therefor...

journal_title：Molecular biology reports

authors： Liu F,Mei X,Zhang Y,Qi H,Wang J,Wang Y,Jiang W,Zhang X,Yan H,Zhuang S

更新日期：2014-11-01 00:00:00

abstract：:β-Catenin plays a crucial role in embryonic development and responds to the activation of several signal transduction pathways. In this paper, in order to understand the functions of β-catenin gene in early embryonic development of Artemia sinica, the complete cDNA sequence was cloned for the first time using RACE tec...

journal_title：Molecular biology reports

authors： Li X,Hou L,Ma J,Liu Y,Zheng L,Zou X

更新日期：2012-01-01 00:00:00

abstract：:In attempting to produce the HAP, endoplasmic reticulum (ER) targeted apoptosis-inducing protein, as a GST-fusion protein we found that the expression of HAP, but not GST alone, induced bacterial cell death. The HAP protein inhibited the bacterial growth within 30 min after inducting HAP expression. The transmission e...

journal_title：Molecular biology reports

authors： Gan M,Qi Y,Wan Q,Kuang E,Liu Q,Liu X

更新日期：2004-09-01 00:00:00

abstract：:In clinical practice, most patients with non small cell lung cancer (NSCLC) who respond to tyrosine kinase inhibitors eventually progress because of an acquired resistance mutation, T790M, in epidermal growth factor receptor (EGFR). Thus, it is important to identify a new drug to reduce resistance. The aim of this stu...

journal_title：Molecular biology reports

authors： Zhu H,Cheng H,Ren Y,Liu ZG,Zhang YF,De Luo B

更新日期：2012-04-01 00:00:00

abstract：:In individuals with diabetes, a log linear relationship exists between cholesterol levels and cardiovascular disease. Type 2 diabetes (T2D) and Statins, a cholesterol lowering drug, have a complex relationship. Statins are potent modulators of CYP3A4 2 enzyme and endothelial nitric oxide synthase (eNOS) functions in a...

journal_title：Molecular biology reports

authors： Jamil K,Kandula V,Kandula R,Asimuddin M,Joshi S,Yerra SK

更新日期：2014-10-01 00:00:00

abstract：:High Mobility Group Box 1 (HMGB1) is a nuclear protein participating in chromatin architecture and transcriptional regulation. Recently, there is increasing evidence that HMGB1 contributes to the pathogenesis of chronic inflammatory and autoimmune diseases due to its pro-inflammatory and immunostimulatory properties. ...

journal_title：Molecular biology reports

authors： Pan HF,Wu GC,Li WP,Li XP,Ye DQ

更新日期：2010-03-01 00:00:00

abstract：:Alteration of the acrylamide:bisacrylamide ratio in the SDS-polyacrylamide gel used for Western blotting strongly improved the unambiguous detection of antibodies against 50-60 kDa autoantigens present in autoimmune patient sera. The relative migration of Ro52, the 56K autoantigen and calreticulin increased with reduc...

journal_title：Molecular biology reports

authors： Pruijn GJ,Bozic B,Schoute F,Rokeach LA,van Venrooij WJ

更新日期：1992-09-01 00:00:00

abstract：:Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indic...

journal_title：Molecular biology reports

authors： Hayashida K,Kohno S

更新日期：2009-07-01 00:00:00

abstract：:It is necessary that genetic markers or biomarkers can be used to predict resistance towards a wide range of infectious diseases. In the present study, we estimated the potential markers and measured their relationship with heritabilities of a wide range of immune traits. Polymorphisms in exon 13 of Mx1, intron 25 of ...

journal_title：Molecular biology reports

authors： Wang SJ,Liu WJ,Sargent CA,Zhao SH,Liu HB,Liu XD,Wang C,Hua GH,Yang LG,Affara NA,Zhang SJ

更新日期：2012-03-01 00:00:00

abstract：:Many environmental and genetic factors have been contributed to the development of systemic sclerosis (SSc). To determine whether IL-10 gene polymorphisms are associated with SSc, we conducted a meta-analysis approach. A total of eight studies involving 1,034 SSc cases and 1,815 controls were obtained by electronic da...

journal_title：Molecular biology reports

authors： Peng WJ,Wang BX,Pan HF,Tao JH,Zhang JQ,He Q,Xiao CC,Wang J

更新日期：2012-06-01 00:00:00

abstract：:1-aminocyclopropane-1-carboxylic acid oxidase (ACO) enzyme is a member of the Fe II-dependent family of oxidases/oxygenases which require Fe(2+) as a cofactor, ascorbate as a cosubstrate and CO(2) as an activator. This enzyme catalyses the terminal step in the plant signaling of ethylene biosynthetic pathway. A 948 bp...

journal_title：Molecular biology reports

authors： Jafari Z,Haddad R,Hosseini R,Garoosi G

更新日期：2013-02-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:In the present study, the expression levels of TRPM1, TRPM2, TRPM3, TRPM4, TRPM5, TRPM6, TRPM7, and TRPM8 genes were evaluated in heart tissues after ischemia/reperfusion (IR). For this study, 30 albino male Wistar rats were equally divided into three groups as follows: Group 1: control group (n:10), Group II: ischemi...

journal_title：Molecular biology reports

authors： Demir T,Yumrutas O,Cengiz B,Demiryurek S,Unverdi H,Kaplan DS,Bayraktar R,Ozkul N,Bagcı C

更新日期：2014-05-01 00:00:00

abstract：:The objective of this study was to determine hepatic expression levels of GHR, IGF1R, IGF1 and IGF2 genes in young growing gilts at different developmental ages (60-210 days) in five pig breeds: Polish Large White (PLW), Polish Landrace (PL), Pulawska (Pul), Duroc (Dur) and Pietrain (Pie). We studied the differences a...

journal_title：Molecular biology reports

authors： Pierzchała M,Pareek CS,Urbański P,Goluch D,Kamyczek M,Różycki M,Smoczynski R,Horbańczuk JO,Kurył J

更新日期：2012-03-01 00:00:00

abstract：:Natural killer cell (NK) is known as a major immune system in body through mediating cell death via several possible pathways, and one of three subpopulations of lymphocytes functioning as scavenger of tumor, virus infected cells etc. Our present results found that the SOD-contained silkworm larvae powder caused an en...

journal_title：Molecular biology reports

authors： Yue WF,Yao ML,Liu JM,Li GL,Li XH,Wu XF,Deng W,Sun HX,Zhou JY,Zhang CX,Miao YG

更新日期：2009-01-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00