Effects of the polymorphisms of Mx1, BAT2 and CXCL12 genes on immunological traits in pigs.

abstract：:The objective of this study was to determine hepatic expression levels of GHR, IGF1R, IGF1 and IGF2 genes in young growing gilts at different developmental ages (60-210 days) in five pig breeds: Polish Large White (PLW), Polish Landrace (PL), Pulawska (Pul), Duroc (Dur) and Pietrain (Pie). We studied the differences a...

journal_title：Molecular biology reports

authors： Pierzchała M,Pareek CS,Urbański P,Goluch D,Kamyczek M,Różycki M,Smoczynski R,Horbańczuk JO,Kurył J

更新日期：2012-03-01 00:00:00

abstract：:Increasing numbers of reports show that imprinted genes play a crucial role in fetal development, and uniparental embryos, which possess two paternally or two maternally derived pronuclei, are excellent tools for investigating the biological significance of imprinted genes. In the present study, to examine the in vitr...

journal_title：Molecular biology reports

authors： Hu M,TuanMu LC,Wei H,Gao F,Li L,Zhang S

更新日期：2015-02-01 00:00:00

abstract：:CREB-regulated transcription coactivator 3 (CRTC3) was a recently identified protein which played an important role in glucose and lipid metabolism. Previous research showed that the polymorphisms of CRTC3 were associated with obesity in Mexican-Americans. Data on that relationship in Chinese was unavailable so far. S...

journal_title：Molecular biology reports

authors： Ou Z,Wang G,Li Q,Ma Z,Dai M,Zou F

更新日期：2014-01-01 00:00:00

abstract：:Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple neoplasms. The main purpose of this study was to investigate the expression of these miRNAs in bladder cancer (BCa) and to analyze the association between their expression profiles and clinical and epidemiological parameters. Ninety BCa specim...

journal_title：Molecular biology reports

authors： Boubaker NS,Spagnuolo M,Trabelsi N,Said R,Gurtner A,Regazzo G,Ayed H,Blel A,Karray O,Saadi A,Rammeh S,Chebil M,Rizzo MG,Piaggio G,Ouerhani S

更新日期：2020-02-01 00:00:00

abstract：:45S ribosomal precursor RNA and large heterogeneous RNA molecules (greater than 45S) extracted from human leukemic cells were incubated in vitro with purified RNase III, which specifically attacks double-helical RNA regions. About 50% of the ribosomal precursor was cleaved into two major fragments sedimenting at 28S a...

journal_title：Molecular biology reports

authors： Torelli UL,Ferrari S,Torelli GM,Cadossi R,Ferrari S,Montagnani G,Narni F

更新日期：1977-12-01 00:00:00

abstract：:Whole-exome sequencing (WES) is an ideal method for the diagnosis of autosomal recessive diseases. The aim of this study was to evaluate the diagnostic power of WES in patients with autosomal recessive inheritance and to determine the relationship between genotype and phenotype. Retrospective screenings of 24 patients...

journal_title：Molecular biology reports

authors： Elmas M,Yıldız H,Erdoğan M,Gogus B,Avcı K,Solak M

更新日期：2019-02-01 00:00:00

abstract：:In plants, stomata play a pivotal role in the regulation of gas exchange and are distributed throughout the aerial epidermis. SDD1, a gene isolated from Arabidopsis thaliana has been demonstrated to specialize in stomatal density and distribution. In our present study, a comprehensive survey of global gene expression ...

journal_title：Molecular biology reports

authors： Xiao Y,Yu X,Chen J,Di P,Chen W,Zhang L

更新日期：2010-02-01 00:00:00

abstract：:High glycemic index diet can induce multiple diseases. Many research indicated that oxidative stress played important role in many pathological conditions. However, the impact of gene expression and dietary habit on oxidation process are still less clear. We used high-glucose diet to feed C57BL/6J mice for 4 weeks, me...

journal_title：Molecular biology reports

authors： Du D,Shi YH,Le GW

更新日期：2010-12-01 00:00:00

abstract：:Recently, circulating miRNAs have been reported as promising biomarkers for various pathologic conditions including cancer. Certain microRNAs (miRNAs) have been shown early diagnostic potential for many types of cancer. The objective of this study was to investigate the potential of certain serum/plasma miRNAs as nove...

journal_title：Molecular biology reports

authors： Giray BG,Emekdas G,Tezcan S,Ulger M,Serin MS,Sezgin O,Altintas E,Tiftik EN

更新日期：2014-07-01 00:00:00

abstract：:The spleen plays a crucial role in innate and adaptive immunity in bony fish. Consequently, this organ is well suited to assess the immune competence of an organism and hence provides useful information for comparison and classification of production traits of food fish, such as robustness and susceptibility. To gain ...

journal_title：Molecular biology reports

authors： Köbis JM,Rebl A,Kühn C,Goldammer T

更新日期：2013-02-01 00:00:00

abstract：:A full length spermidine synthase (PgSPD) cDNA was isolated and characterized from the root of Panax ginseng C. A. Meyer. The cDNA was 1,188 nucleotides long and had an open reading frame of 1,002 bp with a deduced amino acid sequence of 333 residues. The calculated molecular mass of the matured protein is approximate...

journal_title：Molecular biology reports

authors： Parvin S,Kim YJ,Pulla RK,Sathiyamoorthy S,Miah MG,Kim YJ,Wasnik NG,Yang DC

更新日期：2010-02-01 00:00:00

abstract：:Low levels of coenzyme Q10 (CoQ10) have been reported in the circulation of patients with breast cancer, particularly in metastatic features. Our objective was to study the correlation between plasma levels of CoQ10 and the tumoral expression levels of AMPK, PFKFB3, VEGF, and VEGFR2. This study was a part of consecuti...

journal_title：Molecular biology reports

authors： Abdi S,Montazeri V,Garjani A,Shayanfar A,Pirouzpanah S

更新日期：2020-04-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:The present meta-analysis of relevant case-control studies was conducted to investigate the possible relationships between genetic variations in the killer cell immunoglobulin-like receptor (KIR) gene clusters of the human KIR gene family and susceptibility to ankylosing spondylitis (AS). The following electronic data...

journal_title：Molecular biology reports

authors： Zuo HN,Wang ZL,Cui DR,Xin DJ

更新日期：2014-08-01 00:00:00

abstract：:We report here cloning and characterization of a novel human gene, termed VMP, which is a vesicular membrane protein. RT-PCR analysis shows that VMP is expressed exclusively in brain of the 16 tissues examined, suggesting that it is a neuron-specific membrane protein. The cDNA encodes 195 amino acid with a putative mo...

journal_title：Molecular biology reports

authors： Cheng C,Xu J,Ye X,Dai J,Wu Q,Zeng L,Wang L,Zhao W,Ji C,Gu S,Xie Y,Mao Y

更新日期：2002-09-01 00:00:00

abstract：:Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential in lots of important physiological processes, while, many marine species have no or limited ability of endogenous PUFA biosynthesis, normally due to the lack of key enzymes such as fatty acid desaturase (FAD). In this study, we isolated a scallop Chlamys ...

journal_title：Molecular biology reports

authors： Liu H,Guo Z,Zheng H,Wang S,Wang Y,Liu W,Zhang G

更新日期：2014-11-01 00:00:00

abstract：:Mitochondrial disorders are a frequent cause of neurological disability affecting children and adults. Traditionally, molecular diagnosis of mitochondrial diseases was mostly accomplished by the use of Sanger sequencing and PCR-RFLP. However, there are particular drawbacks associated with the use of these methods. Rec...

journal_title：Molecular biology reports

authors： Kauffman MA,Gonzlez-Morón D,Consalvo D,Westergaard G,Vazquez M,Mancini E,Taratuto AL,Rey R,Kochen S

更新日期：2012-06-01 00:00:00

abstract：:Fenpropathrin (FEN) is a pyrethroid insecticide. Mammals can be exposed to these compounds with food and water as non-target organisms. Pyrethroids are classified into two types depending on chemical structure and neurotoxic effects. FEN has features of Type I and Type II pyrethroids. There is data that pyrethroids ap...

journal_title：Molecular biology reports

authors： Jaremek M,Nieradko-Iwanicka B

更新日期：2020-06-01 00:00:00

abstract：:The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...

journal_title：Molecular biology reports

authors： Mastrangelo S,Sardina MT,Riggio V,Portolano B

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to identify molecular markers to be applied to marker-assisted selection. Three SNPs of the FASN gene were studied. PCR-RFLP was used for genotyping. The SNPs g.17924A>G, g.17860C>T and g.15603A>G all in the FASN gene were genotyped using the enzymes MscI, DdeI and Hae III, respectively. The ...

journal_title：Molecular biology reports

authors： de Souza FR,Chiquitelli MG,da Fonseca LF,Cardoso DF,da Silva Fonseca PD,de Camargo GM,Gil FM,Boligon AA,Tonhati H,Mercadante ME,de Albuquerque LG

更新日期：2012-12-01 00:00:00

abstract：:PCR low ionic strength single-strand conformation polymorphism (PCR-LIS-SSCP) and DNA sequencing methods were used to analyze the polymorphisms within the coding region of bovine ATP1A1 gene. A novel C/A mutation was identified at the nucleotide position 2789 of the ATP1A1 mRNA, but it was silent with respect to the a...

journal_title：Molecular biology reports

authors： Liu Y,Li D,Li H,Zhou X,Wang G

更新日期：2011-01-01 00:00:00

abstract：:Haemoglobin meseenger RNA was isolated from spleen erythroïd cells of anaemic rabbits. The mRNA fraction looks quite homogeneous when analyzed by sucrose gradient centrifugation; it sediments in the 9S region. When added to an ascites cell free system, spleen 9S RNA stimulates the incorporation of radioactive leucine ...

journal_title：Molecular biology reports

authors： Nokin P,Gautier E

更新日期：1973-06-01 00:00:00

abstract：:Lung cancer is the most common cause of cancer death worldwide. Smoking is known as the strongest single factor in the development of lung cancer. However, there are inherited genetic factors that cause different responses to cigarette smoking exposure among individuals. We tried to identify these differences in heavy...

journal_title：Molecular biology reports

authors： Lee M,Lee Y,Cho HJ,Hong J,Kwon SJ,Park CG,Lee HY,Son JW,Kang J

更新日期：2011-11-01 00:00:00

abstract：:We report the characterization of VvIAA9, an auxin/indole-3-acetic acid (Aux/IAA) protein, in grapevine (Vitis vinifera L.). VvIAA9 was expressed abundantly in leaves and berries. VvIAA9 transcription was drastically upregulated from anthesis to onset of ripening (termed véraison), in which berry diameter rapidly incr...

journal_title：Molecular biology reports

authors： Fujita K,Horiuchi H,Takato H,Kohno M,Suzuki S

更新日期：2012-07-01 00:00:00

abstract：:RACK1 is a crucial scaffold and anchoring protein, which plays a vital role in multiple signaling pathways of tumorigenesis. The aim of the present study was to identify the correlation between expressions of RACK1 and malignant degrees in colorectal carcinoma (CRC) patients. All together 157 CRC patients were enrolle...

journal_title：Molecular biology reports

authors： Jin S,Mu Y,Wang X,Liu Z,Wan L,Xiong Y,Zhang Y,Zhou L,Li L

更新日期：2014-05-01 00:00:00

abstract：:Several lines of evidence suggest that the ubiquitin-proteasome pathway is involved in sepsis-induced muscle catabolism. The gene expression of ubiquitin and several of the proteasome subunits was increased in muscle from both septic rats and patients. In other studies, the activity of isolated 20S proteasomes was sti...

journal_title：Molecular biology reports

authors： Hasselgren PO

更新日期：1999-04-01 00:00:00

abstract：:Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...

journal_title：Molecular biology reports

authors： Mancilla IA,Coatti GC,Biazi BI,Zanetti TA,Baranoski A,Marques LA,Corveloni AC,Lepri SR,Mantovani MS

更新日期：2019-12-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:Adipocyte death is important in obesity development. Understanding and prevention of adipocyte deaths may be a molecular approach in the treatment. In the study, we aimed to understand role of Niban gene, which acts as an anti-apoptotic molecule as a response to stress conditions, in adipocytes. 3T3-L1 adipocytes were...

journal_title：Molecular biology reports

authors： Cevik M,Gunduz MK,Deliorman G,Susleyici B

更新日期：2020-12-01 00:00:00

abstract：:The mechanism by which external Bax releases cytochrome c is still controversial and may also depend on the type of mitochondria and the actual localisation of cytochrome c. Outer membrane porin acquires high binding affinity for hexokinase by interacting with the adenine nucleotide translocator (ANT) in the contact s...

journal_title：Molecular biology reports

authors： Vyssokikh MY,Zorova L,Zorov D,Heimlich G,Jürgensmeier JJ,Brdiczka D

更新日期：2002-01-01 00:00:00