The increased expression of DEC1 gene is related to HIF-1α protein in gastric cancer cell lines.

abstract：:Putatively functional polymorphisms of one-carbon and xenobiotic metabolic pathways influence susceptibility for wide spectrum of diseases. The current study was aimed to explore gene-gene interactions among these two metabolic pathways in four diseases i.e. breast cancer, systemic lupus erythematosus (SLE), coronary ...

journal_title：Molecular biology reports

authors： Naushad SM,Vijayalakshmi SV,Rupasree Y,Kumudini N,Sowganthika S,Naidu JV,Ramaiah MJ,Rao DN,Kutala VK

更新日期：2015-07-01 00:00:00

abstract：:JAK/STAT signaling pathway is involved in many diseases, including autoimmune diseases, which are characterized by a close interconnection between immune and bone system. JAK/STAT pathway is involved in bone homeostasis and plays an important role in proliferation and differentiation of some cell types, including oste...

journal_title：Molecular biology reports

authors： Sanpaolo ER,Rotondo C,Cici D,Corrado A,Cantatore FP

更新日期：2020-11-01 00:00:00

abstract：:Olanzapine, an atypical antipsychotic medication, has been associated with weight gain and metabolic toxicity, especially in long term usage. Carnosic acid (CA), a major constituent of rosemary extract, has been shown to improve metabolic abnormalities. In this experiment, the effect of CA on olanzapine-induced obesit...

journal_title：Molecular biology reports

authors： Razavi BM,Abazari AR,Rameshrad M,Hosseinzadeh H

更新日期：2020-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is considered as a long-term autoimmune disorder. Gene polymorphism and oxidative stress might be involved in the pathogenesis of the disease. We aimed to determine the association between PON-1L55M polymorphism and its effects on inflammatory markers such as anti-cytroline circulated-peptide...

journal_title：Molecular biology reports

authors： Tanhapour M,Shahmohamadnejad S,Vaisi-Raygani A,Kiani A,Shakiba Y,Rahimi Z,Bahrehmand F,Shakiba E,Vaisi-Raygani AA,Alibakhshi R,Eivazi A,Pourmotabbed T

更新日期：2019-02-01 00:00:00

abstract：:Abiotic stresses such as salinity and drought have adverse effects on plants. In the present study, a Na(+)/H(+) antiporter gene homologue (LfNHX1) has been cloned from a local halophyte grass (Leptochloa fusca). The LfNHX1 cDNA contains an open reading frame of 1,623 bp that encodes a polypeptide chain of 540 amino a...

journal_title：Molecular biology reports

authors： Rauf M,Shahzad K,Ali R,Ahmad M,Habib I,Mansoor S,Berkowitz GA,Saeed NA

更新日期：2014-03-01 00:00:00

abstract：:In the present study, we investigated the differentially expressed proteins associated with ulcerative colitis (UC) using proteomic methods. Two-dimensional electrophoresis (2-DE) technology was performed to separate the total proteins of ulcerative tissues from those of the normal tissues of UC patients. PDQuest soft...

journal_title：Molecular biology reports

authors： Li N,Wang X,Zhang Y,Zhai J,Zhang T,Wei K

更新日期：2012-05-01 00:00:00

abstract：:The cell cycle is a complex and strictly controlled process, consisting of different phases. Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the dereg...

journal_title：Molecular biology reports

authors： Caglar HO,Biray Avci C

更新日期：2020-04-01 00:00:00

abstract：:Intrinsic bent DNA sites were identified in the 4289 bp segment encompassing the replication zone which directs DNA amplification and transcription of the C3-22 gene of Rhynchosciara americana. Restriction fragments showed reduced electrophoretic mobility in polyacrylamide gels. The 2D modeling of the 3D DNA path and ...

journal_title：Molecular biology reports

authors： Fiorini A,de Gouveia FS,de Soares MA,Stocker AJ,Ciferri RR,Fernandez MA

更新日期：2006-03-01 00:00:00

abstract：:Circular RNA (circRNA), a novel type of non-coding RNA that consists of a circular loop, has been demonstrated to act as a "sponge" for microRNAs (miRNAs). However, the role of circRNAs in keloid remains unknown. In this study, we investigated circRNA expression profiles in keloid to identify potential diagnostic and ...

journal_title：Molecular biology reports

authors： Shi J,Yao S,Chen P,Yang Y,Qian M,Han Y,Wang N,Zhao Y,He Y,Lyu L,Lu D

更新日期：2020-01-01 00:00:00

abstract：:Substantial epidemiological studies have shown an association of obesity with the common gynecological malignancy, endometrial cancer. The relevant interactions and contribution of estradiol and the adipose cytokine, leptin, in endometrial lesions are not completely understood. Suitable animal models to understand the...

journal_title：Molecular biology reports

authors： Shetty A,Venkatesh T,Tsutsumi R,Suresh PS

更新日期：2020-01-01 00:00:00

abstract：:The Cdx-2 polymorphism in VDR gene has been extensively investigated for association with cancer risk, however, results of different studies have been inconsistent. The objective of this study is to assess the relationship of the Cdx-2 polymorphism in VDR and cancer risk by meta-analysis. All eligible case-control stu...

journal_title：Molecular biology reports

authors： Huang J,Huang J,Ma Y,Wang H,Yang J,Xiong T,Du L

更新日期：2013-07-01 00:00:00

abstract：:Two calcium carbonate crystal polymorphs, aragonite and calcite, are the main inorganic components of mollusk shells. Some fossil evidences suggest that aragonite shell is more ancient than calcite shell for the Bivalvia. But, the molecular biology evidence for the above deduction is absent. In this study, we searched...

journal_title：Molecular biology reports

authors： Wang X,Li L,Zhu Y,Song X,Fang X,Huang R,Que H,Zhang G

更新日期：2014-11-01 00:00:00

abstract：:An ORF having a potential to code for a polypeptide of 79 amino acids has been identified within 993 nt sequence of 2 kb EcoRI-W fragment of Spodoptera litura nucleopolyhedrovirus (SpltNPV-I). Nucleotide and deduced amino acid sequence analyses showed its identity with the ubiquitin homologue of eukaryotes (79-80%), M...

journal_title：Molecular biology reports

authors： Jain M,Das RH

更新日期：2004-12-01 00:00:00

abstract：:This study is aimed to identify polymorphic microsatellite markers and establish their potential for population genetics studies in three carp (family cyprinidae; subfamily cyprininae) species, Labeo rohita, Catla catla and Cirrhinus mrigala through use of cyprinid primers. These species have high commercial value and...

journal_title：Molecular biology reports

authors： Masih P,Luhariya RK,Das R,Gupta A,Mohindra V,Singh RK,Srivastava R,Chauhan UK,Jena JK,Lal KK

更新日期：2014-08-01 00:00:00

abstract：:Glioma is the most aggressive primary brain tumor. We have previously provided evidence that IFITM3 promoted glioma cells migration. However, the mechanism of how IFITM3 regulates glioma cells invasion and whether IFITM3 participates in TGF-β-mediated glioma invasion are still unknown. In this paper, we proved that IF...

journal_title：Molecular biology reports

authors： Wang H,Tang F,Bian E,Zhang Y,Ji X,Yang Z,Zhao B

更新日期：2020-01-01 00:00:00

abstract：:GASA-like genes form multigene families in diverse plant species and encode the proteins with a unique cysteine-rich domain (GASA domain). In our previously work, we cloned a GASA-like gene PRGL (Proline-rich GASA-like) from gerbera. Here we report the expression profiles of PRGL and the subcellular localization of PR...

journal_title：Molecular biology reports

authors： Peng J,Lai L,Wang X

更新日期：2010-10-01 00:00:00

abstract：:The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...

journal_title：Molecular biology reports

authors： Zhang XM,Jing YP,Jia MY,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:Sepsis is one of the major health problems all over the world. Early diagnostic of sepsis is an attractive strategy to decrease the mortality of septic patients. However, an effective biomarker that fulfills all the necessary requirements for the accurate characterization of sepsis is still unavailable until now. In t...

journal_title：Molecular biology reports

authors： Liu J,Li J,Deng X

更新日期：2014-05-01 00:00:00

abstract：:Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...

journal_title：Molecular biology reports

authors： Vasconcelos GM,Gonçalves BA,Montalvão-de-Azevedo R,Thuler LC,Braga FH,Pombo-de-Oliveira MS,de Camargo B,Brazilian Embryonal Tumor Group.

更新日期：2014-09-01 00:00:00

abstract：:Se is an essential trace element and is found as a selenocysteine in the active site of Se-enzymes, such as glutathione peroxidase. tRNASec is first aminoacylated with serine by Ser RS and further is converted to selenocysteyl-tRNA by selenocysteine synthase. Mammalian selenocysteine tRNA has dual identities with Ser ...

journal_title：Molecular biology reports

authors： Mizutani T,Kanaya K,Ikeda S,Fujiwara T,Yamada K,Totsuka T

更新日期：1998-11-01 00:00:00

abstract：:Four housekeeping genes named Lbbeta-Actin1, Lbbeta-Actin2, Lbalpha-Tubulin, and LbGapdh were cloned from Liposcelis bostrychophila using the combined techniques of reverse transcriptase-PCR (RT-PCR) with rapid amplification of cDNA ends (RACE). The GenBank accession numbers were FJ196622, FJ447483, FJ595242, and FJ59...

journal_title：Molecular biology reports

authors： Jiang HB,Liu YH,Tang PA,Zhou AW,Wang JJ

更新日期：2010-02-01 00:00:00

abstract：:The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...

journal_title：Molecular biology reports

authors： Mastrangelo S,Sardina MT,Riggio V,Portolano B

更新日期：2012-01-01 00:00:00

abstract：:Long-term ketamine abuse is known to affect the lower urinary tract and produce symptoms of cystitis. However, the pathophysiology and causative mechanism of the changes in bladder function remain unclear. The present study aimed to investigate the existence of ketamine-induced cystitis in a rat model and characterize...

journal_title：Molecular biology reports

authors： Gu D,Huang J,Yin Y,Shan Z,Zheng S,Wu P

更新日期：2014-11-01 00:00:00

abstract：:FK-506 binding proteins (FKBPs) belong to the peptidyl-prolyl cis/trans isomerase superfamily (PPIases, EC: 5.2.1.8) which catalyzes the interconversion of peptidyl-prolyl bonds while they can also act on polypeptides, as folding helper enzymes. Here, we biochemically characterize two recombinant FKBPs, AvfkbA1 and Av...

journal_title：Molecular biology reports

authors： Dimou M,Zografou C,Venieraki A,Katinakis P

更新日期：2012-12-01 00:00:00

abstract：:J The [Ca2+] regulation of contractile ATPase flux, Jp, in skeletal muscle was analysed by computation of the Response R(Jp) Ca2+ for a 10 Hz range of electrical stimulation frequencies. Results of our analysis of the kinetic controls in ATP free energy metabolism in a network model of contracting muscle (J.A.L. Jenes...

journal_title：Molecular biology reports

authors： Jeneson JA

更新日期：2002-01-01 00:00:00

abstract：:The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Many published studies have evaluated the associat...

journal_title：Molecular biology reports

authors： Zhao E,Cui D,Yuan L,Lu W

更新日期：2012-04-01 00:00:00

abstract：:Transcriptional activity is closely associated with DNA methylation and chromatin remodelling. Evidence is emerging that a family of methylation specific (methyl-CpG binding domain, MBD) proteins have the capacity to bind to methylated sequences and repress transcription. Recent advances in this area reveal that many ...

journal_title：Molecular biology reports

authors： El-Osta A,Baker EK,Wolffe AP

更新日期：2001-01-01 00:00:00

abstract：:The genes of E. coli are located on a circular chromosome of 4.6 million basepairs. This 1.6 mm long molecule is compressed into a nucleoid to fit inside the 1-2 microm cell in a functional format. To examine the role of DNA supercoiling as nucleoid compaction force we modulated the activity of DNA gyrase by electroni...

journal_title：Molecular biology reports

authors： Stuger R,Woldringh CL,van der Weijden CC,Vischer NO,Bakker BM,van Spanning RJ,Snoep JL,Westerhoff HV

更新日期：2002-01-01 00:00:00

abstract：:The extremely low-frequency magnetic fields (ELF-EMF) are generated by electrical devices and power systems (1 to 300 Hz). In recent decades, exposure to ELF-EMF has emerged potential concerns on public health. Here, we discuss recent progress in the understanding of ELF-EMF biology with a focus on mechanisms of ELF-E...

journal_title：Molecular biology reports

authors： Karimi A,Ghadiri Moghaddam F,Valipour M

更新日期：2020-07-01 00:00:00

abstract：:Chrysanthemum indicum L. is a traditional oriental medicinal herb prepared as a tea from flowers that have been used in China and South Korea since ancient times. It has a long history in the treatment of hypertension, inflammation, and respiratory diseases. Among Chrysanthemum species, C. indicum has more active chem...

journal_title：Molecular biology reports

authors： Abid S,Kaliraj L,Arif MH,Hurh J,Ahn JC,Yang DC,Jung SK

更新日期：2020-10-01 00:00:00