The dual identities of mammalian tRNA(Sec) for SerRS and selenocysteine synthase.

abstract：:Sepsis is one of the major health problems all over the world. Early diagnostic of sepsis is an attractive strategy to decrease the mortality of septic patients. However, an effective biomarker that fulfills all the necessary requirements for the accurate characterization of sepsis is still unavailable until now. In t...

journal_title：Molecular biology reports

authors： Liu J,Li J,Deng X

更新日期：2014-05-01 00:00:00

abstract：:We report here a cDNA and its deduced amino acid sequence encoding a cathepsin D-like, aspartic protease from Chlamys farreri (denoted as CfCD) by expressed sequence tag and rapid amplification of cDNA ends techniques. The cDNA of CfCD consisted of 1,810 nucleotides with a canonical polyadenylation signal sequence AAT...

journal_title：Molecular biology reports

authors： Li C,Zhang H,Li L,Song L

更新日期：2010-03-01 00:00:00

abstract：:Iron may be implicated in the generation of oxidative stress by the catalyzing the Haber-Weiss or Fenton reaction. On the other hand, oxidative stress has been implicated in the pathogenesis of age-related macular degeneration (AMD) and heme oxygenase-1 (HO-1), encoded by the HMOX1 gene and heme oxygenase-2 (HO-2), en...

journal_title：Molecular biology reports

authors： Synowiec E,Szaflik J,Chmielewska M,Wozniak K,Sklodowska A,Waszczyk M,Dorecka M,Blasiak J,Szaflik JP

更新日期：2012-03-01 00:00:00

abstract：:Penicillin V is a bacteriolytic β-lactam antibiotic drug. In the present work, we investigated the inhibitory effect of Penicillin V on the activity of mushroom tyrosinase for the first time. The molecular mechanism for the inhibition of tyrosinase by Penicillin V was investigated by means of kinetics analysis, fluore...

journal_title：Molecular biology reports

authors： Dong X,Wang S,Xu L,Lin J,Xu X

更新日期：2020-02-01 00:00:00

abstract：:Transition from laying to incubation behavior in chicken is an interesting topic in reproductive biology. The decline of incubation behavior in chicken population has led to considerable phenotypic differences in reproductive traits between breeds. However, the exact genetic mechanism of the reproductive phase transit...

journal_title：Molecular biology reports

authors： Shen X,Bai X,Xu J,Zhou M,Xu H,Nie Q,Lu X,Zhang X

更新日期：2016-09-01 00:00:00

abstract：:The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Many published studies have evaluated the associat...

journal_title：Molecular biology reports

authors： Zhao E,Cui D,Yuan L,Lu W

更新日期：2012-04-01 00:00:00

abstract：:The aim of this study was to determine whether the Glutathione S-transferase M1 (GSTM1) and P1 (GSTP1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). Meta-analysis was performed on the associations between the GSTM1 and GSTP1 null genotypes and RA, and on the association between smoking or seroposit...

journal_title：Molecular biology reports

authors： Song GG,Bae SC,Lee YH

更新日期：2012-12-01 00:00:00

abstract：:Evidence indicates that both S-adenosylmethionine (SAMe) metabolism and intramuscular fat are associated with insulin resistance and type II diabetes. However, it is still unknown whether SAMe have effects on intramuscular adipogenesis. The present study investigated the roles of SAMe in the adipogenic differentiation...

journal_title：Molecular biology reports

authors： Yue T,Fang Q,Yin J,Li D,Li W

更新日期：2010-10-01 00:00:00

abstract：:Seed development is a complex process controlled by temporal and spatial expression of many transcription factors (TF) inside the developing seed. In the present study, transcript profiles of all the 30 members of rice DofTFs from flowering to seed development stages were analyzed. It was found that 16 Dof genes besid...

journal_title：Molecular biology reports

authors： Gaur VS,Singh US,Kumar A

更新日期：2011-04-01 00:00:00

abstract：:Studies investigating the association between glutathione S-transferase M1 (GSTM1) polymorphism and bladder cancer risk report conflicting results. The objective of this study was to quantitatively summarize the evidence for such a relationship. We performed a systematic search of the National Library of Medline and E...

journal_title：Molecular biology reports

authors： Zhang R,Xu G,Chen W,Zhang W

更新日期：2011-04-01 00:00:00

abstract：:We have previously shown that angiotensin-converting enzyme (ACE) gene D allele is an independent risk factor for early onset coronary artery disease (CAD). Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. Regarding the high...

journal_title：Molecular biology reports

authors： Vaisi-Raygani A,Rahimi Z,Tavilani H,Vaisi-Raygani H,Kiani A,Aminian M,Shakiba E,Shakiba Y,Pourmotabbed T

更新日期：2012-03-01 00:00:00

abstract：:The complete mitochondrial genome of Pseudochauhanea macrorchis was determined and compared with other monogenean mitochondrial genomes from GenBank. The circular genome was 15,031 bp in length and encoded 36 genes (12 protein-coding genes, two ribosomal RNAs, and 22 transfer RNAs) typically found in flatworms. Struct...

journal_title：Molecular biology reports

authors： Zhang J,Wu X,Xie M,Li A

更新日期：2012-08-01 00:00:00

abstract：:The study was done to identify the candidate causal single nucleotide polymorphisms (SNPs) and candidate causal mechanisms that contribute to Parkinson's disease (PD) susceptibility and to generate a SNP to ene to pathway hypothesis using an analytical pathway-based approach. We used a PD genome-wide association study...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-03-01 00:00:00

abstract：:As-NUPR1, a stress-related protein, plays an important role in post-diapause during embryonic development in the brine shrimp Artemia sinica. In the present study, successful expression of As-NUPR1 from the cDNA sequence isolated from A. sinica was demonstrated using a prokaryotic expression system. The recombinant pr...

journal_title：Molecular biology reports

authors： Zhang R,Yao F,Cheng C,Chen Y,Lv Y,Li Z,Zhao N,Wang T,Xin W,Zou X,Hou L

更新日期：2014-05-01 00:00:00

abstract：:Rat liver chromatin activated by partial hepatectomy is more susceptible to the action of DNAse I than control chromatin isolated from intact liver. The study on the transfer of chromatin material to the acid-soluble fraction reveals a higher rate of activated chromatin degradation. Activated chromatin shows also an i...

journal_title：Molecular biology reports

authors： Batova IN,Fedoseeva GE,Zelenin AV

更新日期：1979-12-31 00:00:00

abstract：:Schistosomiasis, a disease caused by helminth parasites of genus Schistosoma. Its treatment intensively depends on single drug, praziquantel which increases the risk of development of drug-resistant parasite. Inhibitors of human HDAC are profoundly reported as novel anti-cancer drugs and used as new anit-parasitic age...

journal_title：Molecular biology reports

authors： Singh R,Pandey PN

更新日期：2015-03-01 00:00:00

abstract：:F-box proteins are key components of the ubiquitin (Ub)/26S proteasome pathway that mediates selective degradation of regulatory proteins involved in a wide variety of cellular processes affecting eukaryotic cells. In plants, F-box genes form one of the largest multigene superfamilies and control many important biolog...

journal_title：Molecular biology reports

authors： Paquis S,Mazeyrat-Gourbeyre F,Fernandez O,Crouzet J,Clément C,Baillieul F,Dorey S

更新日期：2011-06-01 00:00:00

abstract：:Birch (Betula platyphylla), an eminent tree species in Northeast and Inner Mongolia of China, has been widely used in architecture, furniture, and paper making in recent years. In order to retrieve genes involved in early development of B. platyphylla male inflorescence, RNA populations extracted from early and late d...

journal_title：Molecular biology reports

authors： Xing L,Liu XM

更新日期：2012-02-01 00:00:00

abstract：:The glycosylation of UDP-glucosyltransferases (UGTs) is of great importance in the control and elimination of both endogenous and exogenous toxins. Bm-UGT10286 (UGT86) is the sole provider of UGT activity against the 5-O position of quercetin and directly influences the formation of green pigment in the Bombyx cocoon....

journal_title：Molecular biology reports

authors： Xu X,Wang M,Wang Y,Sima Y,Zhang D,Li J,Yin W,Xu S

更新日期：2013-05-01 00:00:00

abstract：:ATP-binding cassette transporter A1 (ABCA1) modulates plasma levels of high density lipoprotein (HDL), a cardiovascular protecting factor. Tree shrew was considered to be an animal protected from atherosclerosis characterized by high proportion of HDL in plasma. The cDNA clones and expression of tree shrew ABCA1 was i...

journal_title：Molecular biology reports

authors： Zeng WW,Zhou B,Liu HR,Sun GT,Chen BS

更新日期：2009-03-01 00:00:00

abstract：:In plants, stomata play a pivotal role in the regulation of gas exchange and are distributed throughout the aerial epidermis. SDD1, a gene isolated from Arabidopsis thaliana has been demonstrated to specialize in stomatal density and distribution. In our present study, a comprehensive survey of global gene expression ...

journal_title：Molecular biology reports

authors： Xiao Y,Yu X,Chen J,Di P,Chen W,Zhang L

更新日期：2010-02-01 00:00:00

abstract：:The difference in sensitivity of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes to inhibition by the Phytolacca americana protein (PAP) has been found to be linked to the source of the supernatant enzyme fraction and not the ribosomes. In the presence of reticulocyte supernatant e...

journal_title：Molecular biology reports

authors： Suits JP,Irvin JD

更新日期：1976-04-01 00:00:00

abstract：:The new transcriptomes provided comprehensive sequence profiling data of transcriptomic variation during vernalization in Lily Asiatic Hybrids 'Tiny ghost'. A number of 52,277,184 sequencing raw reads totaling 5.11 Gbp of the chilling treatment (4 °C) sample and 39,466,176 sequencing raw reads totaling 3.85 Gbp of roo...

journal_title：Molecular biology reports

authors： Huang J,Liu X,Wang J,Lü Y

更新日期：2014-06-01 00:00:00

abstract：:Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium lat...

journal_title：Molecular biology reports

authors： Sinha VB,Grover A,Singh S,Pande V,Ahmed Z

更新日期：2014-09-01 00:00:00

abstract：:Olanzapine, an atypical antipsychotic medication, has been associated with weight gain and metabolic toxicity, especially in long term usage. Carnosic acid (CA), a major constituent of rosemary extract, has been shown to improve metabolic abnormalities. In this experiment, the effect of CA on olanzapine-induced obesit...

journal_title：Molecular biology reports

authors： Razavi BM,Abazari AR,Rameshrad M,Hosseinzadeh H

更新日期：2020-10-01 00:00:00

abstract：:Our previous study revealed that CRB3 protein expression was reduced in clear cell renal cell carcinoma (ccRCC) and was associated with TNM stage, pathological grade, and poor prognosis of ccRCC. This study aimed to investigate if DNA methylation of CRB3 decreases its expression, subsequently leading to the progressio...

journal_title：Molecular biology reports

authors： Li P,Liu J,Li J,Liu P

更新日期：2019-08-01 00:00:00

abstract：:Cell-based approaches offer a potential therapeutic strategy for appropriate bone manufacturing. Capable of differentiating into multiple cell types especially osteoblasts spontaneously, unrestricted somatic stem cell (USSC) seems to be a suitable candidate. Recent studies have shown the involvement of microRNAs in se...

journal_title：Molecular biology reports

authors： Bakhshandeh B,Soleimani M,Hafizi M,Paylakhi SH,Ghaemi N

更新日期：2012-07-01 00:00:00

abstract：:DNA-, RNA- and protein synthesis have been studied in Mycobacterium smegmatis cells infected with phage I3. The macromolecular synthesis continued until the end of latent period. Early RNA and protein synthesis were necessary prior to the commencement of DNA replication. The infecting phage DNA sedimented as larger th...

journal_title：Molecular biology reports

authors： Nagaraja V,Gopinathan KP

更新日期：1981-11-30 00:00:00

abstract：:α-Synuclein is a presynaptic neuronal protein that is abundant in the human brain and is linked genetically and neuropathologically to Parkinson's disease (PD). The E46K mutation of the α-synuclein gene has been linked to autosomal dominant early-onset of PD. Crocin is a carotenoid chemical compound of saffron that ha...

journal_title：Molecular biology reports

authors： Ghasemi Tigan M,Ghahghaei A,Lagzian M

更新日期：2019-08-01 00:00:00

abstract：:In plants, pathogenesis-related 1 protein (PR1) is considered as important defense protein. The production and accumulation of PR proteins in plants are one of the important responses to several biotic and abiotic stresses. In this regard, PR1 gene was isolated from Triticum turgidum ssp durum and was named as TdPR1.2...

journal_title：Molecular biology reports

authors： Ghorbel M,Zribi I,Missaoui K,Drira-Fakhfekh M,Azzouzi B,Brini F

更新日期：2020-12-13 00:00:00