Transcriptomic analysis of Asiatic lily in the process of vernalization via RNA-seq.

abstract：:Several mechanisms are involved in the loss of cellular integrity and tissue destructions in various brain regions during ischemic insult. The affected brain employs various self-repair mechanisms during the poststroke recovery. Therefore, the current study involves time course changes in different brain regions follo...

journal_title：Molecular biology reports

authors： Kapoor M,Sharma S,Sandhir R,Nehru B

更新日期：2019-12-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) incidence is fast-growing especially in countries highly prevalent with viral hepatitis. Its poor prognosis has driven the research toward the discovery of sensitive markers for early detection. We investigated the usefulness of serum Transforming growth factor-beta1 (TGF-β1), Glypican-3...

journal_title：Molecular biology reports

authors： Ibrahim GH,Mahmoud MA,Aly NM

更新日期：2013-12-01 00:00:00

abstract：:ERBB2/HER2/NEU, a member of the epidermal growth factor receptor family, is overexpressed in more than 25 % of non-small cell lung cancer and is considered to be a significant and independent prognostic factor in lung cancer. Here we generated a lung specific HER2 overexpressing transgenic mouse model. In this model, ...

journal_title：Molecular biology reports

authors： Zeng S,Yang Y,Tan Y,Lu C,Pan Y,Chen L,Lu G

更新日期：2012-08-01 00:00:00

abstract：:Identifying patients at high risk of metastasis is a major challenge in lung adenocarcinoma (ADC) therapy, therefore discovery of noninvasive biomarkers and therapeutic targets is urgent. We found significant differences between the secretomes of differentially expressed proteins in lung ADC cell lines, clinical tissu...

journal_title：Molecular biology reports

authors： Liu Z,Gao Y,Hao F,Lou X,Zhang X,Li Y,Wu D,Xiao T,Yang L,Li Q,Qiu X,Wang E

更新日期：2014-11-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:microRNAs (miRNAs) are a new class of small non-coding RNAs that function as tumor suppressors or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNA may contribute to cancer development. We hypothesized that genetic variations of the miRNA could be associated with the risk of hepatitis B virus (HBV)-related he...

journal_title：Molecular biology reports

authors： Xiang Y,Fan S,Cao J,Huang S,Zhang LP

更新日期：2012-06-01 00:00:00

abstract：:In our research, signal transducer and activator of transcription 5b (STAT5b) gene was studied as candidate gene associated with body weight and reproductive traits of Jinghai Yellow chicken. Single nucleotide polymorphisms (SNPs) of STAT5b gene were examined in both Jinghai Yellow chicken and three reference chicken ...

journal_title：Molecular biology reports

authors： Zhao XH,Wang JY,Zhang GX,Wei Y,Gu YP,Yu YB

更新日期：2012-04-01 00:00:00

abstract：:An extensive study on spontaneous and 5-Fluorodeoxyuridine induced fragile sites identified Xq31 in cattle (Bos taurus) and (Xq24, Xq26) in sheep (Ovis aries) in addition to several autosomal fragile sites (under publication). A ZOO-FISH study using three cloned human fragile-X probes with CCG/CGG(n) trinucleotide rep...

journal_title：Molecular biology reports

authors： Ali A,Thomsen PD,Babar ME

更新日期：2009-03-01 00:00:00

abstract：:Development of a rapid and accurate quantification method for the detection of microRNAs (miRNAs) has been desired, in particular, when they are differently expressed in normal and pathological conditions. However, various methods for the quantification of small non-coding RNAs as well as miRNAs have been described. T...

journal_title：Molecular biology reports

authors： Mohammadi-Yeganeh S,Paryan M,Mirab Samiee S,Soleimani M,Arefian E,Azadmanesh K,Mostafavi E,Mahdian R,Karimipoor M

更新日期：2013-05-01 00:00:00

abstract：:Radiotherapy is an effective treatment for some esophageal cancers, but the molecular mechanisms of radiosensitivity remain unknown. Ubiquitin-like with PHD and ring finger domains 1 (UHRF1) is a novel nuclear protein which is overexpressed in various cancers but not yet examined in esophageal squamous cell carcinoma ...

journal_title：Molecular biology reports

authors： Yang C,Wang Y,Zhang F,Sun G,Li C,Jing S,Liu Q,Cheng Y

更新日期：2013-09-01 00:00:00

abstract：:Drought is one of the major abiotic stresses that affect productivity in soybean (Glycine max L.) Several genes induced by drought stress include functional genes and regulatory transcription factors. The Arabidopsis thaliana DREB1D transcription factor driven by the constitutive and ABA-inducible promoters was introd...

journal_title：Molecular biology reports

authors： Guttikonda SK,Valliyodan B,Neelakandan AK,Tran LS,Kumar R,Quach TN,Voothuluru P,Gutierrez-Gonzalez JJ,Aldrich DL,Pallardy SG,Sharp RE,Ho TH,Nguyen HT

更新日期：2014-12-01 00:00:00

abstract：:Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple neoplasms. The main purpose of this study was to investigate the expression of these miRNAs in bladder cancer (BCa) and to analyze the association between their expression profiles and clinical and epidemiological parameters. Ninety BCa specim...

journal_title：Molecular biology reports

authors： Boubaker NS,Spagnuolo M,Trabelsi N,Said R,Gurtner A,Regazzo G,Ayed H,Blel A,Karray O,Saadi A,Rammeh S,Chebil M,Rizzo MG,Piaggio G,Ouerhani S

更新日期：2020-02-01 00:00:00

abstract：:RNA polymerase III in an extract of HeLa cells transcribes RNA 5S in size from genomic bovine DNA template. This RNA represents a major fraction of the RNA synthesized. 5S RNA is not transcribed from bovine chromatin at equivalent concentrations and RNA the size of tRNA or tRNA precursor is not detected. At low UTP co...

journal_title：Molecular biology reports

authors： Furth JJ,Su CY

更新日期：1983-08-01 00:00:00

abstract：:Despite advantageous antitumor properties of doxorubicin, the considerable cytotoxicity of this chemotherapeutic agent has made it necessary to develop combination treatment strategies. The aim of the current study was to investigate the possible synergism between dendrosomal nanocurcumin (DNC) and doxorubicin in elic...

journal_title：Molecular biology reports

authors： Mahjoub MA,Bakhshinejad B,Sadeghizadeh M,Babashah S

更新日期：2017-08-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-α) and interleukin 1 beta (IL-1β) genetic variants which resulting in TNF-α and IL-1 overproduction may increase susceptibility to autoimmune diseases such as atherosclerosis. We have studied the association of TNF-α G308A and IL-1β (+3953) C/T polymorphism with myocardial infarction i...

journal_title：Molecular biology reports

authors： Zeybek U,Toptas B,Karaali ZE,Kendir M,Cakmakoglu B

更新日期：2011-11-01 00:00:00

abstract：:The interleukin (IL)-1β-511 C/T polymorphism has been shown to be functional and to contribute to the risk of gastric cancer. However, the relationship between the IL-1β-511 C/T polymorphism and gastric carcinogenesis remains inconclusive. A systematical electronic search was conducted of the MEDLINE, EMBASE, and CENT...

journal_title：Molecular biology reports

authors： Park MJ,Hyun MH,Yang JP,Yoon JM,Park S

更新日期：2015-01-01 00:00:00

abstract：:Cold stress adversely affects the growth and development of seedling of spring soybean. Revealing responses in seedling to cold stress at proteomic level will help us to breed cold-tolerant spring soybean cultivars. In this study, to understand the responses, a proteomic analysis on the leaves of seedlings of one cold...

journal_title：Molecular biology reports

authors： Tian X,Liu Y,Huang Z,Duan H,Tong J,He X,Gu W,Ma H,Xiao L

更新日期：2015-03-01 00:00:00

abstract：:Interferon gamma (IFN-γ) is an important immunoregulatory cytokine that has a central role against viral and bacterial infections. In this study, the cDNA encoding 141 amino acids of mature IFN-γ from mice splenocytes was cloned in a prokaryotic expression vector pQE 30. Optimization of expression conditions resulted ...

journal_title：Molecular biology reports

authors： Kumar M,Singh M,Singh SB

更新日期：2014-10-01 00:00:00

abstract：:Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...

journal_title：Molecular biology reports

authors： Vasconcelos GM,Gonçalves BA,Montalvão-de-Azevedo R,Thuler LC,Braga FH,Pombo-de-Oliveira MS,de Camargo B,Brazilian Embryonal Tumor Group.

更新日期：2014-09-01 00:00:00

abstract：:This study investigated the role of the mevalonate pyrophosphate decarboxylase gene in the triterpene biosynthetic pathway of Ganoderma lucidum. The mevalonate pyrophosphate decarboxylase gene (mvd) was isolated using a degenerate primer-PCR technique. An analysis of the Gl-mvd transcription profile revealed a positiv...

journal_title：Molecular biology reports

authors： Shi L,Qin L,Xu Y,Ren A,Fang X,Mu D,Tan Q,Zhao M

更新日期：2012-05-01 00:00:00

abstract：:Protein profile of the skeletal muscle of Takifugu rubripes, a kind of pufferfish, was carried out with two-dimensional polyacrylamide gel electrophoresis (2-DE). Among the 112 protein spots detected in a silver-stained 2-D polyacrylamide gel, 33 were analyzed by Matrix Assisted Laser Desorption Ionisation tandem time...

journal_title：Molecular biology reports

authors： Lu J,Zheng J,Liu H,Li J,Chen H,Chen K

更新日期：2010-06-01 00:00:00

abstract：:Local domestic chicken populations are of paramount importance as a source of protein in developing countries. Bangladesh possesses a large number of native chicken populations which display a broad range of phenotypes well adapted to the extreme wet and hot environments of this region. This and the fact that wild jun...

journal_title：Molecular biology reports

authors： Bhuiyan MS,Chen S,Faruque S,Bhuiyan AK,Beja-Pereira A

更新日期：2013-06-01 00:00:00

abstract：:It has been demonstrated that ACSL3 and ACSL5 play important roles in fat metabolism. To investigate the primary functions of ACSL3 and ACSL5 and to evaluate their expression levels during goose fatty liver development, we cloned the ACSL3 and ACSL5 coding domain sequences (CDSs) of geese using RT-PCR and analyzed the...

journal_title：Molecular biology reports

authors： He H,Liu HH,Wang JW,Lv J,Li L,Pan ZX

更新日期：2014-01-01 00:00:00

abstract：:Testis development is a highly regulated sequence of developmental process that spans from the establishment of germ cell lineage during embryonic development to the periodic wave of spermatogenesis in adulthood. The normal development of testes and the fertility of male animals require specific cell types to respond ...

journal_title：Molecular biology reports

authors： Fan YS,Hu YJ,Yang WX

更新日期：2012-04-01 00:00:00

abstract：:Calcific mitral valve stenosis (MVS) is a common disease characterized by extensive remodeling of the extracellular matrix via matrix metalloproteinases (MMPs). The mechanism of calcification due to extensive matrix remodeling remains unclear. In this study, we investigated the relationship between MMP-3, tissue inhib...

journal_title：Molecular biology reports

authors： Aloui S,Zidi W,Ouali S,Guizani I,Hadj-Taieb S,Mourali MS,Feki M,Allal-Elasmi M

更新日期：2018-12-01 00:00:00

abstract：:In view of high mortality associated with coronary artery disease (CAD), development of an early predicting tool will be beneficial in reducing the burden of the disease. The database comprising demographic, conventional, folate/xenobiotic genetic risk factors of 648 subjects (364 cases of CAD and 284 healthy controls...

journal_title：Molecular biology reports

authors： Naushad SM,Hussain T,Indumathi B,Samreen K,Alrokayan SA,Kutala VK

更新日期：2018-10-01 00:00:00

abstract：:Osteocytic potentiality of human CD34+ stem cells explored in the present study by generating in vitro agarose gel 3D model to understand the bone ossification process. The G-CSF and IL-3 mobilized human CD34+ stem cells isolated apheretically from donor peripheral blood and purity of the cells was assessed by FACS an...

journal_title：Molecular biology reports

authors： Srikanth L,Sunitha MM,Kumar PS,Chandrasekhar C,Vengamma B,Sarma PV

更新日期：2016-11-01 00:00:00

abstract：:TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin processing recently, enzymes encoded by PCSK1 and PCSK2 are reported to play an important role in the process of proinsulin conversion. To investigate whether the single nucleotide polymorphisms...

journal_title：Molecular biology reports

authors： Zheng X,Ren W,Zhang S,Liu J,Li S,Li J,Yang P,He J,Su S,Li P

更新日期：2012-01-01 00:00:00

abstract：:The genes of E. coli are located on a circular chromosome of 4.6 million basepairs. This 1.6 mm long molecule is compressed into a nucleoid to fit inside the 1-2 microm cell in a functional format. To examine the role of DNA supercoiling as nucleoid compaction force we modulated the activity of DNA gyrase by electroni...

journal_title：Molecular biology reports

authors： Stuger R,Woldringh CL,van der Weijden CC,Vischer NO,Bakker BM,van Spanning RJ,Snoep JL,Westerhoff HV

更新日期：2002-01-01 00:00:00

abstract：:α-Synuclein is a presynaptic neuronal protein that is abundant in the human brain and is linked genetically and neuropathologically to Parkinson's disease (PD). The E46K mutation of the α-synuclein gene has been linked to autosomal dominant early-onset of PD. Crocin is a carotenoid chemical compound of saffron that ha...

journal_title：Molecular biology reports

authors： Ghasemi Tigan M,Ghahghaei A,Lagzian M

更新日期：2019-08-01 00:00:00