Molecular cloning of the goose ACSL3 and ACSL5 coding domain sequences and their expression characteristics during goose fatty liver development.

abstract：:The binding of a cell nucleus stain, hematoxylin (HTL), to bovine serum albumin (BSA) was studied by spectroscopy including fluorescence spectra, UV-Visible absorption, circular dichroism (CD) spectra, synchronous and three-dimensional fluorescence spectra. The results indicated that the binding had led to static fluo...

journal_title：Molecular biology reports

authors： Zhang HX,Gao S,Xiong ZY,Liu SP

更新日期：2009-11-01 00:00:00

abstract：:Safe harbor loci allow predicable integration of a transgene into the genome without perturbing endogenous gene activity and for decades have been exploited in the mouse to investigate gene function, generate humanised models and create tissue specific reporter and Cre recombinase expressing lines. Herein, we show tha...

journal_title：Molecular biology reports

authors： Browning J,Rooney M,Hams E,Takahashi S,Mizuno S,Sugiyama F,Fallon PG,Kelly VP

更新日期：2020-02-01 00:00:00

abstract：:Brucella cell surface protein (BCSP31) is potentially useful for diagnosing brucellosis. We aimed to establish a monoclonal antibody (MAb) against Brucella melitensis BCSP31 and to investigate its distribution in diagnosis. Soluble recombinant BCSP31 was successfully expressed and purified. Two MAbs (1F1 and 1E5) agai...

journal_title：Molecular biology reports

authors： Zhang L,Wu XA,Zhang FL,An CH,Sun YX,Bai WT,Xu ZK

更新日期：2012-01-01 00:00:00

abstract：:Chloroplast microsatellites for two Korean endemic species, Eranthis byunsanensis and E. pungdoensis (Ranunculaceae), were isolated to address the questions of their distributional patterns and evolutionary relationships, using next-generation sequencing. Twenty-four polymorphic chloroplast microsatellite markers for ...

journal_title：Molecular biology reports

authors： Oh A,Oh BU

更新日期：2017-08-01 00:00:00

abstract：:To determine whether methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms are associated with pre-eclampsia susceptibility. Literature searches of the Pubmed, Embase, BIOSIS Previews and Web of Science were conducted to identify all eligible articles up to January 18th, 2013. The pooled odds rati...

journal_title：Molecular biology reports

authors： Li X,Luo YL,Zhang QH,Mao C,Wang XW,Liu S,Chen Q

更新日期：2014-08-01 00:00:00

abstract：:The spleen plays a crucial role in innate and adaptive immunity in bony fish. Consequently, this organ is well suited to assess the immune competence of an organism and hence provides useful information for comparison and classification of production traits of food fish, such as robustness and susceptibility. To gain ...

journal_title：Molecular biology reports

authors： Köbis JM,Rebl A,Kühn C,Goldammer T

更新日期：2013-02-01 00:00:00

abstract：:Familial Mediterranean fever is an autosomal recessive disorder characterized by recurrent attacks of abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible for the disease. The objective of this study was to identify the frequency and distribution of 12 MEFV mutations in 153 Syrian patients and ...

journal_title：Molecular biology reports

authors： Jarjour RA

更新日期：2010-01-01 00:00:00

abstract：:One of the major limitations when attempting to obtain detailed biochemical, biophysical and immunological characterization of plant DNA mismatch repair proteins is their extremely low abundance in vivo under normal growth conditions. An initial analysis of PMS1 transcript level in various Arabidopsis thaliana tissues...

journal_title：Molecular biology reports

authors： Galles C,Gomez RL,Spampinato CP

更新日期：2011-02-01 00:00:00

abstract：:The binding characteristics of the interaction between 3-(2-cyanoethyl) cytosine (CECT) and human serum albumin (HSA) were investigated using fluorescence, UV absorption spectroscopic and molecular modeling techniques under simulative physiological conditions. The intrinsic fluorescence intensity of HSA was decreased ...

journal_title：Molecular biology reports

authors： Cui FL,Hui GQ,Huo RN,Qu GR

更新日期：2012-11-01 00:00:00

abstract：:Kawasaki disease (KD) is a multi-systemic vasculitis which preferentially affects infants and children. A single nucleotide polymorphism (rs28493229) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) was identified to be associated with the increased risk of KD; however, in more recent studies associations have b...

journal_title：Molecular biology reports

authors： Lou J,Xu S,Zou L,Zhong R,Zhang T,Sun Y,Lu X,Liu L,Li C,Wang L,Xiong G,Wang W,Gong F,Wu J

更新日期：2012-12-01 00:00:00

abstract：:A member of satellite repetitive DNA was isolated and sequenced from a saltwater fish Sillago japonica (Percoidei). This sequence consists of several oligo-dA/dT tracts and two inverted repeats which resemble each other. Dot blot hybridization analysis using a satellite DNA clone pSJ2 among the species in the suborder...

journal_title：Molecular biology reports

authors： Kato M,Yoshida M

更新日期：1995-01-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:Free cytoplasmic mRNPs were isolated from human placenta. An activity of RNase was associated with these particles but was mostly inhibited by a labile protein inhibitor. Both RNase and RNase inhibitor were extractable from mRNPs by 0.5 M KCl. The nature of the association of the RNase-RNase inhibitor complex with mRN...

journal_title：Molecular biology reports

authors： Gileadi O,Lorberboum H,de Groot N,Hochberg AA

更新日期：1984-01-01 00:00:00

abstract：:Low levels of coenzyme Q10 (CoQ10) have been reported in the circulation of patients with breast cancer, particularly in metastatic features. Our objective was to study the correlation between plasma levels of CoQ10 and the tumoral expression levels of AMPK, PFKFB3, VEGF, and VEGFR2. This study was a part of consecuti...

journal_title：Molecular biology reports

authors： Abdi S,Montazeri V,Garjani A,Shayanfar A,Pirouzpanah S

更新日期：2020-04-01 00:00:00

abstract：:The objective of present study was to screen the effect of methyl jasmonate (MJ) in lipopolysaccharide (LPS) induced in vivo and in vitro arthritis. Arthritis was induced in wistar rats by intraplantar administration of LPS (1 mg/Kg) and effect of MJ was screened in two doses (20, 40 mg/Kg, IP), indomethacin (30 mg/Kg...

journal_title：Molecular biology reports

authors： Gunjegaonkar SM,Shanmugarajan TS

更新日期：2019-02-01 00:00:00

abstract：:Killer cell immunoglobulin like receptor genes expressed by the natural killer cells and T cells of some subclasses are one of the very diversity and complex gene families on chromosome 19q13.4 which play key developmental role in the fight against viral infections, malignantly transformed cells and so on in the first...

journal_title：Molecular biology reports

authors： Wang HD,Jin XY,Guo YX,Zhang Q,Zhang YW,Wang X,Zhu BF

更新日期：2019-02-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00

abstract：:Human Wharton's jelly mesenchymal stem cells (hWJSCs) are multipotent stem cells that could be aggregated into 3D spherules. ITGA4 and ITGA5 genes encode α4 and α5 subunits of integrins, respectively. In this study, we analyzed expression levels of ITGA4 and ITGA5 gene mRNAs in undifferentiated and 3D spherules formin...

journal_title：Molecular biology reports

authors： Mostafavi-Pour Z,Ashrafi MR,Talaei-Khozani T

更新日期：2018-06-01 00:00:00

abstract：:Coactivator CBP (CREB-binding protein) has been implicated in the regulation of transcription for all signal transducer and activator of transcription factors (STATs); however, the mechanism remains unclear. Using yeast two-hybrid screening and immunoprecipitation techniques, we investigated the direct interaction of ...

journal_title：Molecular biology reports

authors： Zhang M,Fu Z,Tian D,Liu E,Dai J,Wang L

更新日期：2011-10-01 00:00:00

abstract：:This meta-analysis was performed to evaluate the relationships between promoter DNA methylation in tumor suppressor gene p16 and gastric carcinogenesis. The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library and CBM databases were searched for relevant articles published before November 1s...

journal_title：Molecular biology reports

authors： Wang HL,Zhou PY,Liu P,Zhang Y

更新日期：2014-07-01 00:00:00

abstract：:DNA-, RNA- and protein synthesis have been studied in Mycobacterium smegmatis cells infected with phage I3. The macromolecular synthesis continued until the end of latent period. Early RNA and protein synthesis were necessary prior to the commencement of DNA replication. The infecting phage DNA sedimented as larger th...

journal_title：Molecular biology reports

authors： Nagaraja V,Gopinathan KP

更新日期：1981-11-30 00:00:00

abstract：AIM:To study the function of the prodomain of ADAM17 (TACE) and to develop an approach for interfering with inflammation processes. METHOD:The expression plasmids of the TACE ectodomain (T1300), prodomain (T591), signal peptide and prodomain (T648), full length (T2472), and the turncated TACE without prodomain (T57-T1...

journal_title：Molecular biology reports

authors： Li X,Yan Y,Huang W,Yang Y,Wang H,Chang L

更新日期：2009-04-01 00:00:00

abstract：:FK-506 binding proteins (FKBPs) belong to the peptidyl-prolyl cis/trans isomerase superfamily (PPIases, EC: 5.2.1.8) which catalyzes the interconversion of peptidyl-prolyl bonds while they can also act on polypeptides, as folding helper enzymes. Here, we biochemically characterize two recombinant FKBPs, AvfkbA1 and Av...

journal_title：Molecular biology reports

authors： Dimou M,Zografou C,Venieraki A,Katinakis P

更新日期：2012-12-01 00:00:00

abstract：:Whole-exome sequencing (WES) is an ideal method for the diagnosis of autosomal recessive diseases. The aim of this study was to evaluate the diagnostic power of WES in patients with autosomal recessive inheritance and to determine the relationship between genotype and phenotype. Retrospective screenings of 24 patients...

journal_title：Molecular biology reports

authors： Elmas M,Yıldız H,Erdoğan M,Gogus B,Avcı K,Solak M

更新日期：2019-02-01 00:00:00

abstract：:Immense body of evidence indicates that dysfunction of immune system is implicated in the etiology of schizophrenia. The immune theory of schizophrenia is supported by alterations in cytokine profile in the brain and peripheral blood. Given the strong genetic background of schizophrenia, it might be assumed that aberr...

journal_title：Molecular biology reports

authors： Frydecka D,Misiak B,Beszlej JA,Karabon L,Pawlak-Adamska E,Tomkiewicz A,Partyka A,Jonkisz A,Kiejna A

更新日期：2013-10-01 00:00:00

abstract：:The aim of this study was to explore candidate single nucleotide polymorphisms (SNPs) and candidate mechanisms of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Two SLE genome-wide association studies (GWASs) datasets were included in this study. Meta-analysis was conducted using 737,984 SNPs in 1,5...

journal_title：Molecular biology reports

authors： Lee YH,Bae SC,Choi SJ,Ji JD,Song GG

更新日期：2012-12-01 00:00:00

abstract：:In clinical practice, most patients with non small cell lung cancer (NSCLC) who respond to tyrosine kinase inhibitors eventually progress because of an acquired resistance mutation, T790M, in epidermal growth factor receptor (EGFR). Thus, it is important to identify a new drug to reduce resistance. The aim of this stu...

journal_title：Molecular biology reports

authors： Zhu H,Cheng H,Ren Y,Liu ZG,Zhang YF,De Luo B

更新日期：2012-04-01 00:00:00

abstract：:This study is to explore the relationship between vascular endothelial growth factor (VEGF) and pathological changes in cryptorchidism by using murine model of intraperitoneal cryptorchidism with surgical operation. To investigate the relationship between the changes of VEGF expression and heat stress inducing germ ce...

journal_title：Molecular biology reports

authors： Gao P,Gao J,Dou X,Peng D,Zhang Y,Li H,Zhu T,Jiang H,Zhang X

更新日期：2020-05-01 00:00:00

abstract：:Tumor microenvironment (TME) crucially functions in tumor initiation and progression. Stroma-tumor interactions and cellular transdifferentiation are the prerequisite for tumor formation. Transforming growth factor-β (TGF-β), a major cytokine secreted by tumor-associated fibroblasts (TAFs) and cancer cells, is a cruci...

journal_title：Molecular biology reports

authors： Wang XL,Huang C

更新日期：2019-06-01 00:00:00

abstract：:The genes of E. coli are located on a circular chromosome of 4.6 million basepairs. This 1.6 mm long molecule is compressed into a nucleoid to fit inside the 1-2 microm cell in a functional format. To examine the role of DNA supercoiling as nucleoid compaction force we modulated the activity of DNA gyrase by electroni...

journal_title：Molecular biology reports

authors： Stuger R,Woldringh CL,van der Weijden CC,Vischer NO,Bakker BM,van Spanning RJ,Snoep JL,Westerhoff HV

更新日期：2002-01-01 00:00:00