Long-term ketamine abuse induces cystitis in rats by impairing the bladder epithelial barrier.

abstract：:Sensitivity to phenylthiocarbamide (PTC) has a bimodal distribution pattern and the genotype of the TAS2R38 gene, which is composed of combinations of three coding single nucleotide polymorphisms (SNPs), p.A49P (c.145G>C), p.V262A (c.785T>C) and p.I296 V (c.886A>G), determines the ability or inability to taste PTC. In...

journal_title：Molecular biology reports

authors： Sagong B,Bae JW,Rhyu MR,Kim UK,Ye MK

更新日期：2014-03-01 00:00:00

abstract：:In jasmonate biosynthetic pathway, allene oxide synthase (AOS, EC 4.2.1.92), which is a cytochrome P450 (CYP74A), catalyzes the first committed step. We herein cloned a novel cDNA from Lonicera japonica Thunb., named LjAOS (GenBank accession: DQ303120), which was homologous to other AOSs. Southern blot analysis reveal...

journal_title：Molecular biology reports

authors： Jiang K,Pi Y,Hou R,Zeng H,Huang Z,Zhang Z,Sun X,Tang K

更新日期：2009-03-01 00:00:00

abstract：:Of the only known two Lagoon populations of Irrawaddy dolphins (Orcaella) in the world, one is residing in the Chilika Lagoon in Orissa state, India. In addition to accidental deaths in gill net fishery and mechanized boat operations, there has been exploitation of the species for their oil. Extreme patchy distributio...

journal_title：Molecular biology reports

authors： Jayasankar P,Patel A,Khan M,Das P,Panda S

更新日期：2011-03-01 00:00:00

abstract：:Phosphomannose isomerase (PMI) is an enzyme that catalyses the first step of the L-galactose pathway for ascorbic acid (AsA) biosynthesis in plants. To clarify the physiological roles of PMI in AsA biosynthesis, the cDNA sequence of PMI was cloned from non-heading Chinese cabbage (Brassica campestris ssp. chinensis Ma...

journal_title：Molecular biology reports

authors： Wang X,Zhang S,Hu D,Zhao X,Li Y,Liu T,Wang J,Hou X,Li Y

更新日期：2014-01-01 00:00:00

abstract：:microRNAs are short, non-coding RNAs, that exert a posttranscriptional control on protein synthesis by mRNA interference. They are involved in normal and pathological embryologic development, as well as in adult life pathology, from myocardial infarction to cancer. There are several brain-specific species of microRNA,...

journal_title：Molecular biology reports

authors： Enciu AM,Popescu BO,Gheorghisan-Galateanu A

更新日期：2012-03-01 00:00:00

abstract：:Bacterial leaf streak (BLS) caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an important disease of rice, which is responsible for the economic losses worldwide. Functional investigation of differentially expressed protein genes (DEPGs) from rice (Oryza sativa L.) upon Xoc infection provides insight into the molec...

journal_title：Molecular biology reports

authors： Guo L,Guo C,Li M,Wang W,Luo C,Zhang Y,Chen L

更新日期：2014-01-01 00:00:00

abstract：:The immunity and health status of ornamental fish is an important aspect, as they are kept in a confined environment and various stressful conditions which lead to depletion of overall colourful appearance and mortality. The carotenoids can act as immunity boosters in captive aquarium system and may be supplemented in...

journal_title：Molecular biology reports

authors： Tripathy PS,Khatei A,Parhi J,Choudhury TG,Sahoo L,Mandal SC

更新日期：2019-12-01 00:00:00

abstract：:Uterine leiomyomas (UL) are prevalent benign tumors, especially among women of African ancestry. The disease also has genetic liability and is influenced by risk factors such as hormones and obesity. This study investigates the haplotypes of the Cytochrome P450 1B1 gene (CYP1B1) related to hormones and coiled-coil dom...

journal_title：Molecular biology reports

authors： Alleyne AT,Bideau VS

更新日期：2019-06-01 00:00:00

abstract：:Molecular DNA markers are used for detection of polymorphisms in individuals. As they are independent of developmental stage of the plant and environmental influences, they can be useful tools in taxonomy. The alleles of simple sequence repeat (SSR) markers (or microsatellites) are traditionally used to identify taxon...

journal_title：Molecular biology reports

authors： Tuler AC,Carrijo TT,Nóia LR,Ferreira A,Peixoto AL,da Silva Ferreira MF

更新日期：2015-11-01 00:00:00

abstract：:Apoptotic response in hepatocellular carcinoma (HCC) cells is impaired because of interconnectivity of proteins into complexes and signaling networks that are highly divergent in time and space. TNF-related apoptosis-inducing ligand (TRAIL) has emerged as an attractive anticancer agent reported to selectively induce a...

journal_title：Molecular biology reports

authors： Fayyaz S,Yaylim I,Turan S,Kanwal S,Farooqi AA

更新日期：2014-10-01 00:00:00

abstract：:Drought is one of the major abiotic stresses that affect productivity in soybean (Glycine max L.) Several genes induced by drought stress include functional genes and regulatory transcription factors. The Arabidopsis thaliana DREB1D transcription factor driven by the constitutive and ABA-inducible promoters was introd...

journal_title：Molecular biology reports

authors： Guttikonda SK,Valliyodan B,Neelakandan AK,Tran LS,Kumar R,Quach TN,Voothuluru P,Gutierrez-Gonzalez JJ,Aldrich DL,Pallardy SG,Sharp RE,Ho TH,Nguyen HT

更新日期：2014-12-01 00:00:00

abstract：:The objective of present study was to screen the effect of methyl jasmonate (MJ) in lipopolysaccharide (LPS) induced in vivo and in vitro arthritis. Arthritis was induced in wistar rats by intraplantar administration of LPS (1 mg/Kg) and effect of MJ was screened in two doses (20, 40 mg/Kg, IP), indomethacin (30 mg/Kg...

journal_title：Molecular biology reports

authors： Gunjegaonkar SM,Shanmugarajan TS

更新日期：2019-02-01 00:00:00

abstract：:Potato (Solanum tubersosum L.) is relatively vulnerable to abiotic stress conditions such as drought, but the tolerance mechanisms to such stress in potato are largely unknown. To gain insight into the transcriptome dynamics that are associated with drought stress, genome-wide gene expression profile was conducted by ...

journal_title：Molecular biology reports

authors： Zhang N,Liu B,Ma C,Zhang G,Chang J,Si H,Wang D

更新日期：2014-01-01 00:00:00

abstract：:The objective of this study was to determine hepatic expression levels of GHR, IGF1R, IGF1 and IGF2 genes in young growing gilts at different developmental ages (60-210 days) in five pig breeds: Polish Large White (PLW), Polish Landrace (PL), Pulawska (Pul), Duroc (Dur) and Pietrain (Pie). We studied the differences a...

journal_title：Molecular biology reports

authors： Pierzchała M,Pareek CS,Urbański P,Goluch D,Kamyczek M,Różycki M,Smoczynski R,Horbańczuk JO,Kurył J

更新日期：2012-03-01 00:00:00

abstract：:As-NUPR1, a stress-related protein, plays an important role in post-diapause during embryonic development in the brine shrimp Artemia sinica. In the present study, successful expression of As-NUPR1 from the cDNA sequence isolated from A. sinica was demonstrated using a prokaryotic expression system. The recombinant pr...

journal_title：Molecular biology reports

authors： Zhang R,Yao F,Cheng C,Chen Y,Lv Y,Li Z,Zhao N,Wang T,Xin W,Zou X,Hou L

更新日期：2014-05-01 00:00:00

abstract：:Staudtia kamerunensis (Myristicaceae) or 'Niové' is an evergreen tree widespread in Central African moist forests. The bark and seeds are used in traditional medicine, yet the tree is mainly harvested for its high quality, multi-purpose timber. To facilitate sustainable harvesting and conservation of the species, we a...

journal_title：Molecular biology reports

authors： Vanden Abeele S,Hardy OJ,Janssens SB

更新日期：2018-10-01 00:00:00

abstract：:Alterations in expression of the DFF40 gene have been reported in some cancers. This study is an in vitro study of the therapeutic effects of gene transfer that lead to elevation in DFF40 expression within T-47D cells in the presence of sulfonamide drugs. In this study, we have constructed a eukaryotic expression vect...

journal_title：Molecular biology reports

authors： Bagheri F,Safarian S,Eslaminejad MB,Sheibani N

更新日期：2014-11-01 00:00:00

abstract：:Based on the internal transcribed spacer and inter-simple sequence repeats (ISSR), the phylogenetic relationship and genetic diversity of Metarhizium spp., pathogens found in Chinese burrower bugs, Schiodtella formosana, were analyzed. The results showed that the causative agents of the epizootic green muscardine dise...

journal_title：Molecular biology reports

authors： Luan F,Zhang S,Wang B,Huang B,Li Z

更新日期：2013-01-01 00:00:00

abstract：:Safe harbor loci allow predicable integration of a transgene into the genome without perturbing endogenous gene activity and for decades have been exploited in the mouse to investigate gene function, generate humanised models and create tissue specific reporter and Cre recombinase expressing lines. Herein, we show tha...

journal_title：Molecular biology reports

authors： Browning J,Rooney M,Hams E,Takahashi S,Mizuno S,Sugiyama F,Fallon PG,Kelly VP

更新日期：2020-02-01 00:00:00

abstract：:The lysyl oxidase-like 2 (LOXL2) protein is a human paralogue of lysyl oxidase (LOX) that functions as an amine oxidase for formation of lysine-derived cross-links found in collagen and elastin. In addition to the C-terminal domains characteristic to the LOX family members, LOXL2 contains four scavenger receptor cyste...

journal_title：Molecular biology reports

authors： Kim YM,Kim EC,Kim Y

更新日期：2011-01-01 00:00:00

abstract：:The antibacterial and anticancerous properties of EMTAHDCA have already been reported in our previous study. However, mode of action of EMTAHDCA is still elusive. The present study was aimed to investigate the molecular targets in Escherichia coli and spleen of lymphoma-bearing mice in response to cyanocompound 9-ethy...

journal_title：Molecular biology reports

authors： Niveshika,Maurya SK,Tiwari B,Chakraborty S,Verma E,Mishra R,Mishra AK

更新日期：2019-06-01 00:00:00

abstract：:The Rv3203 (LipV) of Mycobacterium tuberculosis (Mtb) H37Rv, is annotated as a member of Lip family based on the presence of characteristic consensus esterase motif ‘GXSXG’. In vitro culture studies of Mtb H37Ra indicated that expression of Rv3203 gene was up-regulated during acidic stress as compared to normal wherea...

journal_title：Molecular biology reports

authors： Singh G,Arya S,Narang D,Jadeja D,Singh G,Gupta UD,Singh K,Kaur J

更新日期：2014-01-01 00:00:00

abstract：:Adenylosuccinate lyase (ADSL) is a bifunctional enzyme acting in de novo purine synthesis and purine nucleotide recycling. In the present study, we have constructed a grass carp (Ctenopharyngodon idella) intestinal cDNA library that has over 2.3 × 10(5) primary clones. An expressed sequence tag (EST) of grass carp ade...

journal_title：Molecular biology reports

authors： Yuan T,Gu JR,Gu WB,Wu J,Ge SR,Xu H

更新日期：2011-03-01 00:00:00

abstract：:The purpose was to analyze the growth hormone GH1/GH2-N and GH2-Z gene copies and to assess their possible association with milk traits in Sarda sheep. Two hundred multiparous lactating ewes were monitored. The two gene copies were amplified separately and each was used as template for a nested PCR, to investigate sin...

journal_title：Molecular biology reports

authors： Vacca GM,Dettori ML,Balia F,Luridiana S,Mura MC,Carcangiu V,Pazzola M

更新日期：2013-09-01 00:00:00

abstract：:The small molecules already existing on the earth can be assembled to biological macromolecules in the presence of the suitable tool. A workman must sharpen his tools if he is to do his work well. The tool must be specific, delicate and automatic. Obviously, it is enzyme. Therefore, to explore the origin of life we mu...

journal_title：Molecular biology reports

authors： Yin X,Yuan Z

更新日期：2009-02-01 00:00:00

abstract：:Calcific mitral valve stenosis (MVS) is a common disease characterized by extensive remodeling of the extracellular matrix via matrix metalloproteinases (MMPs). The mechanism of calcification due to extensive matrix remodeling remains unclear. In this study, we investigated the relationship between MMP-3, tissue inhib...

journal_title：Molecular biology reports

authors： Aloui S,Zidi W,Ouali S,Guizani I,Hadj-Taieb S,Mourali MS,Feki M,Allal-Elasmi M

更新日期：2018-12-01 00:00:00

abstract：:Synthetic hexaploid (SH) wheat derived from crossing tetraploid durum wheat and diploid Aegilops tauschii provide germplasm for wheat improvement as the conventional wheat varieties possess very low genetic diversity. This study aims to identify diverse SH lines which can be used in breeding programs for transferring ...

journal_title：Molecular biology reports

authors： Shakeel M,Ilyas M,Kazi M

更新日期：2013-01-01 00:00:00

abstract：:The big advantage of using molecular biomarkers to monitor oxygen levels in aquatic systems is that responses at the molecular level tend to be more sensitive, and usually occur earlier than those at higher levels of biological organization Aquatic hypoxia is a frequent event, which can occur naturally in a variety of...

journal_title：Molecular biology reports

authors： Rimoldi S,Terova G,Ceccuzzi P,Marelli S,Antonini M,Saroglia M

更新日期：2012-04-01 00:00:00

abstract：:Overexpression of differentiated embryo chondrocyte 1 (DEC1) has been reported to contribute to the cellular differentiation, proliferation, and apoptosis of various cancers. Our previous studies have shown that DEC1 was highly expressed in gastric cancer (GCa) tissues. However, there is no report about the expression...

journal_title：Molecular biology reports

authors： Zheng Y,Shi X,Wang M,Jia Y,Li B,Zhang Y,Liu Q,Wang Y

更新日期：2012-04-01 00:00:00

abstract：:Expression of recombinant proteins is a standard technique in molecular biology and a wide variety of prokaryotic as well as eukaryotic expression systems are currently in use. A limiting step is often the purification of the expressed recombinant protein, particularly if mammalian expression systems that yield low ex...

journal_title：Molecular biology reports

authors： Schmitt J,Hess H,Stunnenberg HG

更新日期：1993-10-01 00:00:00