Profiling methyl-CpG specific determinants on transcriptionally silent chromatin.

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Sheep are valuable resources for the wool industry. Wool growth of Aohan fine wool sheep has cycled during different seasons in 1 year. Therefore, identifying genes that control wool growth cycling might lead to ways for improving the quality and yield of fine wool. In this study, we employed Agilent sheep gene expres...

journal_title：Molecular biology reports

authors： Liu N,Li H,Liu K,Yu J,Cheng M,De W,Liu J,Shi S,He Y,Zhao J

更新日期：2014-08-01 00:00:00

abstract：:Nuclear magnetic resonance (NMR) spectroscopy is a useful biophysical technique to study the ligand-protein interaction. In this report, we have used bacterially produced ERβ and its domains for studying the functional analysis of ligand-protein interaction. Briefly, ERβ and its transactivation domain (TAD) and ligand...

journal_title：Molecular biology reports

authors： Paramanik V,Thakur MK

更新日期：2011-10-01 00:00:00

abstract：:Narrow-leafed lupin (Lupinus angustifolius L.) is used as grain legumes, fodder for livestock and green manure in the world and has a great potential to be developed as a new crop in China. In this study, we assessed the genetic diversity among a set of 109 newly introduced accessions of narrow-leafed lupin using 76 g...

journal_title：Molecular biology reports

authors： Ji Y,Liu R,Hu J,Huang Y,Wang D,Li G,Rahman MM,Zhang H,Wang C,Li M,Yang T,Zong X

更新日期：2020-07-01 00:00:00

abstract：:Mitochondrial disorders are a frequent cause of neurological disability affecting children and adults. Traditionally, molecular diagnosis of mitochondrial diseases was mostly accomplished by the use of Sanger sequencing and PCR-RFLP. However, there are particular drawbacks associated with the use of these methods. Rec...

journal_title：Molecular biology reports

authors： Kauffman MA,Gonzlez-Morón D,Consalvo D,Westergaard G,Vazquez M,Mancini E,Taratuto AL,Rey R,Kochen S

更新日期：2012-06-01 00:00:00

abstract：:PaeI, a new restriction endonuclease from Pseudomonas aeruginosa clinical strain was isolated and characterized. It recognizes and cleaves the sequence 5'-GCATG reduced C-3' generating DNA fragments with 3'-tetranucleotide sticky ends. DNAs of pBR322, SV40 and bacteriophage lambda have one, two and six PaeI recognitio...

journal_title：Molecular biology reports

authors： Sokolov NN,Fitsner AB,Anikeitcheva NV,Choroshoutina YuB,Samko OT,Kolosha VO,Fodor I,Votrin II

更新日期：1985-04-01 00:00:00

abstract：:The rapid progress made over the last 10 years in the identification of individual autoantigens and in the localization of the epitopes involved, has resulted in a parallel reduction in the complexity of the antigen required for the detection of autoantibodies. The ability to use synthetic peptides as antigens is a re...

journal_title：Molecular biology reports

authors： Elkon KB

更新日期：1992-06-01 00:00:00

abstract：:The human COX-2 promoter contains a direct repeat 1 (DR1) which was shown to confer responsiveness to PPARs. We found that in AN(3)CA and F9 cells, this hCOX-2 DR1 mediates responsiveness to all-trans-retinoic acid (tRA) or 9-cis-retinoic acid (9cRA), but this effect was suppressed by PPARδ. Truncated PPARδ lacking th...

journal_title：Molecular biology reports

authors： Han K,Moon I,Lim HJ

更新日期：2011-02-01 00:00:00

abstract：:Telomerase activity is repressed in normal human somatic cells, but is activated in most cancers, suggesting that telomerase may be an important target for cancer therapy. Agents that interact selectively with telomerase are anticipated to exert specific action on cancer cells. In this study, we evaluated maleimide de...

journal_title：Molecular biology reports

authors： Huang PR,Yeh YM,Pao CC,Chen CY,Wang TC

更新日期：2012-09-01 00:00:00

abstract：:The oligochaete earthworm, Eudrilus eugeniae is capable of regenerating both anterior and posterior segments. The present study focuses on the transcriptome analysis of earthworm E. eugeniae to identify and functionally annotate the key genes supporting the anterior blastema formation and regulating the anterior regen...

journal_title：Molecular biology reports

authors： Paul S,Balakrishnan S,Arumugaperumal A,Lathakumari S,Syamala SS,Arumugaswami V,Sivasubramaniam S

更新日期：2020-12-11 00:00:00

abstract：:Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs24...

journal_title：Molecular biology reports

authors： Sun R,Huang Y,Zhang H,Liu R

更新日期：2013-11-01 00:00:00

abstract：:The Great-billed Seed-finch, Sporophila maximiliani, is a threatened neotropical bird that has declined mainly due to illegal trapping, with very few records in the wild in the last two decades. Despite the existence of a considerable captive population that could be used for reintroductions into the wild, many indivi...

journal_title：Molecular biology reports

authors： Medolago CAB,Costa MC,Ubaid FK,Glenn TC,Silveira LF,Francisco MR

更新日期：2018-12-01 00:00:00

abstract：:Neuroinflammation affects millions of people around the world as a result of injury or stress. Neuroinflammation represents almost all types of neurological diseases such as multiple sclerosis and Alzheimer's disease. Neurodegenerative diseases comprise demyelination and synaptic loss. The inflammatory response is fur...

journal_title：Molecular biology reports

authors： Siddiqui S,Kamal A,Khan F,Jamali KS,Saify ZS

更新日期：2019-02-01 00:00:00

abstract：:Coactivator CBP (CREB-binding protein) has been implicated in the regulation of transcription for all signal transducer and activator of transcription factors (STATs); however, the mechanism remains unclear. Using yeast two-hybrid screening and immunoprecipitation techniques, we investigated the direct interaction of ...

journal_title：Molecular biology reports

authors： Zhang M,Fu Z,Tian D,Liu E,Dai J,Wang L

更新日期：2011-10-01 00:00:00

abstract：:Previous data on association between CYP2E1 Rsa I/Pst I polymorphism and oral cancer risk were controversial. To investigate the association between CYP2E1 Rsa I/Pst I polymorphism and oral cancer risk. We performed a meta-analysis to assess the relationship between oral cancer and genotype with English language until...

journal_title：Molecular biology reports

authors： Niu Y,Hu Y,Wu M,Jiang F,Shen M,Tang C,Chen N

更新日期：2012-01-01 00:00:00

abstract：:Cellular cholesterol homeostasis is controlled by the sterol-regulatory element binding transcription factors (SREBFs) that are activated by an SREBF cleavage-activating protein (SCAP). SREBF-2 1784G > C single nucleotide polymorphism (SNP, rs2228314) and SCAP 2386A > G variant (rs12487736) are associated with early o...

journal_title：Molecular biology reports

authors： Chen Z,Ding Z,Ma G,Liu N,Qian Q

更新日期：2011-06-01 00:00:00

abstract：:We examined genetic associations of previously identified sequence variants with bone mineral density and their heterogeneity by gender. Large-scale cohort data were used including a total of 8,419 subjects (4,034 males and 4,385 females) from the Korean Association REsource (KARE) cohort. Bone speed of sound (SOS) va...

journal_title：Molecular biology reports

authors： Woo J,Kim Y,Lee C

更新日期：2012-03-01 00:00:00

abstract：:Long terminal repeat (LTR)-retrotransposons are mobile genetic elements that are ubiquitous in plants and constitute a major portion of their nuclear genomes. LTR- retrotransposons possess unique properties that make them appropriate for investigating relationships between populations, varieties and closely related sp...

journal_title：Molecular biology reports

authors： Woodrow P,Pontecorvo G,Ciarmiello LF

更新日期：2012-04-01 00:00:00

abstract：:Proteasomes (prosomes) are large multiprotein complexes. They are involved in protein degradation of ubiquitin-conjugated proteins and in the generation of MHC class I peptides. We gave further evidence that they interfere with in vitro protein synthesis. Proteasomes inhibit the translation of Tobacco mosaic virus RNA...

journal_title：Molecular biology reports

authors： Homma S,Horsch A,Pouch MN,Petit F,Briand Y,Schmid HP

更新日期：1994-01-01 00:00:00

abstract：:STAT4 is a transcription factor that has been implicated in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Recently, several reports has documented that a STAT4 haplotype is associated with RA, SLE and Sjogren's syndrome. To summarize and review these findings, we conducted a met...

journal_title：Molecular biology reports

authors： Ji JD,Lee WJ,Kong KA,Woo JH,Choi SJ,Lee YH,Song GG

更新日期：2010-01-01 00:00:00

abstract：:The freshwater true bug Aphelocheirus aestivalis (Aphelocheiridae) is widely distributed in Europe but occurs rather locally and often in isolated populations. Moreover, it is threatened with extinction in parts of its range. Unfortunately, little is known about the genetic diversity and population structure due to th...

journal_title：Molecular biology reports

authors： Kaczmarczyk-Ziemba A

更新日期：2020-12-01 00:00:00

abstract：:The aim of this study was to determine whether the Fcγ receptors (FCGRs) polymorphisms confer susceptibility to periodontitis in ethnically different populations. We did a literature search using PubMed and Embase, and conducted a meta-analysis on the associations between the FCGR2A H131R (rs1801274), FCGR3A F158V (rs...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:An improvement in the detection by nucleic acid hybridization of size-fractionated RNA immobilized to nylon-based membranes is described. Electrophoretic transfer of RNA to nylon membranes permits a quantitative determination of different RNA transcripts on the same membrane after sequential hybridization using differ...

journal_title：Molecular biology reports

authors： Khandjian EW

更新日期：1986-01-01 00:00:00

abstract：:A secretory high-level expression cloning vector designated as pSBC-20 was constructed by inserting a DNA fragment encoding the signal peptide of ompA protein into pBV 220 vector. Any foreign DNA fragment can be inserted into the polylinker cloning sites located after the secretion signal sequence. The cloned foreign ...

journal_title：Molecular biology reports

authors： Li Y,Yan YC,Guo W,Zhao F,Lai J,Koide SS

更新日期：1995-01-01 00:00:00

abstract：:The oriental melon (Cucumis melo var. makuwa), called 'chamoe' in Korean, is a popular fruit crop cultivated mainly in Asia and a high-market value crop in Korea. To provide molecular breeding resources for chamoe, we developed and characterized genomic SSR markers from the preliminary Illumina read assemblies of Gotg...

journal_title：Molecular biology reports

authors： Park I,Kim J,Lee J,Kim S,Cho O,Yang K,Ahn J,Nahm S,Kim H

更新日期：2013-12-01 00:00:00

abstract：:Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence, this study evaluated the cardioprotective mechanism(s) of Morin against isoproterenol induced myocardial necrosis in rats. Male albino Wistar rats were divided ...

journal_title：Molecular biology reports

authors： Verma VK,Malik S,Narayanan SP,Mutneja E,Sahu AK,Bhatia J,Arya DS

更新日期：2019-02-01 00:00:00

abstract：:The study was done to identify the candidate causal single nucleotide polymorphisms (SNPs) and candidate causal mechanisms that contribute to Parkinson's disease (PD) susceptibility and to generate a SNP to ene to pathway hypothesis using an analytical pathway-based approach. We used a PD genome-wide association study...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-03-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERP...

journal_title：Molecular biology reports

authors： An L,Yang T,Zhang Y,Lin Y,Zhang H,Jiao X,Hua L,Dai H,Wang C

更新日期：2012-02-01 00:00:00

abstract：:Cerebral aneurysm affects 2-5% of the population and posterior inferior cerebellar artery (PICA) aneurysms account for 1-3% of all intracranial aneurysms. Oxidative stress is known to contribute to the progression of cerebrovascular disease and it may be increased by inflammation, a key contributor to cerebral aneurys...

journal_title：Molecular biology reports

authors： Šćepanović V,Tasić G,Repac N,Nikolić I,Janićijević A,Todorović D,Stojanović M,Šćepanović R,Mitrović D,Šćepanović T,Borozan S,Šćepanović L

更新日期：2018-12-01 00:00:00

abstract：:A double-stranded RNA-specific nuclease (ds RNase) has been isolated and partially purified from human placenta by DEAE-cellulose and DNA-cellulose column chromatography. Denatured DNA-cellulose retained most of the single-stranded RNA-specific nuclease (ss RNase) activity, whereas the ds RNase came out in the void vo...

journal_title：Molecular biology reports

authors： Kalyanaraman S,Maran A,Shanmugam G

更新日期：1983-08-01 00:00:00