Dissociability of free and peptidyl-tRNA bound ribosomes.

abstract：:Free cytoplasmic 40S mRNP particles from rat liver were treated with EDTA and separated into two populations of RNP particles with sedimentation maxima of 20S and 35S, respectively. A characteristic set of distinct scRNAs is found for 20S and 35S RNP particles. The sequences of two of the most abundant scRNAs from 20S...

journal_title：Molecular biology reports

authors： Villringer A,Kühn B,Schneider K,Andus T,Michels K,Northemann W,Krupp G,Walckhof B,Gross HJ,Klump H,Kroll A,Branlant C,Heinrich PC

更新日期：1983-05-01 00:00:00

abstract：:Quercus acutissima is native to eastern Asia. It has a wide distribution in China and China is an important component in understanding the ecology and genetic structure of this species. Q. acutissima attained high economic value for hardwood product and can be managed as an energy tree species. To investigate the gene...

journal_title：Molecular biology reports

authors： Zhang YY,Fang YM,Yu MK,Li XX,Xia T

更新日期：2013-06-01 00:00:00

abstract：:Recent studies suggest that the common variant in the GSTM1 and GSTT1 genes modifies the risk of coronary artery disease (CAD), however, it is unclear whether the risk of CAD modulated by variants in the GSTM1 and GSTT1 genes was associated with alterations of indices of oxidative stress and inflammation. Our study is...

journal_title：Molecular biology reports

authors： Tang JJ,Wang MW,Jia EZ,Yan JJ,Wang QM,Zhu J,Yang ZJ,Lu X,Wang LS

更新日期：2010-01-01 00:00:00

abstract：:Phage display procedure was applied to the N-terminal domain of human topoisomerase I. The consensus sequence identified for clones binding to the N-terminal domain was found in 35 human proteins that are either permanently or temporarily located in the nucleus. They are in majority involved in the DNA repair, transcr...

journal_title：Molecular biology reports

authors： Trzcińska AM,Girstun A,Piekiełko A,Kowalska-Loth B,Staroń K

更新日期：2002-12-01 00:00:00

abstract：:Adipose differentiation-related protein gene (ADP) plays an important role in controlling lipid accumulation in mammals. It may also affect lipid deposition in birds. However, the molecular mechanism of its actions in birds remains unknown. In the present study, the coding sequence of ADP cDNA for Chinese native breed...

journal_title：Molecular biology reports

authors： Zhao X,Zhu Q,Wang Y,Yang Z,Liu Y

更新日期：2010-07-01 00:00:00

abstract：:Schizophrenia is a chronic and neuropsychiatric disease that affects about 0.5-1% of the world's population. An increase in dopamine and dopamine D2 receptor (DRD2) gene products has been well described in schizophrenic patients. Several groups have studied the relationship between dopaminergic hyperactivity and cellu...

journal_title：Molecular biology reports

authors： Kurt H,Dikmen M,Basaran A,Yenilmez C,Ozdemir F,Degirmenci I,Gunes HV,Kucuk MU,Mutlu F

更新日期：2011-02-01 00:00:00

abstract：:The Cichlid fish Sarotherodon melanotheron is typically found in West and Central African estuaries and lagoons. It represents a good candidate for promoting tilapia farming in brackish waters. Understanding the genetic diversity in its populations from the hydrographical basins of Southern Benin is primordial before ...

journal_title：Molecular biology reports

authors： Amoussou TO,Youssao Abdou Karim I,Dayo GK,Imorou Toko I,Séré M,Chikou A,Toguyéni A

更新日期：2018-12-01 00:00:00

abstract：:The Follicle stimulating hormone beta polypeptide (FSHβ) gene has been investigated as a candidate gene for litter size because of its role in maturation of small and medium follicles into ovulating large follicles. Genes coding follicle stimulating hormone have been found to have significant effects on litter size in...

journal_title：Molecular biology reports

authors： Magotra A,Naskar S,Das B,Ahmad T

更新日期：2015-02-01 00:00:00

abstract：:Human Papillomavirus infection is considered as the main etiological factor of cervical cancer (ICC), although, the role of host genetic factors in ICC susceptibility has been increasing. Immunological response is crucial for the prevention of viral associated diseases. Interleukin 1 receptor antagonist (IL-1RN) is co...

journal_title：Molecular biology reports

authors： Sousa H,Santos AM,Catarino R,Pinto D,Moutinho J,Canedo P,Machado JC,Medeiros R

更新日期：2012-12-01 00:00:00

abstract：:The antibacterial and anticancerous properties of EMTAHDCA have already been reported in our previous study. However, mode of action of EMTAHDCA is still elusive. The present study was aimed to investigate the molecular targets in Escherichia coli and spleen of lymphoma-bearing mice in response to cyanocompound 9-ethy...

journal_title：Molecular biology reports

authors： Niveshika,Maurya SK,Tiwari B,Chakraborty S,Verma E,Mishra R,Mishra AK

更新日期：2019-06-01 00:00:00

abstract：:The majority of the genomic DNA sequence in mammalian and other higher organisms can be transcribed into abundant functional RNA transcripts, especially regulatory non-coding RNAs (ncRNAs) that are expressed in a developmentally and species-specific regulated manner. Here, we review various regulatory non-coding RNAs,...

journal_title：Molecular biology reports

authors： Huang B,Zhang R

更新日期：2014-06-01 00:00:00

abstract：:Immense body of evidence indicates that dysfunction of immune system is implicated in the etiology of schizophrenia. The immune theory of schizophrenia is supported by alterations in cytokine profile in the brain and peripheral blood. Given the strong genetic background of schizophrenia, it might be assumed that aberr...

journal_title：Molecular biology reports

authors： Frydecka D,Misiak B,Beszlej JA,Karabon L,Pawlak-Adamska E,Tomkiewicz A,Partyka A,Jonkisz A,Kiejna A

更新日期：2013-10-01 00:00:00

abstract：:Familial Mediterranean fever is an autosomal recessive disorder characterized by recurrent attacks of abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible for the disease. The objective of this study was to identify the frequency and distribution of 12 MEFV mutations in 153 Syrian patients and ...

journal_title：Molecular biology reports

authors： Jarjour RA

更新日期：2010-01-01 00:00:00

abstract：:Growth-regulating factor (GRF) is an important protein in GA-mediated response, with key roles in plant growth and development. However, it is not known whether or how the GRF proteins in citrus to regulate organ size. In this study, nine citrus GRF genes (CsGRF1-9) were validated from the 'Anliu' sweet orange (AL, Ci...

journal_title：Molecular biology reports

authors： Liu X,Guo LX,Jin LF,Liu YZ,Liu T,Fan YH,Peng SA

更新日期：2016-10-01 00:00:00

abstract：:In this study we are presenting the development of technetium-99m (99mTc) labeled ibuprofen for the imaging of aseptic inflammation. 99mTc-Ibuprofen complex was developed by optimizing the radiolabeling conditions such as reaction time, ligand and reducing agent concentration, pH, reaction time and temperature. Follow...

journal_title：Molecular biology reports

authors： Khan NU,Naqvi SAR,Sohail H,Roohi S,Jamal MA

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this research is to identify the probable mitochondrial factor associated with cytoplasmic male sterility (cms) by comparative analysis of cms and its isogenic maintainer lines in stem mustards. Dramatic variations in the morphology of floral organs were observed in cms stem mustard. Mitochondrial atpA ...

journal_title：Molecular biology reports

authors： Yang JH,Huai Y,Zhang MF

更新日期：2009-02-01 00:00:00

abstract：:The blue swimming crab (Portunus pelagicus) is a valuable marine fishery resource in Indo-West Pacific Ocean. So far, rare genetic resource of this species is available. In this report, the restriction-site associated DNA (RAD) approach was employed to mine the genomic information and identify molecular markers in P. ...

journal_title：Molecular biology reports

authors： Wu Q,Miao G,Li X,Liu W,Ikhwanuddin M,Ma H

更新日期：2018-12-01 00:00:00

abstract：:As initial steps to define how the 26S proteasome degrades ubiquitinated proteins in plants, we have characterized many of the subunits that comprise the proteolytic complex from Arabidopsis thaliana. A set of 23 Arabidopsis genes encoding the full complement of core particle (CP) subunits and a collection encoding 12...

journal_title：Molecular biology reports

authors： Fu H,Girod PA,Doelling JH,van Nocker S,Hochstrasser M,Finley D,Vierstra RD

更新日期：1999-04-01 00:00:00

abstract：:Tall fescue is a perennial cool-season grass with economic importance especially in temperate regions of the northern hemisphere. This study was done to assess the genetic diversity and population structure of 90 tall fescue populations and cultivars using ISSR and EST-SSR markers in order to categorize valuable popul...

journal_title：Molecular biology reports

authors： Shahabzadeh Z,Mohammadi R,Darvishzadeh R,Jaffari M

更新日期：2020-01-01 00:00:00

abstract：:Several lines of evidence suggest that the ubiquitin-proteasome pathway is involved in sepsis-induced muscle catabolism. The gene expression of ubiquitin and several of the proteasome subunits was increased in muscle from both septic rats and patients. In other studies, the activity of isolated 20S proteasomes was sti...

journal_title：Molecular biology reports

authors： Hasselgren PO

更新日期：1999-04-01 00:00:00

abstract：:Using kinetics of approach to steady state labeling, we have found that liver poly(A)+ mRNAs fall into three populations, differing in stability and probably in processing, as reflected in their dissimilar delays in reaching polyribosomes and turnover times. There are mRNA-1 (delay 10 min, half-life 1 hr); mRNA-2(dela...

journal_title：Molecular biology reports

authors： Lubimova EV,Chernovskaja TV,Lerman MI

更新日期：1975-12-01 00:00:00

abstract：:ERBB2/HER2/NEU, a member of the epidermal growth factor receptor family, is overexpressed in more than 25 % of non-small cell lung cancer and is considered to be a significant and independent prognostic factor in lung cancer. Here we generated a lung specific HER2 overexpressing transgenic mouse model. In this model, ...

journal_title：Molecular biology reports

authors： Zeng S,Yang Y,Tan Y,Lu C,Pan Y,Chen L,Lu G

更新日期：2012-08-01 00:00:00

abstract：:Salvia lachnostachys is an herbaceous plant with anti-inflammatory, analgesic and cytotoxic properties. This study investigated the antitumor effect of an ethanolic extract of Salvia lachnostachys leaves (EES) in a solid Ehrlich carcinoma model. Ehrlich cells were inoculated subcutaneously in the right pelvic member (...

journal_title：Molecular biology reports

authors： Corso CR,Stipp MC,Adami ER,da Silva LM,Mariott M,de Andrade SF,de Souza Ramos EA,Klassen G,Beltrame OC,Queiroz-Telles JE,de Oliveira CS,Stefanello MÉA,Acco A

更新日期：2019-10-01 00:00:00

abstract：:Inhibitor of growth protein 3 (ING3), a new member of ING family, is involved in the regulation of various processes. In this study, a full-length cDNA of ING3 (named as RpING3) was cloned from the gill of Ruditapes philippinarum by rapid amplification of cDNA ends method for the first time. The cDNA obtained was 1442...

journal_title：Molecular biology reports

authors： Hu GW,Yan XW,Qin YJ,Nie HT

更新日期：2014-06-01 00:00:00

abstract：:Cell free protein synthesis has become a powerful method for the high-throughput production of proteins that are difficult to express in living cells. The protein SAP2 of Fasciola hepatica (FhSAP2), which has demonstrated to be both, an excellent vaccine candidate against experimental fascioliasis and a good antigen f...

journal_title：Molecular biology reports

authors： Ramos-Benítez MJ,Lopez-Cruz LM,Aguayo V,Ruiz-Jimenez C,Espino AM

更新日期：2018-10-01 00:00:00

abstract：:MAPK kinase 1 interacting protein 1 (MAP2K1ip1) is an important scaffold proteins of the mitogen-activated protein kinase (MAPK) pathway that form an active signaling module and enhance the specificity and spatiality of MAPK signaling. In the present study, we identified and characterized a MAP2K1ip1 cDNA from tiger s...

journal_title：Molecular biology reports

authors： Yang L,Liu X,Huang J,Yang Q,Qiu L,Liu W,Jiang S

更新日期：2012-05-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a world-wide health problem and its incidence accounts for 1.9-3.5% of all malignant tumors. Transforming growth factor beta/Smads (TGF-beta/Smads) signaling pathway plays an important role in oncogenesis, but its function and molecular mechanisms in OSCC remain unclear. Expressi...

journal_title：Molecular biology reports

authors： Wang X,Sun W,Bai J,Ma L,Yu Y,Geng J,Qi J,Shi Z,Fu S

更新日期：2009-05-01 00:00:00

abstract：:Regulation of the sumoylation system at the level of gene expression has not yet been explored. To begin to define transcriptional regulatory features, the promoter region for the SUMO1 gene was cloned from human genomic DNA and characterized. Initially, a 532 base pair fragment upstream of and including the predicted...

journal_title：Molecular biology reports

authors： Nanos-Webb A,Deyrieux A,Bian XL,Rosas-Acosta G,Wilson VG

更新日期：2010-03-01 00:00:00

abstract：:Long non-coding RNAs (LncRNAs) are non-coding RNAs. The potential roles of lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to assess the expression levels of LY86-AS1 and HCG27_201 in T2DM patients and a healthy control group. We obtained whole blood and serum samples from 100 T2DM...

journal_title：Molecular biology reports

authors： Saeidi L,Ghaedi H,Sadatamini M,Vahabpour R,Rahimipour A,Shanaki M,Mansoori Z,Kazerouni F

更新日期：2018-12-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the main cause of blindness among the people in productive age. The purpose of this literature review is to highlight recent achievements in the genetics of diabetic retinopathy with particular focus on candidate gene studies. We...

journal_title：Molecular biology reports

authors： Priščáková P,Minárik G,Repiská V

更新日期：2016-12-01 00:00:00