Identification, characterization, and expression analysis of a serotonin receptor involved in the reproductive process of the Pacific abalone, Haliotis discus hannai.

abstract：:A method is described which demonstrates the posibility of visualizing protein-complexed DNA by using pronase for both deproteinization and spreading of DNA for electron microscopy. The results show that proteolytic digestion is complete even under conditions of short formaldehyde fixation and pronase is an excellent ...

journal_title：Molecular biology reports

authors： Tsaneva I,Tsanev R

更新日期：1979-08-31 00:00:00

abstract：UNLABELLED:Hepatocellular carcinoma (HCC) is a worldwide neoplasm for which early diagnosis is difficult and the prognosis is usually poor. Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. Although several COX-2 inhibitors have been used in hepatoma therapy, the ...

journal_title：Molecular biology reports

authors： Mohamed FZ,Hussein YM,El-Deen IM,Sabea MS

更新日期：2014-03-01 00:00:00

abstract：:Correct classification of genomic variants causing potentially aberrant splicing is of utmost importance for patient management, especially in clinically actionable genes such as BRCA1/2. In this article, we report molecular evaluation of the BRCA1 c.439T>C (rs794727800, p.Leu147=) variant based on RNA of a patient su...

journal_title：Molecular biology reports

authors： Minucci A,Mazzuccato G,D'Indinosante M,Di Nardo L,Concolino P,De Bonis M,Urbani A,Scambia G,Fagotti A,Capoluongo E

更新日期：2020-02-01 00:00:00

abstract：:Flavonoids are the main flavor components and functional ingredients in tea, and the shikimic acid pathway is considered as one of the most important pathways in flavonoid biosynthesis, but little was known about the function of regulatory genes in the metabolism phenolic compounds in tea plant (Camellia sinensis), es...

journal_title：Molecular biology reports

authors： Zhu XJ,Zhao Z,Xin HH,Wang ML,Wang WD,Chen X,Li XH

更新日期：2016-10-01 00:00:00

abstract：:CD40 signaling plays a critical role in the survival rate of gastric cancer patients. Tumour samples were collected from 73 patients with who were diagnosed as gastric cancer in general surgery department in the 1st affiliated hospital of Suzhou University between September 2002 and July 2003. All patients had not rec...

journal_title：Molecular biology reports

authors： Li R,Chen WC,Pang XQ,Tian WY,Wang WP,Zhang XG

更新日期：2012-09-01 00:00:00

abstract：:The oligochaete earthworm, Eudrilus eugeniae is capable of regenerating both anterior and posterior segments. The present study focuses on the transcriptome analysis of earthworm E. eugeniae to identify and functionally annotate the key genes supporting the anterior blastema formation and regulating the anterior regen...

journal_title：Molecular biology reports

authors： Paul S,Balakrishnan S,Arumugaperumal A,Lathakumari S,Syamala SS,Arumugaswami V,Sivasubramaniam S

更新日期：2020-12-11 00:00:00

abstract：:The small molecules already existing on the earth can be assembled to biological macromolecules in the presence of the suitable tool. A workman must sharpen his tools if he is to do his work well. The tool must be specific, delicate and automatic. Obviously, it is enzyme. Therefore, to explore the origin of life we mu...

journal_title：Molecular biology reports

authors： Yin X,Yuan Z

更新日期：2009-02-01 00:00:00

abstract：:The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice. The tumor xenograft models were established and randomly assigned to 4 groups: control group, Endostar group (1.5 mg/kg day, once daily for 3 weeks), chemotherap...

journal_title：Molecular biology reports

authors： Chang L,Guo F,Lv Y,Wang Y,Huo B,Wang L,Liu W

更新日期：2013-01-01 00:00:00

abstract：:Epidemiological studies found inconsistent results on the association of two variants on TGFBR1 (TGFBR1*6A and Int7G24A) with colorectal cancer (CRC) risk. The present study was aimed to evaluate the association of these two variants with CRC susceptibility via the meta-analysis methods. For variant TGFBR1*6A, nine re...

journal_title：Molecular biology reports

authors： Zhang X,Wu L,Sheng Y,Zhou W,Huang Z,Qu J,Gao G,Cai D,Zhang M

更新日期：2012-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a newly identified class of non-coding small RNAs of about 21-24 nucleotides. They play important roles in multiple biological processes by degrading targeted mRNAs or repressing mRNA translation. To date, a total of 2,043 plant miRNAs are present in the miRNA Registry database (miRBase Release ...

journal_title：Molecular biology reports

authors： Lang Q,Jin C,Lai L,Feng J,Chen S,Chen J

更新日期：2011-03-01 00:00:00

abstract：:Hypertension is a risk factor for the cardiovascular diseases. Although, several drugs are used to treat hypertension, the success of the antihypertensive therapy is limited. Resveratrol decreases blood pressure in animal models of hypertension. This study researched the mechanisms behind the effects of resveratrol on...

journal_title：Molecular biology reports

authors： Han S,Uludag MO,Usanmaz SE,Ayaloglu-Butun F,Akcali KC,Demirel-Yilmaz E

更新日期：2015-01-01 00:00:00

abstract：:In the Eastern province of Saudi Arabia, thalassemia is highly common. Data on the effect of alpha globin gene variation on the concentration of iron on transfusion dependent Saudis are scanty. A total of 166 transfusions dependent β-thalassemia were included in this study to understand association between the alpha g...

journal_title：Molecular biology reports

authors： AbdulAzeez S,Almandil NB,Naserullah ZA,Al-Jarrash S,Al-Suliman AM,ElFakharay HI,Borgio JF

更新日期：2020-01-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:Four housekeeping genes named Lbbeta-Actin1, Lbbeta-Actin2, Lbalpha-Tubulin, and LbGapdh were cloned from Liposcelis bostrychophila using the combined techniques of reverse transcriptase-PCR (RT-PCR) with rapid amplification of cDNA ends (RACE). The GenBank accession numbers were FJ196622, FJ447483, FJ595242, and FJ59...

journal_title：Molecular biology reports

authors： Jiang HB,Liu YH,Tang PA,Zhou AW,Wang JJ

更新日期：2010-02-01 00:00:00

abstract：:One of the most crucial steps for preventing viral pandemics is the early detection of the causative virus on site. Various molecular and immunological approaches have been developed for virus detection. In this study, we investigated the utility of the recently introduced convection polymerase chain reaction (cPCR) p...

journal_title：Molecular biology reports

authors： Lee MH,Song KY,Hwang HJ,Kim JH,Hwang I

更新日期：2019-10-01 00:00:00

abstract：:Birch (Betula platyphylla), an eminent tree species in Northeast and Inner Mongolia of China, has been widely used in architecture, furniture, and paper making in recent years. In order to retrieve genes involved in early development of B. platyphylla male inflorescence, RNA populations extracted from early and late d...

journal_title：Molecular biology reports

authors： Xing L,Liu XM

更新日期：2012-02-01 00:00:00

abstract：:As initial steps to define how the 26S proteasome degrades ubiquitinated proteins in plants, we have characterized many of the subunits that comprise the proteolytic complex from Arabidopsis thaliana. A set of 23 Arabidopsis genes encoding the full complement of core particle (CP) subunits and a collection encoding 12...

journal_title：Molecular biology reports

authors： Fu H,Girod PA,Doelling JH,van Nocker S,Hochstrasser M,Finley D,Vierstra RD

更新日期：1999-04-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:Accurate normalization of gene expression with qRT-PCR depends on the use of appropriate reference genes (RGs) for the species under a given set of experimental conditions. Multiple RGs for gene expression analysis of soybean exposed to heavy metal stress treatment have not been reported in the literature. In this stu...

journal_title：Molecular biology reports

authors： Wang Y,Yu K,Poysa V,Shi C,Zhou Y

更新日期：2012-02-01 00:00:00

abstract：:Membrane-bound Δ9 desaturase perform oxygenated desaturation reactions to insert the first double bonds within fatty acyl chains between C9 and C10 positions of most saturated substrates. Arthrospira platensis, a blue green microalga, is an important source of polyunsaturated fatty acids (PUFA) such as oleic, linoleic...

journal_title：Molecular biology reports

authors： Ben Amor F,Ben Hlima H,Abdelkafi S,Fendri I

更新日期：2018-12-01 00:00:00

abstract：:The beta class of the carbonic anhydrase (CA) enzyme family has been found in plants, yeast, bacteria and algae, but not in animals. Also, little is known concerning the CAs of C. elegans. Genes possibly encoding beta-CAs were revealed by in silico analysis of the C. elegans genome. Amino acid sequence and 3D structur...

journal_title：Molecular biology reports

authors： Fasseas MK,Tsikou D,Flemetakis E,Katinakis P

更新日期：2010-07-01 00:00:00

abstract：:MAPK cascade is an important intracellular signaling module and function as a convergent point for crosstalk during abiotic stress signaling. In this study SbMAPKK gene has been isolated from Salicornia brachiata, a highly salt tolerant plant growing in costal marshes of Gujarat, India. The SbMAPKK gene is 1,023 bp lo...

journal_title：Molecular biology reports

authors： Agarwal PK,Gupta K,Jha B

更新日期：2010-02-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the most common cancers, and rates of incidence and diagnosis of CRC have gradually increased. Carcinoembryonic antigen (CEA) is overexpressed in patients with CRC and is associated with cell adhesion, anoikis resistance, and promotion of metastasis to the liver. 5-Fluorouracil (5-FU)...

journal_title：Molecular biology reports

authors： Lee JH,Lee SW

更新日期：2019-08-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Start codon targeted (SCoT) polymorphic markers were used to assess genetic relationships among 64 grape varieties. Seventeen informative primers were selected from 36 SCoT primers based on their ability to produce clear and repeatable polymorphic and unambiguous bands among the varieties. A total of 131 bands were pr...

journal_title：Molecular biology reports

authors： Guo DL,Zhang JY,Liu CH

更新日期：2012-05-01 00:00:00

abstract：:Free cytoplasmic 40S mRNP particles from rat liver were treated with EDTA and separated into two populations of RNP particles with sedimentation maxima of 20S and 35S, respectively. A characteristic set of distinct scRNAs is found for 20S and 35S RNP particles. The sequences of two of the most abundant scRNAs from 20S...

journal_title：Molecular biology reports

authors： Villringer A,Kühn B,Schneider K,Andus T,Michels K,Northemann W,Krupp G,Walckhof B,Gross HJ,Klump H,Kroll A,Branlant C,Heinrich PC

更新日期：1983-05-01 00:00:00

abstract：:Molluscs are an extraordinarily diverse group of animals and to discriminate them based on one molecular marker/gene is very difficult because of the too fast or slow rate of nucleotide substitution. In the study, the tropomyosin cds (coding sequences) of 43 animal species were analyzed, the results of which suggested...

journal_title：Molecular biology reports

authors： Wang X,Li L,Xu F,Zhang G

更新日期：2011-10-01 00:00:00

abstract：:3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors has been shown to reduce the progression of renal disease independent of cholesterol-lowering effect, but the mechanism of potential protective effect remains unclear. Here, we investigate the effect of fluvastatin on activation of nuclear factor-κB ...

journal_title：Molecular biology reports

authors： Gao P,Wu X,Shui H,Jia R

更新日期：2012-04-01 00:00:00

abstract：:The purpose of our research is to elucidate whether oxLDL activates P2X7R in cultured human podocytes and if the activation of P2X7R leads to podocyte apoptosis. Additionally, we explore the underlying mechanism involved in podocyte apoptosis. Immortalized human podocytes were incubated with oxLDL (80 µg/ml), P2X7R an...

journal_title：Molecular biology reports

authors： Zhu Y,Li Q,Xun W,Chen Y,Zhang C,Sun S

更新日期：2019-08-01 00:00:00

abstract：:The treatment of anaplastic astrocytoma (AA) is controversial. New chemotherapeutic approaches are needed for AA treatment. Temozolomide (TMZ) is one of the chemotherapeutic drugs for the treatment of AA. The cytotoxic effects of TMZ can be removed by the MGMT (O(6)-methylguanine-DNA methyltransferase) enzyme. Then, c...

journal_title：Molecular biology reports

authors： Ugur HC,Taspinar M,Ilgaz S,Sert F,Canpinar H,Rey JA,Castresana JS,Sunguroglu A

更新日期：2014-02-01 00:00:00