Microarray analysis of high-glucose diet-induced changes in mRNA expression in jejunums of C57BL/6J mice reveals impairment in digestion, absorption.

abstract：:Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indic...

journal_title：Molecular biology reports

authors： Hayashida K,Kohno S

更新日期：2009-07-01 00:00:00

abstract：:ATP-binding cassette transporter A1 (ABCA1) modulates plasma levels of high density lipoprotein (HDL), a cardiovascular protecting factor. Tree shrew was considered to be an animal protected from atherosclerosis characterized by high proportion of HDL in plasma. The cDNA clones and expression of tree shrew ABCA1 was i...

journal_title：Molecular biology reports

authors： Zeng WW,Zhou B,Liu HR,Sun GT,Chen BS

更新日期：2009-03-01 00:00:00

abstract：:Long non-coding RNAs (LncRNAs) are non-coding RNAs. The potential roles of lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to assess the expression levels of LY86-AS1 and HCG27_201 in T2DM patients and a healthy control group. We obtained whole blood and serum samples from 100 T2DM...

journal_title：Molecular biology reports

authors： Saeidi L,Ghaedi H,Sadatamini M,Vahabpour R,Rahimipour A,Shanaki M,Mansoori Z,Kazerouni F

更新日期：2018-12-01 00:00:00

abstract：:The quantitative changes of double-stranded RNA components of nuclear ribonucleo-protein particles containing pre-mRNA was investigated in the course of incubation of particles at 37 degrees C. The incubation of purified nuclear particles revealed the fragmentation of long double-stranded RNA sequences into shorter st...

journal_title：Molecular biology reports

authors： Molnar J,Samarina OP

更新日期：1976-11-01 00:00:00

abstract：:Recent evidence supports a role of Toll-like receptor (TLR) signaling in the development of atherosclerotic lesions. It was confirmed that the presence of functional TLR4 promotes a proinflammatory phenotype and proliferation of vascular smooth muscle cells (VSMCs). Here we tested whether designed TLR4 small interferi...

journal_title：Molecular biology reports

authors： Li H,Xu H,Liu S

更新日期：2011-02-01 00:00:00

abstract：:Familial Mediterranean fever is an autosomal recessive disorder characterized by recurrent attacks of abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible for the disease. The objective of this study was to identify the frequency and distribution of 12 MEFV mutations in 153 Syrian patients and ...

journal_title：Molecular biology reports

authors： Jarjour RA

更新日期：2010-01-01 00:00:00

abstract：:Transcriptome from high throughput sequencing-by-synthesis is a good resource of molecular markers. In this study, we present utility of massively parallel sequencing by synthesis for profiling the transcriptome of red pepper (Capsicum annuum L. TF68) using 454 GS-FLX pyrosequencing. Through the generation of approxim...

journal_title：Molecular biology reports

authors： Lu FH,Cho MC,Park YJ

更新日期：2012-03-01 00:00:00

abstract：:Chrysanthemum indicum L. is a traditional oriental medicinal herb prepared as a tea from flowers that have been used in China and South Korea since ancient times. It has a long history in the treatment of hypertension, inflammation, and respiratory diseases. Among Chrysanthemum species, C. indicum has more active chem...

journal_title：Molecular biology reports

authors： Abid S,Kaliraj L,Arif MH,Hurh J,Ahn JC,Yang DC,Jung SK

更新日期：2020-10-01 00:00:00

abstract：:Adriamycin is one of the most effective and useful antineoplastic agents. Acute doxorubicin cardiotoxicity involved cardiomyocyte apoptosis. In this study, we investigated whether adriamycin induced myocardium apoptosis through activation of nuclear factor kappaB in rat. Forty male Wistar rats were randomly divided in...

journal_title：Molecular biology reports

authors： Li S,E M,Yu B

更新日期：2008-12-01 00:00:00

abstract：:Bud dormancy in perennial plants adapts to environmental and seasonal changes. Bud dormancy is of ecological interest because it affects forest population growth characteristics and is of economical interest because it impacts wood production levels. To understand Pinus sylvestris L. var. mongolica litv. bud-dormancy ...

journal_title：Molecular biology reports

authors： Bi YD,Wei ZG,Shen Z,Lu TC,Cheng YX,Wang BC,Yang CP

更新日期：2011-02-01 00:00:00

abstract：:Chemerin, as a new member of adipokines family, is highly expressed in adipose tissue in rodent and its expression increases with obesity. Moreover, chemerin has been reported to have significant relationship with metabolic syndrome and insulin sensitivity. Here, the gene encoding chemerin from Xiang pig was cloned. T...

journal_title：Molecular biology reports

authors： Yang H,Li F,Kong X,Yuan X,Lian G,Geng M,Li T,Yin J,Yin Y

更新日期：2012-02-01 00:00:00

abstract：:Seed weight and plant height are important agronomic traits and contribute to seed yield. The objective of this study was to identify QTLs underlying these traits using an intra-specific mapping population of chickpea. A F11 population of 177 recombinant inbred lines derived from a cross between SBD377 (100-seed weigh...

journal_title：Molecular biology reports

authors： Gupta S,Kumar T,Verma S,Bharadwaj C,Bhatia S

更新日期：2015-11-01 00:00:00

abstract：:Here, we document changes in cell motility and organization of the contractile apparatus of human umbilical cord Wharton's jelly mesenchymal stem cells (MSCWJ-1) in the process of replicative senescence. Colocalization dynamics of F-actin and actin-binding proteins (myosin-9, α-actinin-4, RhoA) were examined in the MS...

journal_title：Molecular biology reports

authors： Bobkov D,Polyanskaya A,Musorina A,Lomert E,Shabelnikov S,Poljanskaya G

更新日期：2020-05-01 00:00:00

abstract：:The aim of this study was to elucidate the effects of sex hormones on activity of the ABCG2 promoter in different cell lines. T47D cells and BeWo cells were used as models for ABCG2-expressing cell lines, and luciferase assays using ABCG2 promoter-luciferase constructs were performed. It was shown that progesterone in...

journal_title：Molecular biology reports

authors： Yasuda S,Kobayashi M,Itagaki S,Hirano T,Iseki K

更新日期：2009-09-01 00:00:00

abstract：:Osteocytic potentiality of human CD34+ stem cells explored in the present study by generating in vitro agarose gel 3D model to understand the bone ossification process. The G-CSF and IL-3 mobilized human CD34+ stem cells isolated apheretically from donor peripheral blood and purity of the cells was assessed by FACS an...

journal_title：Molecular biology reports

authors： Srikanth L,Sunitha MM,Kumar PS,Chandrasekhar C,Vengamma B,Sarma PV

更新日期：2016-11-01 00:00:00

abstract：:Protein phosphorylation is one of the most fundamental types of post-translational modifications and it plays a vital role in various cellular processes of eukaryotes. Among three types of phosphorylation i.e. serine, threonine and tyrosine phosphorylation, tyrosine phosphorylation is one of the most frequent and it i...

journal_title：Molecular biology reports

authors： Khan YD,Rasool N,Hussain W,Khan SA,Chou KC

更新日期：2018-12-01 00:00:00

abstract：:Ribosomes were isolated from baby hamster kidney fibroblasts, either 20 min or 2 days after labelling with radioactive amino acids, and their proteins subjected to two-dimensional polyacrylamide gel electrophoresis. No significant differences were observed between the amounts of radioactivity associated with the posit...

journal_title：Molecular biology reports

authors： Kennedy IM,Leader DP

更新日期：1980-12-31 00:00:00

abstract：:Syndecan-1 has been implicated in tumorigenesis and progression of various human malignancies. Recent studies have demonstrated that syndecan-1 may have a different function and biological activity depending on the specific tumor type. Therefore, the aim of this study was to investigate the clinical significance of sy...

journal_title：Molecular biology reports

authors： Xu Y,Yuan J,Zhang Z,Lin L,Xu S

更新日期：2012-09-01 00:00:00

abstract：:Protein phosphatases type 2C (PP2Cs) from group A, which includes the ABI1/HAB1 and PP2CA branches, are key negative regulators of ABA signaling. HAI-1 gene had been shown to affect both seed and vegetative responses to ABA, which is one of PP2Cs clade A in Arabidopsis thaliana. Transgenic plants containing pHAI-1::GU...

journal_title：Molecular biology reports

authors： Zhang J,Li X,He Z,Zhao X,Wang Q,Zhou B,Yu D,Huang X,Tang D,Guo X,Liu X

更新日期：2013-03-01 00:00:00

abstract：:Laparoscopic surgery techniques have been increasingly preferred to classic laparotomy by surgeons since 1987. However, this method may have some side effects on different intraabdominal organs including kidneys. The aim of this study is to evaluate the effects of different pressures of CO2 on p53 related apoptosis in...

journal_title：Molecular biology reports

authors： Tosun M,Yucel M,Kucuk A,Sezen S

更新日期：2014-10-01 00:00:00

abstract：:The objective of this study was to analyze possible associations between single nucleotide polymorphisms (SNPs) in the Myf5 gene with chicken growth and reproductive traits. SNPs in Myf5 of the Jinghai yellow chicken were detected by the polymerase chain reaction single-strand conformation polymorphism method and the ...

journal_title：Molecular biology reports

authors： Tang Y,Zhang T,Zhang G,Wang J,Fan Q,Chen X,Wei Y,Han K,Wang Y

更新日期：2014-10-01 00:00:00

abstract：:The q11.2 region on chromosome 22 contains numerous low-copy repeats that lead to deleted or duplicated regions in the chromosome, thereby resulting in different syndromes characterized by intellectual disabilities or congenital anomalies. The association between patient phenotypes and 22q11.2 copy number abnormalitie...

journal_title：Molecular biology reports

authors： Cai M,Lin N,Su L,Wu X,Xie X,Li Y,Lin Y,Huang H,Xu L

更新日期：2020-10-01 00:00:00

abstract：:Two new thermophilic type II restriction endonucleases, which we designated as Bsu2413I and Bfi2411I, have been isolated from gram-positive thermophilic bacteria Bacillus subtilis strain 2413 and Bacillus firmus strain 2411 respectively and partially purified. The restriction endonucleases were extracted from cell ext...

journal_title：Molecular biology reports

authors： Jutur PP,Hoti SL,Reddy AR

更新日期：2004-06-01 00:00:00

abstract：:Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study is...

journal_title：Molecular biology reports

authors： Shen W,Shi HM,Fan WH,Luo XP,Jin B,Li Y

更新日期：2011-08-01 00:00:00

abstract：:The widely studied candidate genes of the renin-angiotensin-aldosterone system, angiotensinogen (AGT), and angiotensin II receptor type 1 (AGTR1), are implicated in the development of diabetic nephropathy (DN). A number of studies have evaluated the association between the functional polymorphisms, AGT M235T and AGTR1...

journal_title：Molecular biology reports

authors： Ding W,Wang F,Fang Q,Zhang M,Chen J,Gu Y

更新日期：2012-02-01 00:00:00

abstract：:The studies conducted aimed at evaluating the genetic diversity within and between varieties of conservative flocks of geese, using the polymorphism of 14 microsatellite sequences. The experimental material included conservative flocks of geese the following indigenous breeds and varieties kept in Poland: Kielecka (Ki...

journal_title：Molecular biology reports

authors： Parada R,Książkiewicz J,Kawka M,Jaszczak K

更新日期：2012-05-01 00:00:00

abstract：:α-Synuclein is a presynaptic neuronal protein that is abundant in the human brain and is linked genetically and neuropathologically to Parkinson's disease (PD). The E46K mutation of the α-synuclein gene has been linked to autosomal dominant early-onset of PD. Crocin is a carotenoid chemical compound of saffron that ha...

journal_title：Molecular biology reports

authors： Ghasemi Tigan M,Ghahghaei A,Lagzian M

更新日期：2019-08-01 00:00:00

abstract：:Free cytoplasmic 40S mRNP particles from rat liver were treated with EDTA and separated into two populations of RNP particles with sedimentation maxima of 20S and 35S, respectively. A characteristic set of distinct scRNAs is found for 20S and 35S RNP particles. The sequences of two of the most abundant scRNAs from 20S...

journal_title：Molecular biology reports

authors： Villringer A,Kühn B,Schneider K,Andus T,Michels K,Northemann W,Krupp G,Walckhof B,Gross HJ,Klump H,Kroll A,Branlant C,Heinrich PC

更新日期：1983-05-01 00:00:00

abstract：:The Italian National Reference Center for Echinococcosis (CeNRE, Sassari, Italy) set up a diagnostic protocol of "one-step-PCR" useful for the detection of E. granulosus sensu stricto (E.g.s.s.) and the identification of its genotype (G1-G3). The purpose of this work was to perform the validation of the "PCR E.g.s.s."...

journal_title：Molecular biology reports

authors： Santucciu C,Masu G,Mura A,Peruzzu A,Piseddu T,Bonelli P,Masala G

更新日期：2019-04-01 00:00:00

abstract：:The recombinant catalytic subunit of human protein kinase CK2 bas been mutagenised at the C-terminal region in an attempt to induce this tail to fold. We suppose in fact that this unstructured C-terminus just might be responsible for the high degradability of the human enzyme. On the basis of theoretical calculations ...

journal_title：Molecular biology reports

authors： Grasselli E,Noviello G,Rando C,Nicolini C,Vergani L

更新日期：2003-06-01 00:00:00