Abstract:
:The objective of this study was to analyze possible associations between single nucleotide polymorphisms (SNPs) in the Myf5 gene with chicken growth and reproductive traits. SNPs in Myf5 of the Jinghai yellow chicken were detected by the polymerase chain reaction single-strand conformation polymorphism method and the haplotypes were analyzed. Eight SNPs were identified in the exons of Myf5. Nine haplotypes were established in a group of 379 Jinghai yellow chickens. In terms of growth traits, least square analysis showed that haplotype H1H5 had significant effects on weight at weeks 8 and 12 (P < 0.05). Haplotype H2H6 had significant effects on weight at weeks 12 and 14 (P < 0.05). For reproductive traits, H1H5 had higher body weight for the first egg than H1H4 and H2H4 (P < 0.05), and H1H3 (P < 0.01). H1H3 had a poor performance in average egg weight at 300 days. On the other hand, H1H3 had an advantage in egg number at 300 days. The results showed that SNPs of Myf5 have certain effects on growth and reproductive traits in Jinghai yellow chickens, which can be used in marker-assisted selection to accelerate chicken genetic progress.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Tang Y,Zhang T,Zhang G,Wang J,Fan Q,Chen X,Wei Y,Han K,Wang Ydoi
10.1007/s11033-014-3569-8subject
Has Abstractpub_date
2014-10-01 00:00:00pages
6837-44issue
10eissn
0301-4851issn
1573-4978journal_volume
41pub_type
杂志文章abstract::Mouse U26 has been defined as a 2-aminoadipic 6-semialdehyde dehydrogenase. It was speculated to be a PQQ-dependent AAS dehydrogenase due to the research of demonstrating PQQ as a new B vitamin. We isolated a novel human cDNA from the human fetal brain cDNA library we constructed. Its deduced protein was most related ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-003-2716-4
更新日期:2005-03-01 00:00:00
abstract::The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies ha...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-9955-y
更新日期:2011-06-01 00:00:00
abstract::Dipeptidyl peptidase III (DPP III) is an emerging biomarker of human cancers. Expression, specificity, and function of human DPP III (hDPP III) mRNA variant I (V-I), II (V-II), and III (V-III) are poorly understood. Here, we investigated expression of these variants in multiple human tumor derived cell lines. DNA sequ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-016-3996-9
更新日期:2016-06-01 00:00:00
abstract::Abnormally protein aggregation and deposition are key pathological features of ALS, which may related with dysfunctional cellular autophagy. In the current study, we found that, compared with wtSOD1 cells, serum starvation treatment resulted in significant higher percentage of apoptosis in mutSOD1 cells; Lithium treat...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05071-4
更新日期:2019-12-01 00:00:00
abstract::We report the characterization of VvIAA9, an auxin/indole-3-acetic acid (Aux/IAA) protein, in grapevine (Vitis vinifera L.). VvIAA9 was expressed abundantly in leaves and berries. VvIAA9 transcription was drastically upregulated from anthesis to onset of ripening (termed véraison), in which berry diameter rapidly incr...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1625-9
更新日期:2012-07-01 00:00:00
abstract::The novel dipstick DNA extraction method was tested for its reliability and usability for biological barcoding in comparison to a commercial kit and to a simplified isopropanol precipitation method using crayfish gill tissue. Following DNA extraction, the mitochondrial COI-gene was amplified in a PCR-reaction using a ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05083-0
更新日期:2019-12-01 00:00:00
abstract::Expression of recombinant proteins is a standard technique in molecular biology and a wide variety of prokaryotic as well as eukaryotic expression systems are currently in use. A limiting step is often the purification of the expressed recombinant protein, particularly if mammalian expression systems that yield low ex...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF01674434
更新日期:1993-10-01 00:00:00
abstract::The GRAS gene family is a family of transcription factors that regulates plant growth and development. Despite being well-studied in many plant species, little is known about this gene family in orchardgrass (Dactylis glomerata L.), one of the top four economically important perennial forage grasses cultivated worldwi...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05279-9
更新日期:2020-03-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic inflammatory disease in which numerous cells and mediators affect inflammatory conditions and disease severity. To compare the serum levels of adiponectin, vitamin D, copper, and zinc in patients with RA and to investigate the relationship between these parameters and RA severity...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-04682-1
更新日期:2019-04-01 00:00:00
abstract::MicroRNAs (miRNAs) are a newly identified class of non-coding small RNAs of about 21-24 nucleotides. They play important roles in multiple biological processes by degrading targeted mRNAs or repressing mRNA translation. To date, a total of 2,043 plant miRNAs are present in the miRNA Registry database (miRBase Release ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0260-6
更新日期:2011-03-01 00:00:00
abstract::The aim of this study was to identify molecular markers to be applied to marker-assisted selection. Three SNPs of the FASN gene were studied. PCR-RFLP was used for genotyping. The SNPs g.17924A>G, g.17860C>T and g.15603A>G all in the FASN gene were genotyped using the enzymes MscI, DdeI and Hae III, respectively. The ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1883-6
更新日期:2012-12-01 00:00:00
abstract::A chromosomal fragment containing purA, the nearest marker from the replication origin of the Bacillus subtilis chromosome, was highly purified as a complex containing at least proteins and being solubilized easily during cell lysis. The complex had a markedly higher sedimentation rate (70-120S) than the bulk of the s...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00356932
更新日期:1976-07-01 00:00:00
abstract::The lily-of-the-valley Convallaria (Asparagaceae) consists of three herbaceous perennial species. The plants are commonly found in northern hemisphere, and are best-known for their ornamental and pharmaceutical value. In order to assess the genetic structure, diversity and demographic history of Convallaria species, 1...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05376-9
更新日期:2020-04-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality, influenced by both environmental factor and genetic factor. ADAM33 gene was found to be associated with asthma, declined lung function and COPD. The purpose of the study was to test whether S...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0637-6
更新日期:2011-11-01 00:00:00
abstract::Mouse DNA and chromatin were melted on hydroxyapatite and the denaturation profiles of ribosomal and satellite DNAs were followed by hybridization with their complementary RNAs. Neither ribosomal nor bulk DNA had significantly different melting profiles in chromatin as compared to DNA. However, most of satellite DNA e...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00368300
更新日期:1977-06-01 00:00:00
abstract::The phosphoenolpyruvate (PEP) carboxylase is regulated at the levels of transcription and post-translation in C4 plants in light and abundantly accumulates in leaf mesophyll cells. We report here developmental and photosynthetic regulation of stably accumulated Bacillus thuringiensis δ-endotoxin under the control of P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0369-7
更新日期:2011-04-01 00:00:00
abstract::The complement factor H (CFH) Y402H (T1277C) gene polymorphism has been reported to be associated with coronary heart disease (CHD), but results were conflicting. To evaluate the role of the variant in CHD, we performed meta-analyses of all available data. Both electronic and manual searches were performed, all releva...
journal_title:Molecular biology reports
pub_type: 杂志文章,meta分析
doi:10.1007/s11033-010-9956-x
更新日期:2011-06-01 00:00:00
abstract::The melanocortin-4 receptor (MC4R) plays an important role in weight and energy homeostasis and it is associated with lower risk to develop obesity and lower body mass index. The contribution of MC4R mutation to obesity in Vojvodina (Northern Province of Serbia), known as a region with the largest number of overweight...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-009-9500-z
更新日期:2010-01-01 00:00:00
abstract::Fusarium head blight (FHB), predominantly caused by Fusarium graminearum, is a destructive disease that poses a serious threat to wheat (Triticum aestivum L.) production around the world. A suppression subtractive hybridization (SSH) cDNA library was constructed from F. graminearum infected spikes of a resistant Belgi...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1823-5
更新日期:2012-10-01 00:00:00
abstract::The full-length MECPS cDNA sequence (designated as Chmecps, GenBank Accession No.: DQ415658) was isolated by rapid amplification of cDNA ends (RACE) for the first time from Cephalotaxus harringtonia. The full-length cDNA of Chmecps was 1,146 bp containing a 753 bp open reading frame (ORF) encoding a polypeptide of 250...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-008-9377-2
更新日期:2009-09-01 00:00:00
abstract::The aim of this study was to determine whether the Glutathione S-transferase M1 (GSTM1) and P1 (GSTP1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). Meta-analysis was performed on the associations between the GSTM1 and GSTP1 null genotypes and RA, and on the association between smoking or seroposit...
journal_title:Molecular biology reports
pub_type: 杂志文章,meta分析
doi:10.1007/s11033-012-1965-5
更新日期:2012-12-01 00:00:00
abstract::Recent studies suggest that the common variant in the GSTM1 and GSTT1 genes modifies the risk of coronary artery disease (CAD), however, it is unclear whether the risk of CAD modulated by variants in the GSTM1 and GSTT1 genes was associated with alterations of indices of oxidative stress and inflammation. Our study is...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-009-9877-8
更新日期:2010-01-01 00:00:00
abstract::The glutathione S-transferase (GST) family of enzymes is known to play a pivotal role in phase II of biotransformation of xenobiotics, environmental carcinogens and pharmacological drugs. The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstru...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-0287-8
更新日期:2011-03-01 00:00:00
abstract::Stomatal closure is a common adaptation response of plants to the onset of drought condition and its regulation is controlled by transcription factors. MYB60, a transcription factor involved in the regulation of light-induced stomatal opening, has been characterized in arabidopsis and grapevine. In this work, we studi...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-021-06168-5
更新日期:2021-01-27 00:00:00
abstract::Tumor necrosis factor-alpha (TNF-α) and interleukin 1 beta (IL-1β) genetic variants which resulting in TNF-α and IL-1 overproduction may increase susceptibility to autoimmune diseases such as atherosclerosis. We have studied the association of TNF-α G308A and IL-1β (+3953) C/T polymorphism with myocardial infarction i...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-0701-x
更新日期:2011-11-01 00:00:00
abstract::Combined treatment with niacin and chromium has been found to have a protective effect against oxidative damage to different tissues of hyperlipidemic rats. But its effects on vascular endothelial dysfunction are less clear. This study was performed to investigate the effect of combined treatment with niacin and chrom...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-008-9309-1
更新日期:2009-07-01 00:00:00
abstract::The Editor-in-Chief has decided to retract this article [1]. The article shows significant overlap with two prior publications by the same authors [2, 3], without providing the due citation and attribution. ...
journal_title:Molecular biology reports
pub_type: 已发布勘误,撤回出版物
doi:10.1007/s11033-019-04760-4
更新日期:2019-10-01 00:00:00
abstract::Drought is one of the major abiotic stresses that affect productivity in soybean (Glycine max L.) Several genes induced by drought stress include functional genes and regulatory transcription factors. The Arabidopsis thaliana DREB1D transcription factor driven by the constitutive and ABA-inducible promoters was introd...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3695-3
更新日期:2014-12-01 00:00:00
abstract::In the published original version, the complete list of authors was omitted. The complete list of contributing authors is updated with this Correction. ...
journal_title:Molecular biology reports
pub_type: 已发布勘误
doi:10.1007/s11033-018-4454-7
更新日期:2018-12-01 00:00:00
abstract::We have previously shown that angiotensin-converting enzyme (ACE) gene D allele is an independent risk factor for early onset coronary artery disease (CAD). Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. Regarding the high...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1027-4
更新日期:2012-03-01 00:00:00