Complement factor H Y402H gene polymorphism and coronary heart disease susceptibility: a meta-analysis.

abstract：:The goal of this study was to determine whether ultrasound (US) exposure combined with microbubble destruction could be used to enhance non-viral gene delivery in rat C6 glioma cells. Microbubbles were prepared and gently mixed with plasmid DNA. The mixture of the DNA and microbubbles was administered to cultured C6 c...

journal_title：Molecular biology reports

authors： Wang JF,Wu CJ,Zhang CM,Qiu QY,Zheng M

更新日期：2009-07-01 00:00:00

abstract：:ColE1 DNA replication is initiated by RNA II and inhibited by RNA I. Control of the replication occurs through the interaction between RNA I and RNA II. Therefore, RNases involved in the metabolism of RNA I and RNA II are expected to play a key role in the control of the ColE1 plasmid replication. RNase H, RNase E, RN...

journal_title：Molecular biology reports

authors： Jung YH,Lee Y

更新日期：1995-01-01 00:00:00

abstract：:Long term intake of high-glucose diet (HGD) may induce many diseases such as dyslipidemia, fatty liver and diabetes disease. Most of the research for molecular mechanisms of the association between HGD and the above diseases focus on the metabolism of glucose and lipid. However, there are few studies on molecular mech...

journal_title：Molecular biology reports

authors： Du D,Shi YH,Le GW

更新日期：2010-04-01 00:00:00

abstract：:β-Catenin plays a crucial role in embryonic development and responds to the activation of several signal transduction pathways. In this paper, in order to understand the functions of β-catenin gene in early embryonic development of Artemia sinica, the complete cDNA sequence was cloned for the first time using RACE tec...

journal_title：Molecular biology reports

authors： Li X,Hou L,Ma J,Liu Y,Zheng L,Zou X

更新日期：2012-01-01 00:00:00

abstract：:Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple neoplasms. The main purpose of this study was to investigate the expression of these miRNAs in bladder cancer (BCa) and to analyze the association between their expression profiles and clinical and epidemiological parameters. Ninety BCa specim...

journal_title：Molecular biology reports

authors： Boubaker NS,Spagnuolo M,Trabelsi N,Said R,Gurtner A,Regazzo G,Ayed H,Blel A,Karray O,Saadi A,Rammeh S,Chebil M,Rizzo MG,Piaggio G,Ouerhani S

更新日期：2020-02-01 00:00:00

abstract：:3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors has been shown to reduce the progression of renal disease independent of cholesterol-lowering effect, but the mechanism of potential protective effect remains unclear. Here, we investigate the effect of fluvastatin on activation of nuclear factor-κB ...

journal_title：Molecular biology reports

authors： Gao P,Wu X,Shui H,Jia R

更新日期：2012-04-01 00:00:00

abstract：:Oryza rufipogon L. (O. rufipogon) or a common wild rice, showed considerable aluminum (Al) tolerance. In this study, we examined the physiologic and genetic response of wild rice short term and long term to Al toxicity, respectively. In the short term study, morin staining, DAPI staining and aniline blue staining were...

journal_title：Molecular biology reports

authors： Cao Y,Lou Y,Han Y,Shi J,Wang Y,Wang W,Ming F

更新日期：2011-11-01 00:00:00

abstract：:The purpose of our research is to elucidate whether oxLDL activates P2X7R in cultured human podocytes and if the activation of P2X7R leads to podocyte apoptosis. Additionally, we explore the underlying mechanism involved in podocyte apoptosis. Immortalized human podocytes were incubated with oxLDL (80 µg/ml), P2X7R an...

journal_title：Molecular biology reports

authors： Zhu Y,Li Q,Xun W,Chen Y,Zhang C,Sun S

更新日期：2019-08-01 00:00:00

abstract：:Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study is...

journal_title：Molecular biology reports

authors： Shen W,Shi HM,Fan WH,Luo XP,Jin B,Li Y

更新日期：2011-08-01 00:00:00

abstract：:Our previous study revealed that CRB3 protein expression was reduced in clear cell renal cell carcinoma (ccRCC) and was associated with TNM stage, pathological grade, and poor prognosis of ccRCC. This study aimed to investigate if DNA methylation of CRB3 decreases its expression, subsequently leading to the progressio...

journal_title：Molecular biology reports

authors： Li P,Liu J,Li J,Liu P

更新日期：2019-08-01 00:00:00

abstract：:Safe harbor loci allow predicable integration of a transgene into the genome without perturbing endogenous gene activity and for decades have been exploited in the mouse to investigate gene function, generate humanised models and create tissue specific reporter and Cre recombinase expressing lines. Herein, we show tha...

journal_title：Molecular biology reports

authors： Browning J,Rooney M,Hams E,Takahashi S,Mizuno S,Sugiyama F,Fallon PG,Kelly VP

更新日期：2020-02-01 00:00:00

abstract：:The fat mass and obesity associated gene (FTO) has been widely reported to be associated with fat mass or fat deposition in different species. In the present study, we cloned both promoter and coding regions of the gene in pigs with over 5 Kb of sequence for the former region and 1,596 bp for the latter region. Compar...

journal_title：Molecular biology reports

authors： Huang J,Yang Y,Liu G,Zhang J,Dong X,Bai Y,Fang M

更新日期：2011-04-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:Maize (Zea mays L.) is an important model plant with an important role in agriculture and national economies all over the world. The optimum growth temperature of maize is between 25 and 28 °C. At temperatures below 12 °C, maize is vulnerable to damage by chilling stress. MYB transcription factors play important roles...

journal_title：Molecular biology reports

authors： Li M,Lin L,Zhang Y,Sui N

更新日期：2019-08-01 00:00:00

abstract：:Quinone oxidoreductases (NAD(P)H): quinone oxidoreductase 1 (NQO1) and NRH: quinone oxidoreductase 2 (NQO2) are an antioxidant enzyme, important in the detoxification of environmental carcinogens. Methylene-tetra-hydrofolate reductase (MTHFR), plays a role in folate metabolism and may have oncogenic role through disru...

journal_title：Molecular biology reports

authors： Mandal RK,Nissar K,Mittal RD

更新日期：2012-12-01 00:00:00

abstract：:Bud dormancy in perennial plants adapts to environmental and seasonal changes. Bud dormancy is of ecological interest because it affects forest population growth characteristics and is of economical interest because it impacts wood production levels. To understand Pinus sylvestris L. var. mongolica litv. bud-dormancy ...

journal_title：Molecular biology reports

authors： Bi YD,Wei ZG,Shen Z,Lu TC,Cheng YX,Wang BC,Yang CP

更新日期：2011-02-01 00:00:00

abstract：:Overexpression of domains of a human protein using recombinant DNA technology has been challenging because individual domains intend to accumulate as non-soluble aggregate when expressed separately. Studies on identifying right sequences for a domain to be able to fold independently may help understand the folding pat...

journal_title：Molecular biology reports

authors： Tiwary M,Agarwal N,Dinda A,Yadav SC

更新日期：2016-05-01 00:00:00

abstract：:Recombinant plasmids carrying a highly curved DNA structure are sometimes unstable in Escherichia coli. In order to know the underlying mechanism, several plasmids carrying one or two highly bent DNA segment(s) from the human adenovirus type 2 (Ad2) enhancer and/or origin region of phage lambda replication were system...

journal_title：Molecular biology reports

authors： Ohyama T,Miyano M,Sakuma S

更新日期：1999-12-01 00:00:00

abstract：:The purpose of this study is to investigate the effect of H2O2 on the aging of melanogenesis in human melanocytes. The staining of SA-β-galactosidase, an aging marker, was remarkably increased in the cells aged with H2O2 at 62.5 µM or more compared with young cells. The intracellular H2O2 level and melanin synthesis w...

journal_title：Molecular biology reports

authors： Ko H,Kim MM

更新日期：2019-04-01 00:00:00

abstract：:An RNA polymerase III transcript, 7SK nuclear RNA, was found to bear sequence homology to the B2 class of highly repeated elements in the mouse genome. Northern blot hybridizations between the small RNAs and two B2 clones showed that only one of them (p49C8) hybridized to 7SK RNA. Both clones, however, hybridized to 4...

journal_title：Molecular biology reports

authors： Gallant J,Lovely J,Krause M

更新日期：1987-01-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is an aggressive BC subtype characterized by HER2 overexpression/amplification. Genomic alterations of HER2 and others have been reported to be associated with, HER2 overexpression and prediction of trastuzumab-response. Here, we aimed at ide...

journal_title：Molecular biology reports

authors： Singla H,Kaur RP,Shafi G,Vashistha R,Banipal RPS,Kumar V,Munshi A

更新日期：2019-02-01 00:00:00

abstract：:Zbtb7a is a transcription factor whose dysfunction is correlated to the development of several types of cancer, including hepatocellular carcinoma (HCC). It generally acts as a repressor of transcription downregulating the expression of several target genes including oncosuppressors ARF and Rb. In this study, Zbtb7a w...

journal_title：Molecular biology reports

authors： Di Palo A,Siniscalchi C,Mosca N,Russo A,Potenza N

更新日期：2020-06-01 00:00:00

abstract：:Glioma is the most aggressive primary brain tumor. We have previously provided evidence that IFITM3 promoted glioma cells migration. However, the mechanism of how IFITM3 regulates glioma cells invasion and whether IFITM3 participates in TGF-β-mediated glioma invasion are still unknown. In this paper, we proved that IF...

journal_title：Molecular biology reports

authors： Wang H,Tang F,Bian E,Zhang Y,Ji X,Yang Z,Zhao B

更新日期：2020-01-01 00:00:00

abstract：:The complete mitochondrial genome of Pseudochauhanea macrorchis was determined and compared with other monogenean mitochondrial genomes from GenBank. The circular genome was 15,031 bp in length and encoded 36 genes (12 protein-coding genes, two ribosomal RNAs, and 22 transfer RNAs) typically found in flatworms. Struct...

journal_title：Molecular biology reports

authors： Zhang J,Wu X,Xie M,Li A

更新日期：2012-08-01 00:00:00

abstract：:The present study brings out the preventive role of (-)-epigallocatechin-gallate (EGCG) on cardiac mitochondrial metabolism and apoptosis in cigarette smoke (CS)-exposed rats. The CS-exposed rats showed significantly decreased activities of TCA cycle enzymes and mitochondrial enzymatic antioxidants, on the other hand,...

journal_title：Molecular biology reports

authors： Adikesavan G,Vinayagam MM,Abdulrahman LA,Chinnasamy T

更新日期：2013-12-01 00:00:00

abstract：:Various efforts made to stop the deadly epidemic of HIV since its discovery in 1983 remain unsuccessful and this virus still continues to claim the lives of millions of individuals every year. The viral effect in the cell is complicated and the overall disease outcome is the result of interaction between a few viral p...

journal_title：Molecular biology reports

authors： Sobti RC,Berhane N,Mehedi SA,Kler R,Hosseini SA,Kuttiat V,Wanchu A

更新日期：2010-01-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a world-wide health problem and its incidence accounts for 1.9-3.5% of all malignant tumors. Transforming growth factor beta/Smads (TGF-beta/Smads) signaling pathway plays an important role in oncogenesis, but its function and molecular mechanisms in OSCC remain unclear. Expressi...

journal_title：Molecular biology reports

authors： Wang X,Sun W,Bai J,Ma L,Yu Y,Geng J,Qi J,Shi Z,Fu S

更新日期：2009-05-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Increases of oxidatively modified protein in the cell have been associated with the aging process. Such an accumulation of damaged protein may be the result of increase in the rate of protein oxidation and/or decrease in the rate of degradation of oxidized protein. The multicatalytic proteinase or proteasome is known ...

journal_title：Molecular biology reports

authors： Conconi M,Friguet B

更新日期：1997-03-01 00:00:00

abstract：:Many environmental and genetic factors have been contributed to the development of systemic sclerosis (SSc). To determine whether IL-10 gene polymorphisms are associated with SSc, we conducted a meta-analysis approach. A total of eight studies involving 1,034 SSc cases and 1,815 controls were obtained by electronic da...

journal_title：Molecular biology reports

authors： Peng WJ,Wang BX,Pan HF,Tao JH,Zhang JQ,He Q,Xiao CC,Wang J

更新日期：2012-06-01 00:00:00