Proto-oncogene Zbtb7a represses miR-125a-5p transcription in hepatocellular carcinoma cells.

abstract：:Fusarium head blight (FHB), predominantly caused by Fusarium graminearum, is a destructive disease that poses a serious threat to wheat (Triticum aestivum L.) production around the world. A suppression subtractive hybridization (SSH) cDNA library was constructed from F. graminearum infected spikes of a resistant Belgi...

journal_title：Molecular biology reports

authors： Muhovski Y,Batoko H,Jacquemin JM

更新日期：2012-10-01 00:00:00

abstract：:Circular RNA (circRNA), a novel type of non-coding RNA that consists of a circular loop, has been demonstrated to act as a "sponge" for microRNAs (miRNAs). However, the role of circRNAs in keloid remains unknown. In this study, we investigated circRNA expression profiles in keloid to identify potential diagnostic and ...

journal_title：Molecular biology reports

authors： Shi J,Yao S,Chen P,Yang Y,Qian M,Han Y,Wang N,Zhao Y,He Y,Lyu L,Lu D

更新日期：2020-01-01 00:00:00

abstract：:The present meta-analysis of relevant case-control studies was conducted to investigate the possible relationships between genetic variations in the killer cell immunoglobulin-like receptor (KIR) gene clusters of the human KIR gene family and susceptibility to ankylosing spondylitis (AS). The following electronic data...

journal_title：Molecular biology reports

authors： Zuo HN,Wang ZL,Cui DR,Xin DJ

更新日期：2014-08-01 00:00:00

abstract：:To gain genetic insights into the protein-rich microalga, the transcriptome of Arthrospira platensis was sequenced using Illumina technology and de novo assembly was carried out. A total of 6023 transcripts were present in the transcriptome among which 4616 transcripts were annotated with specific functions. Gene onto...

journal_title：Molecular biology reports

authors： Kumaresan V,Sannasimuthu A,Arasu MV,Al-Dhabi NA,Arockiaraj J

更新日期：2018-10-01 00:00:00

abstract：:Study of retina specific genes would offer insights into retinal diseases and treatment. Based on the information from the gene expression profiles of mouse retinas, we here identified a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) as one of the highly expressed proteins in retina. Sequence analysis ...

journal_title：Molecular biology reports

authors： Qi S,Wang Y,Zhou M,Ge Y,Yan Y,Wang J,Zhang SS,Zhang S

更新日期：2011-06-01 00:00:00

abstract：:The full length cDNA sequence of the Tpt1/TCTP (Tumor protein, Translationally-controlled1) gene was identified from Common Carp (Cyprinus carpio, Cyprinidae), and was designated as CcTpt1 gene. The CDS is 510 bp and encodes a 170-amino acid peptide with a typical Tpt1 signature 2 domain, and is a typical Tpt1 protein...

journal_title：Molecular biology reports

authors： Jiang L,Wang Y,Cheng A,Zhang B,Ma L,Liu Y,Sun X

更新日期：2013-10-13 00:00:00

abstract：:In spite of much awareness, diabetes mellitus continues to remain one of major reasons for mortality and morbidity rate all over the globe. Free radicals cause oxidative stress which is responsible for causing diabetes. The recent advancements in elucidation of ARE/keap1/Nrf2 pathway can help in better understanding o...

journal_title：Molecular biology reports

authors： Behl T,Kaur I,Sehgal A,Sharma E,Kumar A,Grover M,Bungau S

更新日期：2021-01-03 00:00:00

abstract：:Seed development is a complex process controlled by temporal and spatial expression of many transcription factors (TF) inside the developing seed. In the present study, transcript profiles of all the 30 members of rice DofTFs from flowering to seed development stages were analyzed. It was found that 16 Dof genes besid...

journal_title：Molecular biology reports

authors： Gaur VS,Singh US,Kumar A

更新日期：2011-04-01 00:00:00

abstract：:Common bacterial blight (CBB), incited by Xanthomonas axonopodis pv. phaseoli (Xap), is a serious seed-borne disease of common bean (Phaseolus vulgaris L.) in both temperate and tropical production zones. The line HR45 is highly resistant to Xap infection on leaves and pods in both field and greenhouse. To understand ...

journal_title：Molecular biology reports

authors： Shi C,Chaudhary S,Yu K,Park SJ,Navabi A,McClean PE

更新日期：2011-01-01 00:00:00

abstract：:Sensitivity to phenylthiocarbamide (PTC) has a bimodal distribution pattern and the genotype of the TAS2R38 gene, which is composed of combinations of three coding single nucleotide polymorphisms (SNPs), p.A49P (c.145G>C), p.V262A (c.785T>C) and p.I296 V (c.886A>G), determines the ability or inability to taste PTC. In...

journal_title：Molecular biology reports

authors： Sagong B,Bae JW,Rhyu MR,Kim UK,Ye MK

更新日期：2014-03-01 00:00:00

abstract：:The transforming growth factor-β (TGF-β) signaling pathway is conserved across animals, and knowledge of its roles during the molt cycle in crustaceans is presently very limited. This study investigates the roles of the TGF-β receptor in molting-related muscle growth in Eriocheir sinensis. Using the RT-PCR and RACE te...

journal_title：Molecular biology reports

authors： Tian Z,Peng H,Deng W,Jiao C

更新日期：2020-01-01 00:00:00

abstract：:Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) plays a pivotal role in regulating T cell activation, which is believably critical for the outcome of hepatitis B virus (HBV) infection. The expression and function of CTLA-4 may be affected by gene polymorphisms. This study investigated the influence of CTLA-4 poly...

journal_title：Molecular biology reports

authors： Duan S,Zhang G,Han Q,Li Z,Liu Z,Chen J,Lv Y,Li N,Wang Y,Li M,Lou S,Yang M,Zhu Q,Xing F

更新日期：2011-11-01 00:00:00

abstract：:Various investigations have been so far performed for extraction of genomic DNA from plant tissues, in which the extracted intact DNA can be exploited for a diverse range of biological studies. Extraction of high quality DNA from leathery plant tissues (e.g., coniferous organs) appears to be a critical stage. Moreover...

journal_title：Molecular biology reports

authors： Barzegari A,Vahed SZ,Atashpaz S,Khani S,Omidi Y

更新日期：2010-02-01 00:00:00

abstract：:Approximately 90% of patients with advanced breast cancer develop bone metastases; an event that results in severe decrease of quality of life and a drastic deterioration in prognosis. Therefore, to increase the survival of breast cancer patients, the development of new therapeutic strategies to impair metastatic proc...

journal_title：Molecular biology reports

authors： Vashum Y,Premsingh R,Kottaiswamy A,Soma M,Padmanaban A,Kalaiselvan P,Samuel S

更新日期：2020-12-08 00:00:00

abstract：:The circular dichroism spectra of poly(dG). poly(dC) have been studied as a function of pH in 0.15 M NaCl solution. Acid titration to pH 2.5 showed two transitions, one around pH 5, the second below pH 3. These transitions are disproportionation reactions and are not due to the dissociation of the complexes. Alkaline ...

journal_title：Molecular biology reports

authors： Thiele D,Sarocchi MT,Guschlbauer W,Marck C

更新日期：1973-10-01 00:00:00

abstract：:The aim of this study was to describe the microbial communities in the distal gut of wild wolves (Canis lupus). Fecal samples were collected from three healthy unrelated adult wolves captured at the nearby of Dalai Lake Nature Reserve in Inner Mongolia of China. The diversity of fecal bacteria was investigated by cons...

journal_title：Molecular biology reports

authors： Zhang H,Chen L

更新日期：2010-12-01 00:00:00

abstract：:One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which encodes the major t...

journal_title：Molecular biology reports

authors： Seven M,Batar B,Unal S,Yesil G,Yuksel A,Guven M

更新日期：2014-01-01 00:00:00

abstract：:Eukaryotic initiation factors are found in the post-ribosomal subunits. We have analyzed the factor activities from the supernatant by means of zonal centrifugation followed by Sepharose-heparin affinity chromatography. They exist both as free factors, sedimenting in a broad range from 4 to 7S, and complexed with othe...

journal_title：Molecular biology reports

authors： Amesz H,Haubrich T,Voorma HO

更新日期：1979-05-31 00:00:00

abstract：:The myocyte enhancer factor 2C (MEF2C) is a member of the MEF2 family of transcription factors, involved in skeletal muscle development. In this study we report the cDNA sequence and isolate the 5' upstream region of the mef2c gene from porcine genomic DNA using PCR-based GenomeWalker. The open reading frame of porcin...

journal_title：Molecular biology reports

authors： Liu M,Xu DQ,Peng J,Zheng R,Li F,Jiang SW

更新日期：2011-10-01 00:00:00

abstract：:Body measurement and meat quality traits which play important roles in the assessment of productivity and economy in cattle were influenced by genes and environmental factors. Latest studies showed that LYR motif containing 1 (LYRM1) may be involved in influencing fatness deposition in animals. The objective of this s...

journal_title：Molecular biology reports

authors： Li Y,Gao J,Yang N,Fu C,Cheng G,Wang H,Zan L

更新日期：2013-02-01 00:00:00

abstract：:We performed PCR of many DNA fragments of 6-32 nucleotides in length. Some of the fragments expanded into kilobase lengths even in the absence of the complementary strand. The dramatic expansion was observed for (CA)8, (TG)8, (CA)4, (CA)6, (CA)12, (TG)4, (TG)6, (TG)12, (TC)10, (GA)10 and other single strands. Similar ...

journal_title：Molecular biology reports

authors： Reichová N,Kypr J

更新日期：2003-09-01 00:00:00

abstract：:We have chosen to test the safety of human intracerebroventricular (ICV) brain injections of autologous non-genetically-modified adipose-derived stromal vascular fraction (ADSVF). In this IRB-approved trial, 24 patients received ICV ADSVF via an implanted reservoir between 5/22/14 and 5/22/17. Seven others were inject...

journal_title：Molecular biology reports

authors： Duma C,Kopyov O,Kopyov A,Berman M,Lander E,Elam M,Arata M,Weiland D,Cannell R,Caraway C,Berman S,Scord K,Stemler L,Chung K,Khoudari S,McRory R,Duma C,Farmer S,Bravo A,Yassa C,Sanathara A,Singh E,Rapaport B

更新日期：2019-10-01 00:00:00

abstract：:Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. Direct exposure of human hepatoma cell line SMMC-7221 to hydrogen peroxide (H2O2) can induce apoptosis characterized by morphological evidence and fragmentation of DNA assayed by terminal deoxynucleotidyl transferase ...

journal_title：Molecular biology reports

authors： Huang C,Li J,Zheng R,Cui K

更新日期：2000-03-01 00:00:00

abstract：:The cell cycle is a complex and strictly controlled process, consisting of different phases. Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the dereg...

journal_title：Molecular biology reports

authors： Caglar HO,Biray Avci C

更新日期：2020-04-01 00:00:00

abstract：:Molecular detection of Giardia duodenalis by polymerase chain reaction (PCR) is difficult in faecal samples due to inhibitors that contaminate DNA preparations, or due to low cyst concentrations. In order to eliminate inhibitors, improve cyst recovery and molecular detection of G. duodenalis, different types of water,...

journal_title：Molecular biology reports

authors： Bezagio RC,Colli CM,Romera LIL,de Almeida CR,Ferreira ÉC,Mattia S,Gomes ML

更新日期：2020-02-01 00:00:00

abstract：:Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. The aim of this study was to quantify the expression of angiogenic (VEGF, HIF-1α, Angiopiotein-2) and anti-angiogenic (endostatin, angiostatin and Thrombospondin-1) factors and to discern their cl...

journal_title：Molecular biology reports

authors： Sharma BK,Srinivasan R,Kapil S,Singla B,Chawla YK,Chakraborti A,Saini N,Duseja A,Das A,Kalra N,Dhiman RK

更新日期：2013-10-01 00:00:00

abstract：:Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...

journal_title：Molecular biology reports

authors： Mancilla IA,Coatti GC,Biazi BI,Zanetti TA,Baranoski A,Marques LA,Corveloni AC,Lepri SR,Mantovani MS

更新日期：2019-12-01 00:00:00

abstract：:Methicillin resistant Staphylococcus aureus (MRSA) is one of the challenging bacterial pathogen due to its acquired resistance to the β lactam antibiotics. The Sortase A is an enzyme of Gram-positive bacteria including S. aureus to anchor surface proteins to the cell wall. Sortase A is well studied enzyme and consider...

journal_title：Molecular biology reports

authors： Uddin R,Saeed K

更新日期：2014-08-01 00:00:00

abstract：:Eukaryotic 20S proteasomes are complex oligomeric proteins. The maturation process of the 14 different alpha- and beta-subunits has to occur in a highly coordinate manner. In addition beta-subunits are synthesized as proproteins and correct processing has to be guaranteed during complex maturation. The structure forma...

journal_title：Molecular biology reports

authors： Schmidt M,Schmidtke G,Kloetzel PM

更新日期：1997-03-01 00:00:00

abstract：:Polyomavirus JC (JCPyV) is a ubiquitous human neurotropic virus that can cause progressive multifocal leukoencephalopathy (PML), sometimes as a consequence of drug treatment for disabling diseases, including Multiple Sclerosis. JCPyV expresses microRNAs (miRNAs), and in particular miR-J1-5p, but at now we have limited...

journal_title：Molecular biology reports

authors： Agostini S,Mancuso R,Costa AS,Guerini FR,Clerici M

更新日期：2020-11-01 00:00:00