Abstract:
:The plasticity of the central nervous system helps form the basis for the neurobiology of learning and memory. Long-term potentiation (LTP) is the main form of synaptic plasticity, reflecting the activity level of the synaptic information storage process, and provides a good model to study the underlying mechanisms of learning and memory. The glutamate receptor-mediated signal pathway plays a key role in the induction and maintenance of LTP, and hence the regulation of learning and memory. The progress in the understanding of the glutamate receptors and related signal transduction systems in learning and memory research are reviewed in this article.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Peng S,Zhang Y,Zhang J,Wang H,Ren Bdoi
10.1007/s11033-010-0128-9subject
Has Abstractpub_date
2011-01-01 00:00:00pages
453-60issue
1eissn
0301-4851issn
1573-4978journal_volume
38pub_type
杂志文章,评审abstract::Despite advantageous antitumor properties of doxorubicin, the considerable cytotoxicity of this chemotherapeutic agent has made it necessary to develop combination treatment strategies. The aim of the current study was to investigate the possible synergism between dendrosomal nanocurcumin (DNC) and doxorubicin in elic...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-017-4115-2
更新日期:2017-08-01 00:00:00
abstract::We investigated phenotypic variations for pod shattering, pod length and number of seeds per pod in large germplasm collections of Brassica juncea (2n = 36; AABB) and its progenitor species, B. rapa (2n = 20; AA) and B. nigra (2n = 16; BB). Pod shatter resistance was measured as energy required for rupturing a mature ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05384-9
更新日期:2020-04-01 00:00:00
abstract::Chemerin, as a new member of adipokines family, is highly expressed in adipose tissue in rodent and its expression increases with obesity. Moreover, chemerin has been reported to have significant relationship with metabolic syndrome and insulin sensitivity. Here, the gene encoding chemerin from Xiang pig was cloned. T...
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pub_type: 杂志文章
doi:10.1007/s11033-011-0934-8
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abstract::Two DREB-like genes, designated as DmDREBa and DmDREBb, were isolated from chrysanthemum by RACE approach. The DmDREBa and DmDREBb genes encoded proteins of 191 and 185 amino acid residues with the predicted molecular mass of 21.66 and 20.99 kDa, respectively. Both DmDREBs proteins comprised a typical EREBP/AP2 domain...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-007-9153-8
更新日期:2009-01-01 00:00:00
abstract::Curcumin is a polyphenolic bioactive compound found in the spice turmeric endowed with diverse pharmacological and biological activities. In this study, fluorescence spectroscopy in combination with UV-Vis absorbance spectroscopy was employed to investigate the high affinity binding of curcumin to herring sperm DNA (h...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-013-2530-6
更新日期:2013-07-01 00:00:00
abstract::To investigate whether Annexin 1 can protect a retinal ganglion cells line (RGC-5) from apoptosis as induced by serum deprivation. Annexin 1 location in RGC-5 cells was determined using an indirect immunofluorescent assay. Expression of Annexin 1 in RGC-5 cultures deprived of serum for 0, 2 days was semi-quantified by...
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pub_type: 杂志文章
doi:10.1007/s11033-011-1358-1
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pub_type: 杂志文章
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abstract::Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05042-9
更新日期:2019-12-01 00:00:00
abstract::Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1905-4
更新日期:2012-12-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05683-1
更新日期:2020-08-01 00:00:00
abstract::A culture-independent molecular phylogenetic analysis was carried out to study for the first time the diversity of bacterial ammonia monooxygenase subunit A (amoA) and nitrogenase reductase subunit H (nifH) genes from Urca inlet at Guanabara Bay in Rio de Janeiro, Brazil. Most bacterial amoA and nifH sequences exhibit...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1111-9
更新日期:2012-04-01 00:00:00
abstract::Overexpression of ATP-binding cassette (ABC) transporters causing multidrug resistance (MDR) in cancer cells is one of the major obstacles in cancer chemotherapy. The 5-FU resistant subclone (HL-60/5FU) of the human HL-60 promyelocytic leukemia cell line was selected by the conventional method of continuous exposure o...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-05017-w
更新日期:2019-12-01 00:00:00
abstract::It has been suggested that the allele frequency of thrombophilic mutations is affected by glucose-6-phosphate dehydrogenase (G6PD) deficiency. The prevalence of thrombophilic mutations were studied in sixty G6PD deficient individuals including 57 males and three females with the mean age of 15 +/- 3.08 and 110 age and...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-009-9458-x
更新日期:2009-11-01 00:00:00
abstract::The Editor-in-Chief has decided to retract this article [1]. The article shows significant overlap with two prior publications by the same authors [2, 3], without providing the due citation and attribution. ...
journal_title:Molecular biology reports
pub_type: 已发布勘误,撤回出版物
doi:10.1007/s11033-019-04760-4
更新日期:2019-10-01 00:00:00
abstract::Various case-control studies have shown association of single nucleotide polymorphism rs12303764(G/T) in ULK1 with crohn's disease. The techniques used in these studies were time consuming, complicated and require sophisticated/expensive instruments. Therefore, in order to overcome these problems, we have developed a ...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-016-4087-7
更新日期:2017-02-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-9984-6
更新日期:2011-06-01 00:00:00
abstract::Blood and liver from curimbata (Prochilodus lineatus) acclimated at pH 4.5, 7.0 and 8.0 and at 20 and 30 °C were exposed in vitro to different concentrations of copper (Cu): 98 ± 0.8 μg Cu L-1 at pH 4.5 and 16 ± 0.2 μg Cu L-1 at pH 8.0 at 20 °C; 88 ± 0.8 μg Cu L-1 at pH 4.5 and 14 ± 0.5 μg Cu L-1 at pH 8.0 at 30 °C an...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-019-04944-y
更新日期:2019-10-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章,评审
doi:10.1023/a:1006916206260
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-020-05524-1
更新日期:2020-08-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-014-3173-y
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journal_title:Molecular biology reports
pub_type: 杂志文章
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更新日期:1981-11-30 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-015-3925-3
更新日期:2015-11-01 00:00:00
abstract::Cell free protein synthesis has become a powerful method for the high-throughput production of proteins that are difficult to express in living cells. The protein SAP2 of Fasciola hepatica (FhSAP2), which has demonstrated to be both, an excellent vaccine candidate against experimental fascioliasis and a good antigen f...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-018-4251-3
更新日期:2018-10-01 00:00:00
abstract::The complete mitochondrial genome of Zhikong scallop Chlamys farreri is 21,695 bp in length and contains 12 protein-coding genes (the atp8 gene is absent, as in most bivalves), 2 ribosomal RNA genes, and 22 transfer RNA genes. The heavy strand has an overall A+T content of 58.7%. GC and AT skews for the mt genome of C...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-010-9974-8
更新日期:2011-06-01 00:00:00
abstract::The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-012-1915-2
更新日期:2012-12-01 00:00:00
abstract::A chromosomal fragment containing purA, the nearest marker from the replication origin of the Bacillus subtilis chromosome, was highly purified as a complex containing at least proteins and being solubilized easily during cell lysis. The complex had a markedly higher sedimentation rate (70-120S) than the bulk of the s...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00356932
更新日期:1976-07-01 00:00:00
abstract::The oriental fruit moth, Grapholita molesta (Busck) (Lepidoptera: Tortricidae) currently is one of the economically most destructive pest species of stone and pome fruits worldwide. Here we sequenced the complete mitochondrial genome of this pest. This genome is 15,776 bp long, with an A + T content of 81.24%, contain...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/s11033-011-1049-y
更新日期:2012-03-01 00:00:00
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journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00777498
更新日期:1979-05-31 00:00:00
abstract::A double-stranded RNA-specific nuclease (ds RNase) has been isolated and partially purified from human placenta by DEAE-cellulose and DNA-cellulose column chromatography. Denatured DNA-cellulose retained most of the single-stranded RNA-specific nuclease (ss RNase) activity, whereas the ds RNase came out in the void vo...
journal_title:Molecular biology reports
pub_type: 杂志文章
doi:10.1007/BF00775365
更新日期:1983-08-01 00:00:00
abstract::The aim of this study was to explore candidate single nucleotide polymorphisms (SNPs) and candidate mechanisms of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Two SLE genome-wide association studies (GWASs) datasets were included in this study. Meta-analysis was conducted using 737,984 SNPs in 1,5...
journal_title:Molecular biology reports
pub_type: 杂志文章,meta分析
doi:10.1007/s11033-012-1952-x
更新日期:2012-12-01 00:00:00