Molecular characterization and expression analysis of beta2-microglobulin in large yellow croaker Pseudosciaena crocea.

abstract：:Based on the internal transcribed spacer and inter-simple sequence repeats (ISSR), the phylogenetic relationship and genetic diversity of Metarhizium spp., pathogens found in Chinese burrower bugs, Schiodtella formosana, were analyzed. The results showed that the causative agents of the epizootic green muscardine dise...

journal_title：Molecular biology reports

authors： Luan F,Zhang S,Wang B,Huang B,Li Z

更新日期：2013-01-01 00:00:00

abstract：:RACK1 is a crucial scaffold and anchoring protein, which plays a vital role in multiple signaling pathways of tumorigenesis. The aim of the present study was to identify the correlation between expressions of RACK1 and malignant degrees in colorectal carcinoma (CRC) patients. All together 157 CRC patients were enrolle...

journal_title：Molecular biology reports

authors： Jin S,Mu Y,Wang X,Liu Z,Wan L,Xiong Y,Zhang Y,Zhou L,Li L

更新日期：2014-05-01 00:00:00

abstract：:A secretory high-level expression cloning vector designated as pSBC-20 was constructed by inserting a DNA fragment encoding the signal peptide of ompA protein into pBV 220 vector. Any foreign DNA fragment can be inserted into the polylinker cloning sites located after the secretion signal sequence. The cloned foreign ...

journal_title：Molecular biology reports

authors： Li Y,Yan YC,Guo W,Zhao F,Lai J,Koide SS

更新日期：1995-01-01 00:00:00

abstract：:'Molecular sandwiches' composed of two aromatic amino acids separated by a hydrophilic one were found on eleven subspecies of human interferon alpha, on murine interferon alpha 2, and human interferon beta 1. In addition, another type of the sandwiches was found on several species of interferon. This confirms and exte...

journal_title：Molecular biology reports

authors： Inglot AD,Popik W,Piasecki E,Czyrski J

更新日期：1986-01-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:The rapid progress made over the last 10 years in the identification of individual autoantigens and in the localization of the epitopes involved, has resulted in a parallel reduction in the complexity of the antigen required for the detection of autoantibodies. The ability to use synthetic peptides as antigens is a re...

journal_title：Molecular biology reports

authors： Elkon KB

更新日期：1992-06-01 00:00:00

abstract：:Small ubiquitin-like modifier (SUMO) participates in post-translational modification of various target proteins. SUMOylation is an important molecular regulatory mechanism for plants to respond to abiotic stress. In the present study, GmSUMO2 gene was isolated from soybean seedlings for further study because of the hi...

journal_title：Molecular biology reports

authors： Guo J,Wang S,Wang G,Lu R,Wang Y,Guo Y,Ji W

更新日期：2020-05-01 00:00:00

abstract：:One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which encodes the major t...

journal_title：Molecular biology reports

authors： Seven M,Batar B,Unal S,Yesil G,Yuksel A,Guven M

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs24...

journal_title：Molecular biology reports

authors： Sun R,Huang Y,Zhang H,Liu R

更新日期：2013-11-01 00:00:00

abstract：:With an aim at detecting the ultra-low concentration of avian influenza virus (AIV), a highly sensitive hybrid assay based on immunology and polymerase chain reaction was developed. The TopYield microtiter plates were coated with ten-fold serial dilutions of H5N1 subtype AIV ranging from 10 EID(50 )ml(-1)~10(-4) EID(5...

journal_title：Molecular biology reports

authors： Deng MJ,Xiao XZ,Zhang YM,Wu XH,Zhu LH,Xin XQ,Wu DL

更新日期：2011-03-01 00:00:00

abstract：:Master differentiation transcription factors (MDFs) play decisive roles in cell lineage commitment and cellular functions. Forkhead box P3 (Foxp3) is the MDF essential for the lineage commitment and the suppression function of regulatory T cells (Tregs), which play critical roles in suppression of autoimmunity. Here, ...

journal_title：Molecular biology reports

authors： Fujita T,Fujii H

更新日期：2012-10-01 00:00:00

abstract：:The lysyl oxidase-like 2 (LOXL2) protein is a human paralogue of lysyl oxidase (LOX) that functions as an amine oxidase for formation of lysine-derived cross-links found in collagen and elastin. In addition to the C-terminal domains characteristic to the LOX family members, LOXL2 contains four scavenger receptor cyste...

journal_title：Molecular biology reports

authors： Kim YM,Kim EC,Kim Y

更新日期：2011-01-01 00:00:00

abstract：:Various efforts made to stop the deadly epidemic of HIV since its discovery in 1983 remain unsuccessful and this virus still continues to claim the lives of millions of individuals every year. The viral effect in the cell is complicated and the overall disease outcome is the result of interaction between a few viral p...

journal_title：Molecular biology reports

authors： Sobti RC,Berhane N,Mehedi SA,Kler R,Hosseini SA,Kuttiat V,Wanchu A

更新日期：2010-01-01 00:00:00

abstract：:Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple neoplasms. The main purpose of this study was to investigate the expression of these miRNAs in bladder cancer (BCa) and to analyze the association between their expression profiles and clinical and epidemiological parameters. Ninety BCa specim...

journal_title：Molecular biology reports

authors： Boubaker NS,Spagnuolo M,Trabelsi N,Said R,Gurtner A,Regazzo G,Ayed H,Blel A,Karray O,Saadi A,Rammeh S,Chebil M,Rizzo MG,Piaggio G,Ouerhani S

更新日期：2020-02-01 00:00:00

abstract：:The myocyte enhancer factor 2C (MEF2C) is a member of the MEF2 family of transcription factors, involved in skeletal muscle development. In this study we report the cDNA sequence and isolate the 5' upstream region of the mef2c gene from porcine genomic DNA using PCR-based GenomeWalker. The open reading frame of porcin...

journal_title：Molecular biology reports

authors： Liu M,Xu DQ,Peng J,Zheng R,Li F,Jiang SW

更新日期：2011-10-01 00:00:00

abstract：:Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that plays an important role in breast cancer pathophysiology and risk definition, since it regulates the bioavailable fraction of circulating estradiol. Epidemiological studies have evaluated the association between SHBG Asp327Asn polymorphism and breast ca...

journal_title：Molecular biology reports

authors： Zhou JY,Shi R,Yu HL,Zheng WL,Ma WL

更新日期：2012-08-01 00:00:00

abstract：:It is widely accepted that protein phosphorylation is a major control event in regulating cell cycle. In the present study, a novel M-phase phosphoprotein 6 (MPP6) was identified from black tiger shrimp Penaeus monodon (designated as PmMPP6) by cDNA library and RACE approaches. The full-length cDNA of PmMPP6 was of 69...

journal_title：Molecular biology reports

authors： Zhou J,Qiu L,Jiang S,Zhou F,Huang J,Yang L,Su T,Zhang D

更新日期：2013-02-01 00:00:00

abstract：:LNX (Ligand of Numb-protein X) was originally isolated as a binding partner to the cell-fate Determinant Numb during development, and then identified to act as a RING finger-type E3 ubiquitin ligase for the ubiquitylation and degradation of Numb. LNX contains 4 PDZ domains which are proved to play a central role in or...

journal_title：Molecular biology reports

authors： Zheng D,Sun Y,Gu S,Ji C,Zhao W,Xie Y,Mao Y

更新日期：2010-06-01 00:00:00

abstract：:Gibberellic acid (GA) is involved in the regulation of plant growth and development. We defined GA-stimulated transcript (GAST) gene family and characterized its four members (TaGAST1, 2, 3, and 4) in wheat spikes. Triticum aestivum whole spikes were collected at ten developmental stages and dehulled spikelets were ob...

journal_title：Molecular biology reports

authors： Kim YJ,Kim JY,Yoon JS,Kim DY,Hong MJ,Seo YW

更新日期：2016-12-01 00:00:00

abstract：:Overexpression of differentiated embryo chondrocyte 1 (DEC1) has been reported to contribute to the cellular differentiation, proliferation, and apoptosis of various cancers. Our previous studies have shown that DEC1 was highly expressed in gastric cancer (GCa) tissues. However, there is no report about the expression...

journal_title：Molecular biology reports

authors： Zheng Y,Shi X,Wang M,Jia Y,Li B,Zhang Y,Liu Q,Wang Y

更新日期：2012-04-01 00:00:00

abstract：:Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an ex...

journal_title：Molecular biology reports

authors： Gismondi A,Nanni V,Monteleone V,Colao C,Di Marco G,Canini A

更新日期：2021-01-01 00:00:00

abstract：:The MinION is a miniaturized high-throughput next generation sequencing platform of novel conception. The use of nucleic acids derived from formalin-fixed paraffin-embedded samples is highly desirable, but their adoption for molecular assays is hurdled by the high degree of fragmentation and by the chemical-induced mu...

journal_title：Molecular biology reports

authors： Vacca D,Cancila V,Gulino A,Lo Bosco G,Belmonte B,Di Napoli A,Florena AM,Tripodo C,Arancio W

更新日期：2018-02-01 00:00:00

abstract：:Metabolic syndrome is an agglomeration of disorders including obesity, diabetes and cardiovascular diseases and characterized as chronic mild inflammation which elevates the circulatory inflammatory markers. This could be due to mitochondrial dysfunction, oxidative stress and hypoxia as a consequence of high fat diet ...

journal_title：Molecular biology reports

authors： Jha D,Mitra Mazumder P

更新日期：2019-04-01 00:00:00

abstract：:Studies investigating the association between glutathione S-transferase M1 (GSTM1) polymorphism and bladder cancer risk report conflicting results. The objective of this study was to quantitatively summarize the evidence for such a relationship. We performed a systematic search of the National Library of Medline and E...

journal_title：Molecular biology reports

authors： Zhang R,Xu G,Chen W,Zhang W

更新日期：2011-04-01 00:00:00

abstract：:Lac insects are commercial scale insects with high economic value. The combined molecular phylogeny of 20 lac insect populations was generated using elongation factor 1 alpha, mitochondrial cytochrome c oxidase subunit I and the small subunit ribosomal RNA gene loci. The 20 populations of lac insects clustered into fo...

journal_title：Molecular biology reports

authors： Chen H,Chen X,Feng Y,Yang H,He R,Zhang W,Yang Z

更新日期：2013-10-01 00:00:00

abstract：:Protein phosphorylation is one of the most fundamental types of post-translational modifications and it plays a vital role in various cellular processes of eukaryotes. Among three types of phosphorylation i.e. serine, threonine and tyrosine phosphorylation, tyrosine phosphorylation is one of the most frequent and it i...

journal_title：Molecular biology reports

authors： Khan YD,Rasool N,Hussain W,Khan SA,Chou KC

更新日期：2018-12-01 00:00:00

abstract：:Cartilage has a limited self-repair capability and the repair of large cartilage defects remains a challenge in clinic. This study aimed to investigate the effect of mesenchymal stem cells (MSCs) loaded three-dimensional bilayer collagen scaffold for cartilage repair. Cross-linked three-dimensional bilayer collagen sc...

journal_title：Molecular biology reports

authors： Qi Y,Zhao T,Xu K,Dai T,Yan W

更新日期：2012-02-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00

abstract：:Two GATC specific methylases together with Sau3AI isoschizomeric restriction endonuclease were partially characterized in Mitsuokella multiacida 46/5. This is the first report on the presence of solitary Dam methyltransferase alongside GATC specific restriction-modification system resulting in the unusual two-fold met...

journal_title：Molecular biology reports

authors： Piknova M,Filova M,Javorsky P,Pristas P

更新日期：2005-12-01 00:00:00

abstract：:Long non-coding RNAs (LncRNAs) are non-coding RNAs. The potential roles of lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to assess the expression levels of LY86-AS1 and HCG27_201 in T2DM patients and a healthy control group. We obtained whole blood and serum samples from 100 T2DM...

journal_title：Molecular biology reports

authors： Saeidi L,Ghaedi H,Sadatamini M,Vahabpour R,Rahimipour A,Shanaki M,Mansoori Z,Kazerouni F

更新日期：2018-12-01 00:00:00