The restoration of full-thickness cartilage defects with mesenchymal stem cells (MSCs) loaded and cross-linked bilayer collagen scaffolds on rabbit model.

abstract：:An improvement in the detection by nucleic acid hybridization of size-fractionated RNA immobilized to nylon-based membranes is described. Electrophoretic transfer of RNA to nylon membranes permits a quantitative determination of different RNA transcripts on the same membrane after sequential hybridization using differ...

journal_title：Molecular biology reports

authors： Khandjian EW

更新日期：1986-01-01 00:00:00

abstract：:Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associat...

journal_title：Molecular biology reports

authors： Vasconcelos GM,Gonçalves BA,Montalvão-de-Azevedo R,Thuler LC,Braga FH,Pombo-de-Oliveira MS,de Camargo B,Brazilian Embryonal Tumor Group.

更新日期：2014-09-01 00:00:00

abstract：:In the present study, root cell suspension cultures of W. somnifera were elicited with mycelial extract (1% w/v) and culture filtrate (5% v/v) of their native endophytic fungus Aspergillus terreus 2aWF in shake flask. Culture filtrate of A. terreus 2aWF significantly elicits withanolide A at 6H (12.20 ± 0.52 µg/g FCB)...

journal_title：Molecular biology reports

authors： Kushwaha RK,Singh S,Pandey SS,Kalra A,Vivek Babu CS

更新日期：2019-04-01 00:00:00

abstract：:Etiological factors for coronary artery disease (CAD) involve a wide range of gene and environmental interactions. One of the systems being implicated in the pathophysiology of CAD is the renin-angiotensin system (RAS). However, the genetic polymorphisms of this system have not been widely studied in Iranian patients ...

journal_title：Molecular biology reports

authors： Firouzabadi N,Tajik N,Bahramali E,Bakhshandeh H,Maadani M,Shafiei M

更新日期：2013-08-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:Variants of the transcription factor 7-like 2 gene (TCF7L2) have been associated with type 2 diabetes and cardiovascular disease in different populations. Here we investigated the potential association of the rs7903146 polymorphism in the TCF7L2 gene with clinical profile of end-stage renal disease (ESRD) patients. We...

journal_title：Molecular biology reports

authors： Buraczynska M,Zukowski P,Ksiazek P,Kuczmaszewska A,Janicka J,Zaluska W

更新日期：2014-06-01 00:00:00

abstract：:Heavy metals pollution affects the nutritive value of fish. This study examined if the inclusion of dietary hempseed (HS) and hempseed oil (HO) in the diet of the fish could revert the copper-induced toxic effects on muscle fatty acid profile of rohu (Labeo rohita) and mrigal (Cirrhinus mrigala). Fingerlings of both s...

journal_title：Molecular biology reports

authors： Afridi AJ,Zuberi A,Yousafzai AM,Maria,Kamran M,Ullah S

更新日期：2019-02-01 00:00:00

abstract：:Syndecan-1 has been implicated in tumorigenesis and progression of various human malignancies. Recent studies have demonstrated that syndecan-1 may have a different function and biological activity depending on the specific tumor type. Therefore, the aim of this study was to investigate the clinical significance of sy...

journal_title：Molecular biology reports

authors： Xu Y,Yuan J,Zhang Z,Lin L,Xu S

更新日期：2012-09-01 00:00:00

abstract：:The plasticity of the central nervous system helps form the basis for the neurobiology of learning and memory. Long-term potentiation (LTP) is the main form of synaptic plasticity, reflecting the activity level of the synaptic information storage process, and provides a good model to study the underlying mechanisms of...

journal_title：Molecular biology reports

authors： Peng S,Zhang Y,Zhang J,Wang H,Ren B

更新日期：2011-01-01 00:00:00

abstract：:MAPK cascade is an important intracellular signaling module and function as a convergent point for crosstalk during abiotic stress signaling. In this study SbMAPKK gene has been isolated from Salicornia brachiata, a highly salt tolerant plant growing in costal marshes of Gujarat, India. The SbMAPKK gene is 1,023 bp lo...

journal_title：Molecular biology reports

authors： Agarwal PK,Gupta K,Jha B

更新日期：2010-02-01 00:00:00

abstract：:One mutant transgenic line displaying homeotic conversion of sepals to petals with other phenotypic aberrations was selected and characterized at molecular level. The increased transcript level of gene encoding anthocyanidin synthase and petal specific class B genes, GLOBOSA and DEFECIENS in sepals of mutant line may ...

journal_title：Molecular biology reports

authors： Mahajan M,Yadav SK

更新日期：2014-02-01 00:00:00

abstract：:Polyomavirus JC (JCPyV) is a ubiquitous human neurotropic virus that can cause progressive multifocal leukoencephalopathy (PML), sometimes as a consequence of drug treatment for disabling diseases, including Multiple Sclerosis. JCPyV expresses microRNAs (miRNAs), and in particular miR-J1-5p, but at now we have limited...

journal_title：Molecular biology reports

authors： Agostini S,Mancuso R,Costa AS,Guerini FR,Clerici M

更新日期：2020-11-01 00:00:00

abstract：:The glutathione S-transferase (GST) family of enzymes is known to play a pivotal role in phase II of biotransformation of xenobiotics, environmental carcinogens and pharmacological drugs. The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstru...

journal_title：Molecular biology reports

authors： Thakur H,Gupta L,Sobti RC,Janmeja AK,Seth A,Singh SK

更新日期：2011-03-01 00:00:00

abstract：:Cytokinin oxidases are involved in the regulation of plant cytokinin levels, which are important in regulating plant growth and development, and may affect the yield of cereals. Here, we report the isolation and characterization of two putative cytokinin oxidase genes, TaCKX2.1 and TaCKX2.2, from wheat. Both TaCKX2.1 ...

journal_title：Molecular biology reports

authors： Zhang J,Liu W,Yang X,Gao A,Li X,Wu X,Li L

更新日期：2011-04-01 00:00:00

abstract：:In this study, we cloned and sequenced genomic sequences from a Fenneropenaeus chinensis transcriptional repressor gene, FcTR. The FcTR gene is 2,671 bp in length and has four exons and three introns. The 873 bp promoter contains several transcription factor binding sites, including a TATA box and a cyclic AMP-respons...

journal_title：Molecular biology reports

authors： Lai X,Shen S,Gao H,Yan B

更新日期：2015-02-01 00:00:00

abstract：:The cytotoxic T lymphocyte-associated antigen 4 gene (CTLA4) has a crucial role in regulation of T cell proliferation and mediates T cell apoptosis by encoding the T cell receptor. Schizophrenia (SCZ) patients often have abnormalities in terms of the function and development of the immune system. The aim of the presen...

journal_title：Molecular biology reports

authors： Kordi-Tamandani DM,Vaziri S,Dahmardeh N,Torkamanzehi A

更新日期：2013-08-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:We report here a cDNA and its deduced amino acid sequence encoding a cathepsin D-like, aspartic protease from Chlamys farreri (denoted as CfCD) by expressed sequence tag and rapid amplification of cDNA ends techniques. The cDNA of CfCD consisted of 1,810 nucleotides with a canonical polyadenylation signal sequence AAT...

journal_title：Molecular biology reports

authors： Li C,Zhang H,Li L,Song L

更新日期：2010-03-01 00:00:00

abstract：:Experimental evidence highlights the importance of dietetic factors on breast cancer. In this work we aimed to analyze the effects two oils, corn oil (rich in n-6 polyunsaturated fatty acids -PUFA-) and extra virgin olive oil (EVOO), on oxidative stress in an animal model of breast carcinogenesis. Female rats were fed...

journal_title：Molecular biology reports

authors： Escrich R,Vela E,Solanas M,Moral R

更新日期：2020-07-01 00:00:00

abstract：:Cytochrome P450 1B1 (CYP1B1) is a key P450 enzyme involved in the metabolism of exogenous and endogenous substrates in endocrine-mediated tumors such as prostate cancer. The potential significance of nonsynonymous SNP Leu432Val (rs1056836) as a risk factor in prostate cancer has been extensively studied. The objective...

journal_title：Molecular biology reports

authors： Cui L,Dillehay K,Chen W,Shen D,Dong Z,Li W

更新日期：2012-07-01 00:00:00

abstract：:Of the only known two Lagoon populations of Irrawaddy dolphins (Orcaella) in the world, one is residing in the Chilika Lagoon in Orissa state, India. In addition to accidental deaths in gill net fishery and mechanized boat operations, there has been exploitation of the species for their oil. Extreme patchy distributio...

journal_title：Molecular biology reports

authors： Jayasankar P,Patel A,Khan M,Das P,Panda S

更新日期：2011-03-01 00:00:00

abstract：:Small ubiquitin-like modifier (SUMO) participates in post-translational modification of various target proteins. SUMOylation is an important molecular regulatory mechanism for plants to respond to abiotic stress. In the present study, GmSUMO2 gene was isolated from soybean seedlings for further study because of the hi...

journal_title：Molecular biology reports

authors： Guo J,Wang S,Wang G,Lu R,Wang Y,Guo Y,Ji W

更新日期：2020-05-01 00:00:00

abstract：:Current study was conducted to investigation of effect of magnetic field on cell dedifferentiation and follow it callus induction derived from mature embryo culture in bread wheat genotypes. For this purpose, a factorial experiment based on completely randomized design was carried out with two wheat genotypes and thre...

journal_title：Molecular biology reports

authors： Kahrizi D,Cheghamirza K,Akbari L,Rostami-Ahmadvandi H

更新日期：2013-02-01 00:00:00

abstract：:Long-term ketamine abuse is known to affect the lower urinary tract and produce symptoms of cystitis. However, the pathophysiology and causative mechanism of the changes in bladder function remain unclear. The present study aimed to investigate the existence of ketamine-induced cystitis in a rat model and characterize...

journal_title：Molecular biology reports

authors： Gu D,Huang J,Yin Y,Shan Z,Zheng S,Wu P

更新日期：2014-11-01 00:00:00

abstract：:Selenium compounds have been widely investigated as novel anticancer agents due to high efficacy and selectivity against cancer cells in recent years. This study aimed to research the potential inhibitory effects of seleno-β-lactoglobulin (Se-β-Lg) on HepG2 cells in vitro. MTT results demonstrated that the synthetized...

journal_title：Molecular biology reports

authors： Ji HY,Yu J,Liu AJ

更新日期：2019-10-01 00:00:00

abstract：:A secretory high-level expression cloning vector designated as pSBC-20 was constructed by inserting a DNA fragment encoding the signal peptide of ompA protein into pBV 220 vector. Any foreign DNA fragment can be inserted into the polylinker cloning sites located after the secretion signal sequence. The cloned foreign ...

journal_title：Molecular biology reports

authors： Li Y,Yan YC,Guo W,Zhao F,Lai J,Koide SS

更新日期：1995-01-01 00:00:00

abstract：:India has a rich heritage of rearing cattle where farmers selected native cattle suitable to their local agro-ecological conditions for centuries. It is reflected in 50 indigenous breeds of cattle, besides many lesser known populations not explored so far. It is the need of the hour to characterize such populations to...

journal_title：Molecular biology reports

authors： Sharma R,Ahlawat S,Sharma H,Bhagat RL,Singh PK,Tantia MS

更新日期：2020-08-01 00:00:00

abstract：:A copper(II) complex containing aspartame (APM) as ligand, Cu(APM)2Cl2·2H2O, was synthesized and characterized. In vitro binding interaction of this complex with human serum albumin (HSA) was studied at physiological pH. Binding studies of this complex with HSA are useful for understanding the Cu(APM)2Cl2·2H2O-HSA int...

journal_title：Molecular biology reports

authors： Shahabadi N,Khodaei MM,Kashanian S,Kheirdoosh F,Filli SM

更新日期：2014-05-01 00:00:00

abstract：:Uterine leiomyomas (UL) are prevalent benign tumors, especially among women of African ancestry. The disease also has genetic liability and is influenced by risk factors such as hormones and obesity. This study investigates the haplotypes of the Cytochrome P450 1B1 gene (CYP1B1) related to hormones and coiled-coil dom...

journal_title：Molecular biology reports

authors： Alleyne AT,Bideau VS

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this study was to identify genomic regions, quantitative trait loci (QTL), affecting carcass traits on chromosome 1 in an F2 population of Japanese quail. For this purpose, two white and wild strains of Japanese quail (16 birds) were crossed reciprocally and F1 generation (34 birds) was created. The F2 ...

journal_title：Molecular biology reports

authors： Moradian H,Esmailizadeh AK,Sohrabi SS,Nasirifar E,Askari N,Mohammadabadi MR,Baghizadeh A

更新日期：2014-07-01 00:00:00