Gain of function mutation in tobacco MADS box promoter switch on the expression of flowering class B genes converting sepals to petals.

abstract：:RNA polymerase III in an extract of HeLa cells transcribes RNA 5S in size from genomic bovine DNA template. This RNA represents a major fraction of the RNA synthesized. 5S RNA is not transcribed from bovine chromatin at equivalent concentrations and RNA the size of tRNA or tRNA precursor is not detected. At low UTP co...

journal_title：Molecular biology reports

authors： Furth JJ,Su CY

更新日期：1983-08-01 00:00:00

abstract：:Amerindians immigrated to Madrid (Spain) region are about 10% of the present day population. Amerindians are believed to be the first American inhabitants, before Na-Dene speakers, Aleuts and Eskimo. They may initially have arrived to America from Siberia and also from other parts of Pacific Sea (South Asia, Polynesia...

journal_title：Molecular biology reports

authors： Parga-Lozano C,Rey-Medrano D,Gomez-Prieto P,Areces C,Moscoso J,Abd-El-Fatah-Khalil S,Moreno E,Arnaiz-Villena A

更新日期：2011-04-01 00:00:00

abstract：:DNA-, RNA- and protein synthesis have been studied in Mycobacterium smegmatis cells infected with phage I3. The macromolecular synthesis continued until the end of latent period. Early RNA and protein synthesis were necessary prior to the commencement of DNA replication. The infecting phage DNA sedimented as larger th...

journal_title：Molecular biology reports

authors： Nagaraja V,Gopinathan KP

更新日期：1981-11-30 00:00:00

abstract：:It has been suggested that the estrogen receptor alpha (ERα) and vitamin D receptor (VDR) genes as possibly implicated in reduced bone mineral density (BMD) in osteoporosis. The present study investigated the relation of ERα PvuII/XbaI polymorphisms and VDR FokI/TaqI polymorphisms with BMD in Turkish postmenopausal wo...

journal_title：Molecular biology reports

authors： Kurt O,Yilmaz-Aydogan H,Uyar M,Isbir T,Seyhan MF,Can A

更新日期：2012-06-01 00:00:00

abstract：:In the post-genomic era, providing a detailed description of protein functions poses a formidable challenge. To gain functional insights, we have to construct many kinds of expression vectors. DNA recombination based on polymerase chain reaction (PCR) and digestion followed by ligation is the preferred method for vect...

journal_title：Molecular biology reports

authors： Pan JS,Zhang ZP,Cai JY,Dong J,Ren JL,Wang XZ

更新日期：2010-03-01 00:00:00

abstract：:We investigated phenotypic variations for pod shattering, pod length and number of seeds per pod in large germplasm collections of Brassica juncea (2n = 36; AABB) and its progenitor species, B. rapa (2n = 20; AA) and B. nigra (2n = 16; BB). Pod shatter resistance was measured as energy required for rupturing a mature ...

journal_title：Molecular biology reports

authors： Kaur J,Akhatar J,Goyal A,Kaur N,Kaur S,Mittal M,Kumar N,Sharma H,Banga S,Banga SS

更新日期：2020-04-01 00:00:00

abstract：:The investigation was carried out to analyse the genetic polymorphism and gene expression of ATP1A1 gene in four different Indian goat breeds by using high resolution melting (HRM) and real time-PCR. ATPase is electro-genic ion pump which is maintains the balance of sodium and potassium ions in animal cells. The trans...

journal_title：Molecular biology reports

authors： Kaushik R,Goel A,Rout PK

更新日期：2019-10-01 00:00:00

abstract：:Selenium compounds have been widely investigated as novel anticancer agents due to high efficacy and selectivity against cancer cells in recent years. This study aimed to research the potential inhibitory effects of seleno-β-lactoglobulin (Se-β-Lg) on HepG2 cells in vitro. MTT results demonstrated that the synthetized...

journal_title：Molecular biology reports

authors： Ji HY,Yu J,Liu AJ

更新日期：2019-10-01 00:00:00

abstract：:Molecular detection of Giardia duodenalis by polymerase chain reaction (PCR) is difficult in faecal samples due to inhibitors that contaminate DNA preparations, or due to low cyst concentrations. In order to eliminate inhibitors, improve cyst recovery and molecular detection of G. duodenalis, different types of water,...

journal_title：Molecular biology reports

authors： Bezagio RC,Colli CM,Romera LIL,de Almeida CR,Ferreira ÉC,Mattia S,Gomes ML

更新日期：2020-02-01 00:00:00

abstract：:Ventricular assist devices may function as a bridge to recovery or heart transplantation, however, little is known about its mechanisms. This study examined the role of matrix metalloproteinases (MMP)-tissue inhibitors of metalloproteinases (TIMP) axis in the process of recovery after unloading in a rat ischemic-induc...

journal_title：Molecular biology reports

authors： Wang WJ,Meng ZL,Mo YC,Liu JW,Sun CC,Hu SS,Zhang H

更新日期：2012-01-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:The occurrence of PFD is closely related with elasticity, toughness, and functional changes of the connective tissue of the pelvic support tissue. This study aims to evaluate the effect of mechanical stretch on the differentiation of BMSCs with a co-culture with pelvic ligament fibroblasts. BMSCs was isolated and iden...

journal_title：Molecular biology reports

authors： Bing Z,Linlin L,Jianguo Y,Shenshen R,Ruifang R,Xi Z

更新日期：2012-05-01 00:00:00

abstract：:Many environmental and genetic factors have been contributed to the development of systemic sclerosis (SSc). To determine whether IL-10 gene polymorphisms are associated with SSc, we conducted a meta-analysis approach. A total of eight studies involving 1,034 SSc cases and 1,815 controls were obtained by electronic da...

journal_title：Molecular biology reports

authors： Peng WJ,Wang BX,Pan HF,Tao JH,Zhang JQ,He Q,Xiao CC,Wang J

更新日期：2012-06-01 00:00:00

abstract：:Quercus acutissima is native to eastern Asia. It has a wide distribution in China and China is an important component in understanding the ecology and genetic structure of this species. Q. acutissima attained high economic value for hardwood product and can be managed as an energy tree species. To investigate the gene...

journal_title：Molecular biology reports

authors： Zhang YY,Fang YM,Yu MK,Li XX,Xia T

更新日期：2013-06-01 00:00:00

abstract：:The relationship between genetic polymorphisms of glutathione S-transferase (GST) and the development of glioma has been investigated in several epidemiologic studies. However these studies report inconsistent results. In order to quantitatively summarise the evidence for such a relationship, a meta-analysis is conduc...

journal_title：Molecular biology reports

authors： Fan Z,Wu Y,Shen J,Zhan R

更新日期：2013-02-01 00:00:00

abstract：:Transition from laying to incubation behavior in chicken is an interesting topic in reproductive biology. The decline of incubation behavior in chicken population has led to considerable phenotypic differences in reproductive traits between breeds. However, the exact genetic mechanism of the reproductive phase transit...

journal_title：Molecular biology reports

authors： Shen X,Bai X,Xu J,Zhou M,Xu H,Nie Q,Lu X,Zhang X

更新日期：2016-09-01 00:00:00

abstract：:Neuroinflammation affects millions of people around the world as a result of injury or stress. Neuroinflammation represents almost all types of neurological diseases such as multiple sclerosis and Alzheimer's disease. Neurodegenerative diseases comprise demyelination and synaptic loss. The inflammatory response is fur...

journal_title：Molecular biology reports

authors： Siddiqui S,Kamal A,Khan F,Jamali KS,Saify ZS

更新日期：2019-02-01 00:00:00

abstract：:Vascular endothelial growth factor B (VEGF-B) was reported to be angiogenic, and it was considered as a neuroprotective agent in mouse retinal ganglion cells following optic nerve crush. Thus, it was necessary to investigate whether VEGF-B contributes to the process of retinal and choroidal neovascularization. We aime...

journal_title：Molecular biology reports

authors： Zhang GH,Qin R,Zhang SH,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium lat...

journal_title：Molecular biology reports

authors： Sinha VB,Grover A,Singh S,Pande V,Ahmed Z

更新日期：2014-09-01 00:00:00

abstract：:Transcription factor RBP-J-mediated Notch signaling has been implicated in several inherited cardiovascular diseases including aortic valve diseases (AVD). But whether Notch signal plays a role in AVD in adults has been unclear. This study aims to test whether the deletion of RBP-J in adult mice would lead to AVD and ...

journal_title：Molecular biology reports

authors： Li Z,Feng L,Wang CM,Zheng QJ,Zhao BJ,Yi W,Zhang JZ,Wang YM,Guo HT,Yi DH,Han H

更新日期：2012-04-01 00:00:00

abstract：:Epidemiological studies found inconsistent results on the association of two variants on TGFBR1 (TGFBR1*6A and Int7G24A) with colorectal cancer (CRC) risk. The present study was aimed to evaluate the association of these two variants with CRC susceptibility via the meta-analysis methods. For variant TGFBR1*6A, nine re...

journal_title：Molecular biology reports

authors： Zhang X,Wu L,Sheng Y,Zhou W,Huang Z,Qu J,Gao G,Cai D,Zhang M

更新日期：2012-03-01 00:00:00

abstract：:Cellular cholesterol homeostasis is controlled by the sterol-regulatory element binding transcription factors (SREBFs) that are activated by an SREBF cleavage-activating protein (SCAP). SREBF-2 1784G > C single nucleotide polymorphism (SNP, rs2228314) and SCAP 2386A > G variant (rs12487736) are associated with early o...

journal_title：Molecular biology reports

authors： Chen Z,Ding Z,Ma G,Liu N,Qian Q

更新日期：2011-06-01 00:00:00

abstract：:Honey bee is important economic insect that not only pollinates fruits and crops but also provides products with various physiological activities. Bee venom is a functional agent that is widely applied in clinical treatment and pharmacy. Secapin is one of these agents that have a significant role in therapy. The funct...

journal_title：Molecular biology reports

authors： Hou C,Guo L,Lin J,You L,Wu W

更新日期：2014-12-01 00:00:00

abstract：:MADS-box genes encode important transcription factors in plants that are involved in many processes during plant growth and development. An investigation of the soybean genome revealed 106 putative MADS-box genes. These genes were classified into two classes, type I and type II, based on phylogenetic analysis. The soy...

journal_title：Molecular biology reports

authors： Shu Y,Yu D,Wang D,Guo D,Guo C

更新日期：2013-06-01 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：:Toll-like receptors (TLRs) constitute a multi-gene family, which plays a pivotal role in sensing invading pathogens by virtue of conserved microbial patterns. TLR repertoire of chicken and zebra finch has been well studied. However TLR family of other avian species is yet to be characterized. In the present study, we ...

journal_title：Molecular biology reports

authors： Ramasamy KT,Reddy MR,Verma PC,Murugesan S

更新日期：2012-08-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR) polymorphism may play an important role in the pathophysiology of obesity and diabetes accompanied by obesity due to its influence on plasma homocysteine levels. There are significant and sometimes very strong relationship between levels of homocysteine and several multi-sys...

journal_title：Molecular biology reports

authors： Tavakkoly Bazzaz J,Shojapoor M,Nazem H,Amiri P,Fakhrzadeh H,Heshmat R,Parvizi M,Hasani Ranjbar S,Amoli MM

更新日期：2010-01-01 00:00:00

abstract：:The purpose of this study was to identify genomic regions, quantitative trait loci (QTL), affecting carcass traits on chromosome 1 in an F2 population of Japanese quail. For this purpose, two white and wild strains of Japanese quail (16 birds) were crossed reciprocally and F1 generation (34 birds) was created. The F2 ...

journal_title：Molecular biology reports

authors： Moradian H,Esmailizadeh AK,Sohrabi SS,Nasirifar E,Askari N,Mohammadabadi MR,Baghizadeh A

更新日期：2014-07-01 00:00:00

abstract：:The molecular composition of macromolecular assemblies engaged in transcription and splicing influences biogenesis of mRNA transcripts. Preference for one over the other interactive protein partner within those complexes is expected to change the gene expression pattern and to affect subsequent cellular events. We rep...

journal_title：Molecular biology reports

authors： Marko M,Leichter M,Patrinou-Georgoula M,Guialis A

更新日期：2014-01-01 00:00:00

abstract：:1-Deoxynojirimycin (DNJ), the main alkaloid in mulberry leaves, was recognized to treat patients with type 2 diabetes mellitus (T2DM). However, the regulatory mechanism of DNJ on glucose homeostasis was still unclear. In the present study, a safe concentration of 0.1-10 μmol/L for DNJ was incubated with mature 3T3-L1 ...

journal_title：Molecular biology reports

authors： Li Q,Wang Y,Dai Y,Shen W,Liao S,Zou Y

更新日期：2019-12-01 00:00:00