Angiogenic and anti-angiogenic factor gene transcript level quantitation by quantitative real time PCR in patients with hepatocellular carcinoma.

abstract：:Breast cancer is the most common cancer type and the second cause of cancer death in women. Different mechanisms are contributed to the initiation and progression of the breast cancer. OCC-1 and APPL2 neighboring genes located in 12q.23.3 human chromosome region are related to colorectal cancer. Here, we intended to i...

journal_title：Molecular biology reports

authors： Ghalaei A,Kay M,Zarrinfam S,Hoseinpour P,Behmanesh M,Soltani BM

更新日期：2018-12-01 00:00:00

abstract：:The conserved M2 protein of influenza A virus is considered as a promising candidate target for a broad-spectrum, recombinant influenza A vaccine. In the present study, the open reading frame (ORF) of avian influenza A/chicken/Iran/101/1998 (H9N2) M2 gene was amplified then cloned in pAED4, prokaryotic expression vect...

journal_title：Molecular biology reports

authors： Ebrahimi SM,Tebianian M,Aghaiypour K,Nili H,Mirjalili A

更新日期：2010-07-01 00:00:00

abstract：:Vascular endothelial growth factor B (VEGF-B) was reported to be angiogenic, and it was considered as a neuroprotective agent in mouse retinal ganglion cells following optic nerve crush. Thus, it was necessary to investigate whether VEGF-B contributes to the process of retinal and choroidal neovascularization. We aime...

journal_title：Molecular biology reports

authors： Zhang GH,Qin R,Zhang SH,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:In individuals with diabetes, a log linear relationship exists between cholesterol levels and cardiovascular disease. Type 2 diabetes (T2D) and Statins, a cholesterol lowering drug, have a complex relationship. Statins are potent modulators of CYP3A4 2 enzyme and endothelial nitric oxide synthase (eNOS) functions in a...

journal_title：Molecular biology reports

authors： Jamil K,Kandula V,Kandula R,Asimuddin M,Joshi S,Yerra SK

更新日期：2014-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease in which numerous cells and mediators affect inflammatory conditions and disease severity. To compare the serum levels of adiponectin, vitamin D, copper, and zinc in patients with RA and to investigate the relationship between these parameters and RA severity...

journal_title：Molecular biology reports

authors： Khajoei S,Hassaninevisi M,Kianmehr N,Seif F,Khoshmirsafa M,Shekarabi M,Samei A,Haghighi A

更新日期：2019-04-01 00:00:00

abstract：:Syndecan-1 has been implicated in tumorigenesis and progression of various human malignancies. Recent studies have demonstrated that syndecan-1 may have a different function and biological activity depending on the specific tumor type. Therefore, the aim of this study was to investigate the clinical significance of sy...

journal_title：Molecular biology reports

authors： Xu Y,Yuan J,Zhang Z,Lin L,Xu S

更新日期：2012-09-01 00:00:00

abstract：:Two GATC specific methylases together with Sau3AI isoschizomeric restriction endonuclease were partially characterized in Mitsuokella multiacida 46/5. This is the first report on the presence of solitary Dam methyltransferase alongside GATC specific restriction-modification system resulting in the unusual two-fold met...

journal_title：Molecular biology reports

authors： Piknova M,Filova M,Javorsky P,Pristas P

更新日期：2005-12-01 00:00:00

abstract：:Helicteres hirsuta Lour. (H. hirsuta) has been considered as a herbal medicine for the treatment of malaria and diabetes but limited studies have been conducted on its anticancer and antibacterial properties. In this study, the in vitro antibacterial and anticancer properties of the leaf and stem extracts and their tw...

journal_title：Molecular biology reports

authors： Pham HNT,Sakoff JA,Bond DR,Vuong QV,Bowyer MC,Scarlett CJ

更新日期：2018-12-01 00:00:00

abstract：:Previous report showed that Estrogen related receptor α (ERRα) knockout mice had a significant reduction in adipose tissue deposition. Although it was reported that ERRα could promote adipogenesis in several immortalized preadipocytes cell lines, the mechanism behind which is still unclear to date. Besides, the expres...

journal_title：Molecular biology reports

authors： Ju D,He J,Zhao L,Zheng X,Yang G

更新日期：2012-03-01 00:00:00

abstract：:The aim of this study was to determine whether the Fcγ receptors (FCGRs) polymorphisms confer susceptibility to periodontitis in ethnically different populations. We did a literature search using PubMed and Embase, and conducted a meta-analysis on the associations between the FCGR2A H131R (rs1801274), FCGR3A F158V (rs...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:Based on the internal transcribed spacer and inter-simple sequence repeats (ISSR), the phylogenetic relationship and genetic diversity of Metarhizium spp., pathogens found in Chinese burrower bugs, Schiodtella formosana, were analyzed. The results showed that the causative agents of the epizootic green muscardine dise...

journal_title：Molecular biology reports

authors： Luan F,Zhang S,Wang B,Huang B,Li Z

更新日期：2013-01-01 00:00:00

abstract：:It has been about nine decades since the proposal of Otto Warburg on the metabolism of cancer cells. Unlike normal cells which undergo glycolysis and oxidative phosphorylation in the presence of oxygen, proliferating and cancer cells exhibit an increased uptake of glucose and increased rate of glycolysis and predomina...

journal_title：Molecular biology reports

authors： Ngo H,Tortorella SM,Ververis K,Karagiannis TC

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study is to evaluate which dysregulated angiomiRs compose the specific proangiogenic microRNA signature of advanced laryngeal cancer and review the literature. Thirty-six samples from twelve patients with advanced laryngeal carcinoma were collected. Total RNA was extracted and microRNA global profiling...

journal_title：Molecular biology reports

authors： Popov TM,Giragosyan S,Petkova V,Stancheva G,Marinov T,Belitova M,Rangachev J,Popova D,Kaneva RP

更新日期：2020-07-01 00:00:00

abstract：:The phosphoenolpyruvate (PEP) carboxylase is regulated at the levels of transcription and post-translation in C4 plants in light and abundantly accumulates in leaf mesophyll cells. We report here developmental and photosynthetic regulation of stably accumulated Bacillus thuringiensis δ-endotoxin under the control of P...

journal_title：Molecular biology reports

authors： Khan MS,Ali S,Iqbal J

更新日期：2011-04-01 00:00:00

abstract：:Adriamycin is one of the most effective and useful antineoplastic agents. Acute doxorubicin cardiotoxicity involved cardiomyocyte apoptosis. In this study, we investigated whether adriamycin induced myocardium apoptosis through activation of nuclear factor kappaB in rat. Forty male Wistar rats were randomly divided in...

journal_title：Molecular biology reports

authors： Li S,E M,Yu B

更新日期：2008-12-01 00:00:00

abstract：:Alteration of the acrylamide:bisacrylamide ratio in the SDS-polyacrylamide gel used for Western blotting strongly improved the unambiguous detection of antibodies against 50-60 kDa autoantigens present in autoimmune patient sera. The relative migration of Ro52, the 56K autoantigen and calreticulin increased with reduc...

journal_title：Molecular biology reports

authors： Pruijn GJ,Bozic B,Schoute F,Rokeach LA,van Venrooij WJ

更新日期：1992-09-01 00:00:00

abstract：:Ischemic postconditioning has been described in both heart and brain. The first aim of this study was to evaluate the effects of Sevoflurane postconditioning (SP) on brain biochemical parameters, Bcl-2, Bax, c-Fos and Caspase-3 protein levels and Bcl-2, Bax, TNF-α and Caspase-3 mRNA expression in the middle cerebral a...

journal_title：Molecular biology reports

authors： Liu HG,Hua Z,Zhang Y,Wang YX,Meng C,Liang Y,Tian SY,Ma YP,Wang L,Wang WS

更新日期：2012-12-01 00:00:00

abstract：:Cold stress adversely affects the growth and development of seedling of spring soybean. Revealing responses in seedling to cold stress at proteomic level will help us to breed cold-tolerant spring soybean cultivars. In this study, to understand the responses, a proteomic analysis on the leaves of seedlings of one cold...

journal_title：Molecular biology reports

authors： Tian X,Liu Y,Huang Z,Duan H,Tong J,He X,Gu W,Ma H,Xiao L

更新日期：2015-03-01 00:00:00

abstract：:Protein phosphorylation is one of the most fundamental types of post-translational modifications and it plays a vital role in various cellular processes of eukaryotes. Among three types of phosphorylation i.e. serine, threonine and tyrosine phosphorylation, tyrosine phosphorylation is one of the most frequent and it i...

journal_title：Molecular biology reports

authors： Khan YD,Rasool N,Hussain W,Khan SA,Chou KC

更新日期：2018-12-01 00:00:00

abstract：:In our research, signal transducer and activator of transcription 5b (STAT5b) gene was studied as candidate gene associated with body weight and reproductive traits of Jinghai Yellow chicken. Single nucleotide polymorphisms (SNPs) of STAT5b gene were examined in both Jinghai Yellow chicken and three reference chicken ...

journal_title：Molecular biology reports

authors： Zhao XH,Wang JY,Zhang GX,Wei Y,Gu YP,Yu YB

更新日期：2012-04-01 00:00:00

abstract：:Nonspecific lipid transfer protein (nsLTP) is usually basic and secreted low-molecular-mass protein in plants. The 3-D structure of nsLTP1 resembles that of elicitin produced by the plant pathogen Phytophthora cryptogea, which can bind to the plant plasma membrane putative receptor and activate the downstream response...

journal_title：Molecular biology reports

authors： Wang X,Wang H,Li Y,Cao K,Ge X

更新日期：2009-04-01 00:00:00

abstract：:HIV/AIDS remains to be one of the killing diseases of mankind. Host genetic response is one of the factor which determine susceptibility to HIV and disease progression to AIDS. The aim of the present study was to evaluate the impact of ERCC2 Lyc ( 751 ) Gln (excision repair cross complementing rodent repair deficiency...

journal_title：Molecular biology reports

authors： Sobti RC,Berhane N,Mahdi SA,Kler R,Hosseini SA,Kuttiat V,Wanchu A

更新日期：2011-06-01 00:00:00

abstract：:PCR low ionic strength single-strand conformation polymorphism (PCR-LIS-SSCP) and DNA sequencing methods were used to analyze the polymorphisms within the coding region of bovine ATP1A1 gene. A novel C/A mutation was identified at the nucleotide position 2789 of the ATP1A1 mRNA, but it was silent with respect to the a...

journal_title：Molecular biology reports

authors： Liu Y,Li D,Li H,Zhou X,Wang G

更新日期：2011-01-01 00:00:00

abstract：:Knowledge in the area of genetic diversity could aid in providing useful information in the selection of material for breeding such as hybridization programs and quantitative trait loci mapping. To this end, 50 Nicotiana tabacum genotypes were genotyped with 21 primer combination of amplified fragment length polymorph...

journal_title：Molecular biology reports

authors： Dadras AR,Sabouri H,Nejad GM,Sabouri A,Shoai-Deylami M

更新日期：2014-05-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:The increasing worldwide incidence of mycobacteriosis and the need to achieve improved clinical management makes nontuberculous mycobacteria (NTM) genotyping a useful tool. However, because of technical difficulties, medium size microbiology laboratories do not attempt to compare the genetic patterns that each of thei...

journal_title：Molecular biology reports

authors： Blanco-Conde S,González-Cortés C,López-Medrano R,Palacios-Gutiérrez JJ,Diez-Tascón C,Nebreda-Mayoral T,Sierra-García MJ,Rivero-Lezcano OM

更新日期：2020-05-01 00:00:00

abstract：:Allele frequencies for the high polymorphic short tandem repeats (STR) loci PentaE, PentaD, D18S51, D21S11, TH01, D3S1358, FGA, D16S539, D7820, D13S317, vWA and D81179 were analysed in an native Amerindian population from Mato Grosso do Sul state named Terena. Deviations from Hardy-Weinberg expectations were evaluated...

journal_title：Molecular biology reports

authors： Manta FS,Silva DA,Sánchez-Diz P,Aguiar JI,Cabello PH,Carvalho EF

更新日期：2012-04-01 00:00:00

abstract：:1-aminocyclopropane-1-carboxylic acid oxidase (ACO) enzyme is a member of the Fe II-dependent family of oxidases/oxygenases which require Fe(2+) as a cofactor, ascorbate as a cosubstrate and CO(2) as an activator. This enzyme catalyses the terminal step in the plant signaling of ethylene biosynthetic pathway. A 948 bp...

journal_title：Molecular biology reports

authors： Jafari Z,Haddad R,Hosseini R,Garoosi G

更新日期：2013-02-01 00:00:00

abstract：:In attempting to produce the HAP, endoplasmic reticulum (ER) targeted apoptosis-inducing protein, as a GST-fusion protein we found that the expression of HAP, but not GST alone, induced bacterial cell death. The HAP protein inhibited the bacterial growth within 30 min after inducting HAP expression. The transmission e...

journal_title：Molecular biology reports

authors： Gan M,Qi Y,Wan Q,Kuang E,Liu Q,Liu X

更新日期：2004-09-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00