Prokaryotic expression and characterization of avian influenza A virus M2 gene as a candidate for universal recombinant vaccine against influenza A subtypes; specially H5N1 and H9N2.

abstract：:'Molecular sandwiches' composed of two aromatic amino acids separated by a hydrophilic one were found on eleven subspecies of human interferon alpha, on murine interferon alpha 2, and human interferon beta 1. In addition, another type of the sandwiches was found on several species of interferon. This confirms and exte...

journal_title：Molecular biology reports

authors： Inglot AD,Popik W,Piasecki E,Czyrski J

更新日期：1986-01-01 00:00:00

abstract：:Circulating long noncoding RNAs as biomarkers of diseases have attracted increasing attention recently. However, circulating lncRNAs in hypertension is still unexplored niche. The levels of lncRNAs GAS5, NR024118, MRAK134679, AX765700 and MRNR026574 were measured in the serum and myocardium of hypertensive rats and no...

journal_title：Molecular biology reports

authors： Wu Y,Zhang Z,Ren S,Li K,Ning Q,Jiang X

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to determine whether the Glutathione S-transferase M1 (GSTM1) and P1 (GSTP1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). Meta-analysis was performed on the associations between the GSTM1 and GSTP1 null genotypes and RA, and on the association between smoking or seroposit...

journal_title：Molecular biology reports

authors： Song GG,Bae SC,Lee YH

更新日期：2012-12-01 00:00:00

abstract：:Growth hormone-releasing hormone receptor (GHRHR) has important functions in the regulation of the growth hormone axis and the development and proliferation of pituitary somatotropes. Moreover, some mutations in mouse GHRHR can induce the dwarfism. The objective of this paper is to reveal the association of GHRHR with...

journal_title：Molecular biology reports

authors： Zhang CF,Chen H,Zhang ZY,Zhang LZ,Yang DY,Qu YJ,Hua LS,Zhang B,Hu SR

更新日期：2012-12-01 00:00:00

abstract：:The cytotoxic T lymphocyte-associated antigen 4 gene (CTLA4) has a crucial role in regulation of T cell proliferation and mediates T cell apoptosis by encoding the T cell receptor. Schizophrenia (SCZ) patients often have abnormalities in terms of the function and development of the immune system. The aim of the presen...

journal_title：Molecular biology reports

authors： Kordi-Tamandani DM,Vaziri S,Dahmardeh N,Torkamanzehi A

更新日期：2013-08-01 00:00:00

abstract：:This experiment was conducted to explore the biological functions of myogenin (MyoG) gene. MyoG gene was cloned from genome of Hu sheep by overlap extension PCR. Then, pEGFP-C1-MyoG and pcDNA3.0-MyoG fusion expression vectors was constructed and pEGFP-C1-MyoG vector had been transfected into NIH-3T3 cells by liposomes...

journal_title：Molecular biology reports

authors： Zhang Z,Xu F,Zhang Y,Li W,Yin Y,Zhu C,Du L,Elsayed AK,Li B

更新日期：2014-02-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a world-wide health problem and its incidence accounts for 1.9-3.5% of all malignant tumors. Transforming growth factor beta/Smads (TGF-beta/Smads) signaling pathway plays an important role in oncogenesis, but its function and molecular mechanisms in OSCC remain unclear. Expressi...

journal_title：Molecular biology reports

authors： Wang X,Sun W,Bai J,Ma L,Yu Y,Geng J,Qi J,Shi Z,Fu S

更新日期：2009-05-01 00:00:00

abstract：:The aim of this work was to study β-defensin 1 (SBD1) and β-defensin 2 (SBD2) genes in Valle del Belice dairy sheep in order to identify polymorphisms that can be utilized as markers of the analyzed genes, and search for the functional effects and roles of the identified polymorphisms (variation of the amino acid sequ...

journal_title：Molecular biology reports

authors： Monteleone G,Calascibetta D,Scaturro M,Galluzzo P,Palmeri M,Riggio V,Portolano B

更新日期：2011-11-01 00:00:00

abstract：:The programmed cell death (PCD) is important in maintaining the cell number homoeostasis of tissues and organs in metazoan. This process is regulated by the inhibitors of apoptosis proteins (IAPs). The function and mechanism of IAPs have been well studied in animal embryonic development and human cancers. However, the...

journal_title：Molecular biology reports

authors： He HJ,Hou L,Wang JX,Zhao XF

更新日期：2012-02-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Finger millet (Eleusine coracana L.) is an important crop used for food, forage, and industrial products. Three DNA marker techniques, random amplified polymorphic DNA (RAPD), simple sequence repeat (SSR) and cytochrome P(450) gene based markers were used for the detection of genetic polymorphism in 83 accessions of f...

journal_title：Molecular biology reports

authors： Panwar P,Saini RK,Sharma N,Yadav D,Kumar A

更新日期：2010-12-01 00:00:00

abstract：:Transcriptional factors are the major regulators of plant signaling pathways in response to environmental stresses i.e., drought, salinity and cold. Hereby, the GhMYB108-like was characterized to determine whether it regulate these stresses. The GhMYB108-like cDNA consisted of 1107 base pairs (bp) with 807 open readin...

journal_title：Molecular biology reports

authors： Ullah A,Ul Qamar MT,Nisar M,Hazrat A,Rahim G,Khan AH,Hayat K,Ahmed S,Ali W,Khan A,Yang X

更新日期：2020-03-01 00:00:00

abstract：:As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, sc...

journal_title：Molecular biology reports

authors： Chen B,Pan W,Zhang L,Liu J,Ouyang H,Nie Q,Zhang X

更新日期：2014-10-01 00:00:00

abstract：:The leaf primordium derives from the peripheral zone of shoot apical meristem. During the formation of leaf primordia, they need to establish the proximodistal, mediolateral, and ab/adaxial axes. Among these axes, the ab/adaxial axis might be the most important. ASYMMETRIC LEAVES2 (AS2) gene is a member of AS2/LATERAL...

journal_title：Molecular biology reports

authors： Sun SB,Song JP,Meng LS

更新日期：2012-04-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease in which numerous cells and mediators affect inflammatory conditions and disease severity. To compare the serum levels of adiponectin, vitamin D, copper, and zinc in patients with RA and to investigate the relationship between these parameters and RA severity...

journal_title：Molecular biology reports

authors： Khajoei S,Hassaninevisi M,Kianmehr N,Seif F,Khoshmirsafa M,Shekarabi M,Samei A,Haghighi A

更新日期：2019-04-01 00:00:00

abstract：:Dyggve melchior clausen syndrome (DMC, MIM 223800) is a very rare autosomal recessive form of skeletal dysplasia associated with various degrees of mental retardation. It is characterized by a progressive spondyloepimetaphyseal dysplasia (SEMD) with disproportionate short stature, generalized platyspondyly and lacy il...

journal_title：Molecular biology reports

authors： Abdullah,Shah PW,Nawaz S,Hussain S,Ullah A,Basit S,Ahmad W

更新日期：2020-09-01 00:00:00

abstract：:Birch (Betula platyphylla), an eminent tree species in Northeast and Inner Mongolia of China, has been widely used in architecture, furniture, and paper making in recent years. In order to retrieve genes involved in early development of B. platyphylla male inflorescence, RNA populations extracted from early and late d...

journal_title：Molecular biology reports

authors： Xing L,Liu XM

更新日期：2012-02-01 00:00:00

abstract：:The occurrence of PFD is closely related with elasticity, toughness, and functional changes of the connective tissue of the pelvic support tissue. This study aims to evaluate the effect of mechanical stretch on the differentiation of BMSCs with a co-culture with pelvic ligament fibroblasts. BMSCs was isolated and iden...

journal_title：Molecular biology reports

authors： Bing Z,Linlin L,Jianguo Y,Shenshen R,Ruifang R,Xi Z

更新日期：2012-05-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:Common bacterial blight (CBB), incited by Xanthomonas axonopodis pv. phaseoli (Xap), is a serious seed-borne disease of common bean (Phaseolus vulgaris L.) in both temperate and tropical production zones. The line HR45 is highly resistant to Xap infection on leaves and pods in both field and greenhouse. To understand ...

journal_title：Molecular biology reports

authors： Shi C,Chaudhary S,Yu K,Park SJ,Navabi A,McClean PE

更新日期：2011-01-01 00:00:00

abstract：:Changes in host immunity and parasite resistance to drugs are among the factors that contribute to decreased efficacy of antiparasitic drugs such as the antimonial compounds pentamidine, amphotericin (AMP B) and miltefosine. Bioactive natural products could be alternatives for the development of new drugs to treat neg...

journal_title：Molecular biology reports

authors： de Figueiredo Peloso E,Merli RJ,Espuri PF,Nunes JB,Colombo FA,Sierra EJT,de Paulo DC,Dos Santos MH,Carvalho DT,Marques MJ

更新日期：2020-11-01 00:00:00

abstract：:Recent reports on various cancer models demonstrate a great potential of cytosine deaminase/5-fluorocytosine suicide system in cancer therapy. However, this approach has limited success and its application to patients has not reached the desirable clinical significance. Accordingly, the improvement of this suicide sys...

journal_title：Molecular biology reports

authors： Komissarov A,Demidyuk I,Safina D,Roschina M,Shubin A,Lunina N,Karaseva M,Kostrov S

更新日期：2017-08-01 00:00:00

abstract：:NADH:ubiquinone oxidoreductase (complex I ) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone coupled to proton translocation across the membrane. The cDNA sequence of Dunaliella salina mitochondrial NADH: ubiquinone oxidoreductase 19-kD subunit contains a 682-bp ORF en...

journal_title：Molecular biology reports

authors： Liu Y,Qiao DR,Zheng HB,Dai XL,Bai LH,Zeng J,Cao Y

更新日期：2008-09-01 00:00:00

abstract：:In our research, signal transducer and activator of transcription 5b (STAT5b) gene was studied as candidate gene associated with body weight and reproductive traits of Jinghai Yellow chicken. Single nucleotide polymorphisms (SNPs) of STAT5b gene were examined in both Jinghai Yellow chicken and three reference chicken ...

journal_title：Molecular biology reports

authors： Zhao XH,Wang JY,Zhang GX,Wei Y,Gu YP,Yu YB

更新日期：2012-04-01 00:00:00

abstract：:The Fas gene polymorphisms -670A/G (rs1800682) and -1377G/A (rs2234767) have been shown to be associated with systemic lupus erythematosus (SLE), but findings are not consistent. To clarify this point, a meta-analysis was performed. We searched PubMed, CNKI, CBM and Wanfang database. Meta-odds ratios (ORs) and 95 % co...

journal_title：Molecular biology reports

authors： Xiang N,Li XM,Wang GS,Tao JH,Li XP

更新日期：2013-01-01 00:00:00

abstract：:The lily-of-the-valley Convallaria (Asparagaceae) consists of three herbaceous perennial species. The plants are commonly found in northern hemisphere, and are best-known for their ornamental and pharmaceutical value. In order to assess the genetic structure, diversity and demographic history of Convallaria species, 1...

journal_title：Molecular biology reports

authors： Lu QX,Gao J,Wu JJ,Zhou X,Wu X,Li MD,Wei YK,Wang RH,Qi ZC,Li P

更新日期：2020-04-01 00:00:00

abstract：:Stats are latent transcription factors involved in normal cellular signaling in response to cytokine or growth factor stimulation. Constitutive activation of Stats (primarily Stat3 and Stat5) has been implicated in growth dysregulation and oncogenesis. Furthermore, increased activation of Stats has been observed in se...

journal_title：Molecular biology reports

authors： Barboza JA,Wang S,Schaefer TS

更新日期：2004-03-01 00:00:00

abstract：:Transcriptome from high throughput sequencing-by-synthesis is a good resource of molecular markers. In this study, we present utility of massively parallel sequencing by synthesis for profiling the transcriptome of red pepper (Capsicum annuum L. TF68) using 454 GS-FLX pyrosequencing. Through the generation of approxim...

journal_title：Molecular biology reports

authors： Lu FH,Cho MC,Park YJ

更新日期：2012-03-01 00:00:00

abstract：:The present study brings out the preventive role of (-)-epigallocatechin-gallate (EGCG) on cardiac mitochondrial metabolism and apoptosis in cigarette smoke (CS)-exposed rats. The CS-exposed rats showed significantly decreased activities of TCA cycle enzymes and mitochondrial enzymatic antioxidants, on the other hand,...

journal_title：Molecular biology reports

authors： Adikesavan G,Vinayagam MM,Abdulrahman LA,Chinnasamy T

更新日期：2013-12-01 00:00:00

abstract：:Here, we document changes in cell motility and organization of the contractile apparatus of human umbilical cord Wharton's jelly mesenchymal stem cells (MSCWJ-1) in the process of replicative senescence. Colocalization dynamics of F-actin and actin-binding proteins (myosin-9, α-actinin-4, RhoA) were examined in the MS...

journal_title：Molecular biology reports

authors： Bobkov D,Polyanskaya A,Musorina A,Lomert E,Shabelnikov S,Poljanskaya G

更新日期：2020-05-01 00:00:00