Expression of TopBP1 in hereditary breast cancer.

abstract：:This study is aimed to identify polymorphic microsatellite markers and establish their potential for population genetics studies in three carp (family cyprinidae; subfamily cyprininae) species, Labeo rohita, Catla catla and Cirrhinus mrigala through use of cyprinid primers. These species have high commercial value and...

journal_title：Molecular biology reports

authors： Masih P,Luhariya RK,Das R,Gupta A,Mohindra V,Singh RK,Srivastava R,Chauhan UK,Jena JK,Lal KK

更新日期：2014-08-01 00:00:00

abstract：:J The [Ca2+] regulation of contractile ATPase flux, Jp, in skeletal muscle was analysed by computation of the Response R(Jp) Ca2+ for a 10 Hz range of electrical stimulation frequencies. Results of our analysis of the kinetic controls in ATP free energy metabolism in a network model of contracting muscle (J.A.L. Jenes...

journal_title：Molecular biology reports

authors： Jeneson JA

更新日期：2002-01-01 00:00:00

abstract：:CyclinD1 over-expression is the key pathogenetic event underlying airway smooth muscle (ASM) proliferation. Human antigen R (HuR) is a ubiquitously expressed RNA-binding protein, and is known to regulate the expression of multiple cell cycle regulators. The aim of the study is to investigate whether HuR might also be ...

journal_title：Molecular biology reports

authors： Zhang P,Cao M,Liu Y,Lv Z,Yang Q,Lin X,Li H,Wan Q

更新日期：2012-05-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:Using kinetics of approach to steady state labeling, we have found that liver poly(A)+ mRNAs fall into three populations, differing in stability and probably in processing, as reflected in their dissimilar delays in reaching polyribosomes and turnover times. There are mRNA-1 (delay 10 min, half-life 1 hr); mRNA-2(dela...

journal_title：Molecular biology reports

authors： Lubimova EV,Chernovskaja TV,Lerman MI

更新日期：1975-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERP...

journal_title：Molecular biology reports

authors： An L,Yang T,Zhang Y,Lin Y,Zhang H,Jiao X,Hua L,Dai H,Wang C

更新日期：2012-02-01 00:00:00

abstract：:Complementary DNA to mouse globin mRNA was prepared using viral reverse transcriptase. Molecular hybridisation of this cDNA to Friend virus RNA demonstrates the absence of globin gene sequences. ...

journal_title：Molecular biology reports

authors： Pragnell IB,Gilmour RS

更新日期：1973-12-01 00:00:00

abstract：:Adequate metabolic adaptation of key tissues playing an essential role for bioenergetic homeostasis and lactogenesis is critical in cows to adapt to changes in energy requirements and physiological processes during the lactation period. Mitochondria are recognized as central to meet energy needs and maintaining of met...

journal_title：Molecular biology reports

authors： Weikard R,Kuehn C

更新日期：2018-10-01 00:00:00

abstract：:Zbtb7a is a transcription factor whose dysfunction is correlated to the development of several types of cancer, including hepatocellular carcinoma (HCC). It generally acts as a repressor of transcription downregulating the expression of several target genes including oncosuppressors ARF and Rb. In this study, Zbtb7a w...

journal_title：Molecular biology reports

authors： Di Palo A,Siniscalchi C,Mosca N,Russo A,Potenza N

更新日期：2020-06-01 00:00:00

abstract：:Epidemiological studies found inconsistent results on the association of two variants on TGFBR1 (TGFBR1*6A and Int7G24A) with colorectal cancer (CRC) risk. The present study was aimed to evaluate the association of these two variants with CRC susceptibility via the meta-analysis methods. For variant TGFBR1*6A, nine re...

journal_title：Molecular biology reports

authors： Zhang X,Wu L,Sheng Y,Zhou W,Huang Z,Qu J,Gao G,Cai D,Zhang M

更新日期：2012-03-01 00:00:00

abstract：:Etiological factors for coronary artery disease (CAD) involve a wide range of gene and environmental interactions. One of the systems being implicated in the pathophysiology of CAD is the renin-angiotensin system (RAS). However, the genetic polymorphisms of this system have not been widely studied in Iranian patients ...

journal_title：Molecular biology reports

authors： Firouzabadi N,Tajik N,Bahramali E,Bakhshandeh H,Maadani M,Shafiei M

更新日期：2013-08-01 00:00:00

abstract：:The objective of this study was to analyze possible associations between single nucleotide polymorphisms (SNPs) in the Myf5 gene with chicken growth and reproductive traits. SNPs in Myf5 of the Jinghai yellow chicken were detected by the polymerase chain reaction single-strand conformation polymorphism method and the ...

journal_title：Molecular biology reports

authors： Tang Y,Zhang T,Zhang G,Wang J,Fan Q,Chen X,Wei Y,Han K,Wang Y

更新日期：2014-10-01 00:00:00

abstract：:In vivo and in vitro expressed N-terminal sequence of EWS (EAD) and hsRPB7 (subunit of human RNA polymerase II) were probed for protein-protein interactions using pull-down assays. In result, it was found that the proteins 57Z (residues 1-57 of EAD) and hsRPB7 interact in vitro forming a stable complex. The direct int...

journal_title：Molecular biology reports

authors： Todorova R

更新日期：2009-07-01 00:00:00

abstract：:Wnts are secreted lipid-modified signaling proteins. Activation of Wnt signalling in many tissues has also been associated with cancer. In many eukaryotes, expression of nuclear-encoded mRNA can be strongly inhibited by the presence of a small double-stranded RNA corresponding to exon sequences in the mRNA. In this st...

journal_title：Molecular biology reports

authors： Xiang Y,Lin G,Zhang Q,Tan Y,Lu G

更新日期：2008-06-01 00:00:00

abstract：:BURP domain-containing genes comprise a large plant-specific family, yet the functions are very poorly understood, especially in maize (Zea mays) and sorghum (Sorghum vulgare). In this study, 26 BURP family genes in maize (ZmBURP01-15) and sorghum (SbBURP01-11) were identified including the gene structure, phylogeneti...

journal_title：Molecular biology reports

authors： Gan D,Jiang H,Zhang J,Zhao Y,Zhu S,Cheng B

更新日期：2011-10-01 00:00:00

abstract：:The aim of this study was to develop microsatellite markers as a tool to study population structure, genetic diversity and effective population size of Echinopsis chiloensis, an endemic cactus from arid and semiarid regions of Central Chile. We developed 12 polymorphic microsatellite markers for E. chiloensis using ne...

journal_title：Molecular biology reports

authors： Ossa CG,Larridon I,Peralta G,Asselman P,Pérez F

更新日期：2016-12-01 00:00:00

abstract：:Mollusks lack an adaptive immune system and rely solely on the innate immune response. The nuclear factor-kappa B (NF-κB) signaling pathway is one of the most important components of the innate immune system and its activity is regulated by physical interaction with the inhibitor of NF-κB (IκB) protein. The manila cla...

journal_title：Molecular biology reports

authors： Lee Y,Wickamarachchi WD,Whang I,Oh M,Umasuthan N,De Zoysa M,Oh C,Kang DH,Lee J

更新日期：2013-02-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:Bone abnormalities as a consequence of osteoblast deregulation are associated with several diseases such as diabetes and chronic kidney disease. Important role for oxidized low density lipoproteins (oxLDL) in the pathophysiology of bone disorders has been reported. However, little is known about the effects and mechan...

journal_title：Molecular biology reports

authors： Dawodu D,Patecki M,Dumler I,Haller H,Kiyan Y

更新日期：2019-06-01 00:00:00

abstract：:Emergence of MDR 'superbugs' inflamed a severe sense of urgency amongst scientists aiming at the discovery of novel potential drug molecules. Bacteria of the genus Streptomyces are really worth investigating for their immense potential to produce natural compounds of pharmaceutical importance. In the present study, th...

journal_title：Molecular biology reports

authors： Kumar P,Chauhan A,Kumar M,Kuanr BK,Solanki R,Kapur MK

更新日期：2020-09-01 00:00:00

abstract：:The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...

journal_title：Molecular biology reports

authors： Mastrangelo S,Sardina MT,Riggio V,Portolano B

更新日期：2012-01-01 00:00:00

abstract：:Consistent with its precloning characterization from the cellulolytic Bacillus sp., beta-1,4-endoglucanase purified from the recombinant E. coli exhibited maximum activity at 60 degrees C and pH 7.0. It was highly specific for CMC hydrolysis, with stability up to 70 degrees C and over a pH range of 6.0-8.0. The K(m) a...

journal_title：Molecular biology reports

authors： Afzal S,Saleem M,Yasmin R,Naz M,Imran M

更新日期：2010-04-01 00:00:00

abstract：:The current study represents the first molecular characterization of freshwater fish species in Egypt from two major fish resources; the River Nile and Lake Nasser. A total of 160 DNA barcodes using a 655-bp-long fragment of the mitochondrial cytochrome oxidase subunit I (COI) gene were generated from 37 species belon...

journal_title：Molecular biology reports

authors： Ali FS,Ismail M,Aly W

更新日期：2020-08-01 00:00:00

abstract：:As an essential signaling modulator, Src gene appears to be necessary for increased expression of the prolactin receptor, normal downstream signaling, and alveolar cell organization. In this study, we detected the polymorphism of Src gene by polymerase chain reaction-restriction fragment length polymorphism assay (PCR...

journal_title：Molecular biology reports

authors： Liu W,Wang J,Li Q,Ju Z,Huang J,Wang H,Liu S,Li J,Zhong J,Wang C

更新日期：2010-12-01 00:00:00

abstract：:The circular dichroism spectra of poly(dG). poly(dC) have been studied as a function of pH in 0.15 M NaCl solution. Acid titration to pH 2.5 showed two transitions, one around pH 5, the second below pH 3. These transitions are disproportionation reactions and are not due to the dissociation of the complexes. Alkaline ...

journal_title：Molecular biology reports

authors： Thiele D,Sarocchi MT,Guschlbauer W,Marck C

更新日期：1973-10-01 00:00:00

abstract：:Brucella cell surface protein (BCSP31) is potentially useful for diagnosing brucellosis. We aimed to establish a monoclonal antibody (MAb) against Brucella melitensis BCSP31 and to investigate its distribution in diagnosis. Soluble recombinant BCSP31 was successfully expressed and purified. Two MAbs (1F1 and 1E5) agai...

journal_title：Molecular biology reports

authors： Zhang L,Wu XA,Zhang FL,An CH,Sun YX,Bai WT,Xu ZK

更新日期：2012-01-01 00:00:00

abstract：:The influence of peptidyl-tRNA on the dissociation of yeast 80 S ribosomes into subunits was studied. For this purpose temperature-sensitive (ts) suppressor strain of yeast Saccharomyces cervisiae carrying a defect in peptide chain termination was used. It was found that peptidyl-tRNA did not influence the dissociatio...

journal_title：Molecular biology reports

authors： Surguchov AP,Fominykch ES,Lyzlova LV

更新日期：1978-06-16 00:00:00

abstract：:The stem cells in freshwater flatworms (planarian) are called neoblasts. Neoblasts are capable of proliferation and differentiation into every cell type, including the gametes. For the investigation of the mechanisms of stem cells proliferation and differentiation the proper evaluation of changes in the cell cycle of ...

journal_title：Molecular biology reports

authors： Ermakov AM,Ermakova ON,Kudravtsev AA,Kreshchenko ND

更新日期：2012-03-01 00:00:00

abstract：:An ORF having a potential to code for a polypeptide of 79 amino acids has been identified within 993 nt sequence of 2 kb EcoRI-W fragment of Spodoptera litura nucleopolyhedrovirus (SpltNPV-I). Nucleotide and deduced amino acid sequence analyses showed its identity with the ubiquitin homologue of eukaryotes (79-80%), M...

journal_title：Molecular biology reports

authors： Jain M,Das RH

更新日期：2004-12-01 00:00:00