The effect of chemical carcinogenesis on rat glutathione S-transferase P1 gene transcriptional regulation.

abstract：:Several studies have examined the effects of the tumor necrosis factor-α (TNF-α) -308 A/G and lymphotoxin-α (LT-α) +252 A/G polymorphisms on susceptibility to sarcoidosis, showing mixed results. The purpose of this study was to examine whether the TNF-α -308 A/G and LT-α +252 A/G polymorphisms confer susceptibility to...

journal_title：Molecular biology reports

authors： Song GG,Kim JH,Lee YH

更新日期：2014-01-01 00:00:00

abstract：:The phosphoenolpyruvate (PEP) carboxylase is regulated at the levels of transcription and post-translation in C4 plants in light and abundantly accumulates in leaf mesophyll cells. We report here developmental and photosynthetic regulation of stably accumulated Bacillus thuringiensis δ-endotoxin under the control of P...

journal_title：Molecular biology reports

authors： Khan MS,Ali S,Iqbal J

更新日期：2011-04-01 00:00:00

abstract：:The cbb (3)-type oxidases are members of the heme-copper oxidase superfamily, distant by sequence comparisons, but sharing common functional characteristics. The cbb (3) oxidases are missing an active-site tyrosine residue that is absolutely conserved in all A and B-type heme-copper oxidases. This tyrosine is known to...

journal_title：Molecular biology reports

authors： Oztürk M,Watmough NJ

更新日期：2011-06-01 00:00:00

abstract：:The aim of this study was to explore the association between alpha-thalassemia, fetal hemoglobin, hematological indices, and clinical adverse events in Angolan sickle cell disease pediatric patients. A total of 200 sickle cell disease (SCD) children were sampled in Luanda and Caxito. A venous blood sample was collecte...

journal_title：Molecular biology reports

authors： Santos B,Delgadinho M,Ferreira J,Germano I,Miranda A,Arez AP,Faustino P,Brito M

更新日期：2020-07-01 00:00:00

abstract：:In clinical practice, most patients with non small cell lung cancer (NSCLC) who respond to tyrosine kinase inhibitors eventually progress because of an acquired resistance mutation, T790M, in epidermal growth factor receptor (EGFR). Thus, it is important to identify a new drug to reduce resistance. The aim of this stu...

journal_title：Molecular biology reports

authors： Zhu H,Cheng H,Ren Y,Liu ZG,Zhang YF,De Luo B

更新日期：2012-04-01 00:00:00

abstract：:Fascin homologue 1 (FSCN1) has established roles in cell adhesion, motility, and cell-cell interactions. Our LongSAGE analysis suggested that FSCN1 was potentially differentially expressed in prenatal pig skeletal muscle. We have cloned the genomic DNA and mRNA sequence of FSCN1 gene and mapped it to SSC3p16-p17. The ...

journal_title：Molecular biology reports

authors： Tang ZhL,Zhang XJ,Yang ShL,Mu YL,Cui WT,Ao H,Li K

更新日期：2010-06-01 00:00:00

abstract：:Graft versus host disease (GVHD) is a major complication of bone marrow transplantation (BMT). Numerous studies have shown the potential role of cytokine genotypes in the occurrence of GVHD. In this retrospective, case-control study we aimed to investigate the association between 13 cytokine genes and acute GVHD (aGVH...

journal_title：Molecular biology reports

authors： Noori-Daloii MR,Jalilian N,Izadi P,Sobhani M,Rabii-Gilani Z,Yekaninejad MS

更新日期：2013-08-01 00:00:00

abstract：:The sterol regulatory element binding factor 1 (SREBP1) gene plays an important role in the biosynthesis of fatty acids. The aim of this study was to investigate the association between SNPs within SREBP1 gene and fatty acid composition of muscle fat and marbling score in a commercial population of Korean cattle. Amon...

journal_title：Molecular biology reports

authors： Lee Y,Oh D,Lee J,La B,Yeo J

更新日期：2013-01-01 00:00:00

abstract：:The spleen plays a crucial role in innate and adaptive immunity in bony fish. Consequently, this organ is well suited to assess the immune competence of an organism and hence provides useful information for comparison and classification of production traits of food fish, such as robustness and susceptibility. To gain ...

journal_title：Molecular biology reports

authors： Köbis JM,Rebl A,Kühn C,Goldammer T

更新日期：2013-02-01 00:00:00

abstract：:Spata34 is a testis-specific-expressed gene which exerts diverse functions in testis development. This study intends to examine the expression profiles of Spata34 in postnatal rat testis, and explore its potential roles in cell proliferation in vitro. We found that the mRNA and protein expression levels of Spata34 wer...

journal_title：Molecular biology reports

authors： Nie D,Li H,Liu Y,Liao Z

更新日期：2018-12-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:The objective of this study was to analyze possible associations between single nucleotide polymorphisms (SNPs) in the Myf5 gene with chicken growth and reproductive traits. SNPs in Myf5 of the Jinghai yellow chicken were detected by the polymerase chain reaction single-strand conformation polymorphism method and the ...

journal_title：Molecular biology reports

authors： Tang Y,Zhang T,Zhang G,Wang J,Fan Q,Chen X,Wei Y,Han K,Wang Y

更新日期：2014-10-01 00:00:00

abstract：:Yellow lupin seeds (Lupinus luteus) cytoplasmic tRNAGlu was isolated and the primary structure was determined to be: (sequence in text) AGU CCCGGCGACGGAACCAOH. It is 76 nucleotides long and contains 8 modified nucleosides: 2 residues of pseudouridine, ribothymidine, 3 dihydrouridines, 5-methylcytosine and 1-methyladen...

journal_title：Molecular biology reports

authors： Barciszewska M,Barciszewski J

更新日期：1988-01-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:Since Mexican mestizos are an admixed population, it is necessary to determine the effects that the substructure of the population has on genetic and forensic parameters. With this aim, a study was performed with 15 STR loci (CODIS plus D2S1338 and D19S433) on 1,640 unrelated Mexican mestizos. We determine allele and ...

journal_title：Molecular biology reports

authors： Noris G,Santana C,Meraz-Ríos MA,de Lourdes Munoz M,Majluf-Cruz A,Magaña JJ,Granados J,Quezada R,Revilla MC,Martínez-Salas S,Xihuitl S,Martínez de la Escalera G,Díaz-Badillo A,Calderon-Aranda ES,Gómez R

更新日期：2012-12-01 00:00:00

abstract：:Iron may be implicated in the generation of oxidative stress by the catalyzing the Haber-Weiss or Fenton reaction. On the other hand, oxidative stress has been implicated in the pathogenesis of age-related macular degeneration (AMD) and heme oxygenase-1 (HO-1), encoded by the HMOX1 gene and heme oxygenase-2 (HO-2), en...

journal_title：Molecular biology reports

authors： Synowiec E,Szaflik J,Chmielewska M,Wozniak K,Sklodowska A,Waszczyk M,Dorecka M,Blasiak J,Szaflik JP

更新日期：2012-03-01 00:00:00

abstract：:Tall fescue is a perennial cool-season grass with economic importance especially in temperate regions of the northern hemisphere. This study was done to assess the genetic diversity and population structure of 90 tall fescue populations and cultivars using ISSR and EST-SSR markers in order to categorize valuable popul...

journal_title：Molecular biology reports

authors： Shahabzadeh Z,Mohammadi R,Darvishzadeh R,Jaffari M

更新日期：2020-01-01 00:00:00

abstract：:Lac insects are commercial scale insects with high economic value. The combined molecular phylogeny of 20 lac insect populations was generated using elongation factor 1 alpha, mitochondrial cytochrome c oxidase subunit I and the small subunit ribosomal RNA gene loci. The 20 populations of lac insects clustered into fo...

journal_title：Molecular biology reports

authors： Chen H,Chen X,Feng Y,Yang H,He R,Zhang W,Yang Z

更新日期：2013-10-01 00:00:00

abstract：:Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...

journal_title：Molecular biology reports

authors： Mancilla IA,Coatti GC,Biazi BI,Zanetti TA,Baranoski A,Marques LA,Corveloni AC,Lepri SR,Mantovani MS

更新日期：2019-12-01 00:00:00

abstract：:In the present work, Site-directed mutagenesis to insert the Glu50Lys amino acid substitution was achieved by PCR using plasmid pBluescript-OPTN. Mutated human OPTN(E50K) gene-driven mouse c-kit promoter was constructed and confirmed by endonuclease digestion and sequence analysis. Transgenic mice were generated via t...

journal_title：Molecular biology reports

authors： Meng Q,Xiao Z,Yuan H,Xue F,Zhu Y,Zhou X,Yang B,Sun J,Meng B,Sun X,Cheng F

更新日期：2012-02-01 00:00:00

abstract：:β-Catenin plays a crucial role in embryonic development and responds to the activation of several signal transduction pathways. In this paper, in order to understand the functions of β-catenin gene in early embryonic development of Artemia sinica, the complete cDNA sequence was cloned for the first time using RACE tec...

journal_title：Molecular biology reports

authors： Li X,Hou L,Ma J,Liu Y,Zheng L,Zou X

更新日期：2012-01-01 00:00:00

abstract：:This study was designed to identify the differential expression of the canonical transient receptor potential (TRPC) channels in the left ventricle of spontaneously hypertensive rats (SHR). Echocardiography studies were performed to compare the left ventricular function in SHR vs. Wistar-Kyoto rats (WKY), and the mRNA...

journal_title：Molecular biology reports

authors： Liu FF,Ma ZY,Li DL,Feng JB,Zhang K,Wang R,Zhang W,Li L,Zhang Y

更新日期：2010-07-01 00:00:00

abstract：:Combined treatment with niacin and chromium has been found to have a protective effect against oxidative damage to different tissues of hyperlipidemic rats. But its effects on vascular endothelial dysfunction are less clear. This study was performed to investigate the effect of combined treatment with niacin and chrom...

journal_title：Molecular biology reports

authors： Niu N,Yu YH,Wang Y,Wang LJ,Li Q,Guo LM

更新日期：2009-07-01 00:00:00

abstract：:Autoantibodies to SS-A/Ro are among the most common found in sera of patients with systemic rheumatic diseases. These autoimmune diseases can affect various organ systems of the body and are variable in their manifestations and presentation. One of the autoimmune targets is the 60 kDa SS-A/Ro protein known to be assoc...

journal_title：Molecular biology reports

authors： Wang D,Buyon JP,Chan EK

更新日期：1996-01-01 00:00:00

abstract：:Substantial evidence has demonstrated that platelet-derived growth factor-D (PDGF-D) is tightly associated with the development and progression of tumors. However, its biological functions in esophageal squamous cell carcinoma (ESCC) remain to be delineated. In this study, we found that expressions of PDGF-D mRNA and ...

journal_title：Molecular biology reports

authors： Han Y,Guo XH,Zheng QF,Zhu YL,Fan YY,Zhang XY

更新日期：2013-03-01 00:00:00

abstract：:Several lines of evidence indicate that inflammatory processes play pivotal role in the development of intracranial aneurysm (IA). Recently, polymorphisms in the interleukin-12 (IL-12) gene were shown to be associated with immune-mediated inflammatory disease. The aim of this study was to investigate the interactions ...

journal_title：Molecular biology reports

authors： Li LJ,Pan XM,Sima X,Li ZH,Zhang LS,Sun H,Zhu Y,Liang WB,Gao LB,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:Recent evidence supports a role of Toll-like receptor (TLR) signaling in the development of atherosclerotic lesions. It was confirmed that the presence of functional TLR4 promotes a proinflammatory phenotype and proliferation of vascular smooth muscle cells (VSMCs). Here we tested whether designed TLR4 small interferi...

journal_title：Molecular biology reports

authors： Li H,Xu H,Liu S

更新日期：2011-02-01 00:00:00

abstract：:Bacterial leaf streak (BLS) caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an important disease of rice, which is responsible for the economic losses worldwide. Functional investigation of differentially expressed protein genes (DEPGs) from rice (Oryza sativa L.) upon Xoc infection provides insight into the molec...

journal_title：Molecular biology reports

authors： Guo L,Guo C,Li M,Wang W,Luo C,Zhang Y,Chen L

更新日期：2014-01-01 00:00:00

abstract：:Molecular abnormalities in the 11p15.5 imprinted gene cluster lead to two different growth diseases: Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS). They are mainly caused by epigenetic alterations in one of the two imprinting 11p15 control regions (ICR1 and ICR2). These CpG-rich regions are diffe...

journal_title：Molecular biology reports

authors： Lukova M,Todorova A,Todorov T,Mitev V

更新日期：2013-01-01 00:00:00

abstract：:The study was done to identify the candidate causal single nucleotide polymorphisms (SNPs) and candidate causal mechanisms that contribute to Parkinson's disease (PD) susceptibility and to generate a SNP to ene to pathway hypothesis using an analytical pathway-based approach. We used a PD genome-wide association study...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-03-01 00:00:00