Identification of differentially expressed genes under heat stress conditions in rice (Oryza sativa L.).

abstract：:Spata34 is a testis-specific-expressed gene which exerts diverse functions in testis development. This study intends to examine the expression profiles of Spata34 in postnatal rat testis, and explore its potential roles in cell proliferation in vitro. We found that the mRNA and protein expression levels of Spata34 wer...

journal_title：Molecular biology reports

authors： Nie D,Li H,Liu Y,Liao Z

更新日期：2018-12-01 00:00:00

abstract：:The purpose of this study is to investigate the effect of H2O2 on the aging of melanogenesis in human melanocytes. The staining of SA-β-galactosidase, an aging marker, was remarkably increased in the cells aged with H2O2 at 62.5 µM or more compared with young cells. The intracellular H2O2 level and melanin synthesis w...

journal_title：Molecular biology reports

authors： Ko H,Kim MM

更新日期：2019-04-01 00:00:00

abstract：:Patients with β-thalassemia suffer from a lack or absence of the beta-globin chain of normal hemoglobin (Hb). Therefore, an increase in fetal Hb (HbF) levels could improve the clinical status of these patients. Downregulation of BCL11A, a key regulatory transcription factor, could ameliorate the clinical status of tha...

journal_title：Molecular biology reports

authors： Gholampour MA,Asadi M,Naderi M,Azarkeivan A,Soleimani M,Atashi A

更新日期：2020-05-01 00:00:00

abstract：:As-ClC (chloride channels protein from Artemia sinica), a member from the chloride channels protein family, is a α-helical membrane protein predicted to traverse the cell membrane 11 times. It is important for several physiological functions such as cell volume regulation, cell proliferation, growth and differentiatio...

journal_title：Molecular biology reports

authors： Zhang Q,Hou M,Li Q,Han L,Yuan Z,Tan J,Du B,Zou X,Hou L

更新日期：2013-05-01 00:00:00

abstract：:Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an ex...

journal_title：Molecular biology reports

authors： Gismondi A,Nanni V,Monteleone V,Colao C,Di Marco G,Canini A

更新日期：2021-01-01 00:00:00

abstract：:A reduction in the number of functional β-cells is the central pathological event in diabetes. Liver and ventral pancreas differentiates simultaneously in the same general domain of cells within embryonic endoderm. In addition, the precursor cell population being bi-potential may be targeted for either pancreas or liv...

journal_title：Molecular biology reports

authors： Sarkar S,Munshi C,Chatterjee S,Mukherjee S,Bhattacharya S

更新日期：2019-10-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality, influenced by both environmental factor and genetic factor. ADAM33 gene was found to be associated with asthma, declined lung function and COPD. The purpose of the study was to test whether S...

journal_title：Molecular biology reports

authors： Xiao J,Han J,Wang X,Hua D,Su D,Bao Y,Lv F

更新日期：2011-11-01 00:00:00

abstract：:The suppressors of cytokine signaling (SOCS) proteins are originally identified as negative regulators of cytokine-activated Janus kinase/signal transducers and activators of transcription signaling pathway, but increasing evidence reveals that SOCS proteins play an important role in the development of type 2 diabetes...

journal_title：Molecular biology reports

authors： Feng X,Tang H,Leng J,Jiang Q

更新日期：2014-01-01 00:00:00

abstract：:The water-soluble group B3 vitamin nicotinamide (NAM) is involved in a wide range of physical processes through biosynthetically converted to nicotinamide adenine dinucleotide (NAD(+)). In addition to its pivotal role in energy metabolism, NAD(+) is also the indispensable substrate of poly (ADP-ribose) polymerase-1 (P...

journal_title：Molecular biology reports

authors： Zhang XM,Jing YP,Jia MY,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:The influence of peptidyl-tRNA on the dissociation of yeast 80 S ribosomes into subunits was studied. For this purpose temperature-sensitive (ts) suppressor strain of yeast Saccharomyces cervisiae carrying a defect in peptide chain termination was used. It was found that peptidyl-tRNA did not influence the dissociatio...

journal_title：Molecular biology reports

authors： Surguchov AP,Fominykch ES,Lyzlova LV

更新日期：1978-06-16 00:00:00

abstract：:The GRAS gene family is a family of transcription factors that regulates plant growth and development. Despite being well-studied in many plant species, little is known about this gene family in orchardgrass (Dactylis glomerata L.), one of the top four economically important perennial forage grasses cultivated worldwi...

journal_title：Molecular biology reports

authors： Xu X,Feng G,Huang L,Yang Z,Liu Q,Shuai Y,Zhang X

更新日期：2020-03-01 00:00:00

abstract：:JAK/STAT signaling pathway is involved in many diseases, including autoimmune diseases, which are characterized by a close interconnection between immune and bone system. JAK/STAT pathway is involved in bone homeostasis and plays an important role in proliferation and differentiation of some cell types, including oste...

journal_title：Molecular biology reports

authors： Sanpaolo ER,Rotondo C,Cici D,Corrado A,Cantatore FP

更新日期：2020-11-01 00:00:00

abstract：:In clinic, the patients with acute myocardial infarction (AMI) are at high risk to develop ischemia-induced ventricular arrhythmias leading to sudden cardiac death (SCD). Some studies suggest that individual susceptibility to ischemia-induced arrhythmia may be related to the genes encoding ion channels. One of them is...

journal_title：Molecular biology reports

authors： Wan J,Xiong C,Zheng F,Zhou X,Huang C,Jiang H

更新日期：2008-06-01 00:00:00

abstract：:Cartilage has a limited self-repair capability and the repair of large cartilage defects remains a challenge in clinic. This study aimed to investigate the effect of mesenchymal stem cells (MSCs) loaded three-dimensional bilayer collagen scaffold for cartilage repair. Cross-linked three-dimensional bilayer collagen sc...

journal_title：Molecular biology reports

authors： Qi Y,Zhao T,Xu K,Dai T,Yan W

更新日期：2012-02-01 00:00:00

abstract：:Many studies have examined the association between the GSTP1 Ile105Val (rs 1695) gene polymorphism and lung cancer risk in various populations, but their results have been inconsistent. To assess this relationship more precisely, a meta-analysis was performed. The PubMed and CNKI database was searched for case-control...

journal_title：Molecular biology reports

authors： Xu CH,Wang Q,Zhan P,Qian Q,Yu LK

更新日期：2014-07-01 00:00:00

abstract：:A full-length cDNA encoding wheat peroxisomal ascorbate peroxidase (pAPX) was cloned by Suppression Subtractive Hybridization (SSH) and in silico approach. The cDNA was 1027 bp in length and contained a complete ORF of 876 bp, which encodes a protein of 292 amino acid residues. Its deduced amino acids sequence had 84%...

journal_title：Molecular biology reports

authors： Chen Y,Wang H,Wang X,Cao A,Chen P

更新日期：2006-09-01 00:00:00

abstract：:Seed development is a complex process controlled by temporal and spatial expression of many transcription factors (TF) inside the developing seed. In the present study, transcript profiles of all the 30 members of rice DofTFs from flowering to seed development stages were analyzed. It was found that 16 Dof genes besid...

journal_title：Molecular biology reports

authors： Gaur VS,Singh US,Kumar A

更新日期：2011-04-01 00:00:00

abstract：:Small ubiquitin-like modifier (SUMO) participates in post-translational modification of various target proteins. SUMOylation is an important molecular regulatory mechanism for plants to respond to abiotic stress. In the present study, GmSUMO2 gene was isolated from soybean seedlings for further study because of the hi...

journal_title：Molecular biology reports

authors： Guo J,Wang S,Wang G,Lu R,Wang Y,Guo Y,Ji W

更新日期：2020-05-01 00:00:00

abstract：:In order to extend the knowledge of rabies pathogenesis, a two-dimensional electrophoresis/mass spectrometry based postmortem comparative proteomics analysis was carried out on human brain samples. Alteration in expression profile of several proteins was detected. Proteins related to cytoskeleton, metabolism, proteaso...

journal_title：Molecular biology reports

authors： Farahtaj F,Zandi F,Khalaj V,Biglari P,Fayaz A,Vaziri B

更新日期：2013-11-01 00:00:00

abstract：:Polyomavirus JC (JCPyV) is a ubiquitous human neurotropic virus that can cause progressive multifocal leukoencephalopathy (PML), sometimes as a consequence of drug treatment for disabling diseases, including Multiple Sclerosis. JCPyV expresses microRNAs (miRNAs), and in particular miR-J1-5p, but at now we have limited...

journal_title：Molecular biology reports

authors： Agostini S,Mancuso R,Costa AS,Guerini FR,Clerici M

更新日期：2020-11-01 00:00:00

abstract：:Beta(2)-microglobulin (beta(2)m), a protein necessary for proper folding, peptide binding, and surface display of class I antigens plays an important role in immune response. The full-length cDNA containing beta(2)m was cloned from the spleen cDNA library of large yellow croaker Pseudosciaena crocea (Pscr-beta ( 2 ) m...

journal_title：Molecular biology reports

authors： Yu S,Chen X,Ao J

更新日期：2009-09-01 00:00:00

abstract：:Proteasomes (prosomes) are large multiprotein complexes. They are involved in protein degradation of ubiquitin-conjugated proteins and in the generation of MHC class I peptides. We gave further evidence that they interfere with in vitro protein synthesis. Proteasomes inhibit the translation of Tobacco mosaic virus RNA...

journal_title：Molecular biology reports

authors： Homma S,Horsch A,Pouch MN,Petit F,Briand Y,Schmid HP

更新日期：1994-01-01 00:00:00

abstract：:Silky Fowl is a natural mutant with hyperpigmentation of various internal tissues. Although the mechanism of hyperpigmentation remains unclear, recent studies have shown that the abnormal migration of melanoblast and the absence of environmental barrier molecules are responsible for the hyperpigmentation in Silky Fowl...

journal_title：Molecular biology reports

authors： Li Y,Zhu X,Yang L,Li J,Lian Z,Li N,Deng X

更新日期：2011-02-01 00:00:00

abstract：:Vitiligo is a common chronic depigmented skin disease characterized by melanocyte loss or dysfunction in the lesion. The pathogenesis of vitiligo has not been fully clarified. Most studies have suggested that the occurrence and progression of vitiligo are due to multiple factors and gene interactions in which noncodin...

journal_title：Molecular biology reports

authors： Yan S,Shi J,Sun D,Lyu L

更新日期：2020-04-01 00:00:00

abstract：:This experiment was conducted to explore the biological functions of myogenin (MyoG) gene. MyoG gene was cloned from genome of Hu sheep by overlap extension PCR. Then, pEGFP-C1-MyoG and pcDNA3.0-MyoG fusion expression vectors was constructed and pEGFP-C1-MyoG vector had been transfected into NIH-3T3 cells by liposomes...

journal_title：Molecular biology reports

authors： Zhang Z,Xu F,Zhang Y,Li W,Yin Y,Zhu C,Du L,Elsayed AK,Li B

更新日期：2014-02-01 00:00:00

abstract：:Free cytoplasmic 40S mRNP particles from rat liver were treated with EDTA and separated into two populations of RNP particles with sedimentation maxima of 20S and 35S, respectively. A characteristic set of distinct scRNAs is found for 20S and 35S RNP particles. The sequences of two of the most abundant scRNAs from 20S...

journal_title：Molecular biology reports

authors： Villringer A,Kühn B,Schneider K,Andus T,Michels K,Northemann W,Krupp G,Walckhof B,Gross HJ,Klump H,Kroll A,Branlant C,Heinrich PC

更新日期：1983-05-01 00:00:00

abstract：:We report here cloning and characterization of a novel human gene, termed VMP, which is a vesicular membrane protein. RT-PCR analysis shows that VMP is expressed exclusively in brain of the 16 tissues examined, suggesting that it is a neuron-specific membrane protein. The cDNA encodes 195 amino acid with a putative mo...

journal_title：Molecular biology reports

authors： Cheng C,Xu J,Ye X,Dai J,Wu Q,Zeng L,Wang L,Zhao W,Ji C,Gu S,Xie Y,Mao Y

更新日期：2002-09-01 00:00:00

abstract：:Ventricular assist devices may function as a bridge to recovery or heart transplantation, however, little is known about its mechanisms. This study examined the role of matrix metalloproteinases (MMP)-tissue inhibitors of metalloproteinases (TIMP) axis in the process of recovery after unloading in a rat ischemic-induc...

journal_title：Molecular biology reports

authors： Wang WJ,Meng ZL,Mo YC,Liu JW,Sun CC,Hu SS,Zhang H

更新日期：2012-01-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00

abstract：:Quinone oxidoreductases (NAD(P)H): quinone oxidoreductase 1 (NQO1) and NRH: quinone oxidoreductase 2 (NQO2) are an antioxidant enzyme, important in the detoxification of environmental carcinogens. Methylene-tetra-hydrofolate reductase (MTHFR), plays a role in folate metabolism and may have oncogenic role through disru...

journal_title：Molecular biology reports

authors： Mandal RK,Nissar K,Mittal RD

更新日期：2012-12-01 00:00:00