Proteomics analysis of human brain tissue infected by street rabies virus.

abstract：:Several lines of evidence indicate that inflammatory processes play pivotal role in the development of intracranial aneurysm (IA). Recently, polymorphisms in the interleukin-12 (IL-12) gene were shown to be associated with immune-mediated inflammatory disease. The aim of this study was to investigate the interactions ...

journal_title：Molecular biology reports

authors： Li LJ,Pan XM,Sima X,Li ZH,Zhang LS,Sun H,Zhu Y,Liang WB,Gao LB,Zhang L

更新日期：2012-12-01 00:00:00

abstract：:Cytochrome P450 1B1 (CYP1B1) is a key P450 enzyme involved in the metabolism of exogenous and endogenous substrates in endocrine-mediated tumors such as prostate cancer. The potential significance of nonsynonymous SNP Leu432Val (rs1056836) as a risk factor in prostate cancer has been extensively studied. The objective...

journal_title：Molecular biology reports

authors： Cui L,Dillehay K,Chen W,Shen D,Dong Z,Li W

更新日期：2012-07-01 00:00:00

abstract：:J The [Ca2+] regulation of contractile ATPase flux, Jp, in skeletal muscle was analysed by computation of the Response R(Jp) Ca2+ for a 10 Hz range of electrical stimulation frequencies. Results of our analysis of the kinetic controls in ATP free energy metabolism in a network model of contracting muscle (J.A.L. Jenes...

journal_title：Molecular biology reports

authors： Jeneson JA

更新日期：2002-01-01 00:00:00

abstract：:Heavy metals pollution affects the nutritive value of fish. This study examined if the inclusion of dietary hempseed (HS) and hempseed oil (HO) in the diet of the fish could revert the copper-induced toxic effects on muscle fatty acid profile of rohu (Labeo rohita) and mrigal (Cirrhinus mrigala). Fingerlings of both s...

journal_title：Molecular biology reports

authors： Afridi AJ,Zuberi A,Yousafzai AM,Maria,Kamran M,Ullah S

更新日期：2019-02-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a world-wide health problem and its incidence accounts for 1.9-3.5% of all malignant tumors. Transforming growth factor beta/Smads (TGF-beta/Smads) signaling pathway plays an important role in oncogenesis, but its function and molecular mechanisms in OSCC remain unclear. Expressi...

journal_title：Molecular biology reports

authors： Wang X,Sun W,Bai J,Ma L,Yu Y,Geng J,Qi J,Shi Z,Fu S

更新日期：2009-05-01 00:00:00

abstract：:In jasmonate biosynthetic pathway, allene oxide synthase (AOS, EC 4.2.1.92), which is a cytochrome P450 (CYP74A), catalyzes the first committed step. We herein cloned a novel cDNA from Lonicera japonica Thunb., named LjAOS (GenBank accession: DQ303120), which was homologous to other AOSs. Southern blot analysis reveal...

journal_title：Molecular biology reports

authors： Jiang K,Pi Y,Hou R,Zeng H,Huang Z,Zhang Z,Sun X,Tang K

更新日期：2009-03-01 00:00:00

abstract：:The full length cDNA sequence of the Tpt1/TCTP (Tumor protein, Translationally-controlled1) gene was identified from Common Carp (Cyprinus carpio, Cyprinidae), and was designated as CcTpt1 gene. The CDS is 510 bp and encodes a 170-amino acid peptide with a typical Tpt1 signature 2 domain, and is a typical Tpt1 protein...

journal_title：Molecular biology reports

authors： Jiang L,Wang Y,Cheng A,Zhang B,Ma L,Liu Y,Sun X

更新日期：2013-10-13 00:00:00

abstract：:The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into a water-soluble, a ...

journal_title：Molecular biology reports

authors： Vermorken AJ,Weterings PJ,Bloemendal H

更新日期：1979-02-15 00:00:00

abstract：:The product of the OTUB1 gene is a member of the OTU superfamily of predicted cysteine proteases and inhibits cytokine gene transcription via its interaction with a ubiquitin protease and E3 ubiquitin ligase. To further understand the functions of the porcine OTUB1 gene, the subcellular localization of porcine OTUB1 p...

journal_title：Molecular biology reports

authors： Shan TL,Tang ZL,Guo DZ,Yang SL,Mu YL,Ma YH,Guan WJ,Li K

更新日期：2009-07-01 00:00:00

abstract：:RNA-protein interaction in the 30S subunits of rat liver hnRNP has been studied by crosslinking of informofer proteins to hnRNA induced by UV irradiation. Irradiation of 30S particles with 254 nm UV light in doses of 1 1 x 10(5) erg/mm2 leads to the extensive crosslinking hnRNA to informofer proteins. The crosslinked ...

journal_title：Molecular biology reports

authors： Marczinovits I,Molnár J

更新日期：1982-03-31 00:00:00

abstract：:Many case-control studies have investigated the role of TGF-β1 gene +869C/T promoter polymorphism in autoimmune diseases, but the results are inconsistent. To clarify this point, we performed a meta-analysis based on all available studies in Pubmed, Elsevier Science Direct, Google Searching, Chinese Biomedical Literat...

journal_title：Molecular biology reports

authors： Zhang L,Yan JW,Wang YX,Wan YN,Li JP,Liu P,Xu B,Wang BX,Peng WJ,Pan FM,Wang J

更新日期：2013-08-01 00:00:00

abstract：:The purpose of this study was to assess the value of cytokeratin 19 (CK19) and matrix metalloproteinase 2 (MMP-2) in predicting lymph node metastasis (LNM) and survival after curative resection in hepatocellular carcinoma (HCC) patients. Expression of CK19 and MMP-2 in tumor tissue was assessed through immunohistochem...

journal_title：Molecular biology reports

authors： Xiang ZL,Zeng ZC,Tang ZY,Fan J,Sun HC,Tan YS

更新日期：2011-06-01 00:00:00

abstract：:A double-stranded RNA-specific nuclease (ds RNase) has been isolated and partially purified from human placenta by DEAE-cellulose and DNA-cellulose column chromatography. Denatured DNA-cellulose retained most of the single-stranded RNA-specific nuclease (ss RNase) activity, whereas the ds RNase came out in the void vo...

journal_title：Molecular biology reports

authors： Kalyanaraman S,Maran A,Shanmugam G

更新日期：1983-08-01 00:00:00

abstract：:The relationship between genetic polymorphisms of glutathione S-transferase (GST) and the development of glioma has been investigated in several epidemiologic studies. However these studies report inconsistent results. In order to quantitatively summarise the evidence for such a relationship, a meta-analysis is conduc...

journal_title：Molecular biology reports

authors： Fan Z,Wu Y,Shen J,Zhan R

更新日期：2013-02-01 00:00:00

abstract：:CREB-regulated transcription coactivator 3 (CRTC3) was a recently identified protein which played an important role in glucose and lipid metabolism. Previous research showed that the polymorphisms of CRTC3 were associated with obesity in Mexican-Americans. Data on that relationship in Chinese was unavailable so far. S...

journal_title：Molecular biology reports

authors： Ou Z,Wang G,Li Q,Ma Z,Dai M,Zou F

更新日期：2014-01-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:Transcriptional activity is closely associated with DNA methylation and chromatin remodelling. Evidence is emerging that a family of methylation specific (methyl-CpG binding domain, MBD) proteins have the capacity to bind to methylated sequences and repress transcription. Recent advances in this area reveal that many ...

journal_title：Molecular biology reports

authors： El-Osta A,Baker EK,Wolffe AP

更新日期：2001-01-01 00:00:00

abstract：:Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis and metastasis. Here we evaluated the mechanism of action of P...

journal_title：Molecular biology reports

authors： Mancilla IA,Coatti GC,Biazi BI,Zanetti TA,Baranoski A,Marques LA,Corveloni AC,Lepri SR,Mantovani MS

更新日期：2019-12-01 00:00:00

abstract：:Recently, differentiated somatic cells had been reprogrammed to pluripotential state in vitro, and various tissue cells had been elicited from those cells. Epigenetic modifications allow differentiated cells to perpetuate the molecular memory needed for the cells to retain their identity. DNA methylation and histone d...

journal_title：Molecular biology reports

authors： Zhang XM,Li QM,Su DJ,Wang N,Shan ZY,Jin LH,Lei L

更新日期：2010-03-01 00:00:00

abstract：:Anti-EGFR monoclonal antibodies (anti-EGFR MoAbs) in metastatic colorectal cancer (mCRC) treatment are still not effective in all patients. This study aimed to evaluate the relationship between BRAF V600E mutation and the tumor response of anti-EGFR MoAbs for first-line treatment in mCRC patients. We searched the MEDL...

journal_title：Molecular biology reports

authors： Cui D,Cao D,Yang Y,Qiu M,Huang Y,Yi C

更新日期：2014-03-01 00:00:00

abstract：:Cardiomyocytes possess the ability to respond to mechanical stimuli by reprogramming their gene expression. This study investigated the effects of different loading protocols on signaling and expression responses of myogenic, anabolic, inflammatory, atrophy and pro-apoptotic genes in cardiomyocyte-like H9C2 cells. Dif...

journal_title：Molecular biology reports

authors： Zevolis E,Philippou A,Moustogiannis A,Chatzigeorgiou A,Koutsilieris M

更新日期：2021-01-04 00:00:00

abstract：:The cytotoxic T lymphocyte-associated antigen 4 gene (CTLA4) has a crucial role in regulation of T cell proliferation and mediates T cell apoptosis by encoding the T cell receptor. Schizophrenia (SCZ) patients often have abnormalities in terms of the function and development of the immune system. The aim of the presen...

journal_title：Molecular biology reports

authors： Kordi-Tamandani DM,Vaziri S,Dahmardeh N,Torkamanzehi A

更新日期：2013-08-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERP...

journal_title：Molecular biology reports

authors： An L,Yang T,Zhang Y,Lin Y,Zhang H,Jiao X,Hua L,Dai H,Wang C

更新日期：2012-02-01 00:00:00

abstract：:Consistent with its precloning characterization from the cellulolytic Bacillus sp., beta-1,4-endoglucanase purified from the recombinant E. coli exhibited maximum activity at 60 degrees C and pH 7.0. It was highly specific for CMC hydrolysis, with stability up to 70 degrees C and over a pH range of 6.0-8.0. The K(m) a...

journal_title：Molecular biology reports

authors： Afzal S,Saleem M,Yasmin R,Naz M,Imran M

更新日期：2010-04-01 00:00:00

abstract：:The cardiomyopathy associated 5 (CMYA5) gene was also called TRIM76, which was belonged to the tripartite motif super family of proteins (TRIM). It was a direct transcriptional target for MEF2A and it played an important role in myofibrillogenesis. In the present study, a 12056 bp cDNA sequence of the porcine CMYA5 ge...

journal_title：Molecular biology reports

authors： Xu X,Xu X,Yin Q,Sun L,Liu B,Wang Y

更新日期：2011-03-01 00:00:00

abstract：:Schizophrenia is one of the neuropathological disorders, which are associated with dopamine and its receptors. In recent years, it has been shown that mRNA of D3, D4 and D5 dopamine receptor (DRD3, DRD4, DRD5) subtypes is expressed in human peripheral blood lymphocytes (PBL). A total 55 schizophrenic patients and 51 h...

journal_title：Molecular biology reports

authors： Urhan-Kucuk M,Erdal ME,Ozen ME,Kul S,Herken H

更新日期：2011-04-01 00:00:00

abstract：:Many studies have been performed to identify regulatory circuit underlying plant stress tolerance. However, the reliability of some findings has been criticized because of exclusive use of stress sensitive plant species such as Arabidopsis thaliana. Sensitive plant species often harbor narrow defensive mechanisms and ...

journal_title：Molecular biology reports

authors： Shamloo-Dashtpagerdi R,Razi H,Ebrahimie E,Niazi A

更新日期：2018-10-01 00:00:00

abstract：:β-Catenin plays a crucial role in embryonic development and responds to the activation of several signal transduction pathways. In this paper, in order to understand the functions of β-catenin gene in early embryonic development of Artemia sinica, the complete cDNA sequence was cloned for the first time using RACE tec...

journal_title：Molecular biology reports

authors： Li X,Hou L,Ma J,Liu Y,Zheng L,Zou X

更新日期：2012-01-01 00:00:00

abstract：:Several studies have examined the effects of the tumor necrosis factor-α (TNF-α) -308 A/G and lymphotoxin-α (LT-α) +252 A/G polymorphisms on susceptibility to sarcoidosis, showing mixed results. The purpose of this study was to examine whether the TNF-α -308 A/G and LT-α +252 A/G polymorphisms confer susceptibility to...

journal_title：Molecular biology reports

authors： Song GG,Kim JH,Lee YH

更新日期：2014-01-01 00:00:00

abstract：:BACs-on-Beads (BoBs™) assay is a rapid aneuploidy test (RAT) that detects numerical chromosomal aneuploidies and multiple microdeletion/microduplication syndromes. This study was conducted to appraise the usefulness of the BoB™ assay as a complementary diagnostic tool to conventional karyotyping for the rapid detectio...

journal_title：Molecular biology reports

authors： Farra C,Nassar AH,Mirza F,Abdouni L,Souaid M,Awwad J

更新日期：2020-01-01 00:00:00