CTLA-4 exon 1 +49 polymorphism alone and in a haplotype with -318 promoter polymorphism may confer susceptibility to chronic HBV infection in Chinese Han patients.

abstract：:Gibberellic acid (GA) is involved in the regulation of plant growth and development. We defined GA-stimulated transcript (GAST) gene family and characterized its four members (TaGAST1, 2, 3, and 4) in wheat spikes. Triticum aestivum whole spikes were collected at ten developmental stages and dehulled spikelets were ob...

journal_title：Molecular biology reports

authors： Kim YJ,Kim JY,Yoon JS,Kim DY,Hong MJ,Seo YW

更新日期：2016-12-01 00:00:00

abstract：:The glycosylation of UDP-glucosyltransferases (UGTs) is of great importance in the control and elimination of both endogenous and exogenous toxins. Bm-UGT10286 (UGT86) is the sole provider of UGT activity against the 5-O position of quercetin and directly influences the formation of green pigment in the Bombyx cocoon....

journal_title：Molecular biology reports

authors： Xu X,Wang M,Wang Y,Sima Y,Zhang D,Li J,Yin W,Xu S

更新日期：2013-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) can be classified into six major genotypes. The HCV genotypes variability accounts for its geographical distribution, its responses to treatments and the clinical outcomes. The aim of this study was to determine the distribution of HCV genotypes among volunteer blood donors in Thailand. Samples...

journal_title：Molecular biology reports

authors： Sistayanarain A,Kunthalert D,Vipsoongnern Y

更新日期：2011-10-01 00:00:00

abstract：:The objective of this study was to analyze possible associations between single nucleotide polymorphisms (SNPs) in the Myf5 gene with chicken growth and reproductive traits. SNPs in Myf5 of the Jinghai yellow chicken were detected by the polymerase chain reaction single-strand conformation polymorphism method and the ...

journal_title：Molecular biology reports

authors： Tang Y,Zhang T,Zhang G,Wang J,Fan Q,Chen X,Wei Y,Han K,Wang Y

更新日期：2014-10-01 00:00:00

abstract：:The human COX-2 promoter contains a direct repeat 1 (DR1) which was shown to confer responsiveness to PPARs. We found that in AN(3)CA and F9 cells, this hCOX-2 DR1 mediates responsiveness to all-trans-retinoic acid (tRA) or 9-cis-retinoic acid (9cRA), but this effect was suppressed by PPARδ. Truncated PPARδ lacking th...

journal_title：Molecular biology reports

authors： Han K,Moon I,Lim HJ

更新日期：2011-02-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:Diacylglycerol acyltransferase (DGAT) plays a critical role in the synthesis of triacylglycerol. In this study, PCR-SSCP and DNA sequencing methods were employed to screen the genetic variations of DGAT-2 gene in 299 goats from three breeds (Boer goat, Chinese Xuhuai white goat and Chinese Haimen goat). Three fragment...

journal_title：Molecular biology reports

authors： Fang X,Zhang J,Xu H,Zhang C,Du Y,Shi X,Chen D,Sun J,Jin Q,Lan X,Chen H

更新日期：2012-02-01 00:00:00

abstract：:β-Catenin plays a crucial role in embryonic development and responds to the activation of several signal transduction pathways. In this paper, in order to understand the functions of β-catenin gene in early embryonic development of Artemia sinica, the complete cDNA sequence was cloned for the first time using RACE tec...

journal_title：Molecular biology reports

authors： Li X,Hou L,Ma J,Liu Y,Zheng L,Zou X

更新日期：2012-01-01 00:00:00

abstract：:Mucopolysaccharidosis IV A (MPS IV A) is a lysosomal storage disease produced by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme. Although genotype-phenotype correlations have been reported, these approaches have not enabled to establish a complete genotype-phenotype correlation, and they ha...

journal_title：Molecular biology reports

authors： Olarte-Avellaneda S,Rodríguez-López A,Alméciga-Díaz CJ,Barrera LA

更新日期：2014-11-01 00:00:00

abstract：:Etiological factors for coronary artery disease (CAD) involve a wide range of gene and environmental interactions. One of the systems being implicated in the pathophysiology of CAD is the renin-angiotensin system (RAS). However, the genetic polymorphisms of this system have not been widely studied in Iranian patients ...

journal_title：Molecular biology reports

authors： Firouzabadi N,Tajik N,Bahramali E,Bakhshandeh H,Maadani M,Shafiei M

更新日期：2013-08-01 00:00:00

abstract：:We report the characterization of VvIAA9, an auxin/indole-3-acetic acid (Aux/IAA) protein, in grapevine (Vitis vinifera L.). VvIAA9 was expressed abundantly in leaves and berries. VvIAA9 transcription was drastically upregulated from anthesis to onset of ripening (termed véraison), in which berry diameter rapidly incr...

journal_title：Molecular biology reports

authors： Fujita K,Horiuchi H,Takato H,Kohno M,Suzuki S

更新日期：2012-07-01 00:00:00

abstract：:J The [Ca2+] regulation of contractile ATPase flux, Jp, in skeletal muscle was analysed by computation of the Response R(Jp) Ca2+ for a 10 Hz range of electrical stimulation frequencies. Results of our analysis of the kinetic controls in ATP free energy metabolism in a network model of contracting muscle (J.A.L. Jenes...

journal_title：Molecular biology reports

authors： Jeneson JA

更新日期：2002-01-01 00:00:00

abstract：:Synthetic hexaploid (SH) wheat derived from crossing tetraploid durum wheat and diploid Aegilops tauschii provide germplasm for wheat improvement as the conventional wheat varieties possess very low genetic diversity. This study aims to identify diverse SH lines which can be used in breeding programs for transferring ...

journal_title：Molecular biology reports

authors： Shakeel M,Ilyas M,Kazi M

更新日期：2013-01-01 00:00:00

abstract：:Glioma is the most aggressive primary brain tumor. We have previously provided evidence that IFITM3 promoted glioma cells migration. However, the mechanism of how IFITM3 regulates glioma cells invasion and whether IFITM3 participates in TGF-β-mediated glioma invasion are still unknown. In this paper, we proved that IF...

journal_title：Molecular biology reports

authors： Wang H,Tang F,Bian E,Zhang Y,Ji X,Yang Z,Zhao B

更新日期：2020-01-01 00:00:00

abstract：:Various case-control studies have shown association of single nucleotide polymorphism rs12303764(G/T) in ULK1 with crohn's disease. The techniques used in these studies were time consuming, complicated and require sophisticated/expensive instruments. Therefore, in order to overcome these problems, we have developed a ...

journal_title：Molecular biology reports

authors： Randhawa R,Duseja A,Changotra H

更新日期：2017-02-01 00:00:00

abstract：:RNase MRP is a ribonucleoprotein enzyme with a structure similar to RNase P. It is required for normal processing of precursor rRNA, cleaving it in the Internal Transcribed Spacer 1. ...

journal_title：Molecular biology reports

authors： Lindahl L,Zengel JM

更新日期：1995-01-01 00:00:00

abstract：:The cardiomyopathy associated 5 (CMYA5) gene was also called TRIM76, which was belonged to the tripartite motif super family of proteins (TRIM). It was a direct transcriptional target for MEF2A and it played an important role in myofibrillogenesis. In the present study, a 12056 bp cDNA sequence of the porcine CMYA5 ge...

journal_title：Molecular biology reports

authors： Xu X,Xu X,Yin Q,Sun L,Liu B,Wang Y

更新日期：2011-03-01 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：:Yangyin Tongnao granules (YYTNG) have been extensively applied in the treatment of brain injury, mainly due to its antioxidant effects, inhibition of apoptosis, and enhancement of blood circulation. To analyze the effect of YYTNG on the recovery of neurological function and neurogenesis in the peri-infarct area after ...

journal_title：Molecular biology reports

authors： Wang Y,Yang J,Du H,Zhang H,Wan H,He Y

更新日期：2019-08-01 00:00:00

abstract：:In the present study, Amukkara Chooram (AC) a well known herbal medicine was investigated for their antibiofilm efficacy against biofilm of Candida albicans. The biofilm inhibitory concentration of 20 µg/mL of AC showed promising effect by inhibiting the biofilm upto 60%. Morphogenic transition state of C. albicans fr...

journal_title：Molecular biology reports

authors： Rajamohamed BS,Siddharthan S

更新日期：2019-06-01 00:00:00

abstract：:Schizophrenia is a chronic and neuropsychiatric disease that affects about 0.5-1% of the world's population. An increase in dopamine and dopamine D2 receptor (DRD2) gene products has been well described in schizophrenic patients. Several groups have studied the relationship between dopaminergic hyperactivity and cellu...

journal_title：Molecular biology reports

authors： Kurt H,Dikmen M,Basaran A,Yenilmez C,Ozdemir F,Degirmenci I,Gunes HV,Kucuk MU,Mutlu F

更新日期：2011-02-01 00:00:00

abstract：:Stomatal closure is a common adaptation response of plants to the onset of drought condition and its regulation is controlled by transcription factors. MYB60, a transcription factor involved in the regulation of light-induced stomatal opening, has been characterized in arabidopsis and grapevine. In this work, we studi...

journal_title：Molecular biology reports

authors： Rodríguez-Hoces de la Guardia A,Ugalde MB,Lobos-Diaz V,Romero-Romero JL,Meyer-Regueiro C,Inostroza-Blancheteau C,Reyes-Diaz M,Aquea F,Arce-Johnson P

更新日期：2021-01-27 00:00:00

abstract：:Interleukin-13 (IL-13) is a TH2 cytokine with direct and indirect immunoregulatory functions on cancer cells. The cytokine has been reported to have some polymorphic variations at the gene level associated with some immune related diseases including asthma and allergy. In the present study, association of three IL13 g...

journal_title：Molecular biology reports

authors： Faghih Z,Erfani N,Razmkhah M,Sameni S,Talei A,Ghaderi A

更新日期：2009-09-01 00:00:00

abstract：:Mitochondrial dysfunction plays a crucial role in the central pathogenesis of insulin resistance and type 2 diabetes mellitus. Macrophages play important roles in the pathogenesis of insulin resistance. Lauric acid is a 12-carbon medium chain fatty acid (MCFA) found abundantly in coconut oil or palm kernel oil and it ...

journal_title：Molecular biology reports

authors： Tham YY,Choo QC,Muhammad TST,Chew CH

更新日期：2020-12-01 00:00:00

abstract：:Substantial epidemiological studies have shown an association of obesity with the common gynecological malignancy, endometrial cancer. The relevant interactions and contribution of estradiol and the adipose cytokine, leptin, in endometrial lesions are not completely understood. Suitable animal models to understand the...

journal_title：Molecular biology reports

authors： Shetty A,Venkatesh T,Tsutsumi R,Suresh PS

更新日期：2020-01-01 00:00:00

abstract：:HIV/AIDS remains to be one of the killing diseases of mankind. Host genetic response is one of the factor which determine susceptibility to HIV and disease progression to AIDS. The aim of the present study was to evaluate the impact of ERCC2 Lyc ( 751 ) Gln (excision repair cross complementing rodent repair deficiency...

journal_title：Molecular biology reports

authors： Sobti RC,Berhane N,Mahdi SA,Kler R,Hosseini SA,Kuttiat V,Wanchu A

更新日期：2011-06-01 00:00:00

abstract：:Several lines of evidence suggest that the ubiquitin-proteasome pathway is involved in sepsis-induced muscle catabolism. The gene expression of ubiquitin and several of the proteasome subunits was increased in muscle from both septic rats and patients. In other studies, the activity of isolated 20S proteasomes was sti...

journal_title：Molecular biology reports

authors： Hasselgren PO

更新日期：1999-04-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) has been investigated extensively at the molecular level. Nevertheless, genome wide study on the temporal and spatial dynamics of the virus is non-existed. To explore this topic, we determined complete coding genome sequences for four PRRSV isolates and analy...

journal_title：Molecular biology reports

authors： Yoon SH,Kim H,Kim J,Lee HK,Park B,Kim H

更新日期：2013-10-12 00:00:00

abstract：:Long terminal repeat (LTR)-retrotransposons are mobile genetic elements that are ubiquitous in plants and constitute a major portion of their nuclear genomes. LTR- retrotransposons possess unique properties that make them appropriate for investigating relationships between populations, varieties and closely related sp...

journal_title：Molecular biology reports

authors： Woodrow P,Pontecorvo G,Ciarmiello LF

更新日期：2012-04-01 00:00:00