Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages.

abstract：:Based on the internal transcribed spacer and inter-simple sequence repeats (ISSR), the phylogenetic relationship and genetic diversity of Metarhizium spp., pathogens found in Chinese burrower bugs, Schiodtella formosana, were analyzed. The results showed that the causative agents of the epizootic green muscardine dise...

journal_title：Molecular biology reports

authors： Luan F,Zhang S,Wang B,Huang B,Li Z

更新日期：2013-01-01 00:00:00

abstract：:A nucleic acid sequence MC, encoding Momordica Chanrantia anti-hyperglycaemic peptide MC6 (accession: AAX06814) synthesized according to Escherichia coli preferred codons, was cloned and expressed in E. coli. Recombinant protein pQE8-MC (about 3.5 kDa) was purified and analyzed by 20% SDS-PAGE and western blot. It rev...

journal_title：Molecular biology reports

authors： Liu SX,Fu ZP,Mu RM,Hu ZB,Wang FJ,Wang XR

更新日期：2010-04-01 00:00:00

abstract：:Myopalladin (MYPN) and titin (TTN) play key roles in skeletal muscle structural organisation and for this reason they may be functional candidates for meat production traits in pigs. We analysed by PCR-RFLP two polymorphisms previously identified and described in the 3'UTR of MYPN and TTN genes in a group of Italian L...

journal_title：Molecular biology reports

authors： Braglia S,Davoli R,Zappavigna A,Zambonelli P,Buttazzoni L,Gallo M,Russo V

更新日期：2013-12-01 00:00:00

abstract：:Type 2 diabetes is one of the most prevalent diseases, which increases resistance to insulin in target tissues. The measurement of miRNAs quantity is a molecular approach for diagnosis of diabetes. miRNAs are small non-coding RNA strings of 21-23 long nucleotides that act as inhibitors in proteins translation. Several...

journal_title：Molecular biology reports

authors： Andoorfar S,Hosseini Tafreshi SA,Rezvani Z

更新日期：2019-10-01 00:00:00

abstract：:Stable inheritance and expression of transgene are important parameters for successful use of a transgenic crop. We previously transformed a Bt cry1Ba3 gene into cabbage inbred line CA21-3. To evaluate the stability of our Bt cabbage lineages, transgene inheritance and expression were examined in four successive gener...

journal_title：Molecular biology reports

authors： Yi DX,Fang ZY,Yang LM

更新日期：2020-04-01 00:00:00

abstract：:To explore the relationship of Notch1 mutation in T-ALL with the survival rate of T-ALL patients. The PubMed database, the Cochrane Library, conference proceedings, EMBASE databases, and references of published trials and review articles were searched. Two reviewers independently assessed the quality of the trials and...

journal_title：Molecular biology reports

authors： Ma J,Wu M

更新日期：2012-05-01 00:00:00

abstract：:Several lines of evidence suggest that the ubiquitin-proteasome pathway is involved in sepsis-induced muscle catabolism. The gene expression of ubiquitin and several of the proteasome subunits was increased in muscle from both septic rats and patients. In other studies, the activity of isolated 20S proteasomes was sti...

journal_title：Molecular biology reports

authors： Hasselgren PO

更新日期：1999-04-01 00:00:00

abstract：:The objective of this study was to estimate the impact of the polymorphism of μ-calpain (CAPN1S) gene on protein changes of the cattle muscle tissue and its tenderness during 10-day cold storage. The analysis was performed on the longest dorsal and lumbar muscles collected from 76 bulls 6 to 12 months of age. Polymorp...

journal_title：Molecular biology reports

authors： Iwanowska A,Grześ B,Mikołajczak B,Iwańska E,Juszczuk-Kubiak E,Rosochacki SJ,Pospiech E

更新日期：2011-02-01 00:00:00

abstract：:As initial steps to define how the 26S proteasome degrades ubiquitinated proteins in plants, we have characterized many of the subunits that comprise the proteolytic complex from Arabidopsis thaliana. A set of 23 Arabidopsis genes encoding the full complement of core particle (CP) subunits and a collection encoding 12...

journal_title：Molecular biology reports

authors： Fu H,Girod PA,Doelling JH,van Nocker S,Hochstrasser M,Finley D,Vierstra RD

更新日期：1999-04-01 00:00:00

abstract：:Fatty acid-binding proteins (FABPs), small cytosolic proteins that function in the uptake and utilization of fatty acids, have been extensively studied in higher vertebrates while invertebrates have received little attention despite similar nutritional requirements during periods of reproductive activity. Therefore, a...

journal_title：Molecular biology reports

authors： Li WW,Jin XK,He L,Gong YN,Jiang H,Wang Q

更新日期：2011-11-01 00:00:00

abstract：:Maintenance of glucose homeostasis is reciprocally regulated by insulin and glucagon-like peptide-1 (GLP-1). We previously reported that GLP-1 secretion in response to an oral glucose load was impaired following an administration of 3-deoxyglucosone (3DG), an independent factor associated with the development of pre-d...

journal_title：Molecular biology reports

authors： Song X,Zhou L,Xu H,Wang F,Liang G,Zhang L,Huang F,Jiang G

更新日期：2019-10-01 00:00:00

abstract：:F-box proteins are key components of the ubiquitin (Ub)/26S proteasome pathway that mediates selective degradation of regulatory proteins involved in a wide variety of cellular processes affecting eukaryotic cells. In plants, F-box genes form one of the largest multigene superfamilies and control many important biolog...

journal_title：Molecular biology reports

authors： Paquis S,Mazeyrat-Gourbeyre F,Fernandez O,Crouzet J,Clément C,Baillieul F,Dorey S

更新日期：2011-06-01 00:00:00

abstract：:The Follicle stimulating hormone beta polypeptide (FSHβ) gene has been investigated as a candidate gene for litter size because of its role in maturation of small and medium follicles into ovulating large follicles. Genes coding follicle stimulating hormone have been found to have significant effects on litter size in...

journal_title：Molecular biology reports

authors： Magotra A,Naskar S,Das B,Ahmad T

更新日期：2015-02-01 00:00:00

abstract：:The present study brings out the preventive role of (-)-epigallocatechin-gallate (EGCG) on cardiac mitochondrial metabolism and apoptosis in cigarette smoke (CS)-exposed rats. The CS-exposed rats showed significantly decreased activities of TCA cycle enzymes and mitochondrial enzymatic antioxidants, on the other hand,...

journal_title：Molecular biology reports

authors： Adikesavan G,Vinayagam MM,Abdulrahman LA,Chinnasamy T

更新日期：2013-12-01 00:00:00

abstract：:Tall fescue is a perennial cool-season grass with economic importance especially in temperate regions of the northern hemisphere. This study was done to assess the genetic diversity and population structure of 90 tall fescue populations and cultivars using ISSR and EST-SSR markers in order to categorize valuable popul...

journal_title：Molecular biology reports

authors： Shahabzadeh Z,Mohammadi R,Darvishzadeh R,Jaffari M

更新日期：2020-01-01 00:00:00

abstract：:Complexity is one of the hallmarks that applies to C2H2 type zinc finger proteins (ZFPs). Structurally distinct clusters of zinc finger modules define an extremely large superfamily of nucleic acid binding proteins with several hundred, perhaps thousands of different members in vertebrates. Recent discoveries have pro...

journal_title：Molecular biology reports

authors： Pieler T,Bellefroid E

更新日期：1994-07-01 00:00:00

abstract：:The widely studied candidate genes of the renin-angiotensin-aldosterone system, angiotensinogen (AGT), and angiotensin II receptor type 1 (AGTR1), are implicated in the development of diabetic nephropathy (DN). A number of studies have evaluated the association between the functional polymorphisms, AGT M235T and AGTR1...

journal_title：Molecular biology reports

authors： Ding W,Wang F,Fang Q,Zhang M,Chen J,Gu Y

更新日期：2012-02-01 00:00:00

abstract：:Two DREB-like genes, designated as DmDREBa and DmDREBb, were isolated from chrysanthemum by RACE approach. The DmDREBa and DmDREBb genes encoded proteins of 191 and 185 amino acid residues with the predicted molecular mass of 21.66 and 20.99 kDa, respectively. Both DmDREBs proteins comprised a typical EREBP/AP2 domain...

journal_title：Molecular biology reports

authors： Yang Y,Wu J,Zhu K,Liu L,Chen F,Yu D

更新日期：2009-01-01 00:00:00

abstract：:Random amplified polymorphic DNA (RAPD) and microsatellite markers were applied to evaluate the genetic variation in endemic and endangered yellow catfish, Horabagrus brachysoma sampled from three geographic locations of Western Ghat, South India river systems. In RAPD, of 32 10-mer RAPD primers screened initially, 10...

journal_title：Molecular biology reports

authors： Abdul Muneer PM,Gopalakrishnan A,Musammilu KK,Mohindra V,Lal KK,Basheer VS,Lakra WS

更新日期：2009-09-01 00:00:00

abstract：:Diabetes affects a variety of tissues including the central nervous system; moreover, some evidence indicates that memory and learning processes are disrupted. Also, oxidative stress triggers alterations in different tissues including the brain. Recent studies indicate mitochondria dysfunction is a pivotal factor for ...

journal_title：Molecular biology reports

authors： Osorio-Paz I,Ramírez-Pérez G,Hernández-Ramírez JE,Uribe-Carvajal S,Salceda R

更新日期：2018-10-01 00:00:00

abstract：:Initially, we isolated the caffeic acid O-methyltransferase (COMT) gene from Miscanthus sinensis (accession number HM062766.1). Next, we produced transgenic tobacco plants with down-regulated COMT gene expression to study its control of total phenol and lignin content and to perform morphological analysis. These trans...

journal_title：Molecular biology reports

authors： Seong ES,Yoo JH,Lee JG,Kim HY,Hwang IS,Heo K,Kim JK,Lim JD,Sacks EJ,Yu CY

更新日期：2013-02-01 00:00:00

abstract：:Nonspecific lipid transfer protein (nsLTP) is usually basic and secreted low-molecular-mass protein in plants. The 3-D structure of nsLTP1 resembles that of elicitin produced by the plant pathogen Phytophthora cryptogea, which can bind to the plant plasma membrane putative receptor and activate the downstream response...

journal_title：Molecular biology reports

authors： Wang X,Wang H,Li Y,Cao K,Ge X

更新日期：2009-04-01 00:00:00

abstract：:ATP-binding cassette transporter A1 (ABCA1) modulates plasma levels of high density lipoprotein (HDL), a cardiovascular protecting factor. Tree shrew was considered to be an animal protected from atherosclerosis characterized by high proportion of HDL in plasma. The cDNA clones and expression of tree shrew ABCA1 was i...

journal_title：Molecular biology reports

authors： Zeng WW,Zhou B,Liu HR,Sun GT,Chen BS

更新日期：2009-03-01 00:00:00

abstract：:To investigate mechanisms of rat glutathione S-transferase P1 gene (rGSTP1) expression regulation during chemical carcinogenesis. we studied enhancer elements located in the region between -2.5 kb to -2.2 kb. The region was upstream from the start site of transcription and was divided into two major fragments, GPEI an...

journal_title：Molecular biology reports

authors： Liu D,Liao M,Zuo J,Henner WD,Fan F

更新日期：2001-03-01 00:00:00

abstract：:Male Breast Cancer (MBC) is a rare and aggressive disease that is associated with genetic factors. Mutations in BRCA1 and BRCA2 account for 10% of all MBC cases suggesting that other genetic factors are involved. The aim of the present study is to screen whole BRCA1 and BRCA2 exons using the Ampliseq BRCA panel in Tun...

journal_title：Molecular biology reports

authors： Ben Kridis-Rejeb W,Ben Ayed-Guerfali D,Ammous-Boukhris N,Ayadi W,Kifagi C,Charfi S,Saguem I,Sellami-Boudawara T,Daoud J,Khanfir A,Mokdad-Gargouri R

更新日期：2020-09-01 00:00:00

abstract：:Molluscs are an extraordinarily diverse group of animals and to discriminate them based on one molecular marker/gene is very difficult because of the too fast or slow rate of nucleotide substitution. In the study, the tropomyosin cds (coding sequences) of 43 animal species were analyzed, the results of which suggested...

journal_title：Molecular biology reports

authors： Wang X,Li L,Xu F,Zhang G

更新日期：2011-10-01 00:00:00

abstract：:The circular dichroism spectra of poly(dG). poly(dC) have been studied as a function of pH in 0.15 M NaCl solution. Acid titration to pH 2.5 showed two transitions, one around pH 5, the second below pH 3. These transitions are disproportionation reactions and are not due to the dissociation of the complexes. Alkaline ...

journal_title：Molecular biology reports

authors： Thiele D,Sarocchi MT,Guschlbauer W,Marck C

更新日期：1973-10-01 00:00:00

abstract：:This novel orange fluorescent protein (OFP) emits brilliant orange fluorescent light. OFP has high fluorescence quantum yield, fast maturation rate, and stability, which imply this protein should be the most favorable biotechnological tools used to investigate the function of target gene by visualizing, monitoring, an...

journal_title：Molecular biology reports

authors： Liu JM,David WC,Ip DT,Li XH,Li GL,Wu XF,Yue WF,Zhang CX,Miao YG

更新日期：2009-02-01 00:00:00

abstract：:One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which encodes the major t...

journal_title：Molecular biology reports

authors： Seven M,Batar B,Unal S,Yesil G,Yuksel A,Guven M

更新日期：2014-01-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00