Abstract：
:Driving under the influence of alcohol (DUIA) and drugs (DUID) is considered an elevated risk for traffic safety. When assessing a driver's fitness to drive, standardized and objective measurement methods are still required, in order to clarify the question whether an individual is under the influence of substances acting on the central nervous system (CNS). We exposed healthy test subjects (n=41) as well as persons who were under the influence of cannabis after repeated inhalation to multiple light stimuli using infrared technology and measured the pupillary light reflex (PLR). Toxicological tests of blood samples taken from every subject followed. The aims of this study were to assess the differences in pupillography response between cannabis consumers after a washout period and no cannabis consumers as well as the dose related effects on pupillography parameters of cannabis in cannabis consumers. All four pupillary parameters changed according to a weakened pupil function after acute administration of cannabis in all test subjects. Furthermore, it could be observed that habitual cannabis consumers showed an altered pupillary function just before the first dose was taken, suggesting that the long-term effects and addiction also have to be taken into account, when effects of the CNS are discussed. The results of the present study show that almost all pupil parameters could be reliable indicators for the detection of subjects under the acute effect of cannabis.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Campobasso CP,De Micco F,Corbi G,Keller T,Hartung B,Daldrup T,Monticelli Fdoi
10.1016/j.forsciint.2020.110559subject
Has Abstractpub_date
2020-12-01 00:00:00pages
110559eissn
0379-0738issn
1872-6283pii
S0379-0738(20)30421-7journal_volume
317pub_type
杂志文章abstract：:Investigating crimes against children, specifically sexual solicitations, are complicated because not all offenders are contact-driven, meaning they want to meet the minor for sex in the physical world; instead, some offenders are fantasy-driven, in that they are more interested in cybersex and role-play. In addition,...
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journal_title：Forensic science international
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journal_title：Forensic science international
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journal_title：Forensic science international
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journal_title：Forensic science international
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pub_type： 杂志文章
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doi：10.1016/j.forsciint.2007.05.020
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journal_title：Forensic science international
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journal_title：Forensic science international
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journal_title：Forensic science international
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